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Dr. Sandesh J. Mehta

Dentist, Mumbai

Dr. Sandesh J. Mehta Dentist, Mumbai
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I'm a caring, skilled professional, dedicated to simplifying what is often a very complicated and confusing area of health care....more
I'm a caring, skilled professional, dedicated to simplifying what is often a very complicated and confusing area of health care.
More about Dr. Sandesh J. Mehta
Dr. Sandesh J. Mehta is one of the best Dentists in Mumbai, Mumbai. He is currently practising at Swastik Dental Clinic in Mumbai, Mumbai. Book an appointment online with Dr. Sandesh J. Mehta and consult privately on Lybrate.com.

Lybrate.com has a nexus of the most experienced Dentists in India. You will find Dentists with more than 29 years of experience on Lybrate.com. Find the best Dentists online in Mumbai. View the profile of medical specialists and their reviews from other patients to make an informed decision.

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Hindi
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Indian Dental Association
Dental Council of India

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Shop No- 10, Asha Housing Society, Krishna Nagar, Safepool, Sakinaka. Landmark: Near Sakinaka Metro Station, MumbaiMumbai Get Directions
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I am 27 years old male. Am facing a problem of bleeding in the tooth gum at the end of last teeth. Currently using red dabur toothpaste. Expecting your suggestions for this.

BDS
Dentist, Navi Mumbai
I am 27 years old male. Am facing a problem of bleeding in the tooth gum at the end of last teeth. Currently using re...
You're telling that you have bleeding gum in last corner tooth it suggests that your wisdom tooth must try to erupt and it get infected with your food lodgement in perticular area get proper pocket cleaning from consulting near by dentist.
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Dengue Vaxia

M.B.B.S,C.C.A,D.C.A,AASECT,FPA,AAD,M.I.M.S
General Physician,
Dengue Vaxia

Dengvaxia - first vaccine against dengue

Dengvaxia is a vaccine used to help protect adult or children against dengue disease caused by dengue virus serotypes 1, 2, 3 and 4. Dengvaxia is given to adults, adolescents and children 9 through 45 years of age living in endemic areas.

Read more:

Dengue symptoms and what to do if you think you have denguedengue fever - remedies using papaya leaf juice

Full prescribing info - dengvaxia

Contents

Dengue tetravalent vaccine (live, attenuated).

Indications / uses

Dengvaxia is a vaccine used to help protect adult or children against dengue disease caused by dengue virus serotypes 1, 2, 3 and 4. Dengvaxia is given to adults, adolescents and children 9 through 45 years of age living in endemic areas.

Dosage / direction for use

The patient will receive 3 injections of 0.5 ml each at 6-month intervals.

The first injection will occur at the chosen or scheduled date; the second injection, 6 months after the first injection; and the third injection, 6 months after the second injection. Dengvaxia should be used according to the local vaccination schedule.

If the patient forgot an injection of dengvaxia: if the patient missed a scheduled injection, the physician will decide when to give the missed injection.

It is important that the patient follows the instructions of the physician, pharmacist or nurse regarding return visits for the follow-up injection. If the patient forgets or is not able to go back to the physician, pharmacist or nurse at the scheduled time, ask the physician, pharmacist or nurse for advice.

Administration: dengvaxia is given by the physician or nurse as an injection underneath the skin (subcutaneous route) in the upper arm.

Contraindications

Do not use dengvaxia if the patient is allergic (hypertensive) to the active substances or any of the other ingredients of dengvaxia listed in description (see description); has developed an allergic reaction after prior administration of dengvaxia. Signs of an allergic reaction may include an itchy rash, shortness of breath and swelling of the face and tongue; is suffering from a disease with mild to high fever or acute disease. In this case, the physician will postpone the administration of dengvaxia until the patient has recovered; has a weakened immune system, for example due to a genetic defect, hiv infection or therapies that affect the immune system (for example, high-dose corticosteroids or chemotherapy); is pregnant; is breastfeeding.

Use in pregnancy lactation: dengvaxia must not be given to pregnant or breastfeeding women.

