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Multiple Myeloma Health Feed

Multiple Myeloma - Everything About It!

Dr. Mukul Roy 91% (637 ratings)
MBBS, DNB ( Radiation Oncology), Fellowship in Uro Oncology, Fellowship in Brachytherapy
Oncologist, Mumbai
Multiple Myeloma - Everything About It!

Multiple myeloma is a type of blood cancer similar to lymphoma and leukemia. Normally, plasma cells make antibodies which are responsible for fighting off infectious diseases. With multiple myeloma, however, they release too much of a protein known as immunoglobulin. Due to the excess buildup of protein in the body, organ damage occurs. Multiple myeloma cannot be cured, it can only have its progression slowed down. Here is everything you need to know about multiple myeloma:

Causes:
Just like with other forms of cancer, the exact cause of multiple myeloma is not known. However, there are several risk factors which are responsible for increasing your chances of suffering from multiple myeloma.

Risk Factors:

  1. Age: Age poses as one of the most important risk factors. Being over 65 increases your chances of getting multiple myeloma, according to studies.
  2. Race: African-Americans are more likely to get multiple myeloma compared to other races.
  3. Genetics: Multiple myeloma is more likely to happen if a family member has it as well.
  4. Other Diseases: Solitary plasmacytoma, MGUS and other plasma related diseases make you more likely to develop multiple myeloma.

Symptoms: 

Diagnosis: 

Your doctor may test you for multiple myeloma if a blood test reveals:

  1. Too much calcium in your blood (hypercalcemia)
  2. Anemia 
  3. Kidney problems
  4. High protein levels in your blood combined with a low albumin level (globulin gap)

Treatment:

There is no cure for multiple myeloma; however with good treatment you can resume normal activities. Here are the treatment options-

  1. Biological therapy: These are medications given in pill form which enhance the body's immune system; so that it can fight off myeloma cells.
  2. Targeted therapy: Targeted therapy is when cancerous cells are killed by targeting the abnormalities within them. These are given through a vein in your arm.
  3. ChemotherapyChemotherapy kills all the cells which are growing at a rapid rate. These drugs can be given through injection or orally.
  4. Corticosteroids: Corticosteroids are medicines which regulate the immune system by controlling the inflammation in the body. Corticosteroids can be taken in pill form or even through injections.
  5. Stem Cells Transplant: An autologous stem cell transplant is recommended for all eligible and suitable patients of multiple myeloma under 65 yrs of age, who show a good response to initial therapy, as it has been proven to improve survival. 
2773 people found this helpful

Myelopathy - Types, Causes And Symptoms

MS - Orthopaedics, MBBS
Orthopedic Doctor, Dehradun
Myelopathy - Types, Causes And Symptoms

Myelopathy refers to any neurological deficit in the spinal cord. The three most common types of myelopathy are cervical myelopathy, lumbar myelopathy and thoracic myelopathy. Here are the causes and symptoms of myelopathy.

Causes

1. Injury

This is a very common cause of myelopathy. Any type of accident or even a traumatic event can cause myelopathy and perhaps even paralysis.

2. Spinal stenosis

This is a condition in which the spinal cord narrows. It is one of the leading causes of myelopathy.

3. Degenerative disc disorders

As you get older, these get more likely as well as other conditions which affect the spinal column such as osteoporosis.

4. Tumor

It is a little known fact that tumors very often do cause myelopathy.

5. Multiple sclerosis

There are many other diseases which may cause myelopathy and multiple sclerosis is one of them.

Symptoms

There are many indications that you are having a form of myelopathy and should consult a medical expert. Here are some of them :

1. Changes in coordination

What this means is that all of a sudden you may find it harder to move certain limbs the way you want to. Sometimes, this can affect the whole body.

2. Sudden muscle weakness

It is highly likely that if you have myelopathy then you will have sudden weakness in your muscles.

3. Decreased hand-eye coordination

This is perhaps the biggest indicator of myelopathy since hand eye coordination is directly linked to your spinal cord and brain and if they are not functioning properly then hand-eye coordination will be worse.

These are just some of the symptoms of myelopathy, however the doctor cannot diagnose myelopathy until he does certain tests. These tests include MRI scans and other tests as well as a regular physical check-up in addition to a look at your medical history.

 

4737 people found this helpful

Hi, My husband was detected with multiple myeloma after 4 cycle of chemotherapy. He under went bone marrow transplant. For 3 years he is under maintenance. Borviz 2 mg injected twice a month. I want to know for how many years borviz can be continued.

MBBS, MD - General Medicine, DM - Medical Oncology
Oncologist, Mumbai
Actually the data is for 2 years for the bortezomib maintenance post bone marrow transplant. However it may be continued if there is no toxicity due to same. So would request to discuss with the physician and if there is no toxicity it may be prudent to continue the same. The expected toxicity would be sensory neuropathy.
2 people found this helpful
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Myelopathy - Know Signs Of It!

Dr. Kedar Agrawal 86% (17 ratings)
MBBS, MS - Orthopaedics
Orthopedic Doctor, Raipur
Myelopathy - Know Signs Of It!

Myelopathy refers to any neurological deficit in the spinal cord. The three most common types of myelopathy are cervical myelopathy, lumbar myelopathy and thoracic myelopathy.

Here are the causes and symptoms of myelopathy.

Causes

1.  Injury
This is a very common cause of myelopathy. Any type of accident or even a traumatic event can cause myelopathy and perhaps even paralysis.

2.  Spinal stenosis
This is a condition in which the spinal cord narrows. It is one of the leading causes of myelopathy.

3. Degenerative disc disorders
As you get older, these get more likely as well as other conditions which affect the spinal column such as osteoporosis.

