Thalassemia is a genetic (which is passed from parents to children through genes) blood disorder. People with Thalassemia disease are not able to make enough hemoglobin, which causes severe anemia. Hemoglobin is found in red blood cells and carries oxygen to all parts of the body. When there is not enough hemoglobin in the red blood cells, oxygen cannot get to all parts of the body. Organs then become starved for oxygen and are unable to function properly.

Symptoms

The symptoms depend on the type of thalassemia:

Thalassemia Minor: Thalassemia minor usually doesn t cause any symptoms. If it does, it causes minor anemia.
Beta-thalassemia: Beta-thalassemia comes in two serious types, which are thalassemia major, or Cooley s anemia, and thalassemia intermedia. The symptoms of thalassemia major generally appear before a child s second birthday. The severe anemia related to this condition can be life-threatening. Other signs and symptoms include:
fussiness
paleness
frequent infections
a poor appetite
failure to thrive
jaundice, which is a yellowing of the skin or the whites of the eyes
enlarged organs
This form of thalassemia is usually so severe that it requires regular blood transfusions.

Alpha-thalassemia: Alpha-thalassemia also has two serious types, which are hemoglobin H disease and hydrops fetalis. Hemoglobin H disease can cause bone issues. The cheeks, forehead, and jaw may all overgrow. Hemoglobin H disease can cause:
jaundice, which is a yellowing of the skin or the whites of the eyes
an extremely enlarged spleen
malnourishment
Hydrops fetalis is an extremely severe form of thalassemia. It occurs before birth. Most individuals with this condition are either stillborn or die shortly after being born.

Thalassemia - Symptoms Based on Types of Thalassemia 

Blood pressure is one of the vital life signs in medicine, which, along with other vitals is widely used to assess the overall health of the patient. High blood pressure is very dangerous as normally it has no symptoms or signs and can fluctuate almost instantly. But, it could be managed. High blood pressure is said to be of higher than 120 (systolic) and 80 (diastolic).

A nap in a day might help in lowering blood pressure. According to certain research findings, people who sleep in the daytime had regular blood pressure as compared to people who do not sleep or do not have a short nap. Napping can effectively help lowering blood pressure. It helps the blood to control stress hormones and also helps the nervous system to keep a person healthy.

Daytime napping surely helps in boosting energy levels and efficiency throughout the day. Blood pressure increases after a nap caused by the body s normal circadian rhythm (for influencing and regulating sleep-wake pattern for a healthy cycle in a day). At the time of the morning, the body releases hormones such as noradrenaline and adrenaline. If the blood pressure increases too high, it could cause harmful effects. Blood pressure is usually lower at night while a person is sleeping. The blood pressure begins to increase a few hours before a person wakes up. The blood pressure continues to increase during the day, normally extreme in the mid of the afternoon. The blood pressure starts dropping again in the evening and late afternoon. Sleep helps the blood to regulate stress hormones.

Napping, since it helps in lowering blood pressure, definitely helps in reducing the risk of Sleeping for about seven to eight hours in the night might play a vital role in the prevention of high blood pressure. New research suggests that an afternoon nap is as productive as consuming a pill for lowering the blood pressure. Scientists have found that the people who take a midday nap are more likely to drop their blood pressure as compared to adults who don t take a midday nap and stay awake. Napping, since it helps in lowering blood pressure, definitely helps in reducing the risk of cardiovascular events like a stroke or a heart attack. It is as effective as other lifestyle changes, according to credible researches in medicine. It is interesting to note that napping, even when it reduces the blood pressure by 2 mm Hg only, reduces the risk of cardiovascular events by 10%.

Napping is a sort of shortcut and an effective method for lowering the blood pressure and could also be easily adopted and does not cost anything. Short midday sleep is important for our well-being. And, we can utilize this simple information very effectively for its potential health-related benefits simply by managing our daily schedule.

Napping & Low Blood Pressure - How Can Former Help Latter?

Cyclic vomiting syndrome (cvs) is characterized by periodic bouts of nausea and vomiting that happens at cyclical intervals. It affects all ages, but is more common in children. The condition is quite stereotypical in that there are paroxysms or bouts of vomiting that is recurrent and follows days of normal health.

