Neurology is the branch of science and medicine dealing with the central and peripheral nervous system. The nervous system is made of the brain and spinal cord. The disorders, illness or injuries of the nervous system can become problematic for people suffering from them. One of the worst diseases of the nervous system is Parkinson s disease.

It is a progressive disorder affecting the central nervous system that leads to slowing down of movement and slurring of speech over a period of time. It is a condition where the nerve cells in the brain producing dopamine (a neurotransmitter) are affected.

Some of the early signs of Parkinson s include:

Tremor: If you have noticed a slight shaking of your hands or limbs, then Parkinson s might be the cause. The trembling can range from mild to severe as the disease progresses. The back-and-forth rubbing of your thumb and forefinger is known as pill-rolling tremor. One of the most prominent signs is your hand shaking even when it is rested.
Bradykinesia (slow movement): As the disease progresses, you may find it difficult to move your hands or legs or going from one place to another. Even making the smallest movement will require an increased effort on your part.
Rigid Muscles: The muscles in your body can become stiff causing you pain and making it difficult to perform physical activities.
Masked Face: Your face may experience spasms or become stiff periodically. It can also lead to complete paralysis on one side of the face.
Stooping or improper balance: Having Parkinson s disease can make your body posture imbalanced resulting in stooping or hunching over.
Decreased Automatic Movements: You may experience difficulty in smiling, blinking or swinging your arms while walking.
Alteration in voice or speaking: Your voice can become soft or you may slur while talking. You can also experience a monotonous voice.
Writing may become small: You can experience changes in your handwriting as it becomes small and crowded.
Loss of Smell: The smell of food sitting right in front of you may not register in your olfactory resulting in loss of appetite.
Constipation: Having Parkinson s disease can lead to patients experiencing irritable bowel syndrome.
Have Trouble Sleeping: It might be difficult to fall asleep for people suffering from Parkinson s. Also, there are sudden movements during the sleeping process.
Dizziness: People suffering from Parkinson s may faint from time to time.
These were some of the symptoms and signs by which you can tell whether a person has Parkinson s or not. However, as of now it is not curable and can only be treated with medicines. But, early detection can definitely help in preventing it from affecting the whole body.

Parkinson's Disease - Are You Aware Of These Signs?

Women are not really sure about frozen embryos  ability to result in pregnancy. Ironically, the success of Frozen Embryo Transfer has dramatically improved over the last few years. In the days gone by, the chance of women getting pregnant through the use of frozen embryos seemed to be on the lower side compared to that from the transfer of fresh embryos. Recent data related to this suggests that this is no longer the case.

Reasons behind the low success rate of frozen embryo transfer in the past
Previously during the frozen embryo transfer process, the embryos which had to get frozen were the ones that did not get chosen for the fresh embryo transfer initially. The reason being that the embryologist had gone ahead to choose the best possible embryos for getting them transferred initially. As far as the fresh embryo transfer is concerned, quality of embryo has got a major effect on the chance of a woman getting pregnant. On the other hand, if quality of embryos frozen is not good, the rate of survival after it gets thawed along with the rate of pregnancy would be on the lower side.

The second important reason is the amount of embryos that got transferred. Let us consider a couple who produce four very good quality embryos. Two of them are transferred during fresh In Vitro Fertilization Process and the remaining two are frozen. This leads to pregnancy and the woman gives birth to a baby. Later on, the couple once again decides to go for pregnancy by using the frozen embryos. Though only one embryo survives after getting thawed. The frozen embryo transfer is that of a single embryo. The success rate of a frozen embryo transfer through a single embryo is always going to be on the lower side than what it will be when multiple embryo transfer is involved.

Finally the method of freezing embryos has seen a sea change quite a number of years ago. Nowadays the freezing of embryos takes place by a fast method, known as vitrification. This process has got a much better survival rate when embryos get thawed along with good rates of pregnancy when those particular embryos are transferred in a much better manner.

Studies about high success rate of frozen embryo transfer
There have been studies performed in women, who have had quite a vigorous stimulation of their ovaries and were considered to be at high risk for Ovarian Hyperstimulation Syndrome. The physicians took the decision of skipping the process of embryo transfer and instead go ahead to freeze all the embryos for use at a later stage.

This tends to significantly decrease the risk of having serious Ovarian Hyperstimulation Syndrome along with decrease in complications. Other cases involved, physicians deciding to move on with a fresh embryo transfer depite the risk of Ovarian Hyperstimulation Syndrome. In both the scenarios the couples have quite a large number of embryos and the embryos selected for transfer were the best embryos.

The studies have shown no difference in the rates of pregnancy between fresh or frozen embryos or for that matter higher rate of pregnancy with frozen embryos.

How Successful Is Frozen Embryo Transfer?

Both schizophrenia and autism are considered to be neurological disorders resulting from atypical neural development, occurring due to a variety of causes. Both these disorders have a genetic predisposition that may be due to environmental factors. However, there are a few basic differences between the two disease conditions.

