There are more than hundred varieties of blood cancer, but the most common ones are leukemia, lymphoma, and myeloma. Acute myeloid leukemia (AML), a type of leukemia, is when the white blood cells in the marrow begin to grow uncontrollably. This is an acute condition and both the onset and progress are very rapid. The cause is not known, and given the rapid progress, even treatment is often difficult. A more severe form of AML is the APML which is acute promyelocytic leukemia, which leads to reduced number of white and red blood cells and plasma.
This causes the following symptoms:
What is different about APML?
There is one distinguishing factor with APML, which is that they contain a protein which when released into the bloodstream can cause severe bleeding, which may be very difficult to control. Chemotherapy kills these cells and so releases the proteins into the bloodstream. These cells need to be managed without chemotherapy, as the patient can even die of uncontrolled bleeding. With medical advances, two non-chemotherapy agents have been identified – all-trans retinoic acid (ATRA, vesanoid, or tretinoin) and arsenic trioxide (ATO or trisenox).
With both these drugs, there is a significant side effect, known as differentiation syndrome. Often seen during the first cycle of treatment, this happens when the leukemia cells release a protein into the blood. Symptoms include fever, breathing, kidney damage, and severe fluid buildup. With these two drugs being widely used effectively, chemotherapy is not the only treatment option for APML. In case you have a concern or query you can always consult an expert & get answers to your questions!
Chemotherapy can be frightening, and the very thought of going through it can be an ordeal for most people. Many resources and tips can be used to minimize the discomfort and lessen the burden. Let us have a look at a few of these.
Chemotherapy treatment can be emotionally daunting. Having a few precautions like the ones stated above can make all the difference in how successful we are in coping with it.
What is anemia during pregnancy?
Anemia is a condition that can affect anyone and is defined as a deficiency in iron, an essential mineral in our body. Anemia during pregnancy is a common affliction of pregnant women, due to many physical and hormonal changes that occur during pregnancy.
Any deficiency in nutrients can be fatal and leaves your body without the key resources it needs, but this can be a dangerous concern during pregnancy. Iron is an essential mineral in the production of red blood cells and hemoglobin, which is necessary to carry oxygen and other nutrients to different areas of the body. Expecting mothers contribute a large amount of their nutrient intake to their growing fetus ;which makes it even more important for them to ensure that their nutrient levels are adequate.
Unlike traditional anemia, which can affect anyone during pregnancy, it is risky, especially during the first and the third trimester.
During third trimester
In the third trimester, the final three months of a pregnancy term, there is a particular risk of anemia. Even if you aren’t anemic at the start of your pregnancy, the chances of being anemic get high by the end of your term. Approximately 15-20% of women experience anemia during pregnancy. Having anemia during the third trimester can increase the risk of a pre-term baby or a low birth weight of the baby.
Contrary to popular belief, anemia is not exclusively caused by a deficiency in iron. While a lack of iron causes 80-95% of anemia cases, deficiencies in other essential compounds can also result in anemic symptoms.
1. Iron-deficiency anemia
This is the most common form of anemia caused by a lack of iron in the body. It limits your body’s ability to produce hemoglobin and deliver oxygen to the necessary organ systems and tissues.
2. Folate-deficiency anemia
Folic acid is a part of the b family of vitamins and is closely linked to metabolic processes and the risk of neural tube defects in a fetus. While rarer than iron-deficiency anemia, it still requires specialized treatment to bring folate concentration back to a healthy level.
3. Vitamin b12 deficiency anemia
Pernicious anemia is a rare form of anemia in which your body attacks the cells in the stomach that are required to absorb vitamin b12. Without this essential vitamin, similar to a lack of iron, your body is unable to produce red blood cells.
Exhaustion is one of the first and most notable symptoms of anemia, making you feel physically sluggish and cognitively slow.
2. Muscle weakness:
Without proper oxygenation, muscles are unable to function properly, leading to muscle aches, soreness, and general weakness.
Preeclampsia, high blood pressure duringpregnancy, can be a very serious symptom of anemia during pregnancy, and will often require additional treatment to keep under control.
The physical exhaustion caused by anemia and the lack of oxygen to organ systems can make normal respiration a struggle. This can also cause dizziness in some pregnancies.
5. Irregular heartbeat:
Tachycardia is a potentially life-threatening symptom of anemia during pregnancy, in which your heart “skips” beats. This can lead to more complicated cardiovascular issues during pregnancy.
If you suspect that you are experiencing anemia during pregnancy, a visit to the doctor is highly recommended. They can perform a simple blood test to determine your levels of hemoglobin. This is the most reliable and rapid means of determining whether you are experiencing anemia during pregnancy.
