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Merkel Cell Carcinoma Tips

Renal Cell Carcinoma - How It Can Be Managed?

MD, MBBS
Oncologist, Ernakulam
Renal Cell Carcinoma - How It Can Be Managed?

Patients with metastatic renal cell carcinoma (RCC) to the brain have a very poor prognosis of three months if left untreated. SRS is an effective treatment modality in numerous patients. This case exemplifies the utility of stereotactic radiosurgery (SRS) in prolonging survival and maintaining quality of life in a patient with RCC. 

  • This 64-year-old female patient initially presented to her primary care physician 22 months after a left nephrectomy for RCC with complaints of mild, intermittent headaches and difficulty with balance. An MRI revealed five cerebellar lesions suspicious for intracranial metastasis. The patient's first GKRS treatment targeted four lesions with 22 Gy at the 50% isodose line. She underwent a total of seven GKRS treatments over the next 60 months for recurrent metastases to the brain. 
  • 72 months and 12 months have now passed since her brain metastases were first discovered and since her last GKRS treatment, respectively, and this woman is alive with considerable quality of life and no evidence of metastatic reoccurrence. This case shows that repeated GKRS treatments, with minimal surgical intervention, can effectively treat multiple intracranial lesions in select patients, prolonging survival and avoiding iatrogenic neurocognitive decline while maintaining a high quality of life.

In case you have a concern or query you can always consult an expert & get answers to your questions!

3405 people found this helpful

Risk Factors For Renal Cell Carcinoma

Dr. Veda Padma Priya 86% (46 ratings)
MBBS, DNB (Surgical Oncology), MS - General Surgery
Oncologist, Delhi
Risk Factors For Renal Cell Carcinoma

Renal cell carcinoma is the most common type of kidney cancer and accounts for 90 percent of all kidney cancers. Young children can develop another kind of kidney cancer termed as Wilms’ tumour. According to a study conducted by the World Health Organization (WHO), renal cell carcinoma has increased manifold over the past decade. The primary reason is the improvement of imaging techniques and the lack of healthy lifestyle practices by most adults. 

Possible Causes of Renal Cell 
Carcinoma There is still no conclusive evidence reported by any scientist about the exact cause of renal cell carcinoma. What doctors do know is the fact the introduction of renal cell carcinoma triggers when few cells of the kidney acquire a mutation in the DNA of a person. Mutation communicates the cell to divide and grow uncontrollably. This leads to an accumulation of cells that eventually forms one or multiple tumours and grows beyond the kidney. 

Risk Factors For Renal Cell Carcinoma 
Some of the common risk factors for renal cell carcinoma include the following: 

Typical Symptoms of Renal Cell 
Carcinoma Renal cell carcinoma is hard to detect in its early stages. There is no routine test either that can readily diagnose this condition. However, certain symptoms such as blood in urine, fatigue, sudden loss of appetite, fluctuation of fever, pain in the shoulder or back area, sudden weight loss etc. can indicate renal cell carcinoma. 

Feasible Treatment 
Options for Renal Cell Carcinoma Most renal cell carcinoma is treated with surgery. There are several types of surgeries, and depending on the stage and spread of cancer, one of the types is opted for. 

  1. Nephrectomy- This is a type of surgery that involves removing the entire kidney, some healthy tissues at the border, and other tissues such as adrenal gland, lymph nodes etc. The surgeon might perform an open or laparoscopic nephrectomy. 
  2. Partial nephrectomy– Under this type of surgery, the surgeon removes a tumour and a part of the healthy tissue from the border of the kidney. This form of surgery can be done via a robotic, laparoscopic or open procedure. 
  3. Cryoablation- This is a non-surgical method of treating renal cell carcinoma. Here, a needle is inserted into the kidney using image guidance, ultrasound, and cold gas. It freezes the cancer cells and limits their growth. 

Apart from these, some other methods to counter advanced or recurring kidney cancer include targeted therapy, radiation therapy, biological therapy, partial surgery of the kidney, clinical trials etc.

In case you have a concern or query you can always consult an expert & get answers to your questions!

