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Dr. Rahul Chavan

Dentist, Mumbai

Dr. Rahul Chavan Dentist, Mumbai
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I pride myself in attending local and statewide seminars to stay current with the latest techniques, and treatment planning....more
I pride myself in attending local and statewide seminars to stay current with the latest techniques, and treatment planning.
More about Dr. Rahul Chavan
Dr. Rahul Chavan is a renowned Dentist in Andheri West, Mumbai. You can meet Dr. Rahul Chavan personally at Status Dental Clinic in Andheri West, Mumbai. Save your time and book an appointment online with Dr. Rahul Chavan on Lybrate.com.

Find numerous Dentists in India from the comfort of your home on Lybrate.com. You will find Dentists with more than 37 years of experience on Lybrate.com. You can find Dentists online in Mumbai and from across India. View the profile of medical specialists and their reviews from other patients to make an informed decision.

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Clinic No 17, Blasian Apartments, Ceaser And S V Road Junction, Amboli, Andheri West. Landmark: Opposite Amboli Church, MumbaiMumbai Get Directions
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Dengue Vaxia

M.B.B.S,C.C.A,D.C.A,AASECT,FPA,AAD,M.I.M.S
General Physician,
Dengue Vaxia

Dengvaxia - first vaccine against dengue

Dengvaxia is a vaccine used to help protect adult or children against dengue disease caused by dengue virus serotypes 1, 2, 3 and 4. Dengvaxia is given to adults, adolescents and children 9 through 45 years of age living in endemic areas.

Read more:

Dengue symptoms and what to do if you think you have denguedengue fever - remedies using papaya leaf juice

Full prescribing info - dengvaxia

Contents

Dengue tetravalent vaccine (live, attenuated).

Indications / uses

Dengvaxia is a vaccine used to help protect adult or children against dengue disease caused by dengue virus serotypes 1, 2, 3 and 4. Dengvaxia is given to adults, adolescents and children 9 through 45 years of age living in endemic areas.

Dosage / direction for use

The patient will receive 3 injections of 0.5 ml each at 6-month intervals.

The first injection will occur at the chosen or scheduled date; the second injection, 6 months after the first injection; and the third injection, 6 months after the second injection. Dengvaxia should be used according to the local vaccination schedule.

If the patient forgot an injection of dengvaxia: if the patient missed a scheduled injection, the physician will decide when to give the missed injection.

It is important that the patient follows the instructions of the physician, pharmacist or nurse regarding return visits for the follow-up injection. If the patient forgets or is not able to go back to the physician, pharmacist or nurse at the scheduled time, ask the physician, pharmacist or nurse for advice.

Administration: dengvaxia is given by the physician or nurse as an injection underneath the skin (subcutaneous route) in the upper arm.

Contraindications

Do not use dengvaxia if the patient is allergic (hypertensive) to the active substances or any of the other ingredients of dengvaxia listed in description (see description); has developed an allergic reaction after prior administration of dengvaxia. Signs of an allergic reaction may include an itchy rash, shortness of breath and swelling of the face and tongue; is suffering from a disease with mild to high fever or acute disease. In this case, the physician will postpone the administration of dengvaxia until the patient has recovered; has a weakened immune system, for example due to a genetic defect, hiv infection or therapies that affect the immune system (for example, high-dose corticosteroids or chemotherapy); is pregnant; is breastfeeding.

Use in pregnancy lactation: dengvaxia must not be given to pregnant or breastfeeding women.

If the patient is of child-bearing stage, the patient should take the necessary precautions to avoid pregnancy for 1 month following administration of dengvaxia; is pregnant or breastfeeding, the patient thinks may be pregnant or is planning to have a baby, ask the physician, pharmacist or nurse for advice before receiving dengvaxia.

Special precautions

Inform the physician, pharmacist or nurse before receiving dengvaxia if the patient is taking an immunosuppressive treatment (prednisone or equivalent to 20 mg or 2 mg/kg for 2 weeks or more). The physician will postpone administration of dengvaxia until 4 weeks after the treatment is discontinued; has experienced any health problems after prior administration of any vaccines. The physician will carefully consider the risks and benefits of vaccination.

As with all vaccines, dengvaxia may not protect 100% of persons who have been vaccinated. Vaccination with dengvaxia is not a substitute for protection against mosquito bites. The patient should take appropriate precautions to prevent mosquito bites, including the use of repellents, adequate clothing, and mosquito nets.

Fainting, sometimes accompanied by falling, can occur (mostly in adolescents) following, or even before, any injection with a needle. Therefore inform the physician, pharmacist or nurse if the patient fainted with a prior injection.

