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Dr. Ustad Parekh

Ophthalmologist, Mumbai

800 at clinic
Dr. Ustad Parekh Ophthalmologist, Mumbai
800 at clinic  ·  ₹ online
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Personal Statement

I'm dedicated to providing optimal health care in a relaxed environment where I treat every patients as if they were my own family....more
I'm dedicated to providing optimal health care in a relaxed environment where I treat every patients as if they were my own family.
More about Dr. Ustad Parekh
Dr. Ustad Parekh is one of the best Ophthalmologists in Bombay Hospital, Mumbai. He is currently associated with Zain Eye care in Bombay Hospital, Mumbai. Save your time and book an appointment online with Dr. Ustad Parekh on Lybrate.com.

Find numerous Ophthalmologists in India from the comfort of your home on Lybrate.com. You will find Ophthalmologists with more than 25 years of experience on Lybrate.com. You can find Ophthalmologists online in Mumbai and from across India. View the profile of medical specialists and their reviews from other patients to make an informed decision.

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Hindi

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3-D, Kakad Hpuse, Sir V Thackersey Marg, , Marine Lines Landmark: Opposite Bombay Hospital, Opposite Liberty Cinema, MumbaiMumbai Get Directions
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I have red sore eyes, it pains every night when I go to sleep. What do I do to get rid of this.

BHMS
Homeopath
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I have red sore eyes, it pains every night when I go to sleep. What do I do to get rid of this.
Hello, get your eyes tested from an opthalmologist. Include the following for getting better vision: vitamins a, c, e, and minerals like copper and zinc are essential to eyesight. Get the antioxidants from dark leafy greens, egg yolks, yellow peppers, pumpkin, sweet potatoes, and carrots. Include garlic and onions. Blueberries, grapes as they have antioxidant and anti-inflammatory properties that can help improve your vision. Dha is a fatty acid found in coldwater fish like salmon, sardines and mackerel. Exercises for strengthening eye muscles: -begin by partially closing your eyes; the lids should only be halfway shut. After holding for 10-15 seconds, close your eyes very slowly. Take a few deep breaths to increase oxygen in the blood. -warm your eyes. Rub your palms together to create heat, and then place them against your eyes for five seconds. Repeat this three times. -hold a pen at arm's length. Focus your gaze on the tip of the pen. Bring the pen closer to your nose at a slow and steady pace. Repeat this exercise 5-10 times. -concentrate your vision on the tip of your nose. Then shift your gaze to an object further away, either at arm's length or 20 feet away. Then shift your eyes back to the tip of your nose. Repeat this exercise 10 times. Insufficient sleep may weaken your vision, so shoot for 8 hours of sound sleep a night. Rest your eyes 10 minutes for every 50 minutes spent reading or in front of the computer. If your eyes feel overly tired, lie down and place cooling cucumber slices over your eyelids. Medication: take homoeopathic medicine which will help you in preventing first and then reducing the power of your eyes (if the eye power is less). Take physostigma 6/ thrice daily for 1 month and instill euphrasia eye drops twice a day. Thereafter, revert back for further guidance.

Hello, I am about 17 years old. My eyesight is weak its about 5.25. I want to remove specs. What precautions should I take and which medicine did I take.

Fellowship in Comprehensive Ophthalmology, DOMS
Ophthalmologist
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Hello, I am about 17 years old. My eyesight is weak its about 5.25. I want to remove specs. What precautions should I...
There is no medication or food or acupressure for improving eyesight or to get rid of glasses. If not interested in glasses then you can try a. Contact lens b. Lasik laser as your age is now 17 years so your number will not increase much now whether you wear glasses or not as number becomes stable at age of 18-20 yrs. Having said that I advise you to eat balanced diet including green vegetables and seasonal fruits for keeping eyes and body healthy. As you are not comfortable with contact lens then go for lasik. Lasik is a very easy and painless procedure. If you want to get rid of glasses then go for lasik. Having said that, results for hyperopic lasik are not very good. My advice is that you continue using glasses.