2721 people found this helpful

Causes, Symptoms And Treatment For Renal Cell Carcinoma

Dr. Premitha R 89% (60 ratings)
MBBS Bachelor of Medicine and Bachelor of Surgery, Diploma In Medical Radio Therapy, DNB
Oncologist, Bangalore
Causes, Symptoms And Treatment For Renal Cell Carcinoma

Renal cell carcinoma is the most common type of kidney cancer and accounts for 90 percent of all kidney cancers. Young children can develop another kind of kidney cancer termed as Wilms’ tumour. According to a study conducted by the World Health Organization (WHO), 20qw revealed that renal cell carcinoma has increased manifold over the past decade. The primary reason is the improvement of imaging techniques and the lack of healthy lifestyle practices by most adults.

Possible Causes of Renal Cell Carcinoma
There is still no conclusive evidence reported by any scientist about the exact cause of renal cell carcinoma. What doctors do know is the fact the introduction of renal cell carcinoma triggers when few cells of the kidney acquire a mutation in the DNA of a person. Mutation communicates the cell to divide and grow uncontrollably. This leads to an accumulation of cells that eventually forms one or multiple tumours and grows beyond the kidney.

Risk Factors For Renal Cell Carcinoma
Some of the common risk factors for renal cell carcinoma include the following:

  1. Old age
  2. Persistent smoking
  3. Exposure to substances such as herbicide, cadmium etc.
  4. A family history of renal carcinoma
  5. Hypertension
  6. Inherited syndrome such as Hippel-Lindau disease, tuberous sclerosis complex, Birt-Hogg-Dube syndrome etc.
  7. Obesity
  8. An existing case of kidney failure

Typical Symptoms of Renal Cell Carcinoma
Renal cell carcinoma is hard to detect in its early stages. There is no routine test either that can readily diagnose this condition. However, certain symptoms such as blood in urine, fatigue, sudden loss of appetite, fluctuation of fever, pain in the shoulder or back area, sudden weight loss etc. can indicate renal cell carcinoma.

Feasible Treatment Options for Renal Cell Carcinoma
Most renal cell carcinoma is treated with surgery. There are several types of surgeries, and depending on the stage and spread of cancer, one of the types is opted for.

  1. Nephrectomy- This is a type of surgery that involves removing the entire kidney, some healthy tissues at the border, and other tissues such as adrenal gland, lymph nodes etc. The surgeon might perform an open or laparoscopic nephrectomy.
  2. Partial nephrectomy– Under this type of surgery, the surgeon removes a tumour and a part of the healthy tissue from the border of the kidney. This form of surgery can be done via a robotic, laparoscopic or open procedure.
  3. Cryoablation- This is a non-surgical method of treating renal cell carcinoma. Here, a needle is inserted into the kidney using image guidance, ultrasound, and cold gas. It freezes the cancer cells and limits their growth.

Apart from these, some other methods to counter advanced or recurring kidney cancer include targeted therapy, radiation therapy, biological therapy, partial surgery of the kidney, clinical trials etc. In case you have a concern or query you can always consult an expert & get answers to your questions!

1839 people found this helpful

Renal Cell Carcinoma - Causes, Symptoms and Treatment

Dr. Sajjan Rajpurohit 85% (37 ratings)
MBBS, MD - Oncology, DNB - Super Speciality, Immuno Oncology
Oncologist, Delhi
Renal Cell Carcinoma - Causes, Symptoms and Treatment

Renal cell carcinoma is the most common type of kidney cancer and accounts for 90 percent of all kidney cancers. Young children can develop another kind of kidney cancer termed as Wilms’ tumour. According to a study conducted by the World Health Organization (WHO), 20qw revealed that renal cell carcinoma has increased manifold over the past decade. The primary reason is the improvement of imaging techniques and the lack of healthy lifestyle practices by most adults.

Possible Causes of Renal Cell Carcinoma
There is still no conclusive evidence reported by any scientist about the exact cause of renal cell carcinoma. What doctors do know is the fact the introduction of renal cell carcinoma triggers when few cells of the kidney acquire a mutation in the DNA of a person. Mutation communicates the cell to divide and grow uncontrollably. This leads to an accumulation of cells that eventually forms one or multiple tumours and grows beyond the kidney.