Causes: there is no definite reason identified, but it is said to have a strong hereditary correlation. Studies have shown mitochondrial heteroplasmic (abnormal growth of mitochondria, which is a cellular component) to be one of the factors that can lead to cvs. The genetic correlation, however, is very difficult to establish, specifically because vomiting and nausea are common symptoms that occur with most conditions in children. And cvs is most commonly noted with conditions like infections and emotional excitement. Infection could be either tooth decay or sinusitis or anything else. Lack of sleep, anxiety, holidays, allergies, overeating, certain foods, menstruation - a host of factors have been shown to induce cvs. There is also a strong association with migraine and conditions that lead to excessive production of stress hormones.

Symptoms: the syndrome (a group of symptoms) usually has 4 phases:

1. Symptom-free interval phase: the child is completely normal in this phase, which happens in between bouts.

2. Prodromal phase: prodrome is an indication that a disease or a condition is about to happen. In cvs, this is usually nausea and abdominal pain that can last from a few minutes to a few hours. Treatment in this phase can curb the disease. However, there could be some children in whom this may not manifest and the child may directly start with vomiting.

3. Vomiting phase: repeated bouts of paroxysmal vomiting happen associated with nausea, exertion, fatigue, and drowsiness.

4. Recovery phase: as the nausea and vomiting begin to subside, which may take a couple of days, the child returns back to normal slowly. However, the lethargy and energy levels will take a couple of days to return to normal.

Treatment: treatment again depends on the severity and the phase at which it is being recognized. If a child has repetitive bouts, then the parent and the doctor would have identified a pattern to it.

1. If the causative agent has been identified, for instance, infection or migraine, then managing that takes care of the cvs also.

2. If identified during the prodromal phase, again it can be managed with suitable anti-emetic medications.

3. If identified after full onset, rest and sleep and medications to control nausea and vomiting are required. Adequate hydration with electrolyte replenishment and sedatives can provide additional support.
However, in most cases of childhood csv, the pattern will be identified and that helps in better management, both the child/parent and the podiatrist.

Cyclic Vomiting Syndrome in Children - Causes, Symptoms, Treatment

Manic depression, also known as bipolar disorder in recent days, is a major mood disorder characterized by hypomanic or manic episodes (deviation from one's usual mood along with abnormally high energy levels). Mania involves sleeplessness, along with psychosis, hallucinations, rage, grandiose delusions or paranoia. Mania or hypomania isn t usually harmful to the patient and they might exhibit increased capacity for work and creativity. Depressive episodes however, can be debilitating and often life threatening as the person becomes self-destructive and suicidal in many instances. 

The extent of mood swings can vary from extreme to very mild. They can occur progressively or suddenly and might last for few days to weeks. Patients affected by bipolar disorder may experience disturbances in thinking apart from depressive or manic episodes. Distortions of perception and impaired social functioning are also not uncommon. The cause of bipolar disorder is not fully understood like most mental health conditions and is often thought to be hereditary.

The extent of the seriousness of the bipolar symptoms varies from person to person. In some people, the disorder is not full blown and they don t exhibit all the symptoms. Others who aren t that lucky might have to be hospitalized multiple times in their lives as the symptoms creep into their work and personal life and make living a normal life a tough challenge. 

Psychotic symptoms such as disorganized thinking, hallucinations and delusions might make a person do things that demand the urgency of hospitalization to keep them safe from their suicidal impulses. These symptoms might need to be urgently addressed by a psychiatrist and with the help of medications, the person might be able to regain control of their lives.

The symptoms of bipolar disorder are many and can be mainly categorized into two (sometimes overlapping) categories of mania or hypomania and depression:

Manic symptoms include: 

Grandiose delusions (delusion of grandeur) 
Racing thoughts which are often disconnected
Sense of euphoria or false elation
Irritability without cause
Hampered social functioning
Increased sexual inclination and risky sexual behavior
Hyperactivity
Increase in talking volume or speed
Impaired judgment
Reduced sleep requirements owing to extra energy levels
Increased productivity and creativity
Depressive symptoms include:

Abnormal eating patterns like over or under-eating to the extent of severe medical complications accompanied by drastic changes in weight
Difficulty in concentration, making decisions and remembering
Lack of energy or fatigue 
Contemplating about death for prolonged periods of time and suicidal behavior
Oversleeping, insomnia or early awakening
Persistent pessimism 
Irritability and restlessness
Feeling of hopeless and negative attitude
Mood stabilizers, such as lithium are commonly employed to treat bipolar disorder. Anti convulsants, benzodiazepines and anti psychotics can also be used in the treatment. Along with medications, support from family and friends is of the utmost importance as they need to help provide all the support required in making the person functional and healthy.