I am getting recurrent eye sight within 2 week gap, this is the third time I am getting an eye sight. Can it be because my eye vision has weakened? What should I do? Till now I have perfect vision.

MBBS, MS - Ophthalmology, Fellowship in Vitreoretinal Surgery
Ophthalmologist
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I am getting recurrent eye sight within 2 week gap, this is the third time I am getting an eye sight. Can it be becau...
Get a dilated refraction done and a complete check up by an ophthalmologist. You may have hypermetropiawhich often leads to such problems. Thanks.

I have red eyes for 1 week then what should I do I don't know what am I doing in night time my eye not visible correctly so please help me sir.

FPRS, DNB Ophtalmology
Ophthalmologist
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I have red eyes for 1 week then what should I do I don't know what am I doing in night time my eye not visible correc...
Dear lybrate user, red eyes could be because of many reasons but commonly it is due to allergy or infection. You need to visit eye specialist to differentiate between the two as the treatment is different. Also get your eyes checked for any glass power

Hi doc my question for you is that my eye power is minus 6.75. I have to do a lot work on computer. Sometime my right eye lid flick a little. Kindly provide me some solution and help me out. Thanks in advance.

FPRS, DNB Ophtalmology
Ophthalmologist
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Hi doc my question for you is that my eye power is minus 6.75. I have to do a lot work on computer. Sometime my right...
Take frequent breaks while you are working every 20-25 mins take break to look away from screen blink more frequently' level of screen should be below the level of eyes ac should not blow directly on your face. Also get your eyes checked for any change in spectacle power.

I am 25 years old I having Cataract in both eyes becoz I am taking perdisionl bcoz of that side effects. I want to knw that how much time surgery of cataract can by delay?

Fellowship in Comprehensive Ophthalmology, DOMS
Ophthalmologist
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I am 25 years old I having
Cataract in both eyes becoz I am taking perdisionl bcoz of that side effects. I want to kn...
Hello cataract surgery is not an emergency you can wait till it starts affecting your daily routine.
1 person found this helpful

I have been suffering from seasonal allergic conjunctivitis every year at the onset of summer. Tried olopatadine 1 od together with cmc gel qds for 15 days. Hardly any significant relief. Please help me.

FRCS - I & II , FICO, MS - Ophthalmology
Ophthalmologist
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I have been suffering from seasonal allergic conjunctivitis every year at the onset of summer. Tried olopatadine 1 od...
Respons in allergic conjunctivitis is very variable. Controlled longterm treatment is usually required. For more specific reply appointment will be helpful.

I am a student how can I loss my weigh and also want to gain about some height and also a greater vision?

M.Sc - Dietitics / Nutrition
Dietitian/Nutritionist
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I am a student how can I loss my weigh and also want to gain about some height and also a greater vision?
Burn fats and calories healthy diet to lose weight leave carbonated beverages eating vegetables to lose weight eating fruits to lose weight stop eating sugar lose weight fast reduce sodium lose weight herbal tea to lose weight eat low calorie foods drink plenty of water avoid sweets eat more vegetables you need to take a balanced diet for greater vision see green things like trees and est more vegetables do exercise.
1 person found this helpful

She Is a software employee. She used to sit in front of system fr nearly 10 hrs. Because of this her eye sight is being increased. Any special glasses are recommended .plz.

Fellowship in Comprehensive Ophthalmology, DOMS
Ophthalmologist
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She Is a software employee. She used to sit in front of system fr nearly 10 hrs. Because of this her eye sight is bei...
Hello Prolonged working on laptop/TV/mobile can cause computer vision syndrome. Computer vision syndrome is a condition resulting from focusing the eyes on a computer or other display device for, uninterrupted periods of time. Some symptoms of cvs include a. Headaches b blurred vision c. Neck pain d redness in the eyes e. Eye strain f dry eyes sometimes watery eyes these symptoms can be further aggravated by improper lighting conditions. Measures to reduce this include 1. Work under proper light. 2. Blink a lot. 3. Cold compresses 4. Use good lubricating eyedrop 5. use antiglare glasses There is no relation between use of computer and number of your glasses

I m azhar I have to ask about the health of my eyes My eyes are too weak how can I would increase my eyes power.

