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IVF - How Is It Different From Tubal Ligation Reversal?

IVF - How Is It Different From Tubal Ligation Reversal?

In vitro fertilization (IVF) includes empowering the woman with medicines, taking various eggs from her ovaries, fertilizing them with her partner’s sperm, and inserting a portion of the subsequent embryos into her uterus with the trust that one will form into a fetus. 

Tubal ligation reversal, on the other hand, requires a laparotomy, which needs a much bigger entry point on the abdomen, usually around four to six fingers long. Since the skin, each of the muscles, and different tissues of the stomach must be sliced through, there is extensively more uneasiness and longer recovery time required after the surgery, when compared with laparoscopic surgery, for example, with a tubal ligation. 

Here are a few common differences: 

  1. Sperm quality: The male partner needs a sperm test before basic procedures of either of the two. In case that the sperm quality is great, then the couple could consider proceeding. In case that the sperm quality is poor, in vitro treatment is the better alternative. With IVF, poor sperm quality is effectively overcome. 
  2. Tubal status: The length of the remaining tubal stumps after tubal ligation is an important aspect. The more extended the two remaining stumps are on each side, the better and more effective is the pregnancy. The shorter the stumps, the lower are the odds for pregnancy. 
  3. Status of other pelvic conditions: Pelvic endometriosis or any scar tissue in the range of the tubes or ovaries would diminish the chance for accomplishment after tubal ligation reversal. Although, IVF pregnancy achievement rates are usually not influenced by these conditions. Along these lines, in vitro fertilization is most likely a superior alternative in women with noteworthy endometriosis or pelvic scar tissue. 
  4. Female age: Chances for pregnancy with either tubal ligation or IVF decrease in the mid to late thirties and significantly reduce at the age of thirty-eight. By age forty-three or forty-four, not many women will have the capacity to have a baby using either approach. 
  5. Egg amount and quality: A few women have a decrease in either egg amount or quality prior in life than anticipated. In this manner, the woman’s ovarian capacity needs to be tested before a choice is made in regards to whether to continue with either tubal ligation or in-vitro fertilization. AMH levels, ovarian antral follicle number, and day 3 FSH levels are generally done to evaluate ovarian capacity or hold. 
  6. Doctor intervention: The greatest favourable position of tubal ligation reversal over IVF is that once the woman has experienced the surgery she ideally will not require any medication through the doctor, for example, medications or systems, keeping in mind the end goal to get pregnant.

Diabetes And Male Infertility - Know Are They Connected!

Diabetes And Male Infertility - Know Are They Connected!

About 40% of couples facing fertility issues are known to have male factor responsible for it. Amongst various causes, diabetes has emerged as one of the leading cause of male infertility. Longer the duration of diabetes, worse is the effect. It is known to affect sperm count as well as motility, leading to oligoasthenospermia. It also causes abnormal morphology of sperms, causing fertilization difficulties in couples undergoing assisted techniques. It is advisable to consult physician/ diabetologist and follow their advice. The strict control of blood sugars is recommended before planning pregnancy. It may also increase the risk of miscarriage if pregnancy happens. Exercise and diet help extensively in these cases as it does for any patient of diabetes.

Embryo Implantation - What Contribute Its Results?

Embryo Implantation - What Contribute Its Results?

The concept of egg quality of a woman is derived from the belief that the embryo implantation probability is powerfully related to the age and ovarian reserve of the woman. Thus, it is regarded that the quality of the egg is almost synonymous with the chances of embryo implantation. Its quality cannot be assessed merely by looking at the egg or measuring its ability to receive the fertilization by sperm or simply observing the initial embryo division.

There are a few important factors that contribute to the success or failure of the embryo implantation and some of them are:

  1. Diminished ovarian reserve: A woman with an increased FSH level on the third day of the menses is regarded as having diminished reserve of ovary. This implies that her ovary is not competent in sending feedback signals to the pituitary gland and the body responds by producing an increased amount of FSH for stimulating the ovary. For more than 10 years, it has been found that in over thousands of fertility treatment cycles, women with an increased FSH level have a lower egg quality.
  2. Advanced age of maternity: Even though the FSH level is normal, the age of the mother who provides the eggs plays an important role to determine the quality of the egg. Quite like women with increased FSH levels, eggs obtained from women aged more than 40 years can have some problems at a later stage of fertilization. Normal FSH levels are not considered a reassuring factor, owing to the lower implantation rate in females aged over 45 years.
  3. Diminished quality of egg: With an increase in age, the capacity of the mitochondria in producing energy slowly decreases. The egg is linked to the circulation before ovulation, and it is linked again after the embryo implantation. But during the one week time ranging from ovulation to implantation, the egg and the resulting embryo are contained in the zona pellucida and function on the basis of mitochondrial energy supply. The older age of the woman doesn’t cause any problem at the initial stage of ovulation. Its fertilization and embryonic development are also normal. But soon, it runs out of energy and stops dividing before reaching the stage of implantation.

