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Breast cancer begins when cells in the breast(s) start to grow out of control. It is understood as being the most common cancer, seen predominantly in females, globally. It is reasonably treatable and often curable.
1. Type: Adenocarcinomas constitute more than 95% of breast cancers with infiltrating ductal carcinoma (IDC) being the most common form of invasive breast cancer.
Frequently occurring breast cancers present as one of the following types mainly
1. Ductal Carcinoma In Situ (DCIS): Is the most common type of non-invasive breast cancer and is confined to the milk ducts of the breast. There is no invasion in the basement membrane. Pure DCIS metastasizes rarely. Non comedo cribrioform carcinoma is the most common DCIS found which, when compared to the comedo type, is mostly non-aggressive.
2. Infiltrating Ductal Carcinoma (IDC): Represents majority (about 3/4th) of the breast cancers, and is known to metastasize commonly to bones, lungs and liver.
3. Lobular Carcinoma In Situ (LCIS): Develops in multiple lobules of the breast (bilaterally). LCIS is less commonly seen, compared to DCIS.
4. Infiltrating Lobular Carcinoma (ILC): Represent about a tenth of all breast cancers and tends to metastasize to other regions of the body.
Less commonly occurring breast cancers such as
5. Inflammatory Breast Cancer: Is relatively uncommon and are caused probably owing to viral infections. The breast is warm, red and swollen.
6. Paget’s disease of the nipple: Is a rare form of breast cancer. It begins in the milk ducts and spreads to the nipple and areola.
7. Medullary Carcinoma
8. Mutinous Carcinoma
9. Tubular Carcinoma
10. Phylloides tumor etc all.
2. Gender: Affects the female populace predominantly. However, a small percentage of breast cancer is attributable to the male populace as well.
3. Etiology: No definite cause is known. However, diet, lifestyle, environment, hormonal/ reproductive factors, personal or family history of breast cancer especially in first degree relatives and also any benign breast disease history etc all are known to increase the risk of breast cancers. Specifically, excessive fatty diet, obesity, type 2 diabetes mellitus, benign breast disease, heredity/ inheritance of mutated breast cancer genes 1 (BRCA1) and 2 (BRCA2), smoking, alcohol intake, infertility, estrogen therapy/ hormone replacement therapy (long term) in post menopausal women, delayed age at first pregnancy, nulliparity (not having child), early menstruation, delayed onset of menopause, lactating mothers not breast feeding, exposure to ionizing radiation, sedentary lifestyle, depression, exposure to MMTV virus etc all can potentially increase the risk for breast cancer.
4. Features: Signs & symptoms, of breast cancer, manifest majorly in the following ways
Lump/ nodule in the breast that gets attached to the skin of the breast over time. The lump / nodule could be hard and painless with irregular edges or it could also be soft, rounded, tender and painful.
Enlarged lymph nodes in the axilla which are palpable.
Swelling of whole or a part of a breast. This is even if there is no distinct lump felt.
Retraction or thickening of the nipple(s).
Pain in the breast or nipple.
Discharge from nipple other than breast milk.
Irritation/ scaliness of skin over the breast.
Redness of nipples
Rarely, red, swollen and tender breast.
5. Screening: Is generally recommended for asymptomatic populations goal of which, as usual, is to be able to detect & diagnose breast cancer at an early stage which is potentially curable. It is mostly radiologic with mammography/ USG being instrumental in raising suspicions for further diagnostics (i.e. biopsy) that help detect breast cancer, if any, early.
6. Diagnosis: A self-examination/ clinical exam of the breast(s)/ axilla that reveals a palpable mass prompts the following diagnostics. Abnormal blood test results may be indicative of malignancy, but a follow up imaging/ biopsy is always the gold standard for accurate diagnosis.
- Blood: ER/ PR/ HER2/neu, uPA, PAI-1, CA15-3, CA27.29 etc all tumor markers are helpful.
- Imaging: Mammography/ USG Scan usually, as relevant. Again, CT Scan of abdomen & pelvis and chest, PET CT scan, bone scan etc all help detect metastasis, if any, for cancers in stage III & above.
- Biopsy: either excisional, incisional, fine needle aspiration (FNA) or core biopsy technique, as contextually appropriate, is frequently employed and a histopathological examination (HPE) thereof clinches the diagnosis and the nature of the disease.
7. Treatment: Conventional treatment includes surgery, radiotherapy, hormone therapy/ chemotherapy as deems appropriate. Simultaneously, an adjunctive or integrative naturopathic treatment with suitable complementary & alternative medicines (CAM) too can help improve clinical outcomes and facilitate recovery as would be feasible contextually.