FICO, DNB Ophtalmology
Ophthalmologist
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I m azhar I have to ask about the health of my eyes
My eyes are too weak how can I would increase my eyes power.
There are multiple causes responsible for diminution/ blurring of vision. Let me enumerate them in brief for you: (1) refractive error. This is one of the commonest reasons responsible. Minus or plus number in one eye or both eyes may be responsible for weak/ blurred vision. The solution for this is glasses/ contact lens/ refractive surgery (if applicable). It should be checked by a trained optometrist/ ophthalmologist and proper glasses should be prescribed. (2) cornea related problem: injury, degeneration, infections or inflammation occurring on the cornea tend to causes loss of transparency and lead to weakening of vision. These should be assessed preferably by a cornea specialist and treated appropriately. (3) cataract in the lens of the eye: this usually occurs with increasing age but in some cases may occur at a younger age. There are multiple systemic factors responsible (eg. Diabetes, increased cholesterol levels, etc) injury to the eye may also cause cataract. This should be assessed and treated appropriately by a cataract specialist. (4) retina/ vitreous problems: these occur due to a variety of reasons such as high minus numbers, diabetes, trauma, etc. These issues are best assessed and treated by a retina specialist. There are good quality surgical options available for the same. (5) optic nerve related problems: these may occur due to raised eye pressure (glaucoma), or occur in association with certain conditions related to the brain and the blood vessels. These are best assessed by a retina/ glaucoma specialist (whichever applicable). (6) neurological problems: certain problems in the brain and the central nervous system tend to cause weakening/ blurring of vision. These are best assessed by an eye specialist in concordance with a neurologist and a neurosurgeon if required. Thus, based on the category you fall under, it would be necessary to take appropriate help and treatment. If you have a high refractive error (power of glass) you could consider undergoing refractive surgery. Operations done to remove the refractive error (power) of the eyes are known as refractive surgery (lasik). There are certain basic criteria that most patients need to fulfill before they can safely undergo refractive surgery. To enumerate, they are: (1) stability of refraction: the power of the eyes should have become stable for a period of 1.5 years minimum without any change. (2) curvature of the cornea should be tested by a technique which is known as topography. (3) thickness of the cornea should be measured by a test known as pachymetry. The minimum thickness required is 550 microns. (4) dilated retina evaluation: this is one of the most important tests that should be performed by a trained retina specialist. This test helps in detection of any offensive lesion on the central or peripheral retina. In case of any retinal abnormality, these should be treated before undergoing the surgery for number reduction. (5) there should be no pre-existent corneal abnormality. (example: corneal scar, opacity, defect, etc.) another important suggestion is that whenever you go for the assessment (the above mentioned tests), you should discontinue the use of contact lenses at least 4 weeks prior to the assessment. The reason for this being that use of contact lens temporarily alters the contour of the cornea. It takes around 3-4 weeks for the restoration of the original corneal contour after removal of the contact lens. Another important point is that you, as a patient, should be compliant to put post operative medication in your eyes for at least 2 months. There is bound to be some discomfort, watering, foreign body sensation, pain after the surgery in most cases-you should be ready to tolerate that. A leave from work for 7-10 days after the surgery should be generally sufficient. Last but not the least, you should set realistic expectations from this surgery. Though extremely rare, there is a remote possibility that the surgery may need to be repeated. Also, the need for subsequent treatment for the eye may be required. Thus, you should be compliant enough to trust and follow your eye specialist. In case you have any other queries, feel free to contact me via the audio/ video facility offered by lybrate. Hope my suggestions help you, take care,

Hello my eyes no 2.5 and 2.25 tell me can I use any eye drop that can be improve my a eyes.