Autism is also known as Autism Spectrum Disorder (ASD), is a neurodevelopmental disorder characterized by a spectrum of abnormal behaviour. They include persistent deficits in social communication and interaction, along with restricted and repetitive patterns of behaviour, interests or activities.

Signs of autism in babies

By 6 months - No social smiles or other warm, joyful expressions; limited to no eye contact
By 9 months - No sharing of vocal sounds
By 12 months - No babbling or use of gestures to communicate; not responding to one s name when called
By 16 months - No use of words
By 24 months - No meaningful or two-word phrases
Signs of autism at any age

Avoids eye contact and wants to be alone
Finds it difficult to understand other people s feelings
Speaks very less or has delayed language development
Echolalia - Repeats words or phrases
Cannot accept change in routine or surroundings
Performs repetitive behaviours like flapping or rocking
Has restricted interests and hobbies
Reacts unusually intense to sounds, smells, tastes, lights, colours etc.
Schizophrenia
Schizophrenia is a neuropsychiatric disorder that begins during late adolescence and early adulthood. It is characterized by delusions, hallucinations, disorganized speech and behavioural changes that cause social and occupational dysfunctions.

Signs of Schizophrenia

The symptoms of schizophrenia are usually observed between ages 16 and 30, such as e.g. delusions, hallucinations, thought disorders, movement disorders etc.
Delusions are false beliefs of the patient that may take many forms like delusions of persecution or grandeur. You may feel somebody is controlling you or may think you have extraordinary powers and abilities.
Hallucinations are when the patient hears voices more than seeing, feeling, tasting or smelling random things, which are not actually there.
Thought disorders are when the person jumps from one subject to another for no logical reason.
Some negative symptoms i.e. these are symptoms which are normally present in a healthy individual, but are absent in a schizophrenic patient. E.g. absence of facial expressions, lack of motivation etc.
Cognitive symptoms affect the individual s thought process. They can be positive or negative based on their expression. E.g. poor  executive functioning  which deals with the ability to understand information and make decisions using them, finding it difficult to focus etc.
Although both Autsim spectrum disorder and schizophrenia are interlinked in their causes and neurological background, the symptoms for each disorder are different. 
Consult your physician if you happen to observe any of these symptoms in your loved ones.

Autism & Schizophrenia - What Is The Difference?

Your mother has often yelled at you for playing video games for long hours, but obviously you haven t paid heed to it. Such is the obsession with video games that they don t let you rest unless you have championed all the levels in the virtual interface. Here is the source of all problems. Studies have revealed that video games have a direct relation to neuropsychiatric problems. As a result, many health experts across the world consider video game as a kind of health abuse.

People who play action-oriented video games are at higher risks. The more you indulge in these kinds of games, the more they are going to affect the hippocampus section of your brain. It is that part of the brain which is considered to be the centre of your nervous system, memory and emotion. Reduced hippocampus volume may make person vulnerable to multiple neuropsychiatric complications. Let us see some of the signs, which may indicate the onset of certain complications arising from an over indulgence in these games.

1. You spend hours on the computer or related gaming devices and devote lesser hours for your family and friends

2. You get agitated when someone stops you midway through the game

3. You become socially isolated and show signs of occasional mood swings

4. You are unable to keep a track of time once you start playing

5. You repeatedly neglect your studies, resulting in a dip in performance at school

Why does this happen?

All of the above signs indicate that sooner or later you might develop neurological problems. When you spend an excessive number of hours on playing and navigating through the games, the  hippocampus  portion of your brain shows signs of decreased gray matter. As a result, the volume of the hippocampus shrinks, causing severe nerve related disorders such as schizophrenia, Alzheimer s disease, dementia, depression, and overall general stress.

One of the biggest reasons behind this is a lack of self-control. Most of the video games will encourage you to steal cars, run away after a theft and kill your enemies. Moreover, if you succeed, you are rewarded. This naturally unleashes a blatant urge for the gratification of all these awkward desires in your real life too. Hence, once you are encountered with the reality, you tend to show violent behavior.

Can Playing Video Games Cause Neurological Problems?

Headaches and migraines can vary drastically depending on their duration, specific symptoms and the person they are affecting. The more you know about your specific type of headache or migraine, the better prepared you will be to treat them and possibly even prevent them. The two types of migraine are- 

Migraine without aura: The majority of migraine sufferers have Migraine without Aura. 
Migraine with aura: Migraine with Aura refers to a range of neurological disturbances that occur before the headache begins, usually lasting about 20-60 minutes.
Symptoms of migraine vary and also depend on the type of migraine. A migraine has four stages: prodrome, aura, headache and postdrome. But it is not necessary that all the migraine sufferers experience all the four stages.

