In recent times, the advancement of medical science has substantially contributed in comprehending the Alzheimer s disease. Unfortunately, the number of individuals suffering from the disease is expected to rise in the next ten years which pose a threat to the allocation of health care resources and public health. Alzheimer s disease is thought to be a complex disease which influences a person s behavior as well as cognition through numerous mechanisms.

Can surgery be deemed as a treatment for Alzheimer s disease?
The surgery is a multicenter clinical trial which is making a new direction in clinical research. It is devised to halt or slow down the problems caused by the disease which gradually erases a lifetime of memories in elderly patients. Though there is no cure for Alzheimer s disease, it has been found that low-voltage electric charges delivered right at the brain. Only the symptomatic therapies for Alzheimer s disease are provided which do not have any effect on the evolution of the disease. The standard medical treatments for Alzheimer s disease include cholinesterase inhibitors along with a partial N-methyl D-aspartate antagonist. In most cases of mild to moderate symptoms of this disease, a combination of treatments is used according to the clinical history, age and condition of the patient.

Mental activity supporting cognition
Many patients having normal cognition or mild impairment have a fear that they may develop AD. Many experts are of the opinion that mentally challenging activities including brain teasers and crossword puzzles can be helpful in reducing the risks in such patients. Clinical trials are under the way for determining whether or not these types of activities have any substantial effect on halting the progression of AD.

Treating AD in its moderate to the severe stage
Numerous studies have shown that blockade of NMDA receptors by memantine can be used safely in combination with ChEls. This combination has been shown to delay the institutionalization in patients with Alzheimer s disease.

Treating secondary symptoms
A variety of behavioral as well as pharmacologic interventions can help in overcoming the clinical manifestations of the disease. These include anxiety, psychotic behavior, depression and agitation among others. The effectiveness of this disease can range from modest to excellent. No particular agent or dose of it can be unanimously accepted to be the sole treatment option for the wide range of clinical issues. Moreover, in the recent time, the FDA has not accepted any psychotropic agent for treating AD.

Along with these treatment options, there are behavioral interventions that can range from patient-centred approaches to caregiver training for helping manage the cognitive and behavioral manifestations of Alzheimer s disease. Last but not the least, it is very crucial to point out the significance of treatment in the early stages of AD in order to cure it better.

Alzheimer's Disease - Can Surgery Help You Treat It?

Chromosomal abnormality happens when a cell has too many or too few chromosomes. The most common form of chromosomal anomaly is Down s syndrome. If a parent has a chromosomal anomaly, she/he will pass it on to the child. PGD or Pre-implantation Genetic Testing aims to select only the embryos with normal chromosomal count and only these embryos are implanted to achieve a healthy pregnancy and bring down the number of children affected with a chromosomal anomaly.

The risk of Aneuploid pregnancy:

The older a woman is when she tries to conceive (aged 35 or more), the higher the risk of Aneuploid pregnancy (carrying a baby with genetic or chromosomal abnormality). Most of these pregnancies end in miscarriages and the few that come to term produce babies with chromosomal abnormalities.

Causes of Chromosomal Abnormality:

Usually, chromosomal abnormalities occur due to an error in the cell division. Meiosis refers to the cell division, which the sperm and the egg undergo during the development procedure. Normally, meiosis breaks the chromosomal material into two equal halves, so that each of the parents contributes 23 chromosomes to the pregnancy. However, when the number of chromosomes in the cell goes up or down than the normal, it results in genetic/chromosomal anomalies.

PGD Procedure for a Chromosomal Anomaly:

If a couple elects to go for Pre-implantation Genetic Diagnosis, they have to undergo ICSI Cycle. ICSI cycle initiates a fertilization cycle to produce embryos. When the embryos reach upto day 5 and blastocyst are formed, they are biopsied and further sent to genetic lab for detecting the chromosomal abnormalities. The embryos are incubated for the entire duration of the genetic screening. Only the embryos that the genetic test clears are implanted. PGD never reveals the gender of the embryo.

PGD can help detect the single genetic disorders that may lead to the following ailments:

  Cystic fibrosis
  Muscular dystrophy
  Tay-Sachs
  Sickle cell anaemia
  Thalassemia
  Turner syndrome

PGD is a revolutionary science that can help root out incurable disorders linked to genetics. It ensures that pregnancy is sustained until term and a healthy baby is born.

