Thalassemia Questions

The test results are not suggestive of thalassemia minor. There is still a possibility of silent variants and other forms of thalassemia (delta-beta etc).; however those are inconsequential and asymptomatic unless you are also a thal minor in which case your children will be at risk of moderate anemia.

Sorry to know that Few things Get a high resolution hla typing
This is can be searched for what is called as matched unrelated donor transplant which has 60 to 70 percent success and is a 10/10 match Watch for leukoreduced blood Iron over load Hepatitis b vaccination It can be done at 1 year of age Do no™t worry.

Hyperventilation due to anxiety is more of a "diagnosis of exclusion" than something to be actively investigated and diagnosis. This means, when all other possible causes of these symptoms are excluded and ruled out after a thorough work up, we make such a diagnosis in certain patients. As far as I know, there are no specific tests to conclusively diagnose hyperventilation due to anxiety. It is more of a clinical diagnosis, arrived from a detailed history and examination of the patient.

There is a 25% chance that your child may have Hemoglobin E disease. But relax. HbE disease patients are asymptomatic and can lead a healthy normal life off treatment.

In thalassemia you need first characterise that which phenotypic presentation you have major intermediate or minor and than accordingly one can manage. Till time avoid iron supplements and add folic acid.

No, it is not a life threatening disease.
Confirm the diagnosis with reliable labs, Hb-HPLC.
Precaution during the marriage age/period has to be taken.
He/she with Thalssemia minor should not marry a person with Thalassemia minor to avoid a offspring with Thalassemia major.
Thalassemia-'major' is a condition which requires life long blood transfusions, iron chelation or HLA matched Allogeneic stem cell transplantation.

Is it Thalassemia major or trait/minor.
If trait/minor no need of any treatment.
If it is major and family HLA match donor is available, Allogeneic stem cell transplant is the curative treatment. It is better to discuss Transplant treatment procedure with BMT/transplant physician working in good BMT/transplant center; it's not that simple to explain the procedures/indication/risk factors/outcome/expenditure here in this platform.
So, please, consultant Hematologist working in good tr...more

Its a genetic disease and you will not be symptomatic but during your marriage your husband should be thalassemia negative

Beta thalassemia trait is not a disease. You just are a carrier of the disease. You should just ensure that you marry somebody who is NOT a carrier of Beta thalassemia to ensure that your offspring has NO chance to have thalassemia. However in the scenario that you do eventually end up marrying somebody who is a carrier, you should first contact the local Thalassemia control center or a Hematologist to discuss what are tge steps and procedures do follow in your pregnancy to ensure that you do no...more

Ideally you can go for a hla matched sibling or unrelated transplant. However, transplant has its own problems. In that scenario regular blood transfusion and adequate iron chelation therapy should suffice to give a reasonable quality of life. However if you are adamant at cure a haplo transplant can also be done in thal major. But you must know that it is a costly procedure and can have many complications. However for that you need to consult a good centre with good expertise in haplo transplan...more