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Neuroblastoma Tips

All about Neuroblastoma

Dr. Prashant Mehta 91% (32 ratings)
European Society For Medical Oncology certification, DM - Oncology, MD - General Medicine, MBBS, Fellowship in Bone Marrow Transplant
Oncologist, Faridabad
All about Neuroblastoma

Most commonly occurring in children aged 5 or younger, Neuroblastoma is a type of cancer developing from immature nerve cells most often found in and around the adrenal glands. However, it is not limited and can develop in several other areas of the body, like the chest, neck, spine and different areas of the abdomen where nerve cells can be found in clusters.

Symptoms:
Depending upon the area of the body affected, signs and symptoms may include:

1. Neuroblastoma in the abdomen:

  • Abdominal pain
  • Diarrhea, constipation or other changes in bowel movements
  • A lump of mass under the skin which is anything but tender

2. Neuroblastoma in the chest:

  • Chest pain
  • Wheezing
  • Visible changes in the eyes, such as drooping eyelids or unequal pupil size

3. There are other signs and symptoms caused by neuroblastoma. These may include:

  • Lumps of tissue found under the skin
  • Bruise-like dark circles visible around the eyes
  • Fever
  • Proptosis (a condition in which eyeballs seem to protrude from the sockets)
  • Back pain
  • Bone pain
  • Unexplained weight loss

Causes: Neuroblastoma typically originates in neuroblasts. These are immature nerve cells formed by the fetus as part of the development process. Eventually, neuroblasts convert into fibres and nerve cells which then make up the constituents of the adrenal gland. Normally, they either mature or gradually disappear. Others, which neither mature nor disappear, form tumors.

Complications:
A number of problems may result out of neuroblastoma, including:

  1. Metastasis or spread of the cancerous cells
  2. Spinal cord compression
  3. Paraneoplastic symptoms, such as rapid eye movement or difficulty with eye coordination
  4. Abdominal swelling
  5. Diarrhea

Treatment:
Depending on the child's age, the stage of the cancer, or the types of cells involved, the treatment plan varies accordingly:

  1. Surgery - However, this depends on the size and location of the tumor. Tumors growing near vital organs are too risky to remove
  2. Chemotherapy - involves the use of chemotherapy drugs
  3. Radiation therapy - involves high energy beams, like X-rays
  4. Stem cell transplant or autologous stem cell transplant in case of high-risk neuroblastoma
  5. Immunotherapy - involves drugs which stimulate the immune system to destroy cancerous cells
2058 people found this helpful

Cancer In Immature Nerve Cells - Signs You Must Never Ignore!

MBBS, MS - General Surgery, FRCS
Oncologist, Kolkata
Cancer In Immature Nerve Cells - Signs You Must Never Ignore!

Most commonly occurring in children aged 5 or younger, Neuroblastoma is a type of cancer developing from immature nerve cells most often found in and around the adrenal glands. However, it is not limited and can develop in several other areas of the body, like the chest, neck, spine and different areas of the abdomen where nerve cells can be found in clusters.

Symptoms:
Depending upon the area of the body affected, signs and symptoms may include:

1. Neuroblastoma in the abdomen:

  • Abdominal pain
  • Diarrhea, constipation or other changes in bowel movements
  • A lump of mass under the skin which is anything but tender

2. Neuroblastoma in the chest:

  • Chest pain
  • Wheezing
  • Visible changes in the eyes, such as drooping eyelids or unequal pupil size

3. There are other signs and symptoms caused by neuroblastoma. These may include:

  • Lumps of tissue found under the skin
  • Bruise-like dark circles visible around the eyes
  • Fever
  • Proptosis (a condition in which eyeballs seem to protrude from the sockets)
  • Back pain
  • Bone pain
  • Unexplained weight loss

Causes: Neuroblastoma typically originates in neuroblasts. These are immature nerve cells formed by the fetus as part of the development process. Eventually, neuroblasts convert into fibres and nerve cells which then make up the constituents of the adrenal gland. Normally, they either mature or gradually disappear. Others, which neither mature nor disappear, form tumors.

Complications:
A number of problems may result out of neuroblastoma, including:

  1. Metastasis or spread of the cancerous cells
  2. Spinal cord compression
  3. Paraneoplastic symptoms, such as rapid eye movement or difficulty with eye coordination
  4. Abdominal swelling
  5. Diarrhea

Treatment:
Depending on the child's age, the stage of the cancer, or the types of cells involved, the treatment plan varies accordingly:

  1. Surgery - However, this depends on the size and location of the tumor. Tumors growing near vital organs are too risky to remove
  2. Chemotherapy - involves the use of chemotherapy drugs
  3. Radiation therapy - involves high energy beams, like X-rays
  4. Stem cell transplant or autologous stem cell transplant in case of high-risk neuroblastoma
  5. Immunotherapy - involves drugs which stimulate the immune system to destroy cancerous cells

In case you have a concern or query you can always consult an expert & get answers to your questions!