If the patient is of child-bearing stage, the patient should take the necessary precautions to avoid pregnancy for 1 month following administration of dengvaxia; is pregnant or breastfeeding, the patient thinks may be pregnant or is planning to have a baby, ask the physician, pharmacist or nurse for advice before receiving dengvaxia.

Special precautions

Inform the physician, pharmacist or nurse before receiving dengvaxia if the patient is taking an immunosuppressive treatment (prednisone or equivalent to 20 mg or 2 mg/kg for 2 weeks or more). The physician will postpone administration of dengvaxia until 4 weeks after the treatment is discontinued; has experienced any health problems after prior administration of any vaccines. The physician will carefully consider the risks and benefits of vaccination.

As with all vaccines, dengvaxia may not protect 100% of persons who have been vaccinated. Vaccination with dengvaxia is not a substitute for protection against mosquito bites. The patient should take appropriate precautions to prevent mosquito bites, including the use of repellents, adequate clothing, and mosquito nets.

Fainting, sometimes accompanied by falling, can occur (mostly in adolescents) following, or even before, any injection with a needle. Therefore inform the physician, pharmacist or nurse if the patient fainted with a prior injection.

Adults above 45 years of age: adults above 45 years of age should not receive the vaccine.

Driving and using machines: no data are available on the effects of dengvaxia on the ability to drive or use machines.

Use in children: children less than 9 years of age should not receive the vaccine.

Side effects

Like all medicines, dengvaxia can cause side effects, although not all patients get them.

Serious allergic reactions: if any of these symptoms occur after leaving the place where the patient received an injection, consult a physician immediately: difficulty in breathing, blueness of the tongue or lips, a rash, swelling of the face or throat, low blood pressure causing dizziness or collapse.

When these signs and symptoms occur they usually develop quickly after the injection is given and while the patient is still in clinic or physician's surgery.

Serious allergic reactions are very rare (may affect up to 1 in 10, 000 people), after receiving any vaccine.

Other side effects: the following side effects were reported during clinical studies in children, adolescents and adults (from 9 to and including 60 years of age). Most of the reported side effects occurred within 3 days after the injection of the vaccine: very common (may affect more than 1 user in 10): headache, muscle pain (myalgia), generally feeling unwell (malaise), feeling of weakness (asthenia), injection site pain, fever.

Common (may affect up to 1 user in 10): injection site reactions: redness (erythema), bruising (hematoma), swelling, and itching (pruritus).

Uncommon (may affect up to 1 user in 100): infections of the upper respiratory tract, dizziness, sore throat (oropharyngeal pain), cough, runny nose (rhinorrhea), nausea, skin eruption (rash), neck pain, hardening of skin at the injection site (injection site induration).

Additional side effects in adults (from 18 to and including 60 years of age): uncommon (may affect up to 1 user in 100): swollen glands (lymphadenopathy), migraine, joint pain (arthralgia), flu-like symptoms (influenza-like illness).

Additional side effects in children and adolescents (from 9 to and including 17 years of age: uncommon (may affect up to 1 user in 100): itchy rash (urticaria).

Reporting of side effects or any suspected adverse event: if the patient experiences any side effects after vaccination, advised to seek immediate medical attention.

By reporting side effects, it can help provide more information on the safety of the vaccine.

Click to view adr monitoring form

Interactions

Using other medicines and dengvaxia: dengvaxia may not have an optimal effect if it used at the same time as medicines that suppress the immune system such as corticosteroids or chemotherapy.

Inform the physician, pharmacist or nurse if the patient is taking or has recently taken any other vaccines or any other medicines, including medicines obtained without a prescription.

Caution for usage

Before administering any biological, the person responsible for administration must take all precautions to prevent allergic or other reactions. As with all injectable vaccines, appropriate medical treatment and supervision must always be readily available in the event of an anaphylactic reaction following the administration of dengvaxia.

Epinephrine (1: 1000) and other appropriate agents used to control immediate allergic reactions must be available to treat unexpected events such as anaphylaxis.

