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Synovial Sarcoma Tips

Causes and Symptoms of Ewing's Sarcoma

Dr. Prashant Mehta 91% (32 ratings)
European Society For Medical Oncology certification, DM - Oncology, MD - General Medicine, MBBS, Fellowship in Bone Marrow Transplant
Oncologist, Faridabad
Causes and Symptoms of Ewing's Sarcoma

Collectively grouped under the Ewing sarcoma family of tumors, Ewing's sarcoma is the second most common form of bone cancer, which is commonly seen in children and adolescents. Very rarely is it experienced in adults above the age of 30.

Typically forming in the bones of the chest, pelvis, head, back or trunk and in the long bones of the arms and legs, Ewing's sarcoma is believed to originate in certain kinds of primitive cells. When it begins to affect similar kind of cells found outside the bone, it is usually called an extraosseous Ewing's sarcoma.

Causes
1. Similar to all types of Ewing tumors, Ewing's sarcoma is generally caused by an alteration in a certain cell compelling a gene named EWS found on chromosome no. 22 to move over to a DNA section on any one of the surrounding chromosomes resulting in the activation of the EWS gene.
2. While it is not a hereditary condition, it usually occurs after childbirth, but no substantial evidence has been found as to why it happens so.

Symptoms
Symptoms of Ewing's sarcoma may include:
1. Swelling and pain especially in the arms, legs, back, chest or pelvis

2. Swelling accompanied by joint immobility
3. A bone breaks having no apparent cause
4. Swelling which may or may not be accompanied by a warm, tingling sensation
5. Fever resulting from unknown causes
6. Lumps or bumps which do not subside over time
7. Abnormal weight loss
8. High levels of fatigue
9. Tumors which have spread over to the lungs may cause shortness of breath
10.Tumors spread over to the spine may cause weakness or even paralysis.

Because the symptoms of Ewing's sarcoma can hardly be distinguished from symptoms caused by other infections or injuries, an early diagnosis is absolutely necessary for a successive treatment. If you wish to discuss about any specific problem, you can consult an oncologist and ask a free question.

1968 people found this helpful

Ewing's Sarcoma - 10 Signs You Must Not Ignore!

Dr. Chandrakanth Mv 89% (130 ratings)
MBBS, MD(General Medicine), Fellowship Hemato - Oncology (Hemat-Oncology), DM(Medical Oncology), DNB(Medical Oncology)
Oncologist, Howrah
Ewing's Sarcoma - 10 Signs You Must Not Ignore!

Collectively grouped under the Ewing sarcoma family of tumors, Ewing's sarcoma is the second most common form of bone cancer, which is commonly seen in children and adolescents. Very rarely is it experienced in adults above the age of 30.

Typically forming in the bones of the chest, pelvis, head, back or trunk and in the long bones of the arms and legs, Ewing's sarcoma is believed to originate in certain kinds of primitive cells. When it begins to affect similar kind of cells found outside the bone, it is usually called an extraosseous Ewing's sarcoma.

Causes
1. Similar to all types of Ewing tumors, Ewing's sarcoma is generally caused by an alteration in a certain cell compelling a gene named EWS found on chromosome no. 22 to move over to a DNA section on any one of the surrounding chromosomes resulting in the activation of the EWS gene.
2. While it is not a hereditary condition, it usually occurs after childbirth, but no substantial evidence has been found as to why it happens so.

Symptoms
Symptoms of Ewing's sarcoma may include:
1. Swelling and pain especially in the arms, legs, back, chest or pelvis

2. Swelling accompanied by joint immobility
3. A bone breaks having no apparent cause
4. Swelling which may or may not be accompanied by a warm, tingling sensation
5. Fever resulting from unknown causes
6. Lumps or bumps which do not subside over time
7. Abnormal weight loss
8. High levels of fatigue
9. Tumors which have spread over to the lungs may cause shortness of breath
10.Tumors spread over to the spine may cause weakness or even paralysis.