2759 people found this helpful

Cancer Due To Immature Nerve Cells - Complications It Can Cause!

Dr. Mangesh Mekha 90% (32 ratings)
MBBS, MD, DM - Oncology
Oncologist, Pune
Cancer Due To Immature Nerve Cells - Complications It Can Cause!

Most commonly occurring in children aged 5 or younger, Neuroblastoma is a type of cancer developing from immature nerve cells most often found in and around the adrenal glands. However, it is not limited and can develop in several other areas of the body, like the chest, neck, spine and different areas of the abdomen where nerve cells can be found in clusters.

Symptoms:
Depending upon the area of the body affected, signs and symptoms may include:

1. Neuroblastoma in the abdomen:

  • Abdominal pain
  • Diarrhea, constipation or other changes in bowel movements
  • A lump of mass under the skin which is anything but tender

2. Neuroblastoma in the chest:

  • Chest pain
  • Wheezing
  • Visible changes in the eyes, such as drooping eyelids or unequal pupil size

3. There are other signs and symptoms caused by neuroblastoma. These may include:

  • Lumps of tissue found under the skin
  • Bruise-like dark circles visible around the eyes
  • Fever
  • Proptosis (a condition in which eyeballs seem to protrude from the sockets)
  • Back pain
  • Bone pain
  • Unexplained weight loss

Causes: Neuroblastoma typically originates in neuroblasts. These are immature nerve cells formed by the fetus as part of the development process. Eventually, neuroblasts convert into fibres and nerve cells which then make up the constituents of the adrenal gland. Normally, they either mature or gradually disappear. Others, which neither mature nor disappear, form tumors.

Complications:
A number of problems may result out of neuroblastoma, including:

  1. Metastasis or spread of the cancerous cells
  2. Spinal cord compression
  3. Paraneoplastic symptoms, such as rapid eye movement or difficulty with eye coordination
  4. Abdominal swelling
  5. Diarrhea

Treatment:
Depending on the child's age, the stage of the cancer, or the types of cells involved, the treatment plan varies accordingly:

  1. Surgery - However, this depends on the size and location of the tumor. Tumors growing near vital organs are too risky to remove
  2. Chemotherapy - involves the use of chemotherapy drugs
  3. Radiation therapy - involves high energy beams, like X-rays
  4. Stem cell transplant or autologous stem cell transplant in case of high-risk neuroblastoma
  5. Immunotherapy - involves drugs which stimulate the immune system to destroy cancerous cells

In case you have a concern or query you can always consult an expert & get answers to your questions!

1895 people found this helpful

Brain Tumor

Dr. Swarup Kumar Ghosh 89% (82 ratings)
MD - Bio-Chemistry, MF Homeo (London), DHMS (Diploma in Homeopathic Medicine and Surgery), BHMS
Homeopath, Kolkata
Brain Tumor

An organ which regulates all the functions essential for an active life. General symptoms of brain tumor are headache vomiting without nausea. The vision is also affected. Neuroblastoma is the rare lethal cancer of the nervous ststem. It originates in the embryonic neural cells in the neck, chest, abodomen or pelvis. It may be present at birth but may not produce any symptom. Mental changes, dullness, epileptic convulsios & giddiness are other signs. Such tumors do not contain any blood vessls but may produce pain and other sensations.

 Exact cause is not known uptill now. It may be hereditary.
 X - ray pictures:-
air is injecyed into the ventricles prior to the x - ray examinatiion. The examination is known as pneumo - uentriculograpy.

 Nuclear magnetic resonance eeg.

 Biopsy.
 The operation performed on the brain is called craniotomy. During this procedure, a piece of the tumor is growing. Afger the tumor is removed. The piece of bone is usually replaced, except when the brain tissue is very swollen. Most types of brain tumors have a tendency to swell surgical intervention sometimes increases the amount of fiuid in tissues.

Treatment the homeopathicy symptoms/sgis base medicin set.
Cal carb 2c, calc flu 200c, plumbum met 30, 200, scirrhinum 1m, sulp 2c, thuja 2c. And other.
 

2 people found this helpful

Adrenal Gland Cancer - 15 Tell Tale Signs You Must be Aware of

Dr. Anirban Biswas 93% (1277 ratings)
PGP In Diabetologist, Fellowship in Non-Invasive Cardiology, MD - Medicine, MBBS
Endocrinologist, Delhi
Adrenal Gland Cancer - 15 Tell Tale Signs You Must be Aware of

Adrenal gland cancer is a form of cancer which usually affects adrenals (tiny glands which sit above each kidney). The kidneys are situated inside the upper abdomen. The tumor usually develops in the outer part of the adrenal gland called the cortex. These hormones are called steroids and produce cortisol (hormone made in the adrenal gland) and sex hormones. 