Dengvaxia must not be mixed with other medicinal products in the same syringe.

Dengvaxia must not be administered by intravascular injection under any circumstances.

Syncope (fainting) can occur following, or even before, any vaccination as a psychogenic response to injection with a needle. Procedures should be in place to prevent injury from falling and to manage syncopal reactions.

Separate syringes and needles, separate injection sites and preferably separate limbs must be used if any other vaccine (s) or medicinal product (s) is/are concomitantly administered.

Dengvaxia is reconstituted by transferring all the solvent (0.4% sodium chloride solution) provided in the blue-labeled pre-filled syringe into the vial of freeze dried powder with a yellowish green flip off cap. The pre-filled syringe is fitted with a sterile needle for this transfer. The vial is then gently swirled. After complete dissolution, a 0.5 ml dose of reconstituted suspension is withdrawn into the same syringe. For injection, the syringe should be fitted with the new sterile needle.

The suspension should be visually inspected prior to administration. After reconstitution, dengvaxia is clear, colorless liquid with the possible presence of white to translucent particles (of endogenous nature).

After reconstitution with the solvent provided, dengvaxia must be used immediately.

Any unused dengvaxia or waste material should be disposed of, preferably by heat inactivation or incineration, in accordance with local regulations.

Do not throw away any medicines via wastewater or household waste. Ask a pharmacist on how to throw away medicines that no longer use. These measures will help to protect the environment.

Storage

Store in a refrigerator. Do not freeze. Keep the vaccine in the outer carton in order to protect it from light.

Description

After reconstitution, one dose (0.5 ml) contains 4.5-6.0 log10 ccid50* of each serotype of the cyd dengue virus** (1, 2, 3 and 4).

* ccid50: 50% cell culture infectious dose.

** produced in serum-free vero cells by recombinant dna technology.

The powder is a white, homogenous, freeze-dried powder with possible retraction at the base, and may form a ring-shaped cake.

The solvent (0.4% sodium chloride solution) is a clear, colorless liquid.

After reconstitution with the solvent provided, dengvaxia is a clear, colorless liquid with the possible presence of white to translucent particles.

Excipients/inactive ingredients: essential amino acids including l-phenylalanine, non-essential amino acids, l-arginine hydrochloride, sucrose, d-trehalose dihydrate, d-sorbitol, trometamol, urea, sodium chloride, water for injections.

Mechanism of action

Dengvaxia contains dengue virus serotypes 1, 2, 3 and 4 that have been weakened. Dengvaxia works by stimulating the body's natural defenses (immune system), which produces its own protection (antibodies) against the viruses that cause dengue disease.

Dengue is a viral infection transmitted to humans through the bite of an infected aedes mosquito. Dengue is not transmitted directly from person-to-person. Nevertheless the virus which replicates in an infected individual can be transmitted to other humans through mosquito bites for 4-5 days (maximum 12 days) after the first symptoms appear.

Dengue disease results in a wide range of symptoms including fever, headache, pain behind the eyes, muscle and joint pain, nausea, vomiting, swollen glands or skin rash. Symptoms usually last for 2-7 days. Dengue disease can also be asymptomatic.

However, occasionally dengue can be severe and potentially lead to hospitalization and in rare cases to death. Severe dengue is characterized by high fever and any of the following symptoms: severe abdominal pain, persistent vomiting, rapid breathing, severe bleeding, bleeding in stomach, bleeding gums, fatigue, restlessness, coma, seizure and organ failure.

Source:- http://www.mims.com/philippines/drug/info/dengvaxia

More information about dengvaxia - first vaccine against dengue

Sanofi awaits govt approval to launch dengue vaccine in india

Sanofi pasteur - dengue vaccine frequently asked questions

13 people found this helpful

I have pain on the left side of the jaw. And I'm a chain smoker. What should I do?