Therefore, it is important to have the eggs tested to find out any sort of chromosomal abnormality. In case the mother is deficient of producing high-quality eggs, the best option is to have donor eggs.

Mitochondrial Concept:

Mitochondrial replacement (MRT, sometimes called mitochondrial donation) is a special form of in vitro fertilisation in which the future baby's mitochondrial DNA comes from a third party. This technique is used in cases when mothers carry genes for mitochondrial diseases. The two most common techniques in mitochondrial donation are pronuclear transfer and maternal spindle transfer.

Cells are the tiniest part of any organism including the human body, but has various parts within, which have specific functions. The mitochondria, for instance, are the batteries of the cells and produce energy for all functions, including cellular movement and adequate cellular function.

The egg, being a single cell, also is highly dependent on the mitochondria for its optimal function. For an egg to be healthy, it should have optimal energy, and that comes only when the mitochondria is functioning at its best. This determines the overall quality of the egg too. Poor eggs, it is well established, is one of the major cause of infertility, as it cannot implant itself and sustain the entire term of pregnancy.
Studies have confirmed that eggs have more mitochondria than normal cells, as their energy requirements are higher.

The ovaries have cells called precursor cells, which eventually can become eggs and get fertilized. Studies have shown that when mitochondria from these precursor cells are infused into the fertilized egg, the overall quality of the egg improves and therefore improves chances of fertilization.

Mitochondrial transfer is the new technique which is being developed and has resulted in a baby but involves third party IVF and hence is in a ethical debate.

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Fertility - How Ayurveda Can Enhance It?

Fertility - How Ayurveda Can Enhance It?

Infertility is a condition when a woman fails to conceive even after a year of unprotected regular sexual intercourse. If she is unable to carry the baby to term, it’s called infertility too. Mankind has made giant leaps in curing this condition. But something’s still lacking. This is where the ancient healing system of medicine Ayurveda comes in.

There are a number of reasons for infertility we know women can’t get pregnant if their partner’s sperm count is low or if they have obstructions in their reproductive system like blocked fallopian tubes or fibroids etc. But Ayurveda goes beyond all these. According to it, infertility arises when “shukra dhatu” which produces eggs in women and sperms in me, is weak due to lack of proper nutrition which may happen as a result of poor digestion, lack of balanced diet or due to a presence of ‘ama’ or toxins in the body.

Ayurveda also prescribes that sexual indulgence and promiscuity can cause infertility due to the decrease in shukra dhatu. Ayurvedic fertility enhancers

For men:

  1. Kapikacchu: A potent antioxidant, this medicine reduces oxidative damage to sperm. It is also an aphrodisiac and helps increase sperm count.
  2. Gokshura: Contains a precursor to testosterone, and thus improves sexual desire and sperm production.

For women

  1. Ashoka: It stimulates the endometrium in uterus and ovaries and aids ovulation.
  2. Lodhra: Cure's female disorders which stop conception and increase levels of reproductive hormones like FSH and LH essential for conception.
  3. Shatavari: Nourishes ovum and increases fertility because it contains estrogen-like compounds.
  4. Gokshura: This herb is helpful for both men and women. It helps cure erectile dysfunction and is very effective in improving sperm count and motility. Whereas in women it works as a fertility tonic that stimulates the ovaries and thus cures PCOS, a leading cause of infertility in women.

What Ayurveda recommends is eating a diet rich in foods like ‘ghee’, milk, almonds, walnuts, sesame and pumpkin seeds to improve health and thus shukra that. Since ‘vata’ dosha is closely connected to the reproductive system in women, it should be regulated for proper ovulation. And so should be extra stress and worry in both men and women.