Manic Depressive Disorder - 11 Signs to Help You Spot it 

Has your little child hit his head against a hard surface after falling from a height? Has he lost consciousness, appears dazed or is crying uncontrollably? Such conditions signify that your child has a concussion. A concussion refers to a brain injury, which occurs due to a blow to the head. It may result from a fall, a car crash or due to a sports injury. Toddlers are more prone to head injuries because of their curiosity and poor motor nerve skills. Most such injuries are harmless, but sometimes a fatal blow to the head might lead to severe conditions. Immediate treatment and care are essential in such situations.

Diagnosis:

Several medical tests and examinations must be carried out for the diagnosis of a concussion. They include the following:

    Neurological exam is carried out to determine the functioning of your child's brain.
    X ray of the child's head has to be carried out in order to check for other injuries like fractures.
    A CT scan can be performed where the child has to intake a dye before having an X ray done. This will provide better pictures.
    An MRI scan can be performed for diagnosis as well where powerful magnets, and a computer are used to take pictures of the child's head and blood vessels.

Treatment and Management of a Concussion:

Usually, no special treatment is required to treat concussion in a toddler. A doctor may have to be consulted, and the child may have to spend some time in the hospital. Several medicines are prescribed by the doctor for the child in order to provide pain relief.
There are several ways which you need to follow in order to manage the symptoms of a concussion in your child. They are as follows:

    Ice: Ice provides relief from pain and reduces swelling in head injuries. Ice also helps in preventing tissue damage. You should use an ice pack, cover it with a towel and apply it to the injured area on your child's head.
    Rest: Right after a concussion, your child must be put to rest in bed for at least twenty-four hours. Eventually, he can get back to being active as he feels better.
    Restriction on activities: Your child should not take part in sports or any activity, which may result in a fatal blow to his head. Having another concussion before the brain recovers from the previous one can be fatal.

In cases where your child experiences nausea and vomiting, intense headaches and passes out, you need to rush him to the hospital. You must consult a doctor when the symptoms keep on worsening and continue for several weeks. Without a proper treatment, your child may develop post concussion syndromes, such as headaches, depression or short-term memory loss.

How to Handle Concussion in Toddlers?

The testes are an important part of the human reproductive system and are susceptible to injuries as well as internal problems. One such problem which is known to afflict younger men mostly from the age of 12 to 16 is testicular torsion. It can affect older men, but is commonly seen in the aforementioned age group. It is a painful condition that will require medical attention and if left untreated might even result in removal of the organ in rare cases.

What is testicular torsion?
There are many intricate functions performed by multiple blood vessels within the scrotum that supply the testes with blood. However, one of the testicles might rotate and thus end up twisting the spermatic cord. This cord brings blood to the testicles and if twisted, will reduce the flow of blood significantly. Thus the scrotum may swell up and also become quite painful.

Symptoms of testicular torsion
1. Significant swelling of the scrotum
2. Mild to extreme pain in the scrotum.
3. Abdominal pain, especially in the lower abdomen
4. Unusually positioned testicle such as one significantly higher, behind, or in front of the other one.
5. Fever
6. Feeling nauseated and may be accompanied by vomiting
7. Pain during urination
8. Inability to sleep or waking up in the middle of the night due to the constant pain

What causes testicular torsion?
In certain cases, testicular torsion may occur and then go away on its own when the testicle rotates, resulting in the untwisting of the spermatic cord (which is also known as de-torsion). However, it is still advisable to visit a doctor and ascertain what caused it so that the risk factor could be eliminated as torsion and de-torsion could keep happening frequently. Some of the common causes for testicular torsion are mentioned below.

Hereditary factors: If someone in your family has suffered from this condition, you could be susceptible to it.
Injuries: If you receive minor trauma such as the one during playing any kind of contact sports, outdoor activities or even while doing house work, it can be a reason of this condition as well.
Activities that put stress on the scrotum: Heavy exercising or running in an unbalanced or improper manner can cause torsion as well.
Improper sleeping positions: This can also cause torsion and is a common cause behind frequent torsion and de-torsion.
Other factors: These factors can include excessively cold temperatures wherein the scrotum contracts rapidly and prolonged contraction can cause torsion. Even the rapid growth of the scrotum during the adolescent years after puberty may cause this.

Torsion of Testes - 5 Common Causes Behind It

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