4.  Tumor
It is a little known fact that tumors very often do cause myelopathy.

5. Multiple sclerosis
There are many other diseases which may cause myelopathy and multiple sclerosis is one of them.

Symptoms

There are many indications that you are having a form of myelopathy and should consult a medical expert. Here are some of them.

1. Changes in coordination
What this means is that all of a sudden you may find it harder to move certain limbs the way you want to. Sometimes, this can affect the whole body.

2. Sudden muscle weakness
It is highly likely that if you have myelopathy then you will have sudden weakness in your muscles.

3. Decreased hand-eye coordination
This is perhaps the biggest indicator of myelopathy since hand eye coordination is directly linked to your spinal cord and brain and if they are not functioning properly then hand-eye coordination will be worse.

These are just some of the symptoms of myelopathy, however the doctor cannot diagnose myelopathy until he does certain tests. These tests include MRI scans and other tests as well as a regular physical check-up in addition to a look at your medical history.

4393 people found this helpful

My mother is suffering from multiple myeloma with acute low sodium level. She is 89 years old. Does Amlo 5 mg will reduce her Sodium level further?

Dr. Monish De 89% (68 ratings)
MBBS, Post Graduate Diploma In Medicine, Fellowship In Medical Oncology
Oncologist, Kolkata
Hi Lybrate User Amlo 5 mg which has amlodipine causes low sodium level in blood. I will advise you to change your drug from amlo to betablocker like nicardia For exact dosing you can contact me.
2 people found this helpful
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All About Multiple Myeloma

Dr. Prashant Mehta 92% (35 ratings)
European Society For Medical Oncology certification, DM - Oncology, MD - General Medicine, MBBS, Fellowship in Bone Marrow Transplant
Oncologist, Faridabad
All About Multiple Myeloma

Multiple myeloma is a type of blood cancer similar to lymphoma and leukemia. Normally, plasma cells make antibodies which are responsible for fighting off infectious diseases. With multiple myeloma, however, they release too much of a protein known as immunoglobulin. Due to the excess buildup of protein in the body, organ damage occurs. Multiple myeloma cannot be cured, it can only have its progression slowed down. Here is everything you need to know about multiple myeloma:

Causes:
Just like with other forms of cancer, the exact cause of multiple myeloma is not known. However, there are several risk factors which are responsible for increasing your chances of suffering from multiple myeloma.

Risk Factors:

  1. Age: Age poses as one of the most important risk factors. Being over 65 increases your chances of getting multiple myeloma, according to studies.
  2. Race: African-Americans are more likely to get multiple myeloma compared to other races.
  3. Genetics: Multiple myeloma is more likely to happen if a family member has it as well.
  4. Other Diseases: Solitary plasmacytoma, MGUS and other plasma related diseases make you more likely to develop multiple myeloma.

Symptoms: 

Diagnosis: 

Your doctor may test you for multiple myeloma if a blood test reveals:

  1. Too much calcium in your blood (hypercalcemia)
  2. Anemia 
  3. Kidney problems
  4. High protein levels in your blood combined with a low albumin level (globulin gap)

Treatment:

There is no cure for multiple myeloma; however with good treatment you can resume normal activities. Here are the treatment options-

  1. Biological therapy: These are medications given in pill form which enhance the body's immune system; so that it can fight off myeloma cells.
  2. Targeted therapy: Targeted therapy is when cancerous cells are killed by targeting the abnormalities within them. These are given through a vein in your arm.
  3. ChemotherapyChemotherapy kills all the cells which are growing at a rapid rate. These drugs can be given through injection or orally.
  4. Corticosteroids: Corticosteroids are medicines which regulate the immune system by controlling the inflammation in the body. Corticosteroids can be taken in pill form or even through injections.
  5. Stem Cells Transplant: An autologous stem cell transplant is recommended for all eligible and suitable patients of multiple myeloma under 65 yrs of age, who show a good response to initial therapy, as it has been proven to improve survival. In case you have a concern or query you can always consult an expert & get answers to your questions!
2125 people found this helpful

What is the best diet for multiple myeloma patient whose bones are week hemoglobin is down & now effecting in kidneys creatinine levels is quite high it is 2+ so which foodgrains, fruits & dry fruits to avoid which should be taken as diet?

Dr. Surbhi Agrawal 92% (20008 ratings)
PDDM, MHA, MBBS
General Physician, Nashik
Eat a high-fiber diet. Get insoluble and soluble fiber. Limit foods that are high in fat. Choose lean meats. Incorporate probiotics into your diet. Eat on schedule. Stay hydrated.
2 people found this helpful
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My mother is a multiple myeloma patient and is not taking any medicines now after 3 years of VAD treatment and regular checkup. She complains of twisting and tightness in toes and finger joints nowadays. I think it's side effect of chemo that was done. Any suggestions?

Dr. P Nagaraj 89% (3802 ratings)
FRHS, Ph.D Neuro , MPT - Neurology Physiotherapy, D.Sp.Med, DPHM (Health Management ), BPTh/BPT
Physiotherapist, Chennai
My mother is a multiple myeloma patient and is not taking any medicines now after 3 years of VAD treatment and regula...
Do Take IFT and laser Therapy for pain relief for 10 days followed by mobilisation exercise from physiotherapist Best wishes.
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He is having severe back pain .our doctor suggested that to take biopsy and bone marrow by that result they said that he have multiple myeloma so what is the best treatment for that.

Dr. Sanjay Sharma 89% (304 ratings)
Fellowship in Interventional Pain management , Diploma in Anesthesia, DA, MBBS
Pain Management Specialist, Jaipur
He is having severe back pain .our doctor suggested that to take biopsy and bone marrow by that result they said that...
Madam for said problem, you are advised to get in regular touch with oncologist as an expert. Otherwise no one has right to say about unwanted opinion.
6 people found this helpful
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