Suffering From Genetic & Chromosomal Anomalies - Know About PGD!

One of the worst neurological disorders to have is dementia. It is a general term used to describe cognitive decline of the brain. It s not specific disease but denotes several brain disorders and mental illnesses. A person suffering from dementia can have severe impairment in judgment, loss of memory and thinking. Dementia is a very difficult disease not only for the patient but also for their families and caregivers. 

Some facts about dementia are as follows:

It s not a mental disorder occurring in old age but it does degenerates with age.
An estimation of 47.5 million people worldwide suffers from dementia and 60% of these people live in low and middle-income countries and according to WHO this figure is likely to increase.
Every 4 seconds a new case of dementia is reported
Dementia is a collective term to describe the many types of in people, such as 

Alzheimer s Disease: It is one of the most common type of dementia accounting for 60-80% of dementia case. People suffering from Alzheimer s have fewer nerve cells and the size of the brain shrinks.
Vascular Dementia: Another most common form of dementia occurring after a stroke.
Lewy Body Dementia: It is neurodegenerative condition that involves a protein called alpha-synuclein which changes the brain. Symptoms may be similar to Parkinson s disease.
Symptoms of dementia can range from mild to moderate to severe that includes:

Memory Loss
Disorientation meaning inability to focus or pay attention
Changes in visual perception
Impairment in reasoning and judgment
Dementia can be caused by damage to brain cells or progressive brain cell death. As a result communication between brain cells become difficult. Other symptoms include:

Stroke
Brain Tumor
Head Injury
Prion Disease
HIV Infection
Reversible Factors

There are no definite tests for dementia. Doctors and neurologists have to medical history, blood tests and CT scans to find out whether a person has dementia or not. However, the most potent evaluation comes from a set of questions that are asked to a patient suspected of having dementia. The ability to answer those questions correctly is one of the best diagnoses for dementia.
There is no specific treatment for dementia as it is not a curable disease and degenerates with time. However, medicines or drugs given for Alzheimer s can be given to people suffering from dementia.
Although results vary depending upon a person s lifestyle s and habits, doctors suggest eating healthy, exercising regularly, and stopping smoking and drinking may prevent some types of dementia.
The best treatment for dementia is to treat the person with care and love so that they don t feel neglected.
Dementia is often associated with old age but that is not always true. It is important to gain knowledge and educate others also.

Dementia - Quick Facts You Must Know About It!

Post-traumatic stress disorder (PTSD) is an abnormal condition of the mind that develops when a person is exposed to certain traumatic events in life such as accidents, sexual assault or warfare.

The major symptoms of PTSD are:

Reliving the traumatic experience over and over again; this leads to severe and long-term mental distress.
Recurring dreams about the events.
Provocation of traumatic thoughts by the slightest event that causes distress to the individual.
Avoiding memories and thoughts that might remind them of the event.
Developing a negative view of themselves and the world.
Developing social or specific phobias.
Treatment

Medication and antidepressants: Medicines such as paroxetine, sertraline and selective serotonin reuptake inhibitor (SSRI) help the individual address insomnia related problems that occur due to PTSD and suppress nightmares.
Psychotherapy: This form of therapy is used to cure both mental health conditions (such as obsessive compulsive disorder, anxiety and depression) as well as emotional problems that result from PTSD. Skilled mental health experts are needed for this form of treatment to be administered. They would listen to each individual patiently and provide effective strategies to give solutions to the problems. Some of these therapies are:
Cognitive Behavioural therapy: This therapy enables the individual to adapt to changes and recognize thought patterns which lead to irrational and negative behaviour and actions.
Exposure therapy: This therapy causes the affected individual to first become anxious by exposing him/her to the traumatic memories, situations and objects by simulating them. The therapy helps the person to overcome his/her fears and become comfortable in the same environment that had previously caused fear and anxiety.
Group therapy: This popular and effective form of therapy allows the individual to share his/her feelings, fears and thoughts with a group of people who have themselves experienced similar trauma in their lives. Sharing such experiences helps reduces stress levels.
Some Self-Help and Coping Tips include:

Avoiding situations that cause PTSD can worsen the condition. Hence, the individual should try to embrace and face such situations boldly.
PTSD can result in loss of motivation and stress. Try utilizing your time in socialising, indulging in certain or even exercising for that matter.
Taking some time out to relax and having fun is very important. This calms the body and mind, thereby improving one s mood.

