Lybrate Logo
Get the App
For Doctors
Login/Sign-up
Book Appointment
Treatment
Ask a Question
Plan my Surgery
Health Feed
tab_logos
Health Feed
tab_logos
Find Doctors
tab_logos
Health Packages
AllQ&AsTipsQuizzes
Facebook Icon
Twitter Icon
Telegram Icon
Linkedin Icon

Hyperkalemic Periodic Paralysis Health Feed

Last Updated: 7 years ago• Featured Tip
Share
Bookmark
Report
Profile Image

MPT - Orthopedic Physiotherapy, BPTh/BPT...read more

Physiotherapist•Noida
banner-image
Physiotherapy and sleep paralysis have a deep connection when you have to treat sleep paralyses the intelligent way. To discover the benefits of physiotherapy in healing sleep paralysis, let's get a clear understanding of sleep paralyses first, and then the role of physiotherapy.

What is sleep paralysis and common causes?

Sleep paralysis is a sleeping disorder. Its symptoms are that you suddenly feel in the middle of the night or in mid sleep that you can't move, react, talk, ...more
Asked for male, 35 years old from South Goa
Share
Bookmark
Report

My father (age 56 years & weight 70 Kg) has been diagnosed with Non-Small Cell Lung Cancer, Stage 4 with primary tumour in his Left Upper Lobe and metastasis in Liver and Bone. The biopsy report has confirmed it to be adenocarcinoma. The cancer was detected while he was admitted at a hospital in Mumbai and was undergoing treatment for Acute Paraplegia which happened on 02 Nov 16, due to arteries-Venous Fistula at D-10 level resulting in oedema/ ischemia of the spine from D-5 to Conus. After two failed attempts of embolization, towards treatment of the AVF, surgical clipping of the fistula was undertaken on 10 Nov 16. As part of post-operative rehabilitation therapy for his paraplegia, he was given 65 session of Hyper-basic Oxygen Therapy at 2.4 ata pressure for about two and a half month and about two hour of Physiotherapy for the same duration. My father was recovering well and had started walking with the help of support (walker). MRI of the spine taken in mid Jan & Mid June 2017 indicates that the spinal cord oedema had improved significantly, although atrophy of the spine cord is still present. He complained of wheezing and breathing difficulty and towards ascertaining the cause a X-ray was taken on 23 Feb 17 which showed massive pleural effusion in his left lungs. A series of tests followed with the ultimate result as NSCLC Stage 3B. It was categorised as Stage 3B as the pleural effusion was para-malignant and no metastases was noted in any other body parts. He was started with CCRT treatment which concluded on 05 May 17. During the treatment he was given daily dose of radiation therapy to his primary tumour site in his left upper lobe using IGRT (60 Gy/ 30 #/6 weeks) and weekly chemotherapy with paclitaxel (150 mg) & Carboplatin (300 mg) for 6 weeks. Despite the treatment, the cancer is advancing and has now spread to Liver and Bones as brought out in his latest PET CT report. Lung tissue which was obtained during CT guided biopsy conducted in the month of Mar 17, before the CCRT treatment was started, has tested positive for EGFR mutation – “E746_A750del is detected in EXON 19 of EGFR gene”. His doctor has started my father on Erlotinib 150 mg OD since 26 Jun 17. My father has developed Post Obstructive Pneumonia in his left lung and there is consolidation in his entire left lung. This is evident from a recent X-ray. He is having difficulty in breathing, takes short & fast breath, sweats a lot, feels cold, has irritation in his throat and gets tired very fast. He also has issue eating solid food and had greatly cut down his diet. He was started on Oral antibiotic for a week, but did not respond to it. He is admitted in the hospital and is being injected with antibiotics through IVs and injections. His condition remains to be same with no much improvement. His SPO2 level is also low at 90-92%. My father also has severe lower back pain and has also been diagnosed with progressive paraparesis. Because of the back pain he is not able to lie down on his back. A recent screening of the entire spine has confirmed that there is no evident compression of the spinal cord but clearly shows a number of metastasis in the vertebrae (Clivus, Dv2, Lv2, Lv4 & Tail Bone). There are plans to start him on Radiation Therapy for his spine. Is this:- 1.The right therapy for him? 2.What other option do we have for treating his spinal mets? 3.Can Radiation to treat his mets in the vertebra, damage his spine and cause further paraparesis? 4.Could you please suggest anything towards treatment of my father?

