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Dr. Vikram D. Sanghvi

Oncologist, Mumbai

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Dr. Vikram D. Sanghvi Oncologist, Mumbai
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Personal Statement

I pride myself in attending local and statewide seminars to stay current with the latest techniques, and treatment planning....more
I pride myself in attending local and statewide seminars to stay current with the latest techniques, and treatment planning.
More about Dr. Vikram D. Sanghvi
Dr. Vikram D. Sanghvi is a trusted Oncologist in Mumbai, Mumbai. He is currently practising at Bombay Hospital & Medical Research Centre in Mumbai, Mumbai. Book an appointment online with Dr. Vikram D. Sanghvi on Lybrate.com.

Lybrate.com has an excellent community of Oncologists in India. You will find Oncologists with more than 38 years of experience on Lybrate.com. You can find Oncologists online in Mumbai and from across India. View the profile of medical specialists and their reviews from other patients to make an informed decision.

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English
Hindi

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Bombay Hospital & Medical Research Centre

#117, Marine Lines. Landmark: Next To Liberty Cinema, MumbaiMumbai Get Directions
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Can person sufferings from blood cancer can be cured by bone marrow transplant? If yes how it can be possible?

European Society for Medical Oncology certification, DM - Oncology, MD - General Medicine, MBBS
Oncologist, Faridabad
The term bone marrow transplant is actually a misnomer in the present context as transplant is now conducted by harvesting stem cells from the blood of the donor. So the correct and logical term now is peripheral blood stem cell transplant. This is just like a blood donation for the donor and poses no risk at all to the donor. The term blood cancer is generally used for leukemias, these can be of two types - acute and chronic. For the chronic leukemias, specially chronic myeloid leukemia, stem cell transplant is now generally not required as drugs like imatinib, dasatinib and nilotinib are extremely effective. For chronic lymphocytic leukemia too transplant is rarely done these days and is generally reserved for relatively younger patients. Even in the imatinib era transplant is an effective procedure and can cure patients with cml (chronic myeloid leukemia) who do not respond to imatinib and other tyrosine kinase inhibitors. For acute myeloid leukemias stem cell transplant is recommended for all cases except the low risk cases, after completion of chemotherapy. Risk is defined based on kind of genetic mutations in the leukemic cells for acute lymphoblastic leukemia transplant is generally done at relapse, but certain genetic mutations necessitate an earlier transplant, so does presence of or increase in minimal residual disease, which signifies cancer cells not visible to the human eye under the microscope. Procedure of stem cell transplant hla matching is done between patient and siblings. Best match is selected as a donor. Matched sibling is the most commonly used donor in blood cancers. In many cases a match is not available, for such cases matched unrelated donor, cord blood, or a partially matched donor (haploidentical donor) is sometimes selected. Donor is given growth factor injection subcutaneously to bring out the stem cells from the bone marrow to bloodstream, twice daily for 5 days. After that the stem cells are collected and stored. Patient is given high dose chemotherapy to kill cancer cells as well as his normal marrow. After chemotherapy, donor stem cells are injected into the body of patient from a vein. After approximately 11-14 days the donor cells get engrafted in the patient's marrow and start producing normal blood cells. The donor cells also kill the cancer cells and prevent cancer from coming back. Overall depending on whether the patients cancer is controlled or not before transplant the cure rate after transplant can vary from 60 % for patients who have a good control and less aggressive disease biology, to less then 20 % in patients with uncontrolled disease before transplant. Overall, approximately 40 % patients get cured with a transplant. Upto 40 % patients can develop complications, and half of these may be very severe and life threatening. This figure is more in mismatched transplants. Apart from complications, there is still a risk of relapse and these patients need close monitoring in the first few years after transplant.
15 people found this helpful
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What is fibroadenoma? Is this any serious health issue? What should be done to git rid of this?

MBBS
General Physician, Delhi
A fibroadenoma is a non-cancerous tumor in the breast that is commonly found in women under the age of 30. The exact cause of fibroadenomas is not known. Hormones such as estrogen may play a part in the growth and development of the tumors. Taking oral contraceptives before the age of 20 has been associated with a higher risk of developing fibroadenomas.
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Cancer Alert: Know Symptoms That Could Be Cancer

MS ( General Surgery)
Oncologist, Mandsaur
Cancer Alert: Know Symptoms That Could Be Cancer
Cancer symptoms you shouldn't ignore

Most often than not, cancer comes unannounced and rocks our world. While of late routine tests are being encouraged, it is advisable to keep a look out for symptoms which are commonly overlooked. Some of them are:

1. Peculiar back pain - it has been noticed that the first symptom for liver cancer in many cases is pain the back of the lower back side of the body. Back pain could also be a symptom for breast cancer, in cases where the tumour is pressing backwards, into the chest.
2. Unexplained nail marks - nails often reflect the condition of our health. If there is a sudden and unexplained change in the fingernails, like maybe a dot/a black mark or a brown mark under the nail, this could be a sign of lung cancer.
3. Sensitive skin patches - if there is a lump on the skin or a patch feels sore, is crusty or bleeds very easily then this could be a symptom of skin cancer. It is important to be aware of all changes in your skin, throughout the body.
4. Unexplained facial puffiness - if your face seems puffy, read or swelled, without any logical explanation, this could be a symptom.
5. Unusual menstruation - if you are having unusually heavy and painful periods, it is advisable to request for a transvaginal ultrasound as this could be a symptom of uterine cancer.
6. Changes in breast (s) - this is the most common change which women who have been diagnosed of breast cancer have reported. If the nipple is flattened, inverted or turned sideways, it could be a symptom for breast cancer. Also, if the breast feels read, sore or swollen, it could be a symptom.
7. Frequent stomach problems - frequent upset stomachs and cramps could be the symptom of colorectal cancer.
8. Unreasonable weight loss - if you are losing a lot of weight without even trying to, this could be an early sign of colon or any other digestive cancer. It could also mean that the cancer is spreading to the liver, if your appetite is getting affected.
9. Blood in stool - if there is blood in your stool, this could be a symptom of colorectal cancer and you need to go for a colonoscopy.