BHMS
Homeopath
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Hello my eyes no 2.5 and 2.25 tell me can I use any eye drop that can be improve my a eyes.
Hello , you can use CMD2 eye drops, 2 drop in each eye twice daily. You should these exercises daily to strengthen your eye muscles ;- Warm your eyes. Rub your palms together to create heat, and then place them against your eyes for five seconds. Repeat this three times. Roll your eyes. Start by looking up and then slowly circle 10 times clockwise and 10 times counterclockwise. Focus. Hold a pen at arm's length, focus your eyes on it, and slowly bring the pen closer until it's about 6 inches away from your nose. Then slowly move it back, keeping your eyes focused on the pen, 10 times in all. Massage your temples. Using your thumb knuckles, massage your temples in small circles, 20 times in one direction and 20 in the other. Repeat the same actions above the mid-point of the eyebrows at the forehead, then below the eyes on both sides of the bridge of the nose. Take a mini-nap. Put your head back, close your eyes, and relax for 3 minutes. Insufficient sleep may weaken your vision, so shoot for 8 hours of sound sleep a night. Rest your eyes 10 minutes for every 50 minutes spent reading or in front of the computer. If your eyes feel overly tired, lie down and place cooling cucumber slices over your eyelids. Medication: Take homoeopathic medicine which will help you in preventing rather reducing the power of your eyes. Take Physostigma 6/ thrice daily for 1 month. Thereafter, revert back for further guidance.
1 person found this helpful

I have been working late and now my right eye is paining while I blink what should I do.

DHMS (Diploma in Homeopathic Medicine and Surgery)
Homeopath
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I have been working late and now my right eye is paining while I blink what should I do.
There are many reasons of pain in your eyes and few important ones are 1. Lack of sleep 2. Weak eye sight, conjunctivitis, allergy due to loss of sleep 3. Overuse of eyes while studying, computers. And esp. In improper light so visit an ophthalmologist to identify the cause of your eye pain and blinking as most of the time it signifies weak eyesight. You can use following homoeopathic eyedrops for general eye pain cineraria euphrasia eye drops.
1 person found this helpful

Right side of my eye is vibrating please help its happening continuously since a month.

Fellowship in Comprehensive Ophthalmology, DOMS
Ophthalmologist
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Right side of my eye is vibrating please help
its happening continuously since a month.
Hello Your symptoms are suggestive of myokymia most common cause being tension kindly observe it may resolve on its own without treatment if it persists, kindly consult local ophthalmologist This is a provisional diagnosis. Consult your ophthalmologist for detailed examination.
1 person found this helpful

I am suffering from fever, malaria, red eyes, red urine and cold from last 10 days. What should I do? What precaution should I take?

MBBS
General Physician
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I am suffering from fever, malaria, red eyes, red urine and cold from last 10 days. What should I do? What precaution...
You should consult a doctor so after examining you physically a and clinically the doctor will assessment for further management.

Hello My problem is my eye's Ye kabi kabi bahut dard karty Bahut tablet's li par koi fark nahi pada please help me.

MS - Ophthalmology
Ophthalmologist
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Hello

My problem is my eye's Ye kabi kabi bahut dard karty Bahut tablet's li par koi fark nahi pada please help me.
Dear lybrate user:- you r suffering from refractive error. You need urgent correction of refractive error. Take regullar aerobic exercises, coloured fruits & vegetables, plenty of water.
2 people found this helpful

What does the term" cataract mature mean. Pl explain. How long can one wait to get the cataract operated?(i've been diagnised with cataract 2 months ago? Please Advise.

