Cushing syndrome occurs due to prolonged exposure to high levels of cortisol hormone. The condition, often referred to as hypercortisolism, affects women   usually between ages 25 and 40   more than men. Nearly 80% of adults and about 47% of children are diagnosed with cushing syndrome.

The most common cause of cushing syndrome is an overproduction of the stress hormone   cortisol   by the adrenal glands. However, it can also result from overuse of steroid drugs.

If you have cushing syndrome, you are likely to notice symptoms like muscle weakness, weight gain, a buffalo lump, irregular periods, sleep disorders, high blood glucose and high blood pressure.

Recent research has claimed to establish a relation between cushing syndrome and high blood pressure   or what is called hypertension in medical terms.

The link between hypertension and cushing syndrome

Hypertension refers to high blood pressure that causes the force of blood to raise against the artery walls. A number of conditions can lead to hypertension, such as poor diet and lifestyle, an underlying health issue, stress, pregnancy and so on.

As your body encounters stress, the adrenal glands produce and release cortisol in the bloodstream. Studies show that producing excess stress hormone can create a host of pathological problems in the body, including hypertension.

Hypertension is a distinguishing feature of endogenous cushing syndrome. High blood pressure in cushing syndrome has a significant correlation with the duration of hypercortisolism and results from the interaction between various pathophysiological methods regulating peripheral vascular resistance, cardiac output, and plasma volume   all of which are elevated in this state.

How to treat the condition

Cushing syndrome is usually treatable and curable. You will be prescribed to stop using steroid drugs that are likely to increase cortisol levels. If the condition does not improve after treatment, you will have to look for ways to manage the symptoms, especially by monitoring your blood pressure. Team up with your doctor and ask for ways to de-stress yourself.

Relation Between Cushing Syndrome And Hypertension: Know More

A brain tumour is a life-threatening situation. Most of the symptoms of the brain tumour are alike, but not all tumours are malignant. The most common type of brain tumour is meningioma. You may even don t need surgery in this case as they are really not dangerous or life-threatening.

 

Here are some of the facts you should know about meningioma:

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Meningioma can develop in numerous locations

 

Cells in the meninges, the lining of the brain and spinal cord, give rise to these tumours. In fact, they are not brain tumours at all, because they are not caused by the altered brain cells. ;

However, they continue to grow inside your sull, indicating that you should now take immediate steps. Meningioma can produce brain tumour symptoms if it grows or creates swelling that presses against the brain or other tissues in the skull.

 

Meningioma symptoms vary depending on the size and location of the tumour

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Meningioma can cause vision-related issues, headaches or seizures which are all common signs of a brain tumour. A headache, even a strong one, is seldom an indication of meningioma or any other type of brain tumour on its own. 

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Other tumour sites can influence your sense of smell, vision, hearing and even the pituitary gland s function.

 

Meningioma diagnosis usually happens when the doctor is looking for some else

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The discovery of a tumour on a ct scan or mri while investigating the patient for another cause, such as a head injury or another neurological condition, is called an accidental diagnosis. When a doctor identifies a meningioma, you will undergo additional testing to determine how the tumour will behave. A neurosurgeon will decide whether to remove the tumour or just monitor it to see whether it grows based on these findings. 

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Majority of meningioma does not spread

 

Being diagnosed with meningioma, especially a large one, might be shocking, but these tumours are usually non-dangerous. Tumour cells are unlikely to spread to other sections of the body as a result of this. ;

Meningiomas, on the other hand, can grow silently for years without creating any difficulties and they can grow to be enormous.

 

Things You Should Know About Most Common Brain Tumours

Environmental factors play a quintessential role in affecting our health. Fresh air, fresh food and fresh water, not only strengthen our body and mind but also make our life worth living. Contrary to this bad environment hampers the quality of life. This is the main reason why people from hill stations or the countryside seem to be healthier than those living in polluted urban cities. Following are the environmental factors that affect your health:

Polluted air

The health effects of polluted air are several. Not many people know that one-third of the deaths are caused because of strokes, lung cancer and heart failure. Air pollution is the chief reason behind these chronic ailments. The other life-threatening diseases caused by polluted air is- asthma or bronchitis. Smoke from machines, vehicles outside, and stoves, the burning of fuels inside can cause breathing problems and wheezing. 

Dirty environment

A dirty environment often leads to the breeding of insects and bacteria that become carriers of life-threatening diseases such as dengue, typhoid, diphtheria, malaria, and so on. Most of the diseases mentioned here are caused by mosquitoes that thrive on stagnant water.

Toxic food ;

The environmental quality of a region has a direct impact on the food produced in that area. Both vegetarian and non-vegetarian food faces the danger of becoming toxic if the environment it is being grown in is polluted. For eg- chemical wastes that are often dumped in water bodies cause the seafood in that area to become highly toxic.

Chemical pollutants

Cancer nowadays is becoming a household disease. The major reason behind this is that technological development has brought new categories of pollutants. Many of these contain chemicals and compounds that are carcinogenic in nature. This ultimately leads to the development of cancer in most people. 