Because the symptoms of Ewing's sarcoma can hardly be distinguished from symptoms caused by other infections or injuries, an early diagnosis is absolutely necessary for a successive treatment. In case you have a concern or query you can always consult an expert & get answers to your questions!

3135 people found this helpful

Top Facts About Uterine Fibroids!

Dr. Gitanjali 97% (2639 ratings)
MS - Obstetrics and Gynaecology
Gynaecologist, Delhi
Top Facts About Uterine Fibroids!

Also referred to as myomas or leiomyomas, uterine fibroids are the most common form of uterine tumors. In a recent study, it was found that about 70 to 80 percent of women are likely to be affected by uterine fibroids by the age of 50. And the most vulnerable age of developing uterine fibroids is between the age of 40s and early 50s.

What are uterine fibroids?
Fibroids are harmless and noncancerous tumors even though sometimes, they can give way to a rare form of cancer known as uterine sarcoma. But there is no precise way of detecting sarcoma expect when surgery is performed for removing fibroids. If you have uterine fibroids, it is important to discuss your risks for having uterine sarcoma with your doctor. Women who hail from Africa and America are more likely to have uterine fibroids. These fibroids tend to grow at a very young age and lead to more severe symptoms. You may also have increased risk of uterine fibroids in case you have never been pregnant or are severely obese.

Some women have uterine fibroids, but they don’t have any symptom or discomfort, and the number of such women is usually high. It is generally perceived that a woman with uterine fibroids who don't have any symptoms would not require much treatment other than general observation.

What are the most common symptoms of uterine fibroids?
Even though numerous symptoms are associated with having uterine fibroids, the most common of them are having heavy menstrual flow with blood clots. It can also cause bleeding when you are not supposed to have menstruation, urge to pass urine frequently, abdominal bloating, pelvic cramping, and painful sex.

Even though you can still get pregnant while having uterine fibroids, you are likely to face various difficulties since these small lumps can alter the size as well as the shape of the uterus.

What is the most common treatment option for uterine fibroids?
Scores of hysterectomies, which is the medical term given to the surgical removal of the uterus, are performed each year for uterine fibroids. It not only snatches away the power to procreate but also carries its own risks and complications.Doctors suggest this option when uterine fibroids are very painful, or other treatment options have failed to eliminate the symptoms.

But the good news is that hysterectomy is not the only option for treating uterine fibroids. Other treatment options include myomectomy which is the surgical removal of the fibroid, hormone therapy to shrink the fibroid, Uterine Fibroid Embolization that stops the blood supply to the fibroid thus shrinking it, and Ultrasound to destroy the fibroids.

When you are nearing or in menopause, you can monitor the condition as the fibroids tend to shrink due to drop in the levels of estrogen and progesterone. In case you have a concern or query you can always consult an expert & get answers to your questions!

3045 people found this helpful

How Does Rheumatoid Arthritis Feel?

Dr. Vishwas Virmani 91% (22727 ratings)
MPT, BPT
Physiotherapist, Noida
How Does Rheumatoid Arthritis Feel?

RHEUMATOID ARTHRITIS: THE INFLAMMATORY DISEASE Rheumatoid arthritis usually begins slowly but sometimes comes on suddenly. Symptoms may appear, go away, and return again. While it is a systemic disease of inflammation, the most noticeable symptoms are vaguely or acutely sore joints of the hands and feet. The inflammation also affects the connective tissues throughout the body, which may contribute to a sick all over feeling. Rheumatoid arthritis begins with inflammation in the synovial membrane, a thin tissue that lines the capsule surrounding the joint.Inflammation of the synovial membrane may spread to other parts of the joint.Inflamed tissue may grow into the cartilage surroundings the bone ends, causing it to deteriorate. When the cartilage disintegrates, scar tissue forms between the bone ends. Sometimes the scar tissue solidifies into bones, fusing the joint, making it rigid and difficult to move.