Profile Image

DM - Oncology, MD - Internal Medicine

Oncologist•Noida
If there is localized backache than radiation treatment may be the right choice for the time being. Though it won't cure lung cancer. It may help in resolving the local pain. Patient is on erlotinib since 26-6-17. The medicine should have shown some benefit by now. Continue it for another one month. It may be stopped for the time /days spinal radiation is given by your treating doctor. Add bisphosphonates taking care of creatinine and calcium levels. Ask for appropriate amount of analgesics. Giv...more
Asked for male, 57 years old from Mumbai
Share
Bookmark
Report

My father has been diagnosed with Non-Small Cell Lung Cancer, Stage 4 with primary tumour in his Left Upper Lung and metastasis in Liver and Bone. The biopsy report has confirmed it to be adenocarcinoma. The cancer was detected while he was admitted at a hospital in Mumbai and was undergoing treatment for Acute Paraplegia which happened on 02 Nov 16, due to arteries-Venous Fistula at D-10 level resulting in oedema/ ischemia of the spine from D-5 to Conus. After two failed attempts of embolization, towards treatment of the AVF, surgical clipping of the fistula was undertaken on 10 Nov 16. As part of post-operative rehabilitation therapy for his paraplegia, he was given 65 session of Hyper-basic Oxygen Therapy at 2.4 ata pressure for about two and a half month and about two hour of Physiotherapy for the same duration. My father was recovering well and had started walking with the help of support (walker). MRI of the spine taken in mid Jan & Mid June 2017 indicates that the spinal cord oedema had improved significantly, although atrophy of the spine cord is still present. He complained of wheezing and breathing difficulty and towards ascertaining the cause a X-ray was taken on 23 Feb 17 which showed massive pleural effusion in his left lungs. A series of tests followed with the ultimate result as NSCLC Stage 3B. He was started with CCRT treatment which concluded on 05 May 17. During the treatment he was given daily dose of radiation therapy using IGRT (60 Gy/ 30 #/6 weeks) and weekly chemotherapy with paclitaxel (150 mg) & Carboplatin (300 mg) for 6 weeks. Despite the treatment, the cancer is advancing and has now spread to Liver and Bones as brought out in his latest PET CT report. Lung tissue which was obtained during CT guided biopsy conducted in the month of Mar 17, before the CCRT treatment was started, has tested positive for EGFR mutation – “E746_A750del is detected in EXON 19 of EGFR gene”. The medicine oncologist has however said that the gene profiling of the primary tumour tissue is not sufficient for starting Targeted Therapy and gene profiling of a tissue obtained from any of the metastatic site is necessary for the same. Three procedures have been undertaken to obtain tissue sample from the metastases site, twice from the liver and once from the pleural deposits, and all the three times the cancerous tissue could not be obtained. Due to non-availability of conformed cancerous tissue from the metastases site, a firm treatment plan has yet not been made for my father. In the meantime, the doctor has recently started my father on Erlotinib 150 mg OD as there has been considerable delay in his next phase of treatment due to non availability of metastases cancerous tissue. Could you please help me by answering the following:- 1.Can you suggest anything towards treatment of my father? 2.Is gene profiling of tissue from a metastases site absolutely necessary for starting targeted therapy for my father? 3.I read online that Erlotinib or Afatinib can be used as Targeted Therapy for patient with EGFR Lung cancer mutation. Is this true? If yes, will a daily tablet of these drugs be sufficient for his next phase of treatment, or a concurrent conventional chemotherapy is also required? 4.Can 65 session of Hyper-basic Oxygen Therapy at 2.4 ata given at a stretch of about 80 days, with a daily dose of 02 hour be a cause of his cancer? I have read it online that the oxygen free radical produced during HBOT treatment can cause cancer.

Profile Image

MS, DNB (Surgical Oncology)

Oncologist•Jodhpur
Hi lybrate-user, You summarize the case very well. I understanding of your case says, he has Ca lung adenoca, treated with dCTRT, that progressed and now disseminated disease, which is not curable by any means. The goal of the treatment in such cases would be palliative only, which means to increase longevity without causing much side effects of the drugs and reduce his problem. Now going towards your questions, 1&2. At this juncture, Gene profiling is not necessary for me but to start the EGFR ...more
Last Updated: 8 years ago• Featured Tip
Share
Bookmark
Report
Profile Image

mpt

Physiotherapist•Ahmedabad
banner-image
Physiotherapy and sleep paralysis have a deep connection when you have to treat sleep paralyses the intelligent way. To discover the benefits of physiotherapy in healing sleep paralysis, let's get a clear understanding of sleep paralyses first, and then the role of physiotherapy.

