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Schnitzler Syndrome - Things You Must Know About It!

Dr. Manju Keshari 88% (46 ratings)
MBBS, MD - Dermatology , Venereology & Leprosy
Dermatologist, Ghaziabad
Schnitzler Syndrome - Things You Must Know About It!

Schnitzler’s syndrome is a very rare condition described by a reddish rash that looks like hives (urticaria) and lifted levels of a particular protein in the blood (monoclonal IgM gammopathy). Symptoms connected with the Schnitzler disorder may include increased levels of fever, joint inflammation, joint pain (arthralgia), bone agony, and different discoveries, for example, swollen lymph nodes (lymphadenopathy). It also causes weight reduction, discomfort, exhaustion, and broadened spleen and liver. This condition should be treated in terms of taking care of the symptoms so that they do not become debilitating.

Some of the other symptoms include the following:

  • Urticaria (hives) depicts red raised patches of the skin. These are once in a while irritated. They may last for about 12 hours to 3 days. This may become severely painful if not treated in time.
  • 80% of such patients suffer from painful or swollen. A few patients experience bone pain as well.
  • High fever might be there accompanied by chills and night sweating. This can give rise to further uneasiness and is usually caused when the immune system is attacked by the ailment.
  • One of the main symptoms of the Schnitzler disorder is monoclonal gammopathy. This mostly means a raised level of immunoglobulin M (IgM)

Reasons behind it

The main cause behind the Schnitzler syndrome is unknown. Specialists believe that particular parts of the immune system may not work appropriately in the end because of the Schnitzler syndrome. Individuals with the Schnitzler disorder additionally have monoclonal IgM gammopathy, in which abnormal production of immunoglobins result in elevated levels of immunoglobulin M (IgM) in the body. Immunoglobulins are proteins delivered by the white blood cells. A few analysts believe that IgM antibodies accumulate in the skin (epidermis), setting off a reaction that causes the rash. At the time of diagnosis, IgM levels may just be somewhat raised and may stay stable for quite a long time.

Diagnosis

The diagnosis of the Schnitzler disorder is based upon an intensive clinical assessment, patient history, rejection of different other disorders and proof of fever, joint pain or aggravation, bone pain, discernible lymph nodes, amplification of the liver or spleen, lifted quantities of white platelets (leukocytosis), raised red platelet (erythrocyte) or anomalies, which can uncover expanded bone thickness (osteosclerosis).

Treatment:
Anakinra is a successful treatment for Schnitzler syndrome. It is also very commonly used to treat rheumatoid joint inflammation. The following medicines and therapies have been proven to be successful for treating the Schnitzler disorder over a period of time. These are as follows:

  1. Antihistamines
  2. Nonsteroidal calming specialists
  3. Systemic steroids (prednisone)
  4. Hydroxychloroquine
  5. Colchicine
  6. Dapsone
  7. Pamidronate
  8. Thalidomide
  9. Pefloxacin
  10. Phototherapy
  11. Immunosuppressive specialists (ciclosporin, methotrexate, cycloposphamide)
  12. Biologic specialists (tocilizumab, rituximab)

The Schnitzler disorder is a long-term infection, so stopping a promising treatment can tend to cause a relapse and may cause the disease to reappear. Also, the medicines mentioned above should not be taken without consulting a doctor as they can have sever side effects, if not administered under the guidance of a physician.

Peptic Ulcers - Treating It With Homeopathy!

Dr. Shailesh Sancheti 89% (62 ratings)
MD - Homeopathy, BHMS
Homeopath, Pune
Peptic Ulcers - Treating It With Homeopathy!

One of the most common problems with the gastrointestinal system, peptic ulcers occur when the lining of the stomach - the esophagus or the small intestines, gets damaged. The damage occurs due to the development of sores on the lining which may be due to inflammation caused by certain bacteria, or due to erosion caused by the stomach acids. This can be a very painful disorder and end up severely limiting your life. Peptic ulcers can cause intense abdominal pain, vomiting nausea, indigestion and sudden unexplained weight loss.