HOW DOES RHEUMATOID ARTHRITIS FEEL?

Different people have different symptoms, but characteristically pain and stiffness occur in the morning and subside during the day. If you have this disease, getting up in the morning may be the hardest part of the day for you. While a few minutes of stiffness in the morning may be normal, people with inflammation due to rheumatoid arthritis are frequently stiff for one or two hours.Usually more than one joint is affected by rheumatoid arthritis. As the joints stiffen, swelling and tenderness become more apparent.Full motion becomes painful and difficult. When rheumatoid arthritis affects the hands, the fingers may become deformed and everyday takes become difficult to perform. The pain may become more severe with strenuous activity.Because rheumatoid arthritis often affects connective tissues throughout the body, there may be fever, poor appetite, weight loss,and anemia. The spleen and lymph glands may become enlarged. Early diagnosis and treatment can reduce the possibilities of dangerous and crippling effects. 

2 people found this helpful

How With Acupuncture & Acupressure Rheumatoid Arthritis Can Be Treated?

Dr. Healer Nazir Sheriff 87% (94 ratings)
BSAM
Acupressurist, Chennai
How With Acupuncture & Acupressure Rheumatoid Arthritis Can Be Treated?

Your immune system which can make you more susceptible to environmental factors, such as infection with certain other viruses and bacteria that may trigger the disease. Rheumatoid arthritis occurs when your immune system attacks the synovial membrane connected to two bones. The resulting inflammation thickens the synovial membrane, which can eventually destroy the cartilage and bone within the joint.

The tendons and ligaments that hold the joint together weaken and stretch, which eventually causes the patients to suffer with sever joints pain. Pain killers often have their own side effects and threaten the immune system further down the line. 

It jas been noticed that some patients experience extreame pain and in some cases the severity of the problem is such that they loss their feet and hand shape and it becomes more rigid and bend into different directions, some time they not able to pick up even light weight items, which can be easily done by a small child.

With acupressure and acupuncture we can concentrate on the problem and prevent it from becoming severe. And, eventually treat it step by step by correcting Immune system of patients. Some of the cases treated successfully have resulted in bringing the original shape back for fingers affected by Rheumatoid arthritis.

Achieveing something like this through acupressure and acupunture is possible by requires long term treatment and dedication on the part of the patient. In case you have a concern or query you can always consult an expert & get answers to your questions!

3303 people found this helpful

Knee Anatomy - Better Understanding Helps Prevent Knee Injuries!

Dr. (Prof) Amit Kumar Agarwal 88% (10 ratings)
MBBS, MS - Orthopaedics, M.Ch - Orthopaedics, MCh - Trauma and Orthopeadic Surgery
Orthopedist, Ghaziabad
Knee Anatomy - Better Understanding Helps Prevent Knee Injuries!

The knee joint is the meeting point of several bones. The knee bone's connected to the thigh bone at knee joint. The thigh bone or femur is the longest bone in the human body and it sits directly above the knee. Below the knee joint lies the shinbone or tibia down to the ankle. Tibia is partnered with the fibula, which runs along the outside of the leg. The kneecap also called as patella lies in between, protecting the knee joint. When the leg bends, the patella moves on the front part of the femur.

Knee Joint Compartments - 

Arthritis affects the ends of the bones, or spots where the bones in the knee joint move against each other. The joint capsule is a thick ligamentous structure that surrounds the entire knee that contains synovial membrane which provides nourishment to all the surrounding structures. The synovial fluid produced by the synovial membrane lubricates the knee joint. The capsule itself is strengthened by the surrounding ligaments.

Cartilage in the knees - 


Cartilage covers up the knee joint's ends thus keeping the bones from rubbing together and creating friction. This makes cartilage critical to keeping the knees pain-free when one is running, walking bending or squatting. There are two types of cartilage in the knee joint. Meniscus cartilage makes up the crescent-shaped disks on the inside and outside of the knee between the femur and tibia. Meniscus cartilage works like a shock absorber, providing cushion to the joint when walking to running. Joint or articular cartilage covers the bones of the knee, making smooth and friction free movement.


