Alzheimer's disease is a neurological problem that is characterised by a cognitive decline and memory loss. It is a type of neurodegenerative dementia. The symptoms of alzheimer's disease include not being able to absorb and retain new information, lack of reasoning and judging, not being able to take on complex tasks, impaired visuospatial abilities, problems in reading, writing and speech, among many others. If a person has at least two of these symptoms in a debilitating manner, then the diagnosis can be made in favour of alzheimer's disease. The main causes of alzheimer's are shrinkage of the brain size and death of the brain cells. The immune system is also said to trigger this neurodegenerative disease. Let us find out what medical science has found so far.

1. Connections: many a times, in alzheimer's disease, the memory and behaviour of the person changes because the brain is unable to make proper neural connections which can lead to memory loss of how a person behaved and the elements that formed the basis of the patient's cognition. Apparently, the immune system behaves in the same way within the brain and blocks the connection. This happens because there is constant communication between the brain and immune system along neurological lines, which is where the disease first emanates.

2. Inflammation: the brain is prone to inflammation or swelling that is not the normal kind. This inflammation happens as a result of the activation of the infection fighting neurotransmitters and the chemical changes that happen in the brain when an infection strikes. The inflammation usually happens in the plaques or clumps which the brain tries to protect. These clumps are made up of a protein called amyloid. The immune system is responsible for creating this inflammation in the brain of the patient.

3. Pattern recognition receptors: many of these receptors work in different manners and cooperate with each other to create a response in the brain. These prrs can be found in the brain plaques, and they develop the signs of danger which further fuels the inflammation in the brain as a matter of protection.

4. Activation of cells linked with the immune system: when the prrs begin to respond, it basically activates the immune system and the cells of the same. This is the basic reaction that causes the changes in brain which then leads to the attachment of the protein to the tissue that is diseased, in which case alzheimer's disease starts. The inflammation that we had spoken about earlier basically happens in the nervous tissue.

It is important to recognise and act on the initial signs of alzheimer's disease before it progresses beyond one's control.

Can the Immune System Trigger Alzheimer's Disease

The skin is an elastic organ (yes, it is an organ!), but only to a certain extent. It has a limit to which it can accommodate the underlying tissues. With the increase in bulk, for example, puberty, pregnancy, muscle mass building or surgical implants, the skin is made to stretch beyond its limits. What happens is this stretch causes the skin to stretch too, and these stretch marks or striae become an unpleasant thing that needs to be hidden. 

Dressing needs to be changed so that they are not showing. Dermatologists see a big demand for getting rid of these marks too. There have been conventional, time-tested methods which help in getting rid of these. However, with newer advancements in dermatology, the platelet rich plasma is being widely used for getting rid of these stretch marks.

Why stretch marks? 

In any of the scenarios above, the stretch marks appear because there is a lack of underlying supportive tissue when it is stretched out. There is a lack of collagen and connective tissue, causing stretch marks. These are most evident in fat collecting areas like breasts, abdomen, thighs, upper arms, etc.

What is platelet-rich plasma or PRP? 

The blood is composed of a liquid portion known as plasma, which contains three main types of cells i.e. white blood cells, red blood cells, and platelets. The white blood cells are the ones responsible for fighting infections. The red cells give blood its color and also are responsible for carrying nutrients to the various organs. The platelets are tiny fragments of cells which help in blood clotting. Platelets are also rich in what are called totipotent cells, which can grow into any type of cells. When the body is affected, due to injury, infection, trauma, etc., these get concentrated in the affected area and are produced in large numbers to help in the recovery of the particular affected area.

Technique: 

The area to be treated is isolated and prepared. Blood is centrifuged to remove other cells and obtain platelet rich plasma. This RPR is injected into the underlying layers of the skin. This induces the release of growth factors into the connective tissue space. Collagen is produced over a period of time, which causes the skin to become taut and lose the stretch marks. The injection can be repeated if required on the topmost layer. It can also be mixed with thrombin to form a gel, which is then used similarly. Using it both in the underlying and superficial layers helps in completely getting rid of the marks.

Studies have shown a reduction in both the depth and size of the stretch marks and some might require two to three repeat injections.


Stretch Marks - How PRP Therapy Can Help You?

Aging comes with many health problems including mild hearing loss. Usually, this mild hearing loss does not come alone. According to medical studies, adults, particularly males with hearing loss, mild or severe, are at a higher risk of developing Dementia and Alzheimer s disease. The risk increases as the hearing loss worsen. People with mild hearing loss are at twice the risk of developing dementia compared to people with normal hearing.