Other ways to cure infertility, especially in men, is to wear loose underwear so that ‘pitta’ is controlled and the sperm production is good. This also ensures good quality of sperm. Ayurveda should never be practised by self. Always consult an expert who will prescribe the right medicines for infertility. Doing everything in balance is crucial too. So be mindful of what you eat, think, watch, read and eat right and develop a healthy body for getting rid of infertility.

Preserving Fertility While Battling Cancer!

Preserving Fertility While Battling Cancer!

Fertility Preservation: Options for Cancer patients

Survival rates among young cancer patients have steadily increased over the past two decades in part because of the development of more effective cancer treatments. Today, both women and men can look forward to life after cancer, yet many may face fertility issues as a result of the disease itself or these lifesaving treatments(chemotherapy or radiotherapy).

Fertility options for Men

Established fertility preservation options for men include A) sperm freezing (cryopreservation), in which a semen sample is collected, frozen, and stored for future use or B) testicular sperm extraction, during which sperms are aspirated from the testes through a short surgical procedure and frozen or C) testicular tissue freezing where tissue is checked for sperms and frozen for later use.

Fertility options for Women

Options for women to have children after cancer has evolved significantly in recent years. Women should be counselled for established techniques such as-

A) embryo freezing in which hormonal stimulation causes production of multiple eggs, which are removed & fertilized by sperm, embryos are then frozen for future use or

B) oocyte freezing where oocytes are directly frozen for future use or

C) ovarian tissue freezing, which is not established procedure, It is recommended for prepubertal girls.

Fertility options for Couples

Embryo cryopreservation is an established technique that has been proven to be the most effective one. This process is basically for couples who wish to delay pregnancy e.g.if anyone of them undergoing chemotherapy/radiation treatment or for social reasons in some cases.

Embryo freezing has shown the best results so far amongst all above techniques. They can be frozen for years. Before going ahead with fertility preservation in cancer cases, multiple things need to be taken into consideration which involves teamwork by oncologists, hematologists, fertility specialists, oncosurgeon. It definitely gives a solution for those who wish to preserve their dream to parenthood !!!

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Stress & Fertility - Is There A Link?

Stress & Fertility - Is There A Link?

Nowadays, the entire world along with the inhabitants have become so fast-paced that the most common matter which affects almost everyone is stress. Getting stressed is not only unhealthy for your body and has an impact on every aspect of life including fertility. You might be wondering that how stress can affect your fertility as they sound unrelated. Read on to understand. Till date, though no direct correlation between stress and infertility has been established, it has been observed that if a couple who is trying their best to conceive is under stress, there appears to be a problem. Now, have a look at a few of the impacts that stress has on fertility.

How stress affects fertility?
Too much stress has an impact on the proper functioning of the hypothalamus. It is that part of the brain which has the responsibility of sending as well as receiving all type of signals from the reproductive system. The menstrual cycle is one of the most complex communicating systems between the brain and ovaries, and thus stress may affect the fertility cycle. In this manner, stress may delay the ovulation, and in severe cases, it may also prevent the women from ovulating.

Another point that needs to be mentioned is that due to stress fewer mature eggs may be available. Some of the studies focus on the point that the women, who were stressful as well as anxious regarding their IVF (In-Vitro Fertilization), possessed approximately twenty percent fewer eggs than they usually could produce that are viable for fertilization.

Dealing with stress
Different women have their way of dealing with stress. Thus, the impact this unwanted issue has on a woman might not be similar to the reactions of another woman. Many people start to gain weight in such stressful periods while some lose a lot of fat. A fact is sure that stress is not at all healthy and good for an aspiring mother.

So, now that you are aware of stress and infertility and how stress affects your fertility, the best possible course is to eliminate stress from your life as much as possible in a systematic manner. To reduce stress, you must have an adequate amount of sleep and also practice exercise on a regular basis. You may also opt for other habits like practising yoga, meditation, prayer, seek counselling, etc.

Thus, the bottom-line is, if you are trying to get pregnant, either naturally or through IVF due to genetic or medical reasons, relieving yourself from stress is crucial. If you are willing to know more about stress and infertility and how stress affects your fertility, then you may consult with your physician who would guide to adopt necessary measures.

Fertility - Can Homeopathy Enhance It?

Fertility - Can Homeopathy Enhance It?