Prodrome: The signs of this begin to appear a day or two days before the headache starts. The signs include depression, constipation, food cravings, irritability, uncontrollable yawning, neck stiffness and hyperactivity.
Migraine Aura: Auras are a range of symptoms of the central nervous system. These might occur much before or during the migraine, but most people get a migraine without an aura. Auras usually begin gradually and increase in intensity. They last for an hour or even longer and are 

Visual: Seeing bright spots, various shapes, experiencing vision loss, and flashes of light
Sensory: Present in the form of touch sensations like feeling of pins and needles in the arms and legs
Motor: Usually related with the movement problems like the limb weakness
Verbal: It is related with the speech problems
Headache: In case of a migraine attack one might experience:

Pain on both sides or one side of the head
Pain is throbbing in nature
Vomiting and nausea
Sensitivity to smells, sound and light
Vision is blurred
Fainting and lightheadedness
Postdrome: This is the final phase of the migraine. During this phase one might feel fatigued, though some people feel euphoric.

Red flags that the patient may be having underlying serious disorder not migraine

Onset of headaches >50 years 
Thunderclap headache - subarachnoid haemorrhage 
Neurological symptoms or signs 
Meningism 
Immunosuppression or malignancy 
Red eye and haloes around lights - acute angle closure glaucoma 
Worsening symptoms 
Symptoms of temporal arteritis
These patients require CT scan / MRI or CSF examination. Most Migraine patients do not need these tests. 

Diagnosis of Migraine: Usually migraines go undiagnosed and thus are untreated. In case you experience the symptoms regularly then talk to the doctor, who evaluates the symptoms and can start a treatment. You can also be referred to a neurologist who is trained to treat the migraines and other conditions. During the appointment the neurologist usually asks about the family history of headaches and migraines along with your symptoms and medical history.

The doctor might advise for some tests like:

Blood Tests: These reveal problems with the blood vessel like an infection in the spinal cord and brain.
CT scan: Used to diagnose the infections, tumors, brain damage, and bleeding that cause the migraines.
MRI: This helps to diagnose the tumors bleeding infections, neurological conditions, and strokes.
Lumbar Puncture: For analyzing infections and neurological damages. In lumbar puncture a thin needle is inserted between the two vertebrae to remove a sample of the cerebrospinal fluid for analysis.
Treatments

Migraine treatments can help stop symptoms and prevent future attacks.

Many medications have been designed to treat migraines. Some drugs often used to treat other conditions also may help relieve or prevent migraines. Medications used to combat migraines fall into two broad categories:

Pain-relieving medications. Also known as acute or abortive treatment, these types of drugs are taken during migraine attacks and are designed to stop symptoms.
Preventive medications. These types of drugs are taken regularly, often on a daily basis, to reduce the severity or frequency of migraines.
Your treatment strategy depends on the frequency and severity of your headaches, the degree of disability your headaches cause, and your other medical conditions.

Some medications aren't recommended if you're pregnant or breast-feeding. Some medications aren't given to children. Your doctor can help find the right medication for you.

Migraine - Identifying the Early Signs!

Dementia refers to the progressive loss of memory in a human being. It does not refer to any particular disease. It is rather a cumulative representation of symptoms which signify that the person is losing his or her memory. Dementia occurs in seven stages. Read on to read more about them:

In the first stage, there is no cognitive decline and the person is mentally sound. There is no memory loss as well.
In the second stage, there is a very mild cognitive decline leading to normal forgetfulness that is often associated with progressing age.
In the third stage, there is a mild cognitive decline. The person has an increased forgetfulness and may find it difficult to concentrate on things.
In the fourth stage, there is moderate cognitive decline and the person starts forgetting even the most recent events. They cannot even travel alone or manage their own finances.
In the fifth stage, there is moderately severe cognitive decline. The person going through this stage often requires help even with their daily activities. People tend to forget even the most common things like phone and email passwords.
In the sixth stage, there is severe cognitive decline. This stage is also called middle dementia and there is prominent memory loss. People cannot even count from 1 to 10. Their speech becomes slurry. They also start having delusions.
In the seventh stage, there is very severe cognitive decline. This stage is also called late dementia. The psychomotor skills are also lost at this stage and the person may not even be able to walk properly.
Some of the early signs of dementia are listed below:

In the initial days of dementia, the person usually tends to get confused when it comes to choosing the right words. This makes them take much longer time to conclude their speech.
There might also be a change in the mood of the person.
Depression is also one of the early signs.

The person will have a tendency to forget even the most recent events that took place in his or her life. This means that they might remember what happened ten years before but they might not remember what they did in the morning.
Early signs also include failure to sense directions. People often tend to forget their addresses and the landmarks and thus become lost when they travel alone.
Confusion is also one of the common signs and this is directly correlated to the loss of memory because when a person cannot remember familiar faces, it leads to a lot of confusion within his own mind.
So, if you suspect that someone in your house is suffering from dementia, then you must look out for these early signs and seek medical help immediately. Early treatment can keep the condition from worsening.

Dementia - Stages and Early Signs!

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