Schnitzler s syndrome is a very rare condition described by a reddish rash that looks like hives (urticaria) and lifted levels of a particular protein in the blood (monoclonal IgM gammopathy). Symptoms connected with the Schnitzler disorder may include increased levels of fever, joint inflammation, joint pain (arthralgia), bone agony, and different discoveries, for example, swollen lymph nodes (lymphadenopathy). It also causes weight reduction, discomfort, exhaustion, and broadened spleen and liver. This condition should be treated in terms of taking care of the symptoms so that they do not become debilitating.

Some of the other symptoms include the following:

Urticaria (hives) depicts red raised patches of the skin. These are once in a while irritated. They may last for about 12 hours to 3 days. This may become severely painful if not treated in time.
80% of such patients suffer from painful or swollen. A few patients experience bone pain as well.
High fever might be there accompanied by chills and night sweating. This can give rise to further uneasiness and is usually caused when the immune system is attacked by the ailment.
One of the main symptoms of the Schnitzler disorder is monoclonal gammopathy. This mostly means a raised level of immunoglobulin M (IgM)
Reasons behind it

The main cause behind the Schnitzler syndrome is unknown. Specialists believe that particular parts of the immune system may not work appropriately in the end because of the Schnitzler syndrome. Individuals with the Schnitzler disorder additionally have monoclonal IgM gammopathy, in which abnormal production of immunoglobins result in elevated levels of immunoglobulin M (IgM) in the body. Immunoglobulins are proteins delivered by the white blood cells. A few analysts believe that IgM antibodies accumulate in the skin (epidermis), setting off a reaction that causes the rash. At the time of diagnosis, IgM levels may just be somewhat raised and may stay stable for quite a long time.

Diagnosis

The diagnosis of the Schnitzler disorder is based upon an intensive clinical assessment, patient history, rejection of different other disorders and proof of fever, joint pain or aggravation, bone pain, discernible lymph nodes, amplification of the liver or spleen, lifted quantities of white platelets (leukocytosis), raised red platelet (erythrocyte) or anomalies, which can uncover expanded bone thickness (osteosclerosis).

Treatment: 
Anakinra is a successful treatment for Schnitzler syndrome. It is also very commonly used to treat rheumatoid joint inflammation. The following medicines and therapies have been proven to be successful for treating the Schnitzler disorder over a period of time. These are as follows:

Antihistamines
Nonsteroidal calming specialists
Systemic steroids (prednisone)
Hydroxychloroquine
Colchicine
Dapsone
Pamidronate
Thalidomide
Pefloxacin
Phototherapy
Immunosuppressive specialists (ciclosporin, methotrexate, cycloposphamide)
Biologic specialists (tocilizumab, rituximab)
The Schnitzler disorder is a long-term infection, so stopping a promising treatment can tend to cause a relapse and may cause the disease to reappear. Also, the medicines mentioned above should not be taken without consulting a doctor as they can have sever side effects, if not administered under the guidance of a physician.

Schnitzler Syndrome - Things You Must Know About It!

Changes in the tissue and tone of breasts are a part of the natural ageing process. The breasts are made of fats and ligaments but there are no supporting muscles to hold them up. So, with time, they lose their firmness. But PRP treatment can reverse this trend. 

What are the Reasons behind Breasts losing their Firmness? 

  Age: this is the chief cause of loss of breast firmness. As a woman ages, the ligaments of her breasts lose their elasticity and stretch out. The support framework of fats disintegrates and the breasts lose their fullness. 

  Gravity: the earth s gravitational force is always exerting pressure on the breasts and keeps pulling them down. 

  The wrong type of bra: a very large population of women have no idea which type and size of bra would suit them. Bras are supposed to give the breasts lift and support and prevent them from being jostled about because of movement. This applies especially during work out. Unless she is wearing the perfect fit, the breasts will begin to sag. 

  Smoking: cigarette contains carcinogens which are known to make the breast ligaments lose their elasticity. 

  Weight fluctuations: rapidly gaining weight and then shedding it gain cause an alternate stretching and tightening of breasts. Stable weight is good for the health of breasts. Misshapen breasts can be a blow to an individual s self-image and confidence. That is why many women are opting for contouring of breasts through surgery. And the surgery that is gaining ground these days is PRP therapy. 

What is PRP? 

Plasma Rich Platelet therapy is a revolutionary technology. Blood from the person who is to undergo the procedure is drawn and the plasma is extracted by using centrifugal force. Then the plasma rich platelets are inserted into the chest. PRP can trigger the growth of new cells and tissues where the old ones had withered. It tightens the loose skin around the breasts, improves blood circulation to boost rejuvenation. This treatment also speeds up stem cell growth and production of collagen and helps to contour the breasts. 