Fellowship of the Royal College of Surgeons (FRCS), Cornea Fellowship, FICO, DOMS, MBBS
Ophthalmologist
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One can wait as long as a few years depending on the stage of the cataract and vision of the patient. Best way is to ask your doctors advise. Dr. Rishi swarup

My eye power is 4.5 and 5 myopia. I am 25, will it still increase ? I heard power stop increasing after 21-22 yrs of age. I think its increasing slowly. I have to spent lot of time studying and on computer. Please reply asap

Ophthalmologist
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Yes its true that power usually stabilizes at around 20 years of age. But in case of high myopia , like your aunt, power can vary and increase very slowly for long. You need not to worry . The only imp thing is that complete eye check up with retina examination is all that is required.

One elderly person told me to put raw potato drops into my eyes to improve my vision. He was told by a saint in haridwar. Do you think it will work?

Fellowship in Comprehensive Ophthalmology, DOMS
Ophthalmologist
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One elderly person told me to put raw potato drops into my eyes to improve my vision. He was told by a saint in harid...
Hello. Please do not try things. It may damage your eyes hello. There is no medication or food for improving eye sight or to get rid of glasses. Get your vision tested and wear glasses. If not interested in glasses then you can try a. Contact lens b. Lasik laser as your age is now 25 years so your number will not increase now whether you wear glasses or not as number becomes stable at age of 18-20 yrs. Having said that I advise you to eat balanced diet including green vegetables and seasonal fruits for keeping eyes and body healthy. Lasik is a very easy and painless procedure. If you want to get rid of glasses then go for lasik.
1 person found this helpful

I am 55 yrs old man suffering from physicists from last two yrs. What to do.-with taking steroids facing problems like weakness, developed cataract in eyes etc etcpl advise.

MD - Ophthalmology
Ophthalmologist
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I am 55 yrs old man suffering from physicists from last two yrs. What to do.-with taking steroids facing problems lik...
Steroids are like 2 edged swords, if required for medical reasons one has to take it and yes weakness and bone weakness treated with oral tablets and cataracts will anyways require surgeries.

Dengue Vaxia

M.B.B.S,C.C.A,D.C.A,AASECT,FPA,AAD,M.I.M.S
General Physician
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Dengvaxia - first vaccine against dengue

Dengvaxia is a vaccine used to help protect adult or children against dengue disease caused by dengue virus serotypes 1, 2, 3 and 4. Dengvaxia is given to adults, adolescents and children 9 through 45 years of age living in endemic areas.

Read more:

Dengue symptoms and what to do if you think you have denguedengue fever - remedies using papaya leaf juice

Full prescribing info - dengvaxia

Contents

Dengue tetravalent vaccine (live, attenuated).

Indications / uses

Dengvaxia is a vaccine used to help protect adult or children against dengue disease caused by dengue virus serotypes 1, 2, 3 and 4. Dengvaxia is given to adults, adolescents and children 9 through 45 years of age living in endemic areas.

Dosage / direction for use

The patient will receive 3 injections of 0.5 ml each at 6-month intervals.

The first injection will occur at the chosen or scheduled date; the second injection, 6 months after the first injection; and the third injection, 6 months after the second injection. Dengvaxia should be used according to the local vaccination schedule.

If the patient forgot an injection of dengvaxia: if the patient missed a scheduled injection, the physician will decide when to give the missed injection.

It is important that the patient follows the instructions of the physician, pharmacist or nurse regarding return visits for the follow-up injection. If the patient forgets or is not able to go back to the physician, pharmacist or nurse at the scheduled time, ask the physician, pharmacist or nurse for advice.

Administration: dengvaxia is given by the physician or nurse as an injection underneath the skin (subcutaneous route) in the upper arm.

Contraindications

Do not use dengvaxia if the patient is allergic (hypertensive) to the active substances or any of the other ingredients of dengvaxia listed in description (see description); has developed an allergic reaction after prior administration of dengvaxia. Signs of an allergic reaction may include an itchy rash, shortness of breath and swelling of the face and tongue; is suffering from a disease with mild to high fever or acute disease. In this case, the physician will postpone the administration of dengvaxia until the patient has recovered; has a weakened immune system, for example due to a genetic defect, hiv infection or therapies that affect the immune system (for example, high-dose corticosteroids or chemotherapy); is pregnant; is breastfeeding.