What is sleep paralysis and common causes?

Sleep paralysis is a sleeping disorder. Its symptoms are that you suddenly feel in the middle of the night or in mid sleep that you can't move, react, talk, ...more
Last Updated: 8 years ago• Featured Tip
Share
Bookmark
Report
Profile Image

MPT - Orthopedic Physiotherapy, BPTh/BPT...read more

Physiotherapist•Noida
banner-image
A spinal cord injury is damage to the spinal cord. It s an extremely serious type of physical trauma that s likely to have a lasting and significant impact on most aspects of daily life.

The spinal cord is responsible for sending messages from the brain to all parts of the body. It also sends messages from the body to the brain. We are able to perceive pain and move our limbs because of messages sent through the spinal cord.

If the spinal cord sustains an injury, some or all of...more
Last Updated: 8 years ago• Featured Tip
Share
Bookmark
Report
Profile Image

BASM, NDYSE, Mater of Yoga

Sexologist•Allahabad
banner-image
What causes orgasmic disorders?

Orgasms are intensely pleasurable feelings of release caused by sexual excitement and stimulation. Difficulty in achieving orgasm can lead to dissatisfaction and problems in relationships. Orgasmic disorder or dysfunction, sometimes known as anorgasmia, inhibits one's ability to orgasm during sexual intercourse or other sexual activities. Both men and women can suffer from anorgasmia though it is more prevalent in women.

The three types of orgasm...more
Asked for male, 50 years old from Mumbai
Share
Bookmark
Report
Profile Image

C.S.C, D.C.H, M.B.B.S

Cardiologist•Alappuzha
Sleep paralysis can sometimes be a symptom of another sleep disorder called narcolepsy, which causes severe daytime sleepiness and an inability to stay alert for more than a few hours. Although there's no cure for narcolepsy, the condition can usually be managed with appropriate medication.
Last Updated: 8 years ago• Featured Tip
Share
Bookmark
Report
Profile Image

FRHS, Ph.D Paed Neuro Rehabilitation, MP...read more

Physiotherapist•Chennai
banner-image
Physiotherapy and sleep paralysis have a deep connection when you have to treat sleep paralyses the intelligent way. To discover the benefits of physiotherapy in healing sleep paralysis, let's get a clear understanding of sleep paralyses first and then the role of physiotherapy.

What is sleep paralysis and its common causes?
Sleep paralysis is a sleeping disorder, its symptoms are such that you suddenly feel in the middle of the night or in mid sleep that you can't move, react, ta...more
Last Updated: 8 years ago• Featured Tip
Share
Bookmark
Report
Profile Image

Bachelor of Ayurveda, Medicine and Surge...read more

Ayurvedic Doctor•Pune
banner-image
The temporary inability to move one s own limbs or speak is known as paralysis. Paralysis is triggered by problems with the body s nervous system and affects the functioning of muscles all over the body. This condition can affect a single limb, the right or left side of the body, or the complete body. A paralytic attack is often caused by a stroke or damage in the nervous system. It can also be caused by exposure to radiation or toxins, autoimmune diseases, tumours and spinal cord trauma. Recove...more
Last Updated: 8 years ago• Featured Tip
Share
Bookmark
Report
Profile Image

Bachelor of Ayurveda, Medicine and Surge...read more

Ayurvedic Doctor•Noida
banner-image
It is necessary that you detoxify your body after regular intervals because with detoxification, you not just remove the dangerous toxins from your body but also increase the vitality of your body.

In Ayurveda, all natural ingredients are used for detoxification. Ayurveda works wonders in cleansing the blood by removing impurities and toxins, accumulated in various organs of the body such as the liver, intestines, kidneys, lymphatic system, lungs and skin. It is equally effective in cas...more
book_appt_icon
Book appointment with top doctors for Hyperkalemic Periodic Paralysis treatment
View fees, clinic timings and reviews
chat_icon

Ask a free question

Get FREE multiple opinions from Doctors

posted anonymously
Pristyn Care Banner