Dementia is a group of symptoms and diseases that affects the thinking, memory and social abilities that interfere with the daily functioning of an individual. However, memory loss alone does not mean that one has Dementia. Out of the many causes, Alzheimer s disease is usually the cause of Dementia. Alzheimer s disease is a progressive disease that affects the brain cells to degenerate and dies, destroying memory and other mental functions. 

How Hearing Loss Causes Alzheimer s?

According to medical studies, hearing loss causes several brain changes which increase the risk of developing Dementia. Hearing loss can lead to brain shrinkage, the process in which the section of the brain responsible for hearing becomes inactive. This condition leads to loss of tissues and alterations in the brain structure, developing as the first connection between hearing loss and Alzheimer s. Studies show that the brain of people shrinks more quickly who have hearing loss as compared to the brain of an individual with normal hearing. 

The second link created with an overwhelmed or overloaded brain. In hearing loss, the brain works overtime in understanding what others are saying. When the brain strains too much only for hearing every time and every day, it exhausts an individual s mental energy and snatches the brainpower required for other important mental functions, such as thinking, remembering and acting. This can further lead to Dementia, Alzheimer s and other mental disorders. 

Hearing Aids to prevent Dementia and Alzheimer s

According to various studies, hearing aids are not only helpful in improving one s hearing but they can also preserve an individual s mental and emotional health. Early diagnosis and treatment of a possible hearing loss help reduce risks later in life.

At times, the symptoms of undiagnosed hearing loss are mistaken with the symptoms of Alzheimer s. Hearing impairment makes it challenging for an individual to listen and respond to verbal signs. It increases the feeling of confusion, paranoia, and isolation. 

Hearing aids can relieve the symptoms of Alzheimer s. According to a study hearing aids slow down the rate of memory loss and improve an individual s quality of life.

Takeaway

Adults, especially males with hearing loss have a greater tendency of developing Dementia and Alzheimer s. Hearing loss causes brain to overwork leading to the loss of important mental functions. Hearing impairment can worsen the symptoms of Dementia and Alzheimer s. 

Hearing aids do help in improving the condition and symptoms of Alzheimer s and improve one s quality of life. A timely diagnosis can make a big difference.

Dementia And Alzheimer's Disease In Elderly - Could Hearing Loss A Reason?

A lot of things can be done to cope with the initial stages of dementia. A person goes through a wide range of emotions such as fear, denial, frustration, and anger, post the diagnosis. Here is a list of tips that will help a patient with dementia to cope better:

Physical health: For a dementia patient, it is very important to take care of one s health. A good diet along with regular exercise and adequate rest is a prerequisite to manage this disorder.
Regular check-ups: Regular medical check-ups with the doctor are necessary in this condition. Depression and other mental health problems should be discussed with a professional.
Quit alcohol: Alcohol might give momentary pleasure from the misery, but it has long-standing implications. It reacts with the medicine and creates additional health and memory-related complications.
Allocate time for difficult tasks: With time, it can become difficult to perform even the simplest of tasks. The patient should accordingly schedule the time to perform the tasks which may be difficult to carry out. Adequate breaks should be taken while performing a task to avoid getting fatigued.
Redefine work: If a patient is suffering from dementia is still working, it should be ensured that the work is more manageable from a desk. Planning an early retirement may be a good idea in order to cope with dementia.
Be organised: Keeping track of things can get difficult with time. It, therefore, makes sense to organise all belongings systematically. Putting labels on doors and drawers also help.
Continue pursuing your hobbies: Amidst the difficulty and the depression, it is a good idea to continue doing things that are fun. While such activities might require some assistance from the doctor and family members, this helps the patient to be cheerful and healthy.
Maintain notes: Since dementia is involved with forgetfulness, it makes sense to maintain a diary and keep records of phone numbers, people, appointments, etc.
Communication channel: Maintaining a direct communication channel with family, friends, and relatives is a good idea. Sharing feelings will go a long way in maintaining relations with loved ones.
Support group: Joining a dementia support group can be highly beneficial for the patient. It will not only give the patient company but also make sure that the patient gets a lot of useful information about the disorder. It also helps in keeping the morale up.
Getting ready for the future: Things need to be meticulously planned well in advance to ensure that when the disease progresses, the patient has enough people to look after him. Things such as medical arrangements, financial assets, and property details should be carefully handed over as per the patient's wish. This will ensure a smooth run of the patients  life when they can no longer take care of themselves.

Dementia - Easy Tips To Help You Cope With It!

Alzheimer s disease is a neurological, irreversible, progressive brain disorder. It is a chronic neurodegenerative dementia that causes the death of brain cells, causing memory loss and cognitive decline. It affects a person s thinking and behavior. The symptoms develop slowly and get worse as time passes.