MDS - Oral & Maxillofacial Surgery
Dentist, Chennai
We need more investigations (full mouth x-ray) & clinical examination to decide upon treatment. Dental tips: - visit a dentist every six months for cleaning and a thorough dental check-up. Limit sugary food to avoid tooth decay. Gargle your mouth thoroughly after every meal. Scrub gently to clean your tongue with a tongue cleaner. Floss all your teeth inter dentally & brush twice daily, morning & night, up & down short vertical strokes, with ultra-soft bristles, indicator brush. Tooth brush to be changed every 2 months.
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oral health

BDS
Dentist, Cuttack
oral health
Visit a dentist regularly for oral health checkups.
2 people found this helpful

My age is twenty I have teeth problem when I eat cold food my teeth is created so pain sensitive. please help what can I do?

DNB, MDS Endodontist, BDS
Dentist, Bangalore
My age is twenty I have teeth problem when I eat cold food my teeth is created so pain sensitive. please help what ca...
Cold sensitivity can be due to dental decay or abrasion of the teeth. You can use a desensitizing paste for temporary relief. Please consult a dentist and get it diagnosed and then proceed with the appropriate treatment.
1 person found this helpful
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BDS
Dentist, Thane
Activities like cracking nuts, removing bottle tops or ripping open packaging should not be performed by making use of our teeth. It can result in broken or chipped teeth. Our teeth should only be used for chewing food.
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I am sensing burning sensation on tongue. On seeing there are small red dots all over the tongue. What should I do?

MDS
Dentist, Sangli
I am sensing burning sensation on tongue. On seeing there are small red dots all over the tongue. What should I do?
It may be glossitis, which may be because of fever, low nutrition diet, lack of sleep, increase in stress, allergy to some type of food or spices, hormonal disturbance. Please correct the cause. Pain and discomfort to tongue with local application of anabel gel half hour before meals.
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I am 22 year old. I have wisdom teeth which is growing horizontally. I have lot of pain what will I do?

BDS
Dentist, Kolkata
Horizontally growing wisdom teeth may be removed out from your mouth surgically as there is no other option for it. So please see a nearby maxillofacial surgeon for it.
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My mom has burning sensation inside mouth in tongue also she feel difficulty in eating hot and little spicy food. Doctor give some vitamin b complex medicine n she has no allergy or any diseases from past this is first time happen and also color of lips turned little black. Plez suggest what to eat to give relief or to make it fine. She is 42 year.

BDS
Dentist, Gurgaon
My mom has burning sensation inside mouth in tongue also she feel difficulty in eating hot and little spicy food. Doc...
Kindly apply dologel ct over affected area. For three to five minutes. And then rinse your mouth after that. This should be done two to three times a day daily for a week. Hopefully the burning sensation will come down. 20 minutes prior to eating food.
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I got some red color spots on my tongue. Very painful and burning. I am unable to talk and eat. I think the reason for that is bubble gum. That is not suited for me. Please give me good medicines.

Bachelor of Ayurveda, Medicine and Surgery (BAMS)
Ayurveda, Bhopal
hello if it side effects of bubble gum then avoid it chew 2-3 leaves of guava early morning avoid oily spicy food further consult
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I am 25 year female, my upar teeth is come out more in mouth, and I am suffering in this, so How can I resolving my problem,

oral implantology, BDS
Dentist, Jaipur
I am 25 year female, my upar teeth is come out more in mouth, and I am suffering in this, so How can I resolving my p...
you need to go for orthodontic treatment or braces. ....go to a dentist for thorough check up and treatment plan
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I am 21 year old, I recently had severe tooth ache and dentist after x ray said, its bcz 1 of the wisdom teeth which is half grown outside gums and unable to come out completely as there's no space for it. He also said that I need to get all 4 teeth removed some day as there's no space and will cause much pain further. I was said its not immediately necessary to remove tooth but I can go for it when the pain gets worse. But surprisingly after few days the tooth ache has completely gone by itself and I have no other dental problem .what does this mean? Did my tooth grow normal? Do I need to take an x ray to confirm it inspite of no pain at all.