Types of Adrenal Tumors:

  1. Cancer in the outer part of the adrenal gland like adrenocortical carcinoma.
  2. Neuroblastoma (usually affects children).
  3. An extremely rare form of tumor called pheochromocytoma.

Symptoms of Adrenal Gland Cancer:

  1. Low levels of potassium
  2. High blood pressure
  3. Panic attacks and anxiety can also occur
  4. Nervousness
  5. Throbbing sensation in the heart
  6. Immense headache
  7. Excessive amount of sweating
  8. Pain in the abdominal area
  9. Extreme fluctuation in blood sugar levels (diabetes)
  10. Weight loss or weight gain for no reason.
  11. Weakness and feelings of fatigue
  12. Hair loss
  13. Some changes in the genitalia.
  14. Unusual occurrence of acne.
  15. Changes in sex drive (libido).

Treatments of Adrenal Gland Cancer:

  1. SurgeryThis option can be considered in extreme cases. Surgery usually involves surgically removing the tumors. If the tumor is smaller than 5 cm, it might not be cancerous or dangerous. In this case a laparoscopic surgery is suggested.
  2. Hormone Therapy: Adrenal glands might produce excess hormones during other treatments for curing adrenal gland cancer. The doctor might suggest drugs like metyrapone, streptozotocin, metyrosine and spironolactone to maintain your hormone levels.
  3. ChemotherapyThis is the most common form of treatment to kill the cancer cells. Chemotherapy stops the cells ability to divide and grow thus destroying the cancer cells. During chemotherapy a patient is given a combination of different drugs at a time. The amount of adrenocorticoids which is produced by the adrenal glands during adrenal cancer is greatly reduced. The side effects of chemotherapy include nausea, vomiting, risk of infection, loss of appetite, hair loss, diarrhea and fatigue. If you wish to discuss any specific problem, you can consult an endocrinologist.
3199 people found this helpful

Bulging Eyes - 10 Things That May Cause It

Dr. Vaibhev Mittal 89% (3433 ratings)
Fellowship In Comprehensive Ophthalmology, DOMS
Ophthalmologist, Sangrur
Bulging Eyes - 10 Things That May Cause It

There is a marked difference between having big eyes and eyes that bulge abnormally. This abnormality should not be confused with having large eyes. Bulging eyes can be defined as eyes where the white of the eyes is visible above the cornea (circular black portion of the eye). Medically, this is referred to as Proptosis or Exophthalmos. 

Eyes protrude from the eye sockets if there is a swelling of muscles, fat or tissue behind the eyes. This is dangerous because it exposes the cornea and makes it difficult for the eyes to stay moist and lubricated. In extreme cases, it can also put the optic nerve under pressure and lead to potential vision loss. This is especially serious if noticed only in one eye. 

An overactive thyroid gland is one of the most common triggers for bulging eyes. Another common cause for bulging eyes is Graves disease. Graves disease is an autoimmune condition that makes the thyroid gland release cells and antibodies that fuse the eye muscles. This can directly trigger the condition by inflaming the tissue around the eye or indirectly trigger the condition as it also causes hyperthyroidism

Other causes for this condition are: 

  1. Any injury that causes bleeding behind the eye 
  2. Vascular Disorders : A build up of blood vessels in the skin or inside the orbit 
  3. Leukemia 
  4. Neuroblastoma or nerve cancer 
  5. Infection

Seeing the white of the eye above the cornea is the most obvious symptom of bulging eyes. Excessive dryness, pain and redness of the eyes are other symptoms of this condition. The patient may also find it difficult to close their eyes completely and have difficulty with eye movements. A doctor may use further blood test and imaging tests to confirm a diagnosis. 

Treatment for bulging eyes depends on the condition triggering it. Usual forms of treatment include: 

  1. Eye drops or artificial tears 
  2. Wearing sunglasses 
  3. Corticosteroids 
  4. Chemotherapy or radiation to treat tumors 
  5. Surgery to repair damaged blood vessels 

In cases where eyes bulge because of Graves disease, the below forms of treatment may also be used: 

  1. Beta blockers 
  2. Anti-thyroid medications 
  3. Removal of the thyroid gland 
  4. Replacement hormones 
  5. Radiation to lower the functioning of the thyroid gland 
  6. Orbital decompression surgery where one or more eye socket walls is removed

If you wish to discuss about any specific problem, you can consult the doctor and ask a free question.

2837 people found this helpful
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