Causes:
As it is a kind of dementia, Alzheimer s is caused by the death of brain cells. Over a course of time, brain cells die progressively and at the end, the tissue is left with fewer nerve cells and connections. As a result, the total brain size shrinks. Tiny inclusions called plaques and tangles can be seen in the postmortem. These cannot be seen or tested in a living Alzheimer s affected brain. These plaques are given the name  amyloid plaques  because they are found among the dying cells of the brain when a protein called beta-amyloid builds. The tangles stay in the neurons; they are formed from a protein called tau.

There are several reasons behind all this, some of which are listed below-

Anti-anxiety medications
Hitting on the head too many times
Regularly sleep-deprived
Loneliness
Diabetes in the brain
Old age
Genetic line
Down s syndrome
Cardiovascular diseases
Symptoms:
Alzheimer s disease damages the brain, so the clinical signs and symptoms begin to show very early. The symptoms are-

Memory loss
Agitation and mood swings
Poor judgment
The trouble with money calculations
Difficulty doing familiar tasks
Trouble in planning or solving a problem
Confusion with time and place
Difficulty in communicating
Loss of motivation
Inappropriate behavior
Aggressive personality
Childlike behavior
Preventing Alzheimer s disease:
Alzheimer s disease ultimately results in death. Even if there are treatments, they cannot fully cure it. So it s better to try to prevent it before it happens. Ways to prevent Alzheimer s disease are-

Eating more fruits and vegetables.
Eating berries every day.
Increasing omega-3 fatty acids.
Taking folic acid supplements.
Drinking grape juice or red wine with evening meal.
Doing the Mediterranean style diet.
Controlling the blood pressure.
Having strong social support.
Treatment of Alzheimer s disease:

Treatment of Alzheimer s disease is a long time process.
First of all, doctors perform a physical exam to check the overall neurological health. By this, they check muscle strength, reflexes, walking ability, sense of sight and hearing, coordination and balance.
Then comes the blood test to find the cause of confusion and memory loss by checking the thyroid disorder and vitamin deficiency.
Then they perform the neuropsychological test and check the mental status.
Then there are other tests, like MRI, CT, and PET.
After all this, drugs are given and a safe and supportive environment is created with proper exercise and nutrition.
Alzheimer s disease is undoubtedly the worst kind of disease. Hence, it is highly recommended to contact a doctor as soon as any symptom is noticed.

All About Alzheimer's Disease!

With age, most body organs begin to deteriorate in their function. This happens to the brain also, thereby reducing the overall speed of functioning of most organs. While slowing of bodily movement is visible, the internal organs functioning also slows down, which is not that obvious. Memory loss or dementia is one of the main manifestations of this degeneration of the brain.

Alzheimer s is the most common form of dementia, and the associated symptoms includes reduced reasoning abilities and cognitive defects. Though it is seen only in the elderly, not all elderly people will have Alzheimer s. The overall quality of life of the affected person is reduced with difficulty remembering things that were recently learned. It is a progressive disease and as it gets more severe, a full-time caretaker may be required.

Causes: The brain cells are affected by protein masses known as plaques and tangles. These hamper the way communication between the brain cells happens as well as affect nutrition from reaching all parts of the brain. This leads to shrinking of the brain, eventually leading to memory loss and other problems. There is also a strong genetic linkage, as most people with Alzheimer s have the lipoprotein A gene.

Symptoms: Though memory loss is the most common symptom, there are other symptoms:

Being confused about places, people, and times
Inability to find the right words during conversations
Regular objects are misplaced
Becoming irritable, (in someone who was not so previously)
Mood swings
Personality changes
Inability to organise thoughts
Not able to make the right decisions
Repetitive talks and actions
Forgetfulness (not something the person always does)
Difficulty with numbers (again, not something calculations
Difficulty managing everyday tasks and minor problems
Suspicion of others (like immediate family members and friends)
Risk factors: While age is definitely a risk factor, the fact that not all aged people develop Alzheimer s is to be borne in mind. Other risk factors include the history of stroke, high cholesterol, high blood pressure, diabetes, smoking, obesity, and poor lifestyle choices.

Diagnosis: While there is no definitive way to diagnose Alzheimer s, symptoms along with brain scans and neuropsychological function testing are useful ways to confirm the diagnosis.

Treatment: This is aimed at two things reducing the rate of disease progression and treat (or reverse) symptoms if possible.

Cholinesterase inhibitors improve cellular communication in the brain and also manage depression and agitation. Memantine is used to slow the pace of disease progression.
In people with the disease, small changes are useful to help them with the symptoms. These include keeping essential things like keys and wallet in the same place, keep a daily diary to help them remember things, keep pictures of friends and family within visible distance.

Alzheimer's - An Overview!

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