What are the Benefits of PRP therapy? 

  It is a non-surgical and non-invasive procedure

  It heals in no time 

  It does not leave a scar or marks 

  Removes breast wrinkles and reveres inverted nipples Most doctors advise their patients to rise above societal pressure to adhere to beauty standards.

However, if people still feel the need for a breast contouring, PRP is the safest and most efficient way to go about it. 

Breast Firmness & Contouring - Can PRP Help?

We all think of sunscreen as something that goes into our vacation kit when heading out on a hike in the hills or to the beach. What we fear is being out in the sun can reduce fairness, can cause a tan, and a sunscreen will help maintain complexion.

Well, these are completely wrong notions. What we need to be aware of is that even the regular, daily sun exposure during driving or going to the office can do as much damage, if not more. The sunscreen, therefore, assumes a very important role in your daily personal care. Read on and find out more.

Relationship with skin cancer: Studies in the US have shown that skin cancer is the most common type of cancer and sun exposure is the leading cause of this. It is the regular exposure on a daily basis that cumulatively leads to this, rather than a one day exposure minus the sunscreen. Using sunscreen on a daily basis provides a good shield against skin cancer.

Slows down aging: Dry skin, wrinkles, sun spots, and dark circles on the skin are more related to unprotected exposure to the sun rather than just aging. The sun is the most powerful agent that can lead to these effects and it is very essential to guard yourself against it.

While a general belief is that the sun is less harmful during cloudy days, it is not so the case. The ultraviolet rays of the sun filter through clouds and can cause equal damage as they would during sunny summer days. Studies have shown that the rays, which filter through the clouds are capable of accelerated aging effects and continue to do so, even after you have reached home.

It is not just the amount of time, you are actually out in the sun that counts. The collagen in the skin that gives it the firmness, if is damaged, leads to sagging and bagging of skin. Using a sunscreen provides a shield against these harmful ultraviolet rays.

Research has shown a 73% reduction in the invasive forms of skin cancer by using sunscreen on a regular basis. It is a popular belief that fair complexion is more affected by exposure to the sun. It is true that darker complexion has more melanocytes that increase the natural protection, but this does not ensure complete protection against the harmful ultraviolet rays.

After reading this, a sunscreen lotion with a sun protection factor (SPF) of 15 or more should surely find its way into your grooming kit.

Why Do You Need To Use Sunscreen Daily?

Swollen breast tissues in men or boys caused by hormonal (testosterone and estrogen) imbalances is called gynecomastia. Both breasts or one breast, can be affected by gynecomastia. At any point in life, from birth to puberty, even in adulthood, you might develop gynecomastia. Most of the times, gynecomastia is caused by hormonal imbalances, but there might be some underlying causes as well.
Gynecomastia is normally not a serious condition, but it can be difficult to deal with the pain and embarrassment.
It can be cured with surgery or medication, if it doesn't go away on its own.

Symptoms and signs of gynecomastia include
a) Enlarged glands in the breast tissue
b) Tenderness in the breast

The causes that trigger gynecomastia include
1. Hormonal changes: Testosterone and estrogen control the sexual development in men and women respectively. Estrogen is not a hormone that only women produce; men produce it too. When the production of testosterone and estrogen are thrown out of balance, gynecomastia occurs.
2. Medication: Certain medications such as anabolic steroids, androgens, HIV/AIDS medicines, antibiotics and chemotherapy can cause gynecomastia.
3. Drugs and alcohol: Substances such as alcohol, marijuana, amphetamines, heroin and methadone cause gynecomastia.
4. Health condition: Certain factors, such as aging, hypogonadism (hormonal disorder), hyperthyroidism (overactive thyroid gland), tumors, kidney failure, cirrhosis, liver failure, malnutrition and starvation can lead to gynecomastia.
5. Herbal products: Essential oils derived from plants such as lavender or tea tree, used in lotions or shampoos, have weak estrogenic actives. They have been said to cause gynecomastia.

Gynecomastia can be cured either with medication or surgery. Surgical options for gynecomastia are, however, limited. The two surgical options for gynecomastia include:
a) Liposuction: Liposuction only removes the fat from the breast, not the breast gland tissue. It has fewer complications, there is limited or zero blood loss and there is less distortion of the nipple.
b) Mastectomy: Mastectomy removes the gland tissues in the breast. The surgery uses minimal incisions to remove the gland tissue. Also, it involves less time to recover.