The Homeopathic Approach to Curing Peptic Ulcers

The treatment of peptic ulcers in conventional medicine primarily revolves around the treatment of symptoms. The symptoms may be suppressed for some time but eventually come back sooner or later. This results in a vicious cycle where the treatment becomes less and less effective over time. Homeopathy, on the other hand, has an approach of trying to correct the problems from the root and over time, remove the very cause that results in the problem. Some of the things a homeopathic doctor may ask you would include –

  1. Family history of ulcers
  2. General health history of the family to determine hereditary health problems
  3. Physical characteristics
  4. Psychological tendencies and likes and dislikes among other information

Homeopathy takes into account not just the symptoms but the general constitution of the patient as well. This helps not only cure the ulcers but also the pre disposition to developing it again.

Effective Homeopathic Medications

Some of the most effective homeopathic medications used in the treatment of peptic ulcers are mentioned below. However, you shouldn’t try to self-medicate as it is best to consult with a doctor who can properly diagnose the problems and prescribe medication which are specifically tailored for you.

  1. Argentum Nitricum – One of the most effective medication in treating ulcers, Argentum Nitricum is usually prescribed when you experience sharp burning pains from peptic ulcers that radiate to different area of the abdomen. The pain is akin to the feeling of gnawing inside the stomach. Other symptoms such as vomiting, belching and nausea may also be present.
  2. Nux Vomica – If you have peptic ulcers and even eating the slightest amount of food causes pain, then Nux vomica may be a good option and thus be prescribed by your doctor. Another indication in such cases is where the abdominal region is very sensitive and you may feel pain even with the slightest touch. Nux Vomica is also very effective if your peptic ulcer symptoms tend to get worse after the consumption of tea, coffee, spicy foods or alcoholic beverages.
  3. Kali Bichromicum – Sometimes, peptic ulcers may cause the food in your stomach to sit like a heavy load immediately after meals. This can make you very uncomfortable and unable to do any other form of work. This is often times accompanied by a low appetite. In such cases, Kali Bichromicum has been seen to work wonders.
  4. Lycopodium Clavatum – If you have burning pain in your stomach along with the bloating of your abdomen, then Lycopodium Clavatum is the best medication for you. Other indications for this medication are when ingestion of warm water helps relieve pain. If consuming certain vegetables such as cabbage and beans worsens the situation, then Lycopodium Clavatum could be the best medication in such a case.
  5. Carbo-veg – An all-rounder in the field of homeopathy, Carbo-Veg is also effective when treating peptic ulcers which are accompanied by heartburn and acidity as well as sour belching. The pain from the ulcers may extend from the stomach all the way to the back. Other indication wherein Carbo-Veg may be effective is where the stomach area becomes very sensitive to touch and even small amounts of food may suddenly cause the symptoms to deteriorate.
  6. Hydrastis Canadensis – Stomach or abdominal pain accompanied by weight loss is one of the major indications where this medication may be prescribed. The patient may become emaciated and have sharp cutting pains in the stomach. In such cases, Hydrastis has been seen to be very effective.
  7. Graphites – This medication is extremely useful where along with the ulcer pain, you may end up vomiting your food immediately after a meal. A sensation which is painful and constrictive may be present in your stomach. Along with these symptoms, Graphites are also very effective when you suffer from excessive belching.
  8. Phosphorus – If you exhibit typical symptoms of peptic ulcer such as sour belching and a burning sensation in the stomach after eating, Phosphorus could well be the panacea.

Quality of Life with Endometriosis!

Dr. Hardik Shah 91% (38 ratings)
MBBS, MS - Obstetrics & Gynaecology
Gynaecologist, Ahmedabad
Quality of Life with Endometriosis!

The tissue that lines the uterus is known as the endometrium. In some cases, it can grow outside the uterus. This is known as endometriosis. Endometriosis usually involves organs in the pelvic cavity such as the ovaries, fallopian tubes, bowel and lining of the pelvic cavity. In rare cases, it may involve the vagina, cervix and bladder as well.

Depending on the location and extent of endometrial tissue, it can be classified into four stages ranging from minimal to severe. Most cases of endometriosis fall into the minimal or mild category which involves mild scarring and superficial tissue implants. Moderate or severe endometriosis can cause cysts and severe scarring. Infertility is also commonly associated with severe endometriosis.

Pain in the pelvic area just before and during menstruation is one of the most characteristic symptoms of this disorder. This is because the overgrown endometrial tissue acts like normal endometrial tissue and is shed during menstruation. The only difference is that since there is no exit for this overgrown tissue, it is trapped in the pelvic cavity. The location of the implantation of endometrial tissue also plays a role in the amount of pain experienced. The deeper the implant, more the pain. Implants near areas with high nerve density are also more likely to be painful than implants in areas with low nerve density.  These implants may also release substances into the blood stream that can cause pain.

