Post-Transplant Lymphoprolipherative Disorder (PTLD) is a condition or a reaction that happens post your liver transplantation or any kind of organ transplantation. There is a rapid increase in the immune cells or more precisely, the lymphoid cells in the body. These cells start increasing without any control. The seriousness of this growth can be harmless but sometimes, it can develop into lymph node cancer as well.

The major reason behind PTLD is the anti-rejection medicines that are taken by the patient to avoid rejection and attack by the immune system.

Types of Post-Transplant Lymphoprolipherative Disorder (PTLD)

Early lesions: This will go away by itself, if the dose of anti-rejection medicine is reduced.
Polymorphic PTLD: This is a mixture of different kinds of lymphoid cells.
Monomorphic PTLD: This is the most common type of PTLD found in many people who have undergone a liver transplantation. This has just one type of lymphoid cell.
Hodgkin Lymphoma: This is a very rare kind of PTLD.
Diagnosis of Post-Transplant Lymphoprolipherative Disorder (PTLD)

Small and painless lump under the armpit, groin, or neck area
Night sweats
High fever
Excessive weight loss
Low appetite
Unwell feeling
Usually, it is not at all easy to diagnose PTLD. The lump may grow so deep inside the body that it can be hard to see or feel it from outside. Apart from the lump, others are general symptoms and they can be a reason for any kind of infection in the body post transplantation. It can be a reaction to any new medicine taken by you or a reaction to rejection. Early diagnosis can help you in increasing the chances of a successful treatment. A biopsy is also a good way to detect PTLD, where a small piece of the liver is taken and tested under a microscope to detect PTLD.

Management of Post-Transplant Lymphoprolipherative Disorder (PTLD)
Your liver transplant surgeon is going to work closely with the lymphoma doctor in order to provide the best treatment for you. For early lesions or Polymorphic PTLD, reduction of the anti-rejection dose can give you better results. Your immune system will restore back and will destroy all the abnormal cells in the body. But it has to be done slowly so that it does not cause organ rejection again. If reduction of anti-rejection medicine is not possible or if reduction causes any kind of harm, then other treatment methods like antibody medicine such as Rituximab, or chemotherapy regimen or radiotherapy may be used.

Post-Transplant Lymphoproliferative Disorder (PTLD) - How To Diagnose It Correctly?

Conventional medicine treats pain with the help of medications; by either blocking the transmission of pain signals in the body or by correcting the underlying problems caused by the pain in the first place. However, traditional and alternative forms of medicine such as acupuncture manage pain issues within the body through the means of redirecting disrupted energy flows. One of the very few forms of alternative treatments used in conjunction with conventional treatments, acupuncture is seen as a mercurial rise in popularity in the past few decades.


What is acupuncture?
Acupuncture dates back to ancient China, about 2500 years ago. It has been widely practiced there for a number of millennia, not only pain relief, but also for treating many ailments. Acupuncture isn t just considered a form of therapy, but a holistic form of medicine. Acupuncture works on the principle of the flow of energy within the body, also known as  Qi , in traditional Chinese medicine. Acupuncture strives to correct the disruptions in  Qi  that may cause pain by manipulating over 2000 of the specific pressure points within the body with the help of specially created needles.


Where is acupuncture effective?
Acupuncture is very effective in treating a host of ailments, especially in relieving the associated pain. Some of the areas where acupuncture has proven its effectiveness are:
1. Treating nausea and vomiting caused due to chemotherapy treatment for cancer patients
2.  Very useful in treating post-operative pain caused due to dental procedures
3.  Rehabilitating patients who have suffered strokes
4.  Fibromyalgia (musculo-skeletal pain with fatigue accompanied by sleep and memory issues) 
5.  Effective in combating withdrawal symptoms caused due to addiction
6.  Pain from menstrual cramps
7.  Tennis elbow
8.  Osteoarthritis (a type of arthritis caused due to the erosion of tissues present at the ends of one s bones)
9.  Pain of the lower vertebrae within the spinal column
10. Asthma


How does acupuncture work within the body?
According to modern medicine, the specific pressure points utilized by acupuncture within the body help in releasing chemicals that can block or at least reduce pain. It encourages the flow of chemicals from the brain, which act as nerve and pain blockers. It also helps stimulate the muscles and nerve endings, which can lessen inflammation and thus help in reducing pain.

Acupuncture - Why Should You Use it to Combat Pain?