Risk Factors For Renal Cell Carcinoma
Some of the common risk factors for renal cell carcinoma include the following:

  1. Old age
  2. Persistent smoking
  3. Exposure to substances such as herbicide, cadmium etc.
  4. A family history of renal carcinoma
  5. Hypertension
  6. Inherited syndrome such as Hippel-Lindau disease, tuberous sclerosis complex, Birt-Hogg-Dube syndrome etc.
  7. Obesity
  8. An existing case of kidney failure

Typical Symptoms of Renal Cell Carcinoma
Renal cell carcinoma is hard to detect in its early stages. There is no routine test either that can readily diagnose this condition. However, certain symptoms such as blood in urine, fatigue, sudden loss of appetite, fluctuation of fever, pain in the shoulder or back area, sudden weight loss etc. can indicate renal cell carcinoma.

Feasible Treatment Options for Renal Cell Carcinoma
Most renal cell carcinoma is treated with surgery. There are several types of surgeries, and depending on the stage and spread of cancer, one of the types is opted for.

  1. Nephrectomy- This is a type of surgery that involves removing the entire kidney, some healthy tissues at the border, and other tissues such as adrenal gland, lymph nodes etc. The surgeon might perform an open or laparoscopic nephrectomy.
  2. Partial nephrectomy– Under this type of surgery, the surgeon removes a tumour and a part of the healthy tissue from the border of the kidney. This form of surgery can be done via a robotic, laparoscopic or open procedure.
  3. Cryoablation- This is a non-surgical method of treating renal cell carcinoma. Here, a needle is inserted into the kidney using image guidance, ultrasound, and cold gas. It freezes the cancer cells and limits their growth.

Apart from these, some other methods to counter advanced or recurring kidney cancer include targeted therapy, radiation therapy, biological therapy, partial surgery of the kidney, clinical trials etc.

In case you have a concern or query you can always consult an expert & get answers to your questions!

4320 people found this helpful

Super Fact of the Day: Your cells can self-destruct!

Dr. S K Mittal 88% (3678 ratings)
MBBS
General Physician, Faridabad
Super Fact of the Day: Your cells can self-destruct!
If a cell is damaged or if it acquires some kind of infection, it has the ability to commit suicide by a process called apoptosis. This works to ensure proper development by keeping the body's process of mitosis in check. A cell's inability to experience apoptosis can result in the advancement of cancer.

Would you like to share this interesting fact with family or friends? go ahead and share!
493 people found this helpful

How Good Is The Stem Cell Facelift?

Dr. Pk Talwar 89% (152 ratings)
FAPS (Cosmetic Surgery)-USA,, M.Ch - Plastic Surgery, MS - General Surgery, MBBS
Cosmetic/Plastic Surgeon, Delhi
How Good Is The Stem Cell Facelift?

A stem cell facelift includes face grafting. It is used for removing the unwanted and extra fat from an area of the body and then transfers it to the face. The fat in our body contains naturally regenerative cells. These also include blood vessel producing cells, adult stem cells and growth-secreting cells. With this facelift, the person’s own cells are infused into their superficial muscular aponeurotic system (SMAS) as well as under the facial muscles. When these meet with the aged facial tissues, they generate new and healthy tissues that give you rejuvenated skin. 

Here is how this treatment is a great procedure: 

  1. Eliminates Loose Skin: This procedure tends to reposition the patient’s tissues by adding volume and stretching skin.. 
  2. A Better Body Contour: This procedure starts with a gentle liposuction technique. It removes the unwanted fat from different parts of the body. However, the procedure only targets the stubborn fat that cannot be burnt. This is usually present in the belly, abdomen, hips or thighs. This helps the body in both ways and makes the body appear more slender. 
  3. A More Volumized Skin: The fat that is injected, pumps the skin, making it look more youthful. It fills the hollow areas and rejuvenates the wrinkles and fat lines, giving your skin a more youthful and smooth appearance. 
  4. Natural Looking Results: The treatment does not make a person’s face look artificial or out of place. It only remodels it in a natural way. The previous surgical techniques used to cut the skin, pull it tight ,therefore it used to appear artificial and plastic-like. With the stem cell facelift, a lot of volumes is added to the skin however, it fits the hollow areas and the wrinkles are smoothened but the skin is not pulled as tightly as before. It makes your skin look youthful and plump. 
  5. Less Bruising and Faster Recovery: The conventional facelift methods use scissors and scalpels and it can cause a lot of bruising and bleeding. This stem cell treatment, however, uses an electric knife and it stops the bleeding and cuts. It also helps in a faster recovery. 
  6. Customized Treatment: Unlike the conventional methods, this treatment can be customized according to a patient’s need and medical history. Only the areas they need should be rejuvenated, are treated. 