Use in pregnancy lactation: dengvaxia must not be given to pregnant or breastfeeding women.

If the patient is of child-bearing stage, the patient should take the necessary precautions to avoid pregnancy for 1 month following administration of dengvaxia; is pregnant or breastfeeding, the patient thinks may be pregnant or is planning to have a baby, ask the physician, pharmacist or nurse for advice before receiving dengvaxia.

Special precautions

Inform the physician, pharmacist or nurse before receiving dengvaxia if the patient is taking an immunosuppressive treatment (prednisone or equivalent to 20 mg or 2 mg/kg for 2 weeks or more). The physician will postpone administration of dengvaxia until 4 weeks after the treatment is discontinued; has experienced any health problems after prior administration of any vaccines. The physician will carefully consider the risks and benefits of vaccination.

As with all vaccines, dengvaxia may not protect 100% of persons who have been vaccinated. Vaccination with dengvaxia is not a substitute for protection against mosquito bites. The patient should take appropriate precautions to prevent mosquito bites, including the use of repellents, adequate clothing, and mosquito nets.

Fainting, sometimes accompanied by falling, can occur (mostly in adolescents) following, or even before, any injection with a needle. Therefore inform the physician, pharmacist or nurse if the patient fainted with a prior injection.

Adults above 45 years of age: adults above 45 years of age should not receive the vaccine.

Driving and using machines: no data are available on the effects of dengvaxia on the ability to drive or use machines.

Use in children: children less than 9 years of age should not receive the vaccine.

Side effects

Like all medicines, dengvaxia can cause side effects, although not all patients get them.

Serious allergic reactions: if any of these symptoms occur after leaving the place where the patient received an injection, consult a physician immediately: difficulty in breathing, blueness of the tongue or lips, a rash, swelling of the face or throat, low blood pressure causing dizziness or collapse.

When these signs and symptoms occur they usually develop quickly after the injection is given and while the patient is still in clinic or physician's surgery.

Serious allergic reactions are very rare (may affect up to 1 in 10, 000 people), after receiving any vaccine.

Other side effects: the following side effects were reported during clinical studies in children, adolescents and adults (from 9 to and including 60 years of age). Most of the reported side effects occurred within 3 days after the injection of the vaccine: very common (may affect more than 1 user in 10): headache, muscle pain (myalgia), generally feeling unwell (malaise), feeling of weakness (asthenia), injection site pain, fever.

Common (may affect up to 1 user in 10): injection site reactions: redness (erythema), bruising (hematoma), swelling, and itching (pruritus).

Uncommon (may affect up to 1 user in 100): infections of the upper respiratory tract, dizziness, sore throat (oropharyngeal pain), cough, runny nose (rhinorrhea), nausea, skin eruption (rash), neck pain, hardening of skin at the injection site (injection site induration).

Additional side effects in adults (from 18 to and including 60 years of age): uncommon (may affect up to 1 user in 100): swollen glands (lymphadenopathy), migraine, joint pain (arthralgia), flu-like symptoms (influenza-like illness).

Additional side effects in children and adolescents (from 9 to and including 17 years of age: uncommon (may affect up to 1 user in 100): itchy rash (urticaria).

Reporting of side effects or any suspected adverse event: if the patient experiences any side effects after vaccination, advised to seek immediate medical attention.

By reporting side effects, it can help provide more information on the safety of the vaccine.

Click to view adr monitoring form

Interactions

Using other medicines and dengvaxia: dengvaxia may not have an optimal effect if it used at the same time as medicines that suppress the immune system such as corticosteroids or chemotherapy.

Inform the physician, pharmacist or nurse if the patient is taking or has recently taken any other vaccines or any other medicines, including medicines obtained without a prescription.