8. Prognosis: Preventive measures, earlier diagnosis and right early treatment is key for an effective therapeutic management & better prognosis. Like most other cancers, the chances of cure for an early stage breast cancer are more. The cure/ recovery chances are influenced by the type, grade, stage of cancer, recurrence and the patient’s general health & vitality etc all. Above-mentioned apart, age, menopause status, lymph node status, ER/ PR/ HER-2/ neu status, size & extent of breast cancer etc all also influence the treatment outlook in breast cancer. The five year survival rate is strongly correlated with the stage of breast cancer.
9. Prevention: Rightly said, prevention is always a better choice. Although genetic risks are difficult to modify, still an increased focus on protective factors and avoidance of the risk factors can be of help. An adherence to a Mediterranean diet, maintaining an ideal body weight and an active lifestyle with due emphasis on regular exercising (for at least 30 minutes daily), de-stressing and relaxation is highly recommended for reducing the risks of breast cancer. A healthy eating plate comprises essentially a low fat diet, fibre rich foods including whole grain cereals, green leafy vegetables cooked using healthy vegetable oils, fresh fruits of all colours as seasonally available and healthy proteins/ fats including fresh fish, poultry, beans, nuts etc all. It is advisable to limit milk/ dairy, preferably of low fat content, to 1 to 2 servings max daily. Although alcohol is optional and is not for everyone, the consumption of the same, if any, has to be strictly in moderation, and is best avoided. Smoking is to be avoided as well. Again, red meat, butter, refined grains, sweets, sugary drinks including carbonated beverages and other high calorie foods etc all, if any, are to be taken sparingly or are best avoided too. Limiting dosage/ duration of hormone therapy, if any, especially to counteract post menopausal symptoms and also avoiding exposure to radiation and environmental pollution can help reduce the risks of breast cancer. Apart from the above-mentioned, for high risk cases, a prophylactic oophorectomy, prophylactic radical mastectomy, long term hormone therapy etc all can help reduce the chances/ risks of developing breast cancer significantly. Breastfeeding is known to confer protection against breast cancer risk too.
Is there any other possible cure for herniated disc except operation when the patient has started losing power in one leg while other leg is having radiative pain.
I have been suffering from disk problem since 7 months. I have consulted a doctor. I took x-Ray as per his advice. He said disk has been narrowed. He prescribed some painkillers and vitamin tablets. Could anyone please prescribe some medicine for me. I am really unable to sit without any support.
My husband hs cirrhosis of liver stomach very distended+an ugly umbilical hernia+very dry skin+rash on legs +occasionally loose motions+disinterested in everything+lathargy+very weak+no energy+ frequent urination at nite with the result doesnt sleep well at nite. Medications urimax, lasilactone, lasix, heptapro. Are all these symptoms related to the cirrhosis. Latest sonography report shows right lobe of liver is contracted n left lobe is enlarged with coarse bright echogencity with nodular surface. Intraheatic biliary radicles normal. Cbd normal. Portal vein is patent. Gallbladder is distended with no calculi or polyps spleen is borderline enlarged. Free fluid is noted approximately 200cc impression cirrhosis of liver borderline splenomeagly. Cortical calcific speck in both kidney s free fluid 200cc can you tell how serious is this condition his sodium is low 126.
I am 24yr old male and have backache for 7 month. My mri report is mild annular disc bulge is seen at l4-5 level with subtle anterior thecal sac impression. What should I do?
I have cervical small disc bulge and disc protrusion inserting thecal sac. Is there any permanent cure in ayurveda?
One of the things that Shannen Doherty and Rita Wilson, the wife of Tom Hanks, have in common, apart from their fame is that both were affected by breast cancer. No matter how normal a person may seem, breast cancer can strike anyone. In fact, it usually strikes one in eight women. So, it makes good sense to know what it can appear as!
Breast cancer(स्तन कैंसर) makes up a rather big amount of the general cancer cases as 15% of the cancer cases which are reported on a yearly basis are usually breast cancer cases. That being said, there are quite a few things which can be done in order to reduce a person’s risk to breast cancer.
Prevention is Prudent-
Get Fit: The first thing which should be done is that a reasonable level of fitness should be maintained. Many studies have found that if a person is significantly heavier than her recommended weight, she is at a far great risk to develop all sorts of cancer and breast cancer, in particular, than a person who is able to keep her weight in check. The difference in cancer risk rates is about 40%. This is because a greater amount of fat leads to more estrogen being produced, which increases the risk of breast cancer.