Burn surgery is very common these days. Burn surgery is usually done on people who suffer from major burns. Reconstructive burn surgery is usually required in the last stages when the initial burns have healed to a certain extent. Usually reconstructive burn surgeries are done on patients who have suffered from huge accidents and have burnt their face, neck and hands to a great extent. Patients requiring this surgery usually become unrecognizable after an accident.

When is reconstructive burn surgery recommended?

If you have been involved in a household accident and the scars have not healed completely. Surgery might not totally heal the face, but it can improve your basic functions like breathing, smelling, seeing or tasting (if most of your senses are burnt and disfigured).
Reconstructive burn surgery is also very useful for acid attack victims. Sometimes, burns are not only caused by fire, but it is also caused by chemicals and acidic substances which are worse and can completely burn and disfigure your face. When hydrochloric acid, nitric acid and sulfuric acid come in contact with your skin it seeps into the skin and burns off your nose, cartilage and sometimes even causes blindness. It disfigures your face completely, reconstructive burn surgery can do miracles, though it cannot bring back your previous features and skin texture, but it does make you look more recognizable.
After a burn, facial scarring occurs which leads to the loss of eyelids, hair, nose and lips. In this case burn surgery is required.
How to take care of yourself after a burn surgery?

Regular stretching should be done, especially if the areas of your burn include your hands, legs, joints, etc. Do as much as activities as possible like getting dressed and grooming yourself. It will also make you more self-reliant and give you confidence.
Depression is very common after a burn surgery. A reconstructive burn surgery will not magically make you look the way you used to. A lot of sittings is required and remember, appearance and looks do not matter much. The wounds will fade away with time.
Itching is also very common after a burn surgery. If this problem persists, you should consult your doctor for a moisturizer.
Avoid sun exposure. Don t go out in the sun, because the U.V rays are extremely harmful and can singe your already sensitive skin; you can also get skin cancer.
Custom pressure garments should be worn to protect your skin.

Reconstructive Burn Surgery - How Can You Take Care Of It?

Surrogacy is a boon for couples who cannot conceive naturally or give birth to a child. Surrogacy is a process in which a woman's unfertilized eggs are implanted into the uterus of another woman who is called the surrogate mother. The egg is fertilized in the surrogate mother's uterus with the biological father's sperm. The surrogate mother lets the child develop in her womb and gives birth. Although, there are various medical treatments available, but not all of them have a high success rate.

The two primary methods of surrogacy are:
1. Traditional surrogacy: In this process, the surrogate mother is artificially inseminated with the sperm, which belongs to the biological father of the baby. The sperm gets implanted into the surrogate mother's uterus and the child develops in her womb.

2. Gestational surrogacy: For women who want to have a biological child in spite of being incapable of pregnancy, the gestational surrogacy method is used. During the process, in-vitro fertilization is undertaken and the eggs from the woman who wants to become a biological mother are harvested. The eggs, along with the sperm from the biological father are implanted into the uterus of a surrogate mother, who will carry the embryo and will give birth to the child.

Process involved in surrogacy
Here are the several processes and procedures, which need to be undertaken, after you have chosen a surrogate mother for carrying your child.

1. Medical testing: After a surrogate mother is chosen, the woman goes through several health checkups, medical and psychological tests to ensure that she gives birth to a healthy child.

2. Legal agreements: There are several legal considerations that have to be addressed for a surrogacy. All the legal requirements regarding the surrogacy should be written down. Some issues include both the surrogate mother and the biological parents. A financial contract must be presented as well, which will reimburse the medical expenses and requirements of the surrogate mother.

3. Medical process: The medical processes required for surrogacy include in-vitro fertilization and the transfer of the eggs, which are done in a clinic under the supervision of a reproductive endocrinologist. The eggs are transferred to the uterus of the surrogate, where fertilization takes place after combining it with the sperms of the biological father.

4. Pregnancy and birth: After successful fertilization, the surrogate mother gets pregnant. Proper care and precautions should be taken by her to ensure a successful birth. Finally, the surrogate mother gives birth to a child, who belongs to the biological parents.

This method of having a child has become very popular in the recent times. It is a great blessing for people who cannot conceive due to medical conditions or otherwise.

All You Need to Know About the Surrogacy Process

Unani is an ancient medical practice of the Middle East that people sometimes use to try to help alleviate conditions of psoriasis. It involves incorporating a special diet, use of herbal compounds and other additional supportive medical practices.