Cartilage is about eighty percent water when we are young, and can lose water content over time to drop to about seventy percent. The knees are filled with fluid that helps to keep the cartilage smooth and slippery. If this fluid is too much can stretch out the joint and less can lead to friction between the bones.

Hence, it is imperative to know how the parts of the knee joint work together, as it is the first step one can take to maintain or restore knee health. In case you have a concern or query you can always consult an expert & get answers to your questions!

 

 

2376 people found this helpful

Baker Cyst

Senior Registrar/ Research Associate, MS - Orthopaedics, MBBS, MCh. Orthopedics
Orthopedist, Ghaziabad
Baker Cyst

What is Baker Cyst and its causes?
A baker cyst is a swelling in the space behind the knee. It is also known as popliteal cyst. It causes stiffness and knee pain. Baker Cyst is common nowadays and can be caused by virtually any cause of joint swelling. The pain caused by popliteal cyst is more worsens if the patients fully flexes or extends the knee or moves around .The excess joint fluid (synovial fluid) bulges to back of the knee to form the baker cyst. Ostearoarthritis is the most common type of arthritis associated with Baker’s Cyst. And Juvenile arthritis is one of another cause of baker cyst in children. Baker Cysts is more common in females of 40 plus age or above. Baker cysts also can result from cartilage tears which include torn meniscus, rehematoid arthritis and other knee problems.

What are the symptoms of Baker Cyst?
Joint locking, knee pain, swelling and calf pain are some of the symptoms of baker cyst. Swelling or lump behind the knee is more common symptom and this is more evident while standing or performing any activity of knee.

 

6 people found this helpful

What Patients With Knee Pain And Swelling Should Know?

Senior Registrar/ Research Associate, MS - Orthopaedics, MBBS, MCh. Orthopedics
Orthopedist, Ghaziabad
What Patients With Knee Pain And Swelling Should Know?

​​​​​​Baker Cyst is one of the common cause of pain and swelling in the space behind the knee. It is also known as popliteal cyst. It causes stiffness and knee pain. Baker Cyst is common nowadays and can be caused by virtually any cause of joint swelling. The pain caused by popliteal cyst is more worsens if the patients fully flexes or extends the knee or moves around .The excess joint fluid (synovial fluid) bulges to back of the knee to form the baker cyst. Ostearoarthritis is the most common type of arthritis associated with Baker’s Cyst. And Juvenile arthritis is one of another cause of baker cyst in children. Baker Cysts is more common in females of 40 plus age or above. Baker cysts also can result from cartilage tears which include torn meniscus, rehematoid arthritis and other knee problems.

What are the symptoms of Baker Cyst?
Joint locking, knee pain, swelling and calf pain are some of the symptoms of baker cyst. Swelling or lump behind the knee is more common symptom and this is more evident while standing or performing any activity of knee.

HIV - Know Its Impact On Body

Gautam Clinic Pvt Ltd 93% (7776 ratings)
Sexologist Clinic
Sexologist, Faridabad
HIV - Know Its Impact On Body

HIV, which is short for Human Immunodeficiency Virus, penetrates your body and directly attacks your immune system. In this process, the virus weakens your body's natural defense mechanism against diseases and infections. A compromised immune system makes the body prone to minor infections, which healthy people would generally overcome. The virus itself doesn't cause any physical symptoms. It only serves to ease the entry of other bacteria and viruses into the body.