Other symptoms associated with this disorder are:

  • Painful intercourse
  • Painful urination
  • Pain during bowel movements
  • Infertility

These symptoms especially the pelvic pain can vary from month to month in terms of duration and intensity.

A few simple changes in your diet can help manage the symptoms associated with this disorder and in some cases, prevent it as well. Avoid processed food and foods that are high in sodium content. You should also avoid high-fat dairy and food that is rich in arachidonic acid. Instead, increase your consumption of carbs and green leafy vegetables. You could also add two tablespoons of walnut oil a day to your diet to help combat inflammation and the other effects of arachidonic acid.

Early stages of this disease can be treated with hormone therapy, but if it has progressed to the later stages, surgery may be needed. This surgery is performed laparoscopically and aims at removing all the implanted tissue from outside the uterus. However, in cases where the anatomy of the pelvic organs has been distorted by the implants, a hysterectomy may be required. This option, however, it usually considered only in cases where a woman does not have any plans of conceiving more children.

1 person found this helpful

Joint pain in ankle ,wrist and backache. Feel weak .pain behind the neck too. Have stopped having periods since 5 months .I have thyroid n take throxin 100 mg last 18 yars. What to do have huge belly and weight is 85 kg?

Dr. Julie Mercy J David Raja 89% (5203 ratings)
Erasmus Mundus Master in Adapted Physical Activity, MPT, BPTh/BPT
Physiotherapist, Chennai
Joint pain in ankle ,wrist and backache. Feel weak .pain behind the neck too. Have stopped having periods since 5 mon...
Our suggestion would be to do hot water fermentation along with Cold (ice) therapy. You shall also keep a pillow under the knee while sleeping, next is you can keep ice in the painful area for about 5--10 minutes.
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Hi, I am suffering from plantar foot pain since one month. But doctor ortho suggest me to continue brisk walking. If I do that one. I am getting too much pain, though am wearing running shoes with gall sole in that. After returning home (1 hr walking) can't able to walk and do my own work. please help in this matter any one. I want to loose my weight at any cost .my weight is 70 kgs.

Dt. Vibha Singh 90% (113 ratings)
BSc CND Hons, MSC DFSM
Dietitian/Nutritionist, Rudrapur
Hi, I am suffering from plantar foot pain since one month. But doctor ortho suggest me to continue brisk walking. If ...
Dear check your uric acid first ,second loose your weight but nt by medicine bcaz it raise your weight more nd increase kidney load. So try to follow healthy plan but till then put your leg in hot & cold water alternatively.
4 people found this helpful
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Hello doctor, Can any one please suggest what treatment is suggested on lower back pain, facing problem with forward bending with severe pain.