BDS, MDS, Post Graduate Diploma In Hospital Administration (PGDHA)
Dentist, Mumbai
I am 21 year old, I recently had severe tooth ache and dentist after x ray said, its bcz 1 of the wisdom teeth which ...
The wisdom tooth errors anytime after 18 years. If the xray that you have taken shows the tooth in an abnormal position (other than straight upright, please have the tooth extracted by the dentist. The previous episode of pain one reason could be that there must be food particles stick between tooth and gums. If the tooth position was not normal it is likely that it will never come up straight. Please take an Xray to confirm. You can also send me a picture of the xray to help you better.
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I suffer from receding gums after my first child birth. Within a span of four years after my pregnancy I have gone through one root canal and five fillings inspite of taking the best care for my teeth. Before my pregnancy, the first 26 years of my life I did not have a single cavity but now my teeth seem to spoil rapidly. Am worried.

BDS
Dentist, Madurai
I suffer from receding gums after my first child birth. Within a span of four years after my pregnancy I have gone th...
Hello lybrate-user, Do not worry. Hormonal variation during pregnancy would have lead to some changes in your gums and mouth. Do oil pulling using pure coconut oil regularly this will help you a lot. Follow a proper brushing technique. While brushing clean your tongue, area inside your cheeks. Don't forget to massage your gums.
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Hi The enamel of my teeth has become weak leading to chewing problem. Dentist advised vantage toothpaste, which has helped. What else can I do?

BDS
Dentist, Delhi
Hello, sir chewing problems can also be caused due to unhealthy gums around teeth, so get cleaning procedures done yearly and use gum paint massages to stregthen your gums. If needed restorations or crowns can be given where the enamel has chipped or broken.
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BDS
Dentist, Delhi
Always rinse your tooth brush thoroughly after brushing, and allow it to air-dry before using it again.
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I am 18 year old male and my teeth have too much gap. Not even this they are also outer side which makes me look feel odd. Please suggest what to do so that gap may decrease and outside also.

BDS
Dentist, Delhi
I am 18 year old male and my teeth have too much gap. Not even this they are also outer side which makes me look feel...
The process of filling the gap between teeth is known as orthodontic treatment, wherein you will be required to wear braces (an appliance with wires) for anywhere between 6 months to 1 year, depending upon the exact condition of your teeth. However, this treatment will serve as a permanent solution to your problem. You teeth alignment will become better and your smile will improve, These days, braces, similar to the color of teeth (ceramic braces) have also become available which are potentially much better looking than the conventional silver appliances. You can come over to my clinic in Delhi to know more about orthodontic treatment.
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My teeth are paining from many days. There are some kind of hole in the teeth with black surrounded.

BDS
Dentist, Ghaziabad
My teeth are paining from many days. There are some kind of hole in the teeth with black surrounded.
This is cavity problem. When the cavity reaches deep into the nerves then the feeling of pain is experienced. For temporary relief you can take painkillers but permanent solution is getting them filled. If the cavities r deep then rct is required.
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I am suffering with teeth pain since 1 month not even 1 medicine also working how my pain wil go can you help me.

BDS
Dentist, Vadodara
I am suffering with teeth pain since 1 month not even 1 medicine also working how my pain wil go can you help me.
Teeth pain are mostly because of tooth decay (cavities). Medicine can give you temporary relief. Permanent solution can be root canal treatment or removal of tooth depending on the cavity size n spread of infection.
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I am a 18 years old girl. I have yellow colur on my teeth. I brush 2 tyms in a day. But still no change.What should I do?

MDS - Oral & Maxillofacial Surgery
Dentist, Chennai
I am a 18 years old girl. I have yellow colur on my teeth. I brush 2 tyms in a day. But still no change.What should I...
Kindly consult a dentist in person for further suggestion. We need more investigations to decide upon treatment. You may need deep cleaning along with whitening (bleaching) procedures and / or artificial enamel filling. Advance procedures can be done with laser. You may consult me in person. Dental tips: - visit a dentist every six months. Gargle your mouth thoroughly after every meal. Scrub gently to clean your tongue with a tongue cleaner. Floss all your teeth inter dentally & brush twice daily, morning & night, up & down short vertical strokes, with ultra-soft bristles, indicator brush.
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