Treating Gynecomastia With Surgery

If you see continual and long-term white patches of depigmentation on your skin, it could be vitiligo. Vitiligo is a condition that appears when melanocytes in your skin are no more alive. This bunch of cells is responsible for producing the melanin pigment that endows the skin with its colour as well as protects it from the harmful UV rays. The area which may be affected by this dermatological disease varies from person to person, and it can also affect the hair, mouth and eyes as well. In most cases, the vitiligo affected area stays discoloured for the rest of the patient s life.

Various types of vitiligo and their symptoms
Scientists have classified vitiligo into two types: segmental and non-segmental. The non-segmental vitiligo is the most common variant and 90 percent of vitiligo affected patients suffer from this kind of disorder. In this disease, the patches take place with little symmetry on both sides of the body. It can be further broken down into 5 sub-divisions.

Generalised vitiligo: It can occur at any part of the body without any rules, and this is by far the most common type.
Acrofacial vitiligo: It is mostly seen on the toes and fingers.
Mucosal vitiligo: In this condition, the discolouration normally takes place around the lips and mucous membranes.
Universal vitiligo: This is the rarest type of vitiligo where the whole body is covered in white patches.
Focal vitiligo: This is most commonly found in children. The children have white and scattered patches across the body.
Possible treatments for vitiligo

Though there are no treatments possible that will re-pigment your skin to its original colour, there are several remedies that aid in decreasing the visibility of white patches on the affected areas of the skin. Some of them include:

Phototherapy with UVB radiation: This is a common form of treatment where the affected area is exposed to UVB radiation and can be performed at home too. If you have large white spots across the body, it is important to have the treatment performed by an expert at any healthcare centre.
Phototherapy with UVA radiation: In this treatment, a drug is first administered for increasing skin s sensitivity to this radiation. Then the affected area of the skin is exposed to high doses of UVA radiation.
Skin camouflage: In mild cases of vitiligo, cosmetic creams and make-up can be used to camouflage the affected area. It can last for about 12- 18 hours when applied in proper techniques.
In case you are suffering from vitiligo, it is crucial to speak with an expert and opt for the best means to curb down the impact of vitiligo.

Vitiligo - Signs You Are Suffering From It!

We have for ages seen our parents and our grandparents reach out for a piece of jaggery at the end of every meal. Jaggery is healthier compared to refined sugar because of its deposition of phytochemicals and other important minerals. While many people do not choose jaggery because of its no-so-good-appearance, it is perhaps more sensible to consume it considering the host of health benefits it offers.

Here is a list of benefits that can be extracted from the consumption of jaggery.

Skin benefits: Jaggery nourishes the skin in the true sense of the word. Owing to the numerous amount of mineral and vitamin, it can eliminate common skin problems such as pimples and acne. It can negate dark spots, wrinkles delay the common signs of aging.
Digestive benefits: Jaggery plays a huge role in ensuring smooth digestion. It stimulates secretion of digestive enzyme. It, therefore, makes it easy for the body to quicken the process of digestion. It can also help to stabilize the bowl movement by keeping common digestion related disorders such as constipation, intestinal worms, indigestion at bay.
Blood: Jaggery does a great job in purifying the blood. It acts as a cleansing agent by filtering the blood from the toxic agents. It also keeps the hemoglobin count normal and help the body refrain from blood-related disorders such as anemia. Since the quantity of iron content in jaggery is plentiful, it successfully helps the body to stay healthy and negate deadly diseases. Furthermore, jaggery can help women to stay away from complicated menstrual related disorders, beat weakness and fatigue.
Weight loss: Jaggery s rich potassium content helps the body balance the electrolyte, build muscles and improve the metabolism of the body. Potassium also helps in managing water retention in the body. Both the factors coupled together helps in weight loss and beat fatigue, obese etc.
Blood pressure: The sodium and potassium content of jaggery helps the body maintain an effective adequate acidic level. This ensures that the blood pressure remains in the balance and the body refrains from undue blood pressure related disorders.
Antioxidants: Jaggery contains selenium, the latter is a rich source of antioxidants which can help the body to fight the free radicals and keep it at bay. The antioxidants also help the body to stay away from other ailments.
Respiratory health: Jaggery is a great source of food that can effectively fight various respiratory problems of the body. It can fight diseases such as bronchitis and asthma.
Body temperature: Jaggery helps to keep a normal body temperature. This is extremely beneficial for patients suffering from asthma since maintaining a steady body temperature is sacrosanct for patients suffering from this disease.

Jaggery (Gur) - 8 Amazing Reasons Why You Must Eat It!

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