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107 people found this helpful

My friend is suffering from cancer, Recently diagnosis heart problem i.e irregular heart beet & High Triglyceride. Have any suggestion? If any relation between cancer treatment & heart attack.

MBBS, DNB ( Radiation Oncology)
Oncologist, Mumbai
My friend is suffering from cancer, Recently diagnosis heart problem i.e irregular heart beet & High Triglyceride. Ha...
If your friend is undergoing some chemotherapy, the heart problem could be due to some chemotherapeutic drug. Or it could be due to already pre existing heart disorder.
2 people found this helpful
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What is blood cancer symptoms, as I am suffering from heavy heartache for 1 month. Please kindly advice me wha to do. I m really afraid as one of my friend told me it could be blood cancer.

MBBS, MD - Medicine, MD - Oncology
Oncologist, Delhi
Heartache is caused by faliure in love affair. Please take care about it. We can talk about blood cancer latter after you have treated your heartache.
1 person found this helpful
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BDS
Dentist, Cuttack
Most of oral ulcers natural remedy are HONEY AND DESI GHEE. Just appky it wth finger

Frequent Urination - Can it be a Sign Enlarged Prostate

M.Ch - Urology, MS, MBBS
Urologist, Dehradun
Frequent Urination - Can it be a Sign Enlarged Prostate

The condition of enlarged prostate occurs due to the enlargement of a man’s prostate gland, with the passage in time. Also known as benign prostatic hyperplasia (BPH), it is more common in men over the age of 60. Some cases might have symptoms and others may be symptomless. Although the causes are relatively unknown, it is evident that BPH is not a form of cancer, neither does it cause cancer. The prostate is located below the bladder and is responsible for producing the fluid needed by semen. The growth of the prostate tissue that is associated with benign prostatic hyperplasia begins near the inner prostate which is a tissue ring around the urethra. Its growth is generally inward.

Causes
It is of common knowledge that in males, the urine originates from the bladder and flows through the urethra. BPH is a condition where the prostate experiences a benign i.e. non cancerous enlargement which leads to blockage of urine flow through the urethra (the urinary duct). The resultant enlargement, caused due to the gradual multiplication of cells, subjects the urethra to extra pressure. Further narrowing of the urethra causes more contraction of the bladder, resulting in the urine being forcefully pushed out of the body.

With time, the condition leads to the bladder muscles gradually becoming thicker, stronger and oversensitive. Contraction occurs even due to the presence of small amounts of urine, giving rise to frequent needs of urination. At one point, the bladder muscle is unable to overcome the effects of the narrowed urethra. Due to this, urine does not pass properly and the urethra is not emptied.

Some of the common symptoms of enlarged prostate include:
1. Frequent urination
2. Urgency to urinate
3. Difficulty during urination
4. A slow or weak urinary stream
5. Requirement of extra effort to urinate
6. Interrupted sleep due to need of urination

Further risks
Sometimes, when the bladder is not emptied completely, a risk of urinary tract infections develops. Some other serious problems which can be a result of enlarged prostate include blood in urine, bladder stones as well as acute urinary retention (inability to urinate). In some rare cases, kidney and/or bladder damage might also result from such a condition. If you wish to discuss about any specific problem, you can consult a doctor and ask a free question.

1847 people found this helpful

When rectum removed for rectal cancer surgery nd colostomy done dan aftr chemo therapy is pouch surgery done is it possible.

DNB, MBBS
Oncologist, Faridabad
Dear mam it depends on the type of surgery done according to the location of tumour. In APR surgery, it is a permanent colostomy and in anterior resection it is temporary and can be closed after completion of treatment.
1 person found this helpful
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I have symptoms of enlarged Prostate and these are linked to my difficulty in urination, where either I have a weak stream or get a sudden urge for urination and not able to empty the bladder. Additionally I get severe ache in the left kidney while passing urine, forcing me to at time withhold passing of urine. Though this not happen every time. All xray or ultra sounds in the past have not revealed any stone of any kind. Do you think the pain is due to non emptying of the bladder. What should be my line of treatment. Thank you for your advice.

Fellowship of the Royal College of Surgeons (FRCS), MS - Urology, MBBS
Urologist, Ahmedabad
I have symptoms of enlarged Prostate and these are linked to my difficulty in urination, where either I have a weak s...
Dear , before I suggest I would like see your reports especially usg and that too post-void residual urine. It is very likely that you have bladder neck obstruction. Also get uroflowmetry done. It is woth while to try alpha blockers like tamsulocin or doxazocin. Please post your reports Dr. Kiran mehta.
1 person found this helpful
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My teenage sister want to use nail polish, but I have heard that many nail polishes contain formaldehyde and can cause cancer. Is it safe for my sister to use it?

DNB, MBBS
Oncologist, Faridabad
Not all the nail paints contain formaldehyde, it is harmful for the workers working in nail paint inndustry, not by application once in while.
40 people found this helpful
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