Dr. Pushparani

Causes and Symptoms of Hemophilia

Hemophilia is a genetic disorder, which is marked by improper blood clotting. In this bleeding disorder, a person suffers from low levels of certain proteins called clotting factors, which aid in the process of blood clotting. There are 13 types of factors that combine with platelets to help in the formation of a blood clot. People who suffer from hemophilia start bleeding due to minor reasons and their blood takes a very long time to clot.

Causes of Hemophilia

Depending on the type, the causes of hemophilia can vary. There are three types of hemophilia, namely hemophilia A, B, and C.

• Hemophilia A, the most commonly occurring form, is caused by a deficiency of factor VIII.
• Hemophilia B, also known as Christmas disease, is caused by the lack of factor IX.
• Hemophilia C, on the other hand, occurs due to the lack of factor XI.

However, hemophilia is a genetic condition, which usually passes down from generation to generation. A defect in the genes, which causes the body to make factors VIII, IX, or XI causes the condition. These particular genes are located in the X-chromosomes and, thus, it makes hemophilia an X-linked recessive disorder.

What are the symptoms of hemophilia?

The intensity of symptoms would depend upon the seriousness of the factor deficiency. A person with a serious deficiency may bleed for no apparent reason, which is also known as spontaneous bleeding.

Some of the symptoms of this bleeding disorder are:

- Blood in the urine and stool
- Large, deep bruises
- Excessive bleeding
- Bleeding gums
- Frequent nosebleeds
- Pain and stiffness in the joints
- Irritability and anxiety
- Severe headaches
- Repeated vomiting
- Neck pain
- Cloudy or foggy vision
- Extreme sleepiness

'Consult'.

Tip: Does Your Blood Group Make You Prone To Certain Health Issues?

Vulvodynia is generally identified as a condition, which causes chronic back pain or vulvar pain, but having no identifiable cause. The causes as well as the nature of the condition are very obscure, and until recent times, it had never been considered to be an actual pain syndrome. What is commonly affected is the vulva, or the external female genital organs, consisting of the clitoris, labia and the vaginal opening.

Generally, there are two types of vulvodynia:

1. Generalized Vulvodynia: this can mean pain in any part of the Vulva occurring erratically at different times
2. Vulvar vestibulitis syndrome: this is limited to the vestibule, or the vaginal opening. It has similar characteristics of a burn, and pain can be incurred only when contact is made, say during sexual intercourse.

Symptoms
Although not life threatening, signs and symptoms of Vulvodynia can still cause a ton of problems for women. They can create much complication when it comes to daily activities as well as other feelings, like sexual frustration, agitation, depression and low self-esteem.

Symptoms can be very erratic and can occur once in a while or all the time. They may be limited to just one specific area or can affect the entire vulva, interfering with daily activities such as walking, exercising and sexual intercourse.

Here are some common signs and symptoms:

1. A burning or stinging sensation
2. An aching or throbbing sensation
3. May swell and you may experience soreness;
4. Severe itching and agitation

Causes
Because the causes are not identifiable, extensive research is still going on in order to decipher the nature of the syndrome. A few possible causes may include:

1. Nerve irritation or injury
2. Genetic abnormalities
3. Muscle spasms
4. Hormonal changes
5. Abnormal responses to infections or traumatic injuries
6. Hypersensitivity to yeast infections
7. Allergies to certain chemicals or substances
8. History of sexual abuse
9. Frequent antibiotic use