A stem cell facelift is obviously better than other facelifts. However, surgeons these days only operate on specific cases where it is genuinely required and not just for simple beautification reasons the same. Procedures like this might cause a lot of money hence; the requirements should be taken into account accordingly. If you wish to discuss about any specific problem, you can consult a Cosmetic/Plastic Surgeon.

2166 people found this helpful

Cell Active Therapy For Hair Growth!

Dermatologist
Dermatologist, Delhi
Cell Active Therapy For Hair Growth!

Whether you’re a man or a woman, whether you have long tresses or a short crop, no one likes the thought of going bald. Hair loss can be caused by a number of factors. It may be in your genes, it could be because of your lifestyle or it could even be the result of hormonal changes. Thankfully, you don’t have to just sit back and watch yourself grow bald, you can treat it.

Cell active therapy is a form of treatment that is aimed at boosting new hair growth. This can be used to treat receding hairline, bald patches, thinning hair and alopecia. Cell active therapy is called so because it activates cells in the scalp and hair follicles by stimulating blood circulation. As the hair follicles are energized, new hair growth is triggered. It also stimulates collagen production that improves skin tone and elasticity. Cell active therapy does not require hospitalization of any kind. All you need is a dermaroller.

What is a dermaroller?

A dermaroller is a simple device that looks a lot like a round bristled brush on a long handle. Instead of bristles to untangle your hair, this has metal pins that can make tiny pinpricks on your scalp. The width of a dermaroller ranges from 0.25mm to 0.5mm with the latter being more popular. This penetrates only as far as your dermal layer to stimulate blood circulation and new cell production. Using a dermaroller is relatively painless.

Using the dermaroller

Before you use a dermaroller, it is essential to clean your scalp properly and clean the dermaroller. The dermaroller must be sanitized with boiling hot water each time it is used to reduce the chances of infection. If you already have a scalp infection, do not use a dermaroller until the infection clears up. Once the dermaroller has cooled down; run it over the bald areas of your scalp. You will need to apply a light pressure so as to allow the pins to penetrate your scalp without drawing blood.

A dermaroller can be used indefinitely, but you should start seeing an improvement in your hair growth quite soon.

In case you have a concern or query you can always consult an expert & get answers to your questions!

4889 people found this helpful

Cell Phone And Neck Pain

Dr. Siva Prasad 92% (937 ratings)
MBBS ,MD
Pain Management Specialist, Hyderabad
Cell Phone And Neck Pain

One should note continuous smart phone usage more than 15 min at a time increases strain on neck muscles and spinal cord.

More muscle spasm becomes irreversible and turns into chronic pain in the neck which can be debilitating.

Do yoga and exercise daily and be healthy

Causes And Prognosis Of Giant Cell Tumours!

MBBS, MS - Orthopaedics
Orthopedist, Chennai
Causes And Prognosis Of Giant Cell Tumours!

Rare forms of bone oriented tumours are giant cell tumours, which are mostly found in the bones that are long. This tumour is mostly found in young people between the age of 25 to 40 years and is more common in women than in men. The slow progressive growth of this tumour is more like a lesion rather than a mass, and it causes significant pain. It can also lead to bone destruction. Let us find out the various facets of these tumours including causes, diagnosis, treatment and prognosis.