PTSD - 6 Major Signs + Treatment

Causes and symptoms of anorexia

Anorexia is a common eating disorder which is identified by abnormally low body weight, intense fear of gaining weight and a distorted perception of body weight. The problem is not only related to your dietary patterns but it also related to your mental state. People with this disorder are generally self-conscious, have a low self-esteem and are overly concerned about their external appearance.

Causes of anorexia

Biological factors - These factors represent that anorexia can be congenital or it may have developed over time. Congenital means that disorder is hereditary in nature and is passed on from the parents to the offspring. On the other hand, it may develop in people who are more sensitive and have an inclination towards perfection.
Psychological factors - Anorexia can also be caused due to certain specific personality traits and emotions that might be possessed by you. For instance, anorexia is more likely to happen to young women who are really worried and conscious out the way they look externally. Additionally, people who are either emotionally not too strong or suffer from anxiety issues can develop this disorder easily.
Environmental factors - The type of a cultural set up you are living in also plays an important role in developing this disorder. For instance, the western culture is all about slim and fit people, whereas the oriental countries are not so bothered about the same.

Symptoms of Anorexia

Emotional symptoms - This category of symptoms includes behaviors and a thought process aimed towards losing weight and minimizing your food intake. Some of the symptoms belonging to this type include:

Forceful vomiting to lose calories
Staying hungry
Excessive physical activity or exercise
Denial of hunger
Social withdrawal
Irritability
Depressed moods

Physical symptoms - These symptoms are self-explanatory and are clearly visible on the human body. These include:

Extreme weight loss
Thin appearance
Abnormal blood count
Fatigue
Insomnia
Dizziness or fainting
Discoloration of the fingers
Hair that thins, breaks or falls out
Soft, downy hair covering the body
Constipation
Low blood pressure



Causes and Symptoms of Anorexia

How To Control Nerve Pain?
Nerve pain or peripheral neuropathy, as it is medically known, is characterized by pain, numbness and weakness that arise out of nerve damage. This pain is usually restricted to the feet and the hands.
What are the common causes?
Diabetes is the most common cause for this condition. However, other causes, such as injuries, infections and prolonged exposure to certain toxins can also trigger nerve pain.
How can you control nerve pain?
Nerve pain can be managed and taken care of at home taking into consideration the points that have been mentioned below:
Topical Painkillers: Certain over the counter ointments and creams can help relieve nerve pain. These medications act as local anesthetics; that is they numb the area of the pain. Capsaicin, a derivative of chili peppers, is one of the major ingredients used in these medicines. Others use botanical oils as the major ingredients.
Painkillers: There are painkillers available OTC which can curb nerve pain. However, painkillers such as ibuprofen, aspirin and acetaminophen do not really work well for severe pain of the nerves.
Supplements: The lack of Vitamin B12 is considered to be a very important cause, and at times, a catalyst for nerve pain. In a case such as this, Vitamin B12 supplements or injections might be administered. Although more research needs to go into this, but certain supplements, especially gamma-linolenic and alpha-lipoic acid can help soothe nerve pain caused by diabetes.
Acupuncture: This time honored Chinese approach is a proven alleviator of nerve pain. Acupuncture releases chemicals which numb the pain, or prevent the pain signals from travelling to the brain.
Physical Therapy and Massages: Physical Therapy can especially heal and strengthen weak muscles that can stem from acute nerve damage and pain. Though more evidence is needed, according to a few sufferers of this condition, massages can be helpful with the tremendously painful muscle spasms that can so often result from nerve pain.
Relaxation Techniques: In combination with the above mentioned approaches, relaxation techniques can go a long way in relieving debilitating neural pain. Besides being helpful with dealing and reducing a few stress phases of life which can cause nerve pain, these techniques might actually root out the actual pain itself.
Lifestyle Modifications: This one s always a winner! Eating a well-balanced diet that guarantees all nutrients in uniform amounts can never go wrong. Regular exercises for about 30-45 minutes can remedy different types of pain; nerve pain being one of them. Try and limit alcohol intake (a peg once a week won t harm one, but binge drinking can play the ultimate spoilsport and make all health plans go topsy-turvy!). Abstain from smoking or chewing tobacco as this is usually the primary contributor towards any medical condition or disorder.

Nerve Pain - 7 Ways You Can Control it 

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