Dr Jaydeep Shinde Diabetology Clinic

Diabetes is one of the most common problems that are caused by obesity, unhealthy and inactive lifestyle. It is a metabolic disorder in which the body is unable to store and use energy from food. Being physically inactive and eating unhealthy food are primary causes of diabetes. It is a long term condition, which causes high or unstable blood sugar levels in the body.

When a patient suffers from low blood sugar it is called Hypoglycemia and if the blood sugar levels are too high, it is called Hyperglycemia. Both are extremely harmful for a patient.

Type 1 and Type 2 and Gestational Diabetes:

Type 1

In Type 1 diabetes, the body does not produce insulin. The condition has no known cure and is usually hereditary in nature. Approximately 10% of those suffering from diabetes have Type 1 diabetes. Patients with Type 1 diabetes have to take regular medication, including insulin injections as well as take care of their diet.

Type 2

Type 2 diabetes happens when the body does not produce enough insulin for its proper functioning. 90% of all diabetic people suffer from Type 2 diabetes. It is usually caused by poor lifestyle choices, like physical inactivity and unhealthy food habits. The disease lasts a lifetime and is usually progressive in nature, but can be managed by taking regular medication, choosing an active lifestyle and maintaining proper body weight.

Gestational Diabetes

Diabetes during pregnancy is known as gestational diabetes. This has to be managed by taking medication or in extreme cases insulin shots. If undetected or untreated, gestational diabetes increases complications during childbirth, and causes unusual weight gain in the baby. However, gestational diabetes usually ends after the baby is born and women can go back to their normal lifestyle and eating habits post delivery.

Symptoms of Diabetes

1. Frequent urination
2. Extreme hunger or thirst
3. Weight loss
4. Problems with vision
5. Tingling or numbness of the extremities.
6. Unexplained fatigue
7. Dry skin
8. Cuts or sores that heal slowly
9. High number of infections

Who is at greatest risk for developing diabetes?

People who:

1. are 45 or over
2. are overweight
3. are habitually physically inactive
4. have previously been identified as having IFG (impaired fasting glucose) or IGT (impaired glucose tolerance)
5. have a family history of diabetes
6. are members of certain ethnic groups (including Asian American, African American, Hispanic American, and Native American)
7. have had gestational diabetes or have given birth to a child weighing more than 9 pounds
8. have elevated blood pressure
9. have an HDL cholesterol level (the good cholesterol) below 35 mg/dl and/or a triglyceride level above 250 mg/dl
10. have polycystic ovary syndrome
11. have a history of vascular disease

What is pre-diabetes?

Pre-diabetes is a condition of elevated blood glucose level that has not yet reached a diabetic level. Along with insulin resistance, pre-diabetes causes no symptoms. An individual may be pre-diabetic for years without knowing it. Pre-diabetes increases your risk of developing Type 2 diabetes and heart disease. Weight loss and exercise may halt the onset of diabetes from pre-diabetes by returning blood glucose levels to a normal range.

Intracytoplasmic Sperm Injection i.e. ICSI is different from conventional IVF i.e. In Vitro Fertilization because a single sperm is selected by the embryologist to be injected by a needle into the egg rather than a dish with many sperms placed near the egg so that the fastest swimming sperm enters it. Once the sperm is injected directly into the egg, it fertilizes, after which the embryo is transferred into the womb or uterus. 

Your doctor might recommend ICSI treatment for you if you have an extremely low sperm count resulting in infertility or other medical sperm conditions such as poor motility or poor morphology. It may also be suggested if prior attempts at IVF procedures have failed in fertilizing the egg or the fertilization rate is extremely low. You must also consider ICSI treatment if you resort to embryo testing or if the sperm needs to be collected from the epididymis or testicles surgically. 

However, you must keep in mind that if your partner has a genetic problem resulting in low sperm count, it could be passed on to your child, if you decide to use your husband's sperm for this process.

Success Rates of ICSI:
The success rate of ICSI treatment depends on your age and your fertility problem. Your eggs are healthier when you are young and as you age, chances are that they will become less healthy.
1. 35 per cent if you are under 35 years of age
2. 29 per cent if you are between 35 to 37 years of age
3. 21 per cent if you are between 38 to 39 years of age
4. 14 per cent if you are between 40 to 42 years of age
5. 6 per cent if you are between 43 to 44 years of age
6. 5 per cent if you are above 44 years of age

Advantages of ICSI Treatment:
Intracytoplasmic Sperm Injection gives you a chance to conceive a child genetically when most other options are exhausted. Males may be unable to ejaculate on the day the eggs are collected due to anxiety. ICSI proves to be advantageous because sperm may also be surgically extracted for this process. It is extremely helpful for those couples who suffer from unexplained infertility. However, one of the most important factors is that ICSI treatment does not affect your child's physical or mental health.