Adults above 45 years of age: adults above 45 years of age should not receive the vaccine.

Driving and using machines: no data are available on the effects of dengvaxia on the ability to drive or use machines.

Use in children: children less than 9 years of age should not receive the vaccine.

Side effects

Like all medicines, dengvaxia can cause side effects, although not all patients get them.

Serious allergic reactions: if any of these symptoms occur after leaving the place where the patient received an injection, consult a physician immediately: difficulty in breathing, blueness of the tongue or lips, a rash, swelling of the face or throat, low blood pressure causing dizziness or collapse.

When these signs and symptoms occur they usually develop quickly after the injection is given and while the patient is still in clinic or physician's surgery.

Serious allergic reactions are very rare (may affect up to 1 in 10, 000 people), after receiving any vaccine.

Other side effects: the following side effects were reported during clinical studies in children, adolescents and adults (from 9 to and including 60 years of age). Most of the reported side effects occurred within 3 days after the injection of the vaccine: very common (may affect more than 1 user in 10): headache, muscle pain (myalgia), generally feeling unwell (malaise), feeling of weakness (asthenia), injection site pain, fever.

Common (may affect up to 1 user in 10): injection site reactions: redness (erythema), bruising (hematoma), swelling, and itching (pruritus).

Uncommon (may affect up to 1 user in 100): infections of the upper respiratory tract, dizziness, sore throat (oropharyngeal pain), cough, runny nose (rhinorrhea), nausea, skin eruption (rash), neck pain, hardening of skin at the injection site (injection site induration).

Additional side effects in adults (from 18 to and including 60 years of age): uncommon (may affect up to 1 user in 100): swollen glands (lymphadenopathy), migraine, joint pain (arthralgia), flu-like symptoms (influenza-like illness).

Additional side effects in children and adolescents (from 9 to and including 17 years of age: uncommon (may affect up to 1 user in 100): itchy rash (urticaria).

Reporting of side effects or any suspected adverse event: if the patient experiences any side effects after vaccination, advised to seek immediate medical attention.

By reporting side effects, it can help provide more information on the safety of the vaccine.

Click to view adr monitoring form

Interactions

Using other medicines and dengvaxia: dengvaxia may not have an optimal effect if it used at the same time as medicines that suppress the immune system such as corticosteroids or chemotherapy.

Inform the physician, pharmacist or nurse if the patient is taking or has recently taken any other vaccines or any other medicines, including medicines obtained without a prescription.

Caution for usage

Before administering any biological, the person responsible for administration must take all precautions to prevent allergic or other reactions. As with all injectable vaccines, appropriate medical treatment and supervision must always be readily available in the event of an anaphylactic reaction following the administration of dengvaxia.

Epinephrine (1: 1000) and other appropriate agents used to control immediate allergic reactions must be available to treat unexpected events such as anaphylaxis.

Dengvaxia must not be mixed with other medicinal products in the same syringe.

Dengvaxia must not be administered by intravascular injection under any circumstances.

Syncope (fainting) can occur following, or even before, any vaccination as a psychogenic response to injection with a needle. Procedures should be in place to prevent injury from falling and to manage syncopal reactions.

Separate syringes and needles, separate injection sites and preferably separate limbs must be used if any other vaccine (s) or medicinal product (s) is/are concomitantly administered.

Dengvaxia is reconstituted by transferring all the solvent (0.4% sodium chloride solution) provided in the blue-labeled pre-filled syringe into the vial of freeze dried powder with a yellowish green flip off cap. The pre-filled syringe is fitted with a sterile needle for this transfer. The vial is then gently swirled. After complete dissolution, a 0.5 ml dose of reconstituted suspension is withdrawn into the same syringe. For injection, the syringe should be fitted with the new sterile needle.

The suspension should be visually inspected prior to administration. After reconstitution, dengvaxia is clear, colorless liquid with the possible presence of white to translucent particles (of endogenous nature).

After reconstitution with the solvent provided, dengvaxia must be used immediately.

Any unused dengvaxia or waste material should be disposed of, preferably by heat inactivation or incineration, in accordance with local regulations.

Do not throw away any medicines via wastewater or household waste. Ask a pharmacist on how to throw away medicines that no longer use. These measures will help to protect the environment.

Storage

Store in a refrigerator. Do not freeze. Keep the vaccine in the outer carton in order to protect it from light.

Description

After reconstitution, one dose (0.5 ml) contains 4.5-6.0 log10 ccid50* of each serotype of the cyd dengue virus** (1, 2, 3 and 4).

* ccid50: 50% cell culture infectious dose.