Quit Smoking: While most people associate smoking as something which increases the risk of cancer to the lungs and are not aware that it increases the risk of breast cancer, too. So, the best solution is to kick the habit!
Get Off the Pill: Once a woman crosses past her mid-thirties, she should try to avoid relying on birth control pills to reduce the risk of pregnancy. This is because these pills have an effect which increases the risk of breast cancer, which heightens as a woman gets older. As long as the woman cuts out the use of the pill, the risk quickly gets cut, as well.
Get Regular Check Ups: While screening for breast cancer by making use of mammograms does not cut the risk of it, the screening helps detect breast cancer early if it does exist. As a result, a woman has a much better chance of fighting breast cancer. So, a woman who is past the age of forty should try to have a mammogram on an annual basis with the frequency of the same increasing as she gets older. However, it is to be kept in mind that going for a mammogram too often is also not a good idea as the tests themselves pose risks of DNA changes.
Women all around the world are susceptible to breast cancer. While there isn’t a 100% chance of avoiding it, taking care of yourself and leading a fit and active lifestyle can significantly cut down your risk of contracting this condition. Remember, your health is in your hands, so the earlier you start, the better! If you wish to discuss about any specific problem, you can consult a gynaecologist.
The thought of going under the knife to treat your spine problem may give rise to a range of emotions; make you ponder over a number of things such as the recovery period, procedure and techniques involved and so on. Nonetheless, before opting for the surgery, there are certain points that you should go over and these are:
- Be well aware of the cause of your pain - Identifying the cause that is behind your pain is vital in order to decide whether the surgery is going to prove beneficial in the long run or not. If the cause is not identified as the right one, the surgery may prove futile and you may not get the pain relief that you're looking for.
- Gather detailed information about your spine surgeon - Before visiting the spine surgeon, you should collect detailed information about the specialist so as to be able to come up with appropriate questions concerning the surgery. From questions concerning about the surgeon's success and complication rates, numbers of surgeries performed to qualifications of the surgeon, these and much more should be part of your evaluation process.
- Prepare yourself before a consultation - It's good to prepare yourself before a medical consultation. Whether it's researching about the surgery and your condition or being well aware of your family's medical history, or details about the pain that you experience, or your expectations from the surgery, every aspect should be covered so that you derive the maximum benefit from your meeting.
- Carry out your own research - Carrying out your own research on the alternatives before opting for the surgery can put you on a better footing. It's imperative to compare the opinion put forward by the surgeon from genuine sources so that you're better able to understand the merits and demerits of the treatment. If you wish to discuss about any specific problem, you can consult an Orthopedist.
I am 42 year old female .After slip disc L1toL4 problem, pain in left heel and becomes severe at times. Is it spur in the foot ,slip disc or something else.
I am 34 years old male. I am suffering from back pain for the last 3 years. I have done MRI. In MRI it is found that 1. MILD DIFFUSE DISC BULGE IS NOTED AT L3-4 LEVEL CAUSING ANTERIORTHECAL SAC indentation MINIMAL NARROWING OF BILATERAL NEURAL forminal AS WELL AS LATERAL RECESSES. 2. MILD DIFFUSE DISC BULGE IS NOTED AT L4-5LEVEL CAUSING ANTERIOR THECAL SAC INDENTATION AND NARROWING OF BILATERAL NEURAL forminal AS WELL AS LATERAL RECESSES. MILD facial ARTHROPATHY IS NOTED BILATERALLY. please MAKE ME UNDERSTAND WHAT IS THE PROBLEM AND WHAT IS THE SOLUTION.
1. You felt a lump in your breast and it always means you have breast cancer.
It's a small percentage of breast lumps only that will turn out to be cancer. If you discover a persistent lump in your breast or notice any changes in breast tissue, never ignore it. You must see a physician for a clinical breast examination. He or she may possibly order breast imaging studies to determine if this lump is of concern or not.
Take charge of your health by performing routine breast self-exams, establishing ongoing communication and counseling with your doctor, getting an annual clinical breast exam, and scheduling your routine screening mammograms.
2. Only women get breast cancer, men do not.
Quite the contrary, each year it is estimated that approximately 2,190 men will be diagnosed with breast cancer and 410 will die. While this percentage is still small, men should also check themselves periodically by doing a breast self-exam while in the shower and reporting any changes to their physicians.
Breast cancer in men is usually detected as a hard lump underneath the nipple and areola. Men carry a higher mortality than women do, primarily because awareness among men is less and they are less likely to assume a lump is breast cancer, which can cause a delay in seeking treatment.