Systemic Lupus Erythematosus Questions

ANA is a type of antibody test usually positive in auto immune disorders some types of arthritis, vasculitis etc. But the titre of the test makes it significant. It can be positive in low titres like 1: 40 or 1: 80 in the general population without any disease as well. So the report has to be clinically corelated and cause for positivity has to be found out to treat it.

Because it usually takes some time for calcium to be deposited in a granuloma, it is generally assumed that a calcified granuloma is an old granuloma, or an old area of inflammation. For example, a calcified granuloma in the lung may be due to tuberculosis contracted years earlier that is now inactive and dormant.
Since a granuloma is a space occupying lesion in the brain, there are chances that it may press upon the adjoining tissues to produce symptoms.
Therefore, most of the patients ...more

Hi,
Thanks for your question on Lybrate
I do understand your concern "As" per your clinical history it is not a serious disease but organ damage is possible and it has no cure at all. Now at present Corticosteroid is the first line medication for this condition both orally as well as cream .TNF Alpha can be tried in some cases and organ transplant is required for liver and lungs.
Hope that helps.

Lupus vulgaris is a common type of reinfection TB. Diagnosis is made on skin biopsy with AFB stain which may or may not be positive. IF the afb stain is positive then diagnosis is confirmatory. If the afb stain is negative then a combination of clinical findings and serological tests like Mantoux test would be used by the referring clinician to start combination therapy for TB.

Can't be cured, but treatment may help. Requires a medical diagnosis
Lab tests or imaging always required. It is Chronic: meaning it can last for years or be lifelong
Lupus (SLE) can affect the joints, skin, kidneys, blood cells, brain, heart and lungs.
Symptoms vary but can include fatigue, joint pain, rash and fever. These can periodically get worse (flare up) and then improve.
While there's no cure for lupus, current treatments focus on improving quality of life through contro...more

Systemic lupus erythematosus (SLE) is a chronic inflammatory disease that can affect various organs of the body. Women with lupus are at higher risk for pregnancy complications such as preeclampsia and premature delivery, and those with antiphospholipid antibodies have an increased risk of miscarriage and stillbirths.

There is a risk of hereditary transmission for future generation, but it is not a must. You can go for genetic counseling.

, With steroid treatment blood glucose does increase, because corticosteroids are diabetogenic. One of the possible ways is to reduce the dose of steroid to minimum possible, plus use a long acting Insulin like Basalog (Glargine) plus a short acting insulin to control post breakfast & post lunch surges of glucose Thanks.