Approximately 15-20% of couples worldwide have difficulties conceiving, and this can be due to many causes, including hormonal imbalances in one or both partners. Infertility has become a more serious problem in the past century, and its causes are mostly related to our way of life. Smoking, drinking and an unhealthy diet, together with high levels of stress, will definitely affect your ability to conceive, creating imbalance in your body. Homeopathic medicine is widely used as an alternative to conventional medicine, helping the body to treat itself and infertility homeopathic treatments are available for both men and women; there are many homeopathic medical journals that will attest to their efficiency.

Homeopathic medications for fruitlessness include an all-characteristic methodology. Discover the best vitamins, herbs and supplement mixes accessible to help you get pregnant actually.

Barrenness homeopathic medications are turning out to be more prevalent among couples who experience fruitlessness issues, since they are all-normal, work generally quick and are moderate in contrast with customary drug.

The most vital components of fruitlessness homeopathic medicines, which will work ponders much of the time of barrenness are the accompanying:

Ripeness Diet-

In spite of the fact that it may sound somewhat ungainly, it is really a solid eating routine arrangement, which is useful for ripeness, as well as numerous different advantages for your body. Most importantly, you ought to surrender smoking and drinking liquor, and attempt to lessen your caffeine admission. Eat whatever number natural products of the soil as could reasonably be expected; it is vital to just eat natural food, to stay away from herbicides or pesticides which cause harm to the body.

Homeopathic meds for infertility in females because of corrosive vaginal releases:

There are top-grade homeopathic drugs for infertility in females because of corrosive vaginal releases. These homeopathic pharmaceuticals for infertility in females are utilized where the vaginal releases are harsh, dangerous and slaughter the sperms. It is a homeopathic prescription for infertility in females when the vaginal release resembles the white of an egg, bitter, abundant and warm. In such cases, it supports simple origination. Next homeopathic pharmaceutical is shown for infertility in ladies who have harsh, bothering, rich, nectar shaded vaginal releases. The release likewise notices harsh.

Homeopathic medications for infertility in females due to excessively abundant or excessively drawn out periods:

Two superb homeopathic prescriptions for infertility in females from bountiful or delayed periods are there. One is fundamentally utilized when a female with infertility has excessively abundant and too dependable periods. The periods likewise show up before time. To endorse the other, the fundamental symptoms are early and abundant menses with infertility. Leucorrhea, paleness, shortcoming, tiredness and exhaustion may likewise endure with menorrhagia. Among these homeopathic solutions for infertility in females, one medicine is additionally recommended where a propensity for incessant premature births is available.

All the medicines have to be taken under the guidance of the experts.

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IVF - Misconceptions Which You Should Stop Believing!

IVF - Misconceptions Which You Should Stop Believing!

IVF or In-vitro fertilization is a procedure in which a woman’s egg is taken out of her body and infused with the sperm in a medical laboratory. This is an artificial method of fertilization, which can help people overcome a range of issues stopping them from becoming biological parents to their child. However, as is the case with many modern medical procedures, there exist several misconceptions about IVF and what it does.
Here is a look at some of the myths concerning IVF, which you definitely should not believe.

  1. IVF is the only option for infertility: This is a misconception among the populace. If you or your partner is diagnosed with a fertility issue, your doctor will suggest many other treatment options prior to suggesting IVF. In-vitro fertilization is used when all other treatment options have failed to produce the desired result or pregnancy. For instance, infertility in women can be caused due to the formation of cysts in the uterus. A simple surgery to remove such cysts may be enough to cure infertility, therefore not needing IVF for pregnancy.
  2. Insurance covers IVF treatment: Most health insurance does cover the cost of treatment for infertility. However, the IVF procedure is rarely covered by any such insurance. This is because the treatment involves a considerable cost that most insurance companies do not want to deal with. So, before signing on to health insurance, ensure that you and your partner are aware of the treatments covered by the same policy.
  3. IVF raises the chances of having twins or triplets: There is some truth to this myth. During the initial In-vitro fertilization cases, doctors often fertilized two eggs at once and fused them into the mother. This was done because the success rate for such a procedure was lower and doctors hoped that fertilizing two eggs at once would increase the chances of pregnancy. However, modern medicine has advanced quite a bit since then. This has led to clinics implanting only one fertilized egg in the mother, leading to the birth of just one child.
  4. IVF babies are at greater risk for birth defectsAnother misconception that may harbour is that babies born through IVF are rarely healthy. However, this is not true. Birth defects in IVF babies occur at the same frequency as they do for babies born through the natural process. So, people should stop worrying about their children suffering from chronic diseases, just because their mothers have undergone the IVF procedure.
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How Can Husbands Contribute During An IVF?