Climate change and natural calamities

Change in climate disrupts the functioning of nature in many ways that further impact the health of humans. These changes include- the natural temperature of the planet, heavy rainfalls and sandstorms. The numerous impacts of climate may result in a high risk of nervous and respiratory diseases. ;

Hence protecting the environment is extremely important for the life of a human being. The change will come after taking small steps. Numerous small steps can really make a difference. 

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Environmental Factors That Affect Health

We often forget to take note of things that could cause a spike in blood pressure levels like sleep apnea, ;high sugar intake, among others.

What Are The Things That Could Spike Your Blood Pressure Levels?

Type 1 diabetes occurs when your pancreas is unable to produce enough insulin to keep the blood sugar ;levels under control. The condition, if not managed properly, can lead to related health disorders and complications, both long-term and short-term.

Health problems arising from type 1 diabetes

Type 1 diabetes can have severe effects on your eyes, kidney, nervous system, and heart health. The most common ailments associated with type 1 diabetes may include the following-

1. Diabetic retinopathy

Diabetic retinopathy is a disease of the eyes, which occurs when the blood vessels in the retina (tissue present at the back of your eyes) are damaged. The walls of the retina gradually weaken from increasing blood pressure and blood sugar levels, and this leads to leakage of blood or fluid into the nearby tissues.

Early symptoms of diabetic retinopathy include-


	
	Blurred vision
	
	
	Floaters
	
	
	Difficulty perceiving colors
	


2. ;Diabetic neuropathy

Diabetic neuropathy unfolds when the nerves are damaged due to type 1 diabetes. The condition mostly affects your feet and legs. Reduced blood circulation due to high blood glucose impedes normal wound healing in the extremities, hence, even a minor bruise ;can develop into a permanent injury.

Symptoms of diabetic neuropathy are-


	
	Numbness
	
	
	Reduced sensation
	
	
	Severe, debilitating pain in the extremities
	


3. Diabetic nephropathy

Also known as ;diabetic kidney disease, the condition is a slow deterioration of the kidney and its ability to function properly. In severe cases, where the levels of blood glucose are extremely high due to type 1 diabetes, diabetic nephropathy can ultimately result in kidney failure ;or end-stage renal disease (esrd).

The following are the symptoms of diabetic nephropathy-


	
	Dark urine
	
	
	Swollen ankles, feet, eyes, or hands
	
	
	Shortness of breath
	


4. Cardiovascular diseases

Cardiovascular diseases refer to a range of heart conditions including blood clots and diseased blood vessels. High blood glucose levels resulting from type 1 diabetes can contribute to the deposition of fat in the walls of the blood vessel. Over time, this may restrict the flow of blood and put you at risk of cardiovascular disorders such as coronary artery disease, stroke, or even ;heart attack.

Symptoms of cardiovascular diseases widely vary, ranging from palpitations ;to chest pain. Sometimes, such a condition may not exhibit any symptoms at all.

Type 1 diabetes complications are related to poor management of blood glucose. The best way to monitor the condition and control the symptoms is to get in touch with your doctor. A specialist in this field can prescribe the correct treatment and help prevent the onset the related health disorders.

Complications Associated With Type 1 Diabetes

People suffering from sickle cell disease (scd) usually start showing symptoms very early. They can appear to show up even during the first year of life. Symptoms of a sickle cell vary from one person to another and can be mild to serious depending on the condition.

 

Sickle cell disease is a health condition that worsens with time. Despite the absence of any full-proof solution, some treatments prevent further complications. These treatments can help patients receive aid for a lifetime. Simply said, sickle cell diseases can be managed medically.

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Treatment

Treatment in a sickle cell patient depends on the severity of the symptoms. Preventing complications and relieving pain is the primary aim of the diagnosis. They can range from medications to blood transfusions.

 

Concerns

Some of the concerns that need to be taken care of during the treatment of scd are-

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	Prevent painful scenarios
	


A painful episode or sickle cell crisis can be avoided by consuming sufficient fluids, wearing warm clothing, and staying away from sudden temperature changes.

 


	
	Avoid infections
	


Children with sickle cell anemia are made safe from infections by using penicillin. Adults with anemia might need to take penicillin all their lives. Doctors should ensure that all vaccinations in children and adults are periodically done to avoid any infections. However, during the covid-19 pandemic sickle cell patients should take extra care.

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Medications

While there can be numerous ways to manage sickle cell treatment, medications help in a significant way. Some of the prescribed medicines are-


	
	Hydroxyurea- it reduces the frequency of sickle crises. Pregnant women should stay away from this according to experts.
	
	
	Crizanlizumab- this drug injected into the patient can help reduce the sickle crises in adults and children over the age of 16.
	
	
	Voxelotor- it is an oral drug used in children over 12. It lowers the risk of anemia by improving blood flow.
	
	
	Pain-relievers- narcotics to prevent excessive pain can also be used during the treatment.
	


 

Surgical procedures


	
	Blood transfusion
	


It is used to prevent stroke and other related complications in patients. This can increase the number of red blood cells in the body that can help reduce the symptoms.

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	Stem cell transplant
	


It is also called a bone marrow transplant and is used to replace affected bone marrow with a healthy one. This procedure is carried out between matched donor and recipient. Although it is a known cure for sickle cell disease, various risks involved make it a less used practice.

 

Can Sickle Cell Be Cured?

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