  • Causes: The actual cause of this condition is not yet known, although many orthopaedic specialists tend to associate it with Paget disease, which is a chronic bone disorder. The main symptoms of this disease include enlargement and deformity of the bones. Giant cell tumours are not associated with injuries, genetics or environmental factors. 
  • Symptoms: There are many symptoms that can point at the presence of the giant cell tumour. These include pain in the joints surrounding the bone on which the tumour is growing. Also, inflammation and fractures might be caused due to this growth. The surrounding joints may face difficulty as far as movement goes, and fluid retention might also take place.
  • Diagnosis: The diagnosis of the condition is usually done by an orthopaedic specialist who will conduct an x-Ray to study the area surrounding the bone. This will help in throwing up images of the tissue, bones and other organs in the area. The doctor may also carry out a biopsy during which tissue samples will be procured for further examination under a microscope, so as to determine whether or not the growth is a malignant one. Also, radionuclide bone scans may be conducted to find out if there is any bone change due to other bone diseases and this tumour.
  • Treatment: The treatment of this condition will depend largely on the patient's age and medical history where the doctor may take stock of any other ailments and diseases which may or may not interfere with the chosen path of treatment. One of the ways of treating this condition is with surgery that will help in removing the damaged bone. In very severe cases, amputation may also be required. Further, bone reconstruction surgery can also be followed for treatment.
  • Prognosis: Local recurrence is a risk as far as giant cell tumours are concerned. A CT scan of the chest, abdomen and pelvic area should be carried out in a routine manner for at least two years after treatment. If you wish to discuss about any specific problem, you can consult an Orthopaedist.

 

4312 people found this helpful

How Good Is The Stem Cell Face Lift?

Dr. Ashish Khare 86% (10 ratings)
MCh - Plastic and Reconstructive Surgery, MBBS, MS - General Surgery, Fellowship Reconstructive Microsurgery
Cosmetic/Plastic Surgeon, Gurgaon
How Good Is The Stem Cell Face Lift?

The skin is constantly exposed to sun and multiple environmental pollutants, causing a lot of degeneration. The face, being the most exposed part, bears the brunt of this. A number of dark spots, wrinkles, sagging, fine lines, etc. appear as a result of ageing and become very prominent on the face. Not just are these cosmetic concerns, but they also affect the person’s morale.

Origin:
The body has millions of types of cells, but there are some known as stem cells which are totipotent the ability to transform into any type of cell (blood, bone, muscle, skin, etc.) These totipotent stem cells were used earlier in treating sports injuries to repair joints and ligaments. They are present in large numbers in fat and so the affected joint would be injected with fat, and the stem cells from here would help in regeneration of the joint. The same concept was extended by cosmetic surgeons to treat facial ageing problems. Fat extracted from an area (usually abdomen or inner thigh) is injected into predetermined areas on the face. These then act as fillers and help in skin rejuvenation and repair.

Procedure:

  1. Case selection with both the doctor and the patient.
  2. Setting realistic expectations is very important
  3. The area selected for fat extraction is injected with local anaesthesia
  4. The excess oil and blood from this extract is removed by blotting
  5. It is then mixed with growth factors, which are embedded in beads of hyaluronic acid, which allows for prolonged and constant release of growth factors
  6. After thorough mixing, this is then injected into specific areas on the face in multiple planes – usually three, from the innermost to the outermost layers of the skin
  7. The growth factors used for each of these layers also could differ. The second layer could have more of protein (collagen) as it helps in keeping the skin firm.
  8. The topmost layer could have more of blood cells as it is involved in vascular supply
  9. After this, a final resurfacing is done to ensure the fine lines and superficial skin damage is repaired
  10. The face may also be sculpted in specific areas to correct additional features, like the jawline
  11. Fat deposit correction (some addition, some removal) may also be done.

Advantages:

  1. No surgical incision required, only needle incisions to extract and infuse fat cells
  2. Faster healing
  3. Done as outpatient procedure
  4. No hospitalization
  5. No anaesthetic required
  6. No scar, as the fat is used from lesser visible areas like inner thighs
  7. Quicker and remarkable results
  8. Complete facial rejuvenation
  9. Can be done from patient’s own blood or from a donor

In case you have a concern or query you can always consult an expert & get answers to your questions!

3523 people found this helpful
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