How Can Husbands Contribute During An IVF?

Having a baby is a life-changing event. For every couple the process is different. For some getting pregnant happens naturally but for others, the whole process of getting pregnant can become an ordeal. For couples experiencing difficulty in getting pregnant, there is IVF (in vitro fertilization) fertility. It should be stressed that IVF is one of the many ways in which a couple can have a child.

The women are generally the one undergoing the treatment. The husband’s male ego maybe hit owing to the fact that he is unable to produce a baby through the natural process. The problem of infertility may be traced back to the husband or the wife or both. In an IVF treatment, the woman is generally injected with hormonal medications and the egg is extracted and then fertilized with a sperm and the resulting embryo is implanted in the womb. The whole process might be overwhelming for the woman. The husband basically plays a passive role but is pivotal in providing support and love to his better half.

What can husbands do during an IVF treatment?

  1. Appreciation- The decision of having a baby is an important one. However, getting pregnant through IVF can take a toll on the woman with mood swings and low self-esteem. In such situations, the husband needs to play the supporting role and appreciate and praise her for doing such an incredible task. If she is feeling down, cheer her up and do not criticize. Pamper and appreciate her.
  2. Providing Emotional and Physical support- Women are generally emotional by nature and the process of IVF can make them more emotional. A woman can experience fatigue and nausea during the process. The husband should be around to help his wife in doing household chores and any other activities she needs help in doing. Remember a simple hug or just holding hands can create a positive feeling in your partner. You should spend time together
  3. Research- The women bears the maximum burden, being the one to go through the IVF treatment, experiencing pain and giving birth and taking care of the baby post-delivery. A husband can relieve some stress by undertaking thorough research on IVF fertility. It’s very important to discuss the consequences as well, like what measures can be adopted if the treatment is unsuccessful.

The whole process IVF might seem difficult and expensive but with the support of the right doctors and your partner, you will soon get to experience parenthood and overwhelming love for your baby.

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Ovarian Cancer - Who Are At Risks?

Ovarian Cancer - Who Are At Risks?

The cancer of the ovaries is known as ovarian cancer. In women, there are two ovaries present on each side of the uterus. These ovaries are as big as an almond in size and produce egg also known as ova. They also secrete the hormones progesterone and estrogen.

Ovarian cancer goes undetected until it spreads to the abdomen and pelvis. When detected at this stage then it might be fatal and the treatment gets difficult. An early-stage ovarian cancer where the cancer is restricted in the ovaries is much easier to treat with high success rates.

Risk Factors of Ovarian Cancer

1. Age - With increasing age the risk of ovarian cancer is higher and is more common in women who are 60 and above. It is less common in women below 40 years of age and develops often after menopause.

2. Obesity -Women who have a body mass index of 30 are at risk of developing ovarian cancer.

3. History of Reproduction - It is believed that women who conceive before 26 and carry the full term have a lower risk of ovarian cancer. However, the risk is higher in those women who get pregnant after 35 or who do not have a full term pregnancy. Also, breastfeeding the baby lowers the risk.

4. Gene Mutation - Inherited gene mutation causes some percentage of ovarian cancer. These genes are called breast cancer genes 1 and 2 (BRCA1 and BRCA2). These were initially found in cases with breast cancer but also pose a great risk for ovarian cancer. Also, gene mutation leading to Lynch syndrome plays an important role in increasing the risk of ovarian cancer.

5. Family History - If a woman's mother, sister or daughter is suffering from ovarian cancer then she is at a higher risk of developing the same. The risk also increases if someone from the father's side also has ovarian cancer.

6. Fertility Drugs - Drugs like clomiphene citrate, if used for more than a year can increase the risk of cancer. The risk is even higher if a woman taking the drug does not get pregnant.

7. Hormone Therapy and Estrogen Therapy - Long term use and large doses of estrogen can cause an increased risk. However, if estrogen is used in combination with progesterone then the risk is less.

8. Age of menstruation and menopause - If menstruation starts before 12 and menopause occurs before 52 then there is a higher risk of getting cancer.

9. Diet - A low-fat vegetarian diet has less risk of the disease. Fresh fruit and vegetables should be included in diet along with pulses, rice, pasta, beans, cereals and bread.

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