Dr. Julie Mercy J David Raja 89% (5203 ratings)
Erasmus Mundus Master in Adapted Physical Activity, MPT, BPTh/BPT
Physiotherapist, Chennai
Hello doctor,
Can any one please suggest what treatment is suggested on lower back pain, facing problem with forward ...
This is a general low back ache and for this you can follow these measures: one keep a pillow right under the knee while sleeping, next is you can keep ice in the painful area for about 5--10 minutes, if pain still persists you can stretch your body by twisting the waist on both sides how we used to do in the school drill similarly you can try which will help you relax as well will reduce the pain. It looks like you are anaemic. If you have back pain after you sit for long hours then it is due to your haemoglobin levels as it is important to check that. Anaemia always leads to the symptoms of being tired and also having back / leg pain though there may not be any pathological reasons for back pain. If you have leg pain then you have to rule out the casues for having leg pain. First of all check your weight and your haemoglobin levels, as Anaemia always leads to the symptoms of being tired and also having leg pain though there are no issues with the knee joint or back pain. If not if the pain radiates down the back of thigh and legs then it might be due to sciatica. Kindly consult the nearby physiotherapist. Hope you recover soon from the leg pain. •Standing hamstring stretch: Place the heel of your injured leg on a stool about 15 inches high. Keep your knee straight. Lean forward, bending at the hips until you feel a mild stretch in the back of your thigh. Make sure you do not roll your shoulders and bend at the waist when doing this or you will stretch your lower back instead of your leg. Hold the stretch for 15 to 30 seconds. Repeat 3 times. •Cat and camel: Get down on your hands and knees. Let your stomach sag, allowing your back to curve downward. Hold this position for 5 seconds. Then arch your back and hold for 5 seconds. Do 3 sets of 10. •Quadruped arm/leg raise: Get down on your hands and knees. Tighten your abdominal muscles to stiffen your spine. While keeping your abdominals tight, raise one arm and the opposite leg away from you. Hold this position for 5 seconds. Lower your arm and leg slowly and alternate sides. Do this 10 times on each side. •Pelvic tilt: Lie on your back with your knees bent and your feet flat on the floor. Tighten your abdominal muscles and push your lower back into the floor. Hold this position for 5 seconds, then relax. Do 3 sets of 10. •Partial curl: Lie on your back with your knees bent and your feet flat on the floor. Tighten your stomach muscles. Tuck your chin to your chest. With your hands stretched out in front of you, curl your upper body forward until your shoulders clear the floor. Hold this position for 3 seconds. Don't hold your breath. It helps to breathe out as you lift your shoulders up. Relax. Repeat 10 times. Build to 3 sets of 10. To challenge yourself, clasp your hands behind your head and keep your elbows out to the side. •Gluteal stretch: Lying on your back with both knees bent, rest the ankle of one leg over the knee of your other leg. Grasp the thigh of the bottom leg and pull that knee toward your chest. You will feel a stretch along the buttocks and possibly along the outside of your hip on the top leg. Hold this for 15 to 30 seconds. Repeat 3 times. •Extension exercise: Lie face down on the floor for 5 minutes. If this hurts too much, lie face down with a pillow under your stomach. This should relieve your leg or back pain. When you can lie on your stomach for 5 minutes without a pillow, then you can continue with the rest of this exercise.
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Hi I am suffering from hypothyroid since long approx 8 year age 34 .I was using 150 mcg tab in morning I tested t3 t4 tsh which was normal on 13 Feb after 13 Feb I started 125 mcg tab then check again on 24 Feb my t3 t4 is normal but tsh is high. I started regular exercise in gym from last 1.5 hence I decided to reduce mcg 150 to 125. What should I do now it need to start again 150 mcg.

Dr. Kalyani Badwaik 89% (1121 ratings)
BHMS, M.D.
Homeopath, Pune
Hi I am suffering from hypothyroid since long approx 8 year age 34 .I was using 150 mcg tab in morning I tested t3 t4...
Hello Lybrate user, take homeopathic treatment along with thyroxine/ eltroxin (synthetic hormone) for   hypothyroidism to ensure good results. It is safe, natural and holistic way of treatment. Natural homeopathy medicines like calcerea, natrum, etc.; are highly effective for hypothyroidism. Homeopathic medicine are selected individually on the basis of thorough details of patient like medical history, routine, causes, temperament etc.; such well selected remedy naturally improves the thyroid gland, balance thyroid hormones level naturally and ensure relief in symptoms of hypothyroidism. Message back for online homeopathic consultation.
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Joint pain in fingers of hands swelling also and unable to even hold any thing properly the pain is always what to do?

Dr. Julie Mercy J David Raja 89% (5203 ratings)
Erasmus Mundus Master in Adapted Physical Activity, MPT, BPTh/BPT
Physiotherapist, Chennai
Joint pain in fingers of hands swelling also and unable to even hold any thing properly the pain is always what to do?
This might be due to lack of blood circulation in the hands and we suggest to do contrast bath therapy ie. Immersing in cold/hot water in the interval of 3-5 minutes which will help you reduce the pain.
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Pregnancy - Things To Do & Avoid!

Dr. Shaivalini Kamarapu 90% (305 ratings)
MBBS, MS - Obstetrics and Gynaecology
Gynaecologist, Warangal
Laxatives will help you with constipation without causing harm. True or false. Take this quiz to know more.
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I am 56 years I have shoulder pain early morning how I can free from shoulder pain.

Dr. Julie Mercy J David Raja 89% (5203 ratings)
Erasmus Mundus Master in Adapted Physical Activity, MPT, BPTh/BPT
Physiotherapist, Chennai
I am 56 years I have shoulder pain early morning how I can free from shoulder pain.
It is called as peri arthritis shoulder and for that you can do hot water fermentation and ice therapy at home. If you have shoulder pain then the stiffness will develop more that might make the arm to have less improvement which might make you to feel more pain the arm. And also cervical pillow can be used which might make you to have better posture of the shoulder neck and arm.
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