Vymada 50 Mg Tablet

Vymada 50 Mg Tablet is helpful in treating essential hypertension. It may have an advantage over losartan due to minimal metabolism requirements and consequent use in mild to moderate hepatic impairment.

This medication is combination of an anti-hypertensive drugs composed of Sacubitril and Valsartan. It is used for treatment and prevention of chronic heart failure and other heart conditions. The tablet works by inhibiting a prodrug neprilysin which reduces the strain on the failing heart.

Consult your doctor if you experience any side-effects such as low blood pressure, swelling in ankles and feet, feeling short of breath, fainting, dizziness and high blood potassium levels. Some other rare side effects include muscle weakness, painful urination, little or no urination, tingly feeling, slow heart rate, weak pulse, cough and renal impairment.

You should not use this medicine if you are allergic to it or if you have ever had a severe allergic reaction to any blood pressure medication. Patients suffering from diabetes, liver disease or a kidney disease should exercise caution.

Take exactly as directed; do not discontinue without consulting prescriber. Take first dose at bedtime. This drug does not eliminate need for diet or exercise regimen as recommended by prescriber.

• Hypertension

• Heart Failure

• Allergy

• Dizziness

• Drowsiness

• Ataxia

• Fatigue

• Hypotension

• Abdominal Pain

• Neutropenia

• Abnormal Liver Function Tests

• Cough

• Headache

• Nausea

• Edema (Swelling)

• Is It safe with alcohol?

  It is unsafe to consume alcohol while taking this medicine. Please consult your doctor.

• Are there any pregnancy warnings?

  Do not get pregnant while taking this medication; use appropriate contraceptive measures. If you are, or plan to be pregnant, notify your prescriber at once. Pregnant women must consult doctor before consuming this medication.

• Are there any breast-feeding warnings?

  Breastfeeding women should not use this medication. Please consult your doctor.

• Is it safe to drive while on this medicine?

  Occasionally dizziness or weariness may occur. Driving must be avoided while taking this medicine.

• Does this affect kidney function?

  Caution must be taken in patients with kidney disease. Adjustment of dose might be needed. Kindly consult your doctor before taking it.

• Does this affect liver function?

  Caution must be taken in patients with liver disease. Dosing adjustment is needed in hepatic impairment (mild - moderate): less than or equal to 80 mg/day. Kindly consult your doctor before taking it.

Below is the list of medicines, which have the same composition, strength and form as Vymada 50 Mg Tablet , and hence can be used as its substitute.

• Cidmus 50Mg Tablet

  Lupin Ltd

• Cidmus 50Mg Tablet

  Lupin Ltd

• Azmarda 50Mg Tablet

  Cipla Ltd

• Vymada 50 Mg Tablet

  Novartis India Ltd

• Are there any missed dose instructions?

  Missed dose should be taken as soon as possible. Skip your missed dose if it is the time for your next scheduled dose.

• Are there any overdose instructions?

  Consult your doctor in case of overdose.

This medicine blocks the enzyme neprilysin, which leads to the degeneration of atrial and brain natriuretic peptide. When these peptides remain excessively active the blood pressure is reduced, as the blood volume is lowered. It also brings about inhibition of combination to angiotensin II to AT1 selectively. This occurs within many tissues such as adrenal glands and smooth vascular muscles.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Consumption of alcohol is not advisable.

• Interaction with Medicine

  • Lithium: Risk of toxicity may be increased by valsartan; monitor lithium levels.
  • Potassium-sparing diuretics (amiloride, potassium, spironolactone, triamterene): Increased risk of hyperkalemia.
  • Potassium supplements may increase the risk of hyperkalemia.
  • Trimethoprim (high dose) may increase the risk of hyperkalemia.

• Interaction with Food

  If you are allergic to any food, please consult with the physician.

• Interaction with Disease

  Avoid use a smaller dose in patients who are volume depleted; correct depletion first. Deterioration in renal function can occur with initiation. Use with caution in unilateral renal artery stenosis and pre-existing renal insufficiency; significant aortic/mitral stenosis. Use caution in patients with severe renal impairment or significant hepatic dysfunction.

• Ques : What is Vymada 50 mg tablet?

  Ans : Vymada 50 mg is a medication which has sacubitril and valsartan as active ingredients present in it.

• Ques : What is Vymada 50 mg tablet used for?

  Ans : Vymada Tablet is a medication used for the treatment of Heart failure.

• Ques : What are the side effects of Vymada 50 mg tablet?

  Ans : Vymada 50 mg has some commonly reported side effects such as Renal impairment, Cough, Altered levels of potassium in the blood, Decrease in red blood cell count, Headache, Fainting, Decreased blood pressure, etc.

• Ques : Who should avoid taking Vymada?

  Ans : Vymada 50 mg should be avoided in patients who are allergic to any of its ingredients.

• Ques : How long do I need to use vymada 50 mg tablet before I see improvement of my conditions?

  Ans : This medication should be consumed, till the complete eradication of disease. It is advised to use, till the time directed by your doctor.

• Ques : At what frequency do I need to use vymada 50 mg tablet ?

  Ans : This medication is generally used once or twice a day, as the time interval upto which this medication has an impact, is around 12 to 24 hours.

• Ques : Should I use vymada 50 mg tablet empty stomach, before food or after food?

  Ans : The action of salts involved in this medication does not depend on using it pre-meal or post-meal. It is advised to consult a doctor before use and take it at a fixed time in a day.

• Ques : What are the instructions for storage and disposal of vymada 50 mg tablet?

  Ans : This medication contains salts, which are suitable to store at room temperature and keeping this medication above or below that, can cause inadequate effect. Protect it from moisture and light.

• Valsartan- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 09 May 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/valsartan

• Valsartan- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 09 May 2019]. Available from:

  https://www.drugbank.ca/drugs/DB00177

• Sacubitril- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 09 May 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/sacubitril

• Sacubitril- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 09 May 2019]. Available from:

  https://www.drugbank.ca/drugs/DB09292

• ENTRESTO- sacubitril and valsartan tablet, film coated- Daily Med [Internet]. dailymed.nlm.nih.gov. 2018 [Cited 09 May 2019]. Available from:

  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=000dc81d-ab91-450c-8eae-8eb74e72296f