What is Psoriasis?
It is a common immune-mediated skin disease that is characterized by chronic and inflammatory scaly deposits on the skin called plaques. The dry flakes and skin scale deposits occur due to rapid build-up of skin cells. It has a substantial impact on the quality of life with reported impairment in physical and mental functioning.

Causes and symptoms of psoriasis
Heredity is a crucial factor when it comes to psoriasis. There is no definite cause of this skin condition, but consuming opposite foods, trauma on the skin like bruises, cuts, skin irritants, excessive smoking/drinking and mental stress can be some reasons causing it.

Here are some common symptoms of psoriasis:
  Silvery scales on skin
  Itchy and burning skin
  Pus-filled skin bumps
  Dry skin patches and skin redness
  Blisters
  Bleeding patches in skin
  Restricted joint motion
  Inflammation and pain in skin

The Unani view
There are several topical drugs, phototherapy and systemic medications available for psoriasis. However, according to studies, almost 50% of the patients were dissatisfied with their treatment. In the absence of satisfactory cure in modern medicine, the traditional system of Unani medicine is highly beneficial in treating Psoriasis. According to the Unani view, psoriasis occurs due to burnt melancholic humour that has an irritant nature. As a result, it destroys the skin and produces intense itching, roughness and scaling. The unique formulations of Unani aims to eradicate the skin disorder.

How can Unani help treat psoriasis?
Under the banner of the Unani system of medicine, physicians emphasize to apply emollient over the affected part in the form of ointment (Margham) or oil (Rogham). In addition to this, they also advise avoiding sweet or sour items in the diet. Herbal formulations and natural ingredients are used in these topical applications. When applied to the skin lesions over a prescribed course of time, it eases the skin and gets rid of psoriasis.

Risk and safety considerations
There are several studies undertaken to prove the effectiveness of Unani medications to treat Psoriasis, most of which are positive. The Unani medicines have not shown much side effects and can be taken for a prolonged period of time to yield positive results.

Unani medicine has been proven to have a positive effect on the PASI score of the patients, which assesses the severity of psoriasis. A proper diagnosis at an early stage followed by the appropriate treatment under Unani medicine yields remarkable results.

Effective Unani Medicine for Psoriasis Treatment 

An event or an accident that leaves us overwhelmed can lead to post traumatic stress disorder, also known as ptsd. A particularly stressful situation or event that has created terror or been overly dramatic or dangerous can lead to stress and anxiety long after the individual has physically come out of the situation. This kind of a traumatic condition is usually what characterises ptsd. This condition is something that is persistent, and can linger on for a long time, calling for medical supervision and care. Here's a list of things you need to know about ptsd.


	Duration: post traumatic stress disorder usually lasts up to six months. Yet, there are cases where it lingers on and requires treatment for some particular types of symptoms or behavioural changes. Usually, the patient's behaviour is a result of one or more of the symptoms discussed below.
	Re-experiencing symptoms: these symptoms include flashbacks and life like re-imagination in the form of dreams and nightmares. In many cases, the patient may remember and re-experience the entire scene or series of events that have led to the trauma in the first place. This can be triggered by a memory or association with words, events and other such things that have to do with the memory of the traumatic episode.
	Avoidance symptoms: a traumatised patient may go out of his or her way to avoid things that are remotely close to the traumatic incident. They may fear a reoccurrence or a reminder of the event and may avoid addressing the trauma altogether. Patients suffering from this symptom may have created a mental block, and may not be able to remember the exact details of the event. They may also feel emotions like fear, guilt, depression and even worry, over the past incident which led to the trauma in the first place.&nbsp;
	Arousal symptoms: arousal or reactivity symptoms may trigger the same reactions that the person showed during the traumatic experience. These may include being on edge constantly in anticipation of a reoccurrence, or even getting startled by the slightest thing since the mind is already occupied with thoughts of the event, constantly. Anger and emotional outbursts may also be caused due to these symptoms.
	Mood symptoms: mood swings are the most common outcome of these symptoms. The patient may experience a complete lack of enthusiasm and drive to indulge in activities like hobbies and socialising. Also, the patient may end up harbouring feelings of negativity towards family, friends and strangers, besides going through phases of guilt and self blame for the occurrence of the traumatic event.


Ptsd can be a debilitating disorder in the emotional sense, and should be treated by a psychiatrist in case it lingers on for more than six months.


All About Post Traumatic Stress Disorder

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