Given, how common it is for women to experience anemia during pregnancy, there are a number of formal treatments, as well as home remedies and natural therapies that can prevent or effectively treat this condition.
1. Iron supplements
This is the easiest and most common recommendation for addressing anemia during pregnancy. Though iron supplements may increase the concentration of iron in the body, the greater issue may be an inability to absorb iron, which can be mitigated by vitamin c intake.
2. Prenatal vitamins
Considered a preventative measure, more than a treatment option, prenatal vitamins can ensure that your iron levels remain adequate throughout pregnancy.
3. Iron-rich diet
Your dietary choices will have the largest impact on the amount of iron in your body. Within the boundaries of your pregnancy diet, add foods like spinach, red meat, legumes, high-starch foods and dried fruit.
4. Vitamin c intake
Ascorbic acid is critical to iron absorption in the gut. By ensuring that you have proper levels of vitamin c, you can effectively avoid anemia during pregnancy. Include foods like citrus fruits, leafy green vegetables and bell peppers in your diet for better results.
What do we mean by the term Anemia?
It is described as a decrease in the total number of red blood cells, or hemoglobin in the blood, or a decreased oxygen-carrying capacity of blood.
How to know if an individual has Anemia?
Anemia by Chronic Red Blood Cell Destruction/Hemolytic anemia
In case you have a concern or query you can always consult an expert & get answers to your questions!
Vitamin B12 Deficiency Anemia
What is vitamin B12 deficiency anemia?
Vitamin B12 deficiency anemia is a condition in which your body does not have enough healthy red blood cells, due to a lack (deficiency) of vitamin B12. This vitamin is needed to make red blood cells, which carry oxygen to all parts of your body. Without enough red blood cells, your tissues and organs don’t get enough oxygen. Without enough oxygen, your body can’t work as well.
Folic acid, also called folate, is another B vitamin. Anemias caused by a lack of vitamin B12 or a lack of folate are 2 types of megaloblastic anemia. With these types of anemia, the red blood cells don’t develop normally. They are very large. And they are shaped like an oval, not round like healthy red blood cells. This causes the bone marrow to make fewer red blood cells. In some cases the red blood cells die sooner than normal.
What causes vitamin B12 deficiency anemia?
Vitamin B12 deficiency anemia is more common in people whose families come from northern Europe. It is caused by one of the following:
The inability to make intrinsic factor may be caused by several things, such as:
Other types of megaloblastic anemia may be linked with type 1 diabetes, thyroid disease, and a family history of the disease.
The inability to make intrinsic factor may be the result of several factors, such as chronic gastritis, gastrectomy (removal of all or part of the stomach), or an autoimmune condition (the body attacks its own tissues). Other types of megaloblastic anemia may be associated with type 1 diabetes, thyroid disease, and a family history of the disease.
Who is at risk for vitamin B12 deficiency anemia?
Risk factors for vitamin B12 deficiency anemia include:
What are the symptoms of vitamin B12 deficiency anemia?
Each person’s symptoms may vary. Symptoms may include:
The symptoms of megaloblastic anemia may look like other blood conditions or health problems. Always see your healthcare provider for a diagnosis.
How is vitamin B12 deficiency anemia diagnosed?
This type of anemia is usually found during a medical exam through a routine blood test. Your healthcare provider will take your medical history and give you a physical exam.
Your provider may give you additional blood tests. You may also have other evaluation procedures, such as a bone marrow biopsy.
How is vitamin B12 deficiency anemia treated?
Your healthcare provider will figure out the best treatment for you based on:
Vitamin B12 deficiency anemia and folate deficiency anemia often occur together and can be hard to tell apart. Treatment may include vitamin B12 shots (injections) and folic acid pills.
Foods that are rich in folic acid include the following:
Foods that are rich in both folic acid and vitamin B12 include the following:
Taking folic acid by mouth is more effective than eating foods rich in folic acid. Vitamin B12 is not as well absorbed by mouth as per injection.
Living with vitamin B12 deficiency anemia
Depending on the cause of your vitamin B12 deficiency, you may need to take vitamin B12supplements for the rest of your life. These may be pills or shots. This may seem difficult. But it will let you live a normal life without symptoms.
If your deficiency is due to a restrictive diet, you may want to work with a nutritionist. He or she can help ensure that you get enough vitamin B12 and other vitamins. Tell your healthcare provider about any symptoms and follow your treatment plan.
Key points about vitamin B12 deficiency anemia
With this condition, your body does not have enough healthy red blood cells, due to a lack (deficiency) of vitamin B
Symptoms Of Anemia!