The following are some of the ways HIV affects your body:
1. Immune system - The human immunodeficiency virus destroys CD4 cells, the white blood cells that help the immune system ward off foreign substances. If left unchecked, HIV can develop into AIDS. During such time, the virus may damage the immune system to an extent that it wouldn't be able to ward off minor infections that a healthy immune system would. A person with HIV could thus suffer from fever, chills, sweats, shortness of breath, white spots in the mouth, fatigue, skin rash and weight loss from time to time.
2. Respiratory system - As HIV develops into AIDS, the body can contract infections such as pneumocystis pneumonia (PCP), tuberculosis and Kaposi's sarcoma. These conditions lead to serious respiratory problems. PCP is found to be one of the most common infections among people with HIV. 85% of the people would develop the infection if the condition is left untreated.

3. Skin problems - As in healthy individuals, many skin conditions can also occur in people with HIV or AIDS. But a compromised immune system heightens the condition and causes difficulty in treatment. Dermatitis, psoriasis, and hives are common conditions. They are also prone to a rare type of skin cancer known as Kaposi's sarcoma.
4. Gastrointestinal System - Gastrointestinal disorders are the most common ailments for people diagnosed with HIV and AIDS. Problems faced include diarrhea, nausea, vomiting, weight loss, abdominal pain and gastrointestinal bleeding. 50% of the people suffering from HIV encounter gastrointestinal disorders at some point of their illness. If you wish to discuss about any specific problem, you can consult a Sexologist.

6873 people found this helpful

Uterine Cancer - Who Is At Risk?

Dr. Dinesh Singh 86% (71 ratings)
MBBS, MD-Radio Therapy
Oncologist, Ghaziabad
Uterine Cancer - Who Is At Risk?

Cancer, be it in any part of the body, has an increased success rate of cure and survival, when it is diagnosed early. The same is true with uterine cancer, the most common form of female reproductive cancer. However, unfortunately, a limited section of the society is aware of the necessary information about this fatal disorder, which is incidentally treatable if caught at early stages. To help the cause, here is a brief note on what one should be aware of when it comes to uterine cancer.

What is uterine cancer?
Cancer which begins at the tissue lining of the uterus also referred to as the endometrium, is called uterine or endometrial cancer which occurs due to the abnormal growth of the cells that can invade the other parts of the body. Some people tend to confuse this with uterine sarcomas which start developing when there is cancer growth in the muscles and other supporting tissues in the uterus. Also, uterine sarcomas account for a small percentage of cancers in the uterus.

Who are at higher risk of being affected with uterine cancer?
It is presumed that post-menopausal women are at a higher risk of being affected by uterine cancer. The average women diagnosed with the disease is 60 years. It is very uncommon in women who are aged below 45 years, and the causes are not yet precisely known.

While menopausal and post-menopausal women are at a higher risk of developing uterine cancer, it is crucial to understand that women who don’t belong to any of the risk groups may also be diagnosed with the disease due to other factors such as obesity or hormone therapy for breast cancer.

What are the most common symptoms of uterine cancer?
Abnormal vaginal bleeding, which means bleeding after menopause or between periods, is the most common symptom of uterine cancer. Typically, the bleeding begins as a form of watery blood-streaked discharge that becomes bloodier with the passage of time.

Other signs and symptoms of uterine cancer include:

  • Difficulty or painful sensation while passing urine
  • Pain in the pelvic region
  • Prolonged and heavy episodes of vaginal bleeding
  • Thin and white vaginal discharge
  • Unusual vaginal bleeding
  • Feeling heaviness in the pelvic area

According to experts, a woman who undergoes any of these signs and symptoms should not ignore the condition and seek medical attention immediately. But it is important to note that these symptoms can indicate something more serious or less severe. You should always check with your doctor to know what’s bothering your body.

The good news is that endometrial or uterine cancer is treatable and there are several options for treatment when the diagnosis is made at an early stage. Treatment methods involve radiation therapy, chemotherapy, hormone therapy or surgical removal of the uterus depending on the particular scenario. To conclude, it can be said that being aware of the condition can help you in dealing with it. In case you have a concern or query you can always consult an expert & get answers to your questions!

3535 people found this helpful
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