Caution for usage

Before administering any biological, the person responsible for administration must take all precautions to prevent allergic or other reactions. As with all injectable vaccines, appropriate medical treatment and supervision must always be readily available in the event of an anaphylactic reaction following the administration of dengvaxia.

Epinephrine (1: 1000) and other appropriate agents used to control immediate allergic reactions must be available to treat unexpected events such as anaphylaxis.

Dengvaxia must not be mixed with other medicinal products in the same syringe.

Dengvaxia must not be administered by intravascular injection under any circumstances.

Syncope (fainting) can occur following, or even before, any vaccination as a psychogenic response to injection with a needle. Procedures should be in place to prevent injury from falling and to manage syncopal reactions.

Separate syringes and needles, separate injection sites and preferably separate limbs must be used if any other vaccine (s) or medicinal product (s) is/are concomitantly administered.

Dengvaxia is reconstituted by transferring all the solvent (0.4% sodium chloride solution) provided in the blue-labeled pre-filled syringe into the vial of freeze dried powder with a yellowish green flip off cap. The pre-filled syringe is fitted with a sterile needle for this transfer. The vial is then gently swirled. After complete dissolution, a 0.5 ml dose of reconstituted suspension is withdrawn into the same syringe. For injection, the syringe should be fitted with the new sterile needle.

The suspension should be visually inspected prior to administration. After reconstitution, dengvaxia is clear, colorless liquid with the possible presence of white to translucent particles (of endogenous nature).

After reconstitution with the solvent provided, dengvaxia must be used immediately.

Any unused dengvaxia or waste material should be disposed of, preferably by heat inactivation or incineration, in accordance with local regulations.

Do not throw away any medicines via wastewater or household waste. Ask a pharmacist on how to throw away medicines that no longer use. These measures will help to protect the environment.

Storage

Store in a refrigerator. Do not freeze. Keep the vaccine in the outer carton in order to protect it from light.

Description

After reconstitution, one dose (0.5 ml) contains 4.5-6.0 log10 ccid50* of each serotype of the cyd dengue virus** (1, 2, 3 and 4).

* ccid50: 50% cell culture infectious dose.

** produced in serum-free vero cells by recombinant dna technology.

The powder is a white, homogenous, freeze-dried powder with possible retraction at the base, and may form a ring-shaped cake.

The solvent (0.4% sodium chloride solution) is a clear, colorless liquid.

After reconstitution with the solvent provided, dengvaxia is a clear, colorless liquid with the possible presence of white to translucent particles.

Excipients/inactive ingredients: essential amino acids including l-phenylalanine, non-essential amino acids, l-arginine hydrochloride, sucrose, d-trehalose dihydrate, d-sorbitol, trometamol, urea, sodium chloride, water for injections.

Mechanism of action

Dengvaxia contains dengue virus serotypes 1, 2, 3 and 4 that have been weakened. Dengvaxia works by stimulating the body's natural defenses (immune system), which produces its own protection (antibodies) against the viruses that cause dengue disease.

Dengue is a viral infection transmitted to humans through the bite of an infected aedes mosquito. Dengue is not transmitted directly from person-to-person. Nevertheless the virus which replicates in an infected individual can be transmitted to other humans through mosquito bites for 4-5 days (maximum 12 days) after the first symptoms appear.

Dengue disease results in a wide range of symptoms including fever, headache, pain behind the eyes, muscle and joint pain, nausea, vomiting, swollen glands or skin rash. Symptoms usually last for 2-7 days. Dengue disease can also be asymptomatic.

However, occasionally dengue can be severe and potentially lead to hospitalization and in rare cases to death. Severe dengue is characterized by high fever and any of the following symptoms: severe abdominal pain, persistent vomiting, rapid breathing, severe bleeding, bleeding in stomach, bleeding gums, fatigue, restlessness, coma, seizure and organ failure.

Source:- http://www.mims.com/philippines/drug/info/dengvaxia

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