** produced in serum-free vero cells by recombinant dna technology.

The powder is a white, homogenous, freeze-dried powder with possible retraction at the base, and may form a ring-shaped cake.

The solvent (0.4% sodium chloride solution) is a clear, colorless liquid.

After reconstitution with the solvent provided, dengvaxia is a clear, colorless liquid with the possible presence of white to translucent particles.

Excipients/inactive ingredients: essential amino acids including l-phenylalanine, non-essential amino acids, l-arginine hydrochloride, sucrose, d-trehalose dihydrate, d-sorbitol, trometamol, urea, sodium chloride, water for injections.

Mechanism of action

Dengvaxia contains dengue virus serotypes 1, 2, 3 and 4 that have been weakened. Dengvaxia works by stimulating the body's natural defenses (immune system), which produces its own protection (antibodies) against the viruses that cause dengue disease.

Dengue is a viral infection transmitted to humans through the bite of an infected aedes mosquito. Dengue is not transmitted directly from person-to-person. Nevertheless the virus which replicates in an infected individual can be transmitted to other humans through mosquito bites for 4-5 days (maximum 12 days) after the first symptoms appear.

Dengue disease results in a wide range of symptoms including fever, headache, pain behind the eyes, muscle and joint pain, nausea, vomiting, swollen glands or skin rash. Symptoms usually last for 2-7 days. Dengue disease can also be asymptomatic.

However, occasionally dengue can be severe and potentially lead to hospitalization and in rare cases to death. Severe dengue is characterized by high fever and any of the following symptoms: severe abdominal pain, persistent vomiting, rapid breathing, severe bleeding, bleeding in stomach, bleeding gums, fatigue, restlessness, coma, seizure and organ failure.

Source:- http://www.mims.com/philippines/drug/info/dengvaxia

More information about dengvaxia - first vaccine against dengue

Sanofi awaits govt approval to launch dengue vaccine in india

Sanofi pasteur - dengue vaccine frequently asked questions

13 people found this helpful

Dentist, Ahmedabad
Brush twice daily.

Special emphasis should be on before going to bed brushing.

flossing is also an important part of oral hygiene.

rk.
You found this helpful

MDS Endodontist, BDS
Dentist, Delhi
Our teeth should only be used for chewing purposes. Using them for performing other activities such as cracking nuts, removing bottle tops or ripping open packaging can cause chipped or broken teeth.
You found this helpful

I had injure on inner side of my lip from past 4 days what should I do to reduce it.

DNB, MDS Endodontist, BDS
Dentist, Bangalore
If it is an injury due to a fall, lip biting, or a sharp object, apply an anesthetic/antiseptic oral gel over the injury, avoid very spicy and hot food. It will slowly heal.
1 person found this helpful
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BDS
Dentist, Ahmedabad
Teeth are as precious as real pearls.
Get your teeth as attractive as your personality
by visiting dentist regularly.
2 people found this helpful

Hi Sir, I am 24 years old, actually I feel down from steps from 8 years back because of that my front tooth has been cracked and it turns to yellow colour, and I wish to get remove both (two) my front tooths and wish to attach or implement. Kindly provide me suggestions, what have to do?

BDS
Dentist, Mumbai
Hi Sir,
I am 24 years old, actually I feel down from steps from 8 years back  because of that my front 
tooth has bee...
Kindly visit dental surgeon. There is no need to remove the tooth, the teeth can be treated and a crown preparation can be done. You will have a beautiful smile after treatment.
3 people found this helpful
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Facing blisters in mouth in 2-3 days and also redness in mouth.What should i do?

Diploma In Dermatology And Venerology And Leprosy (DDVL), MBBS
Dermatologist,
Mouth ulcer (apthus ulcer) is mainly due to bad chemicals which are not cleared through our digestive system. By stool due to constipation, or other digestive problem, due to vitamins deficiency also. Or maybe by some infection, cancer also causes mouth ulcers. If you want advice please consult.
1 person found this helpful
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I do flossing and mouthwash daily once and brushing twice. Please let me know if this figure is enough for my teeth to last longer without any problem and what time is best to do flossing and mouthwash if I do them only once daily. Thank you.

BDS
Dentist, Jaipur
I do flossing and mouthwash daily once and brushing twice. Please let me know if this figure is enough for my teeth t...
Hello, Yes this is enough for you to brush twice daily and to use mouthwash also. Flossing is not for regular purposes. You have to limit that and use floss only when there is a food particle in between teeth. Use alcohol free mouthwash after brushing is enough to maintain a good oral health. Also sometimes it is needed to get your teeth cleaned by dentist for complete hygiene of mouth because they can reach at the part of teeth where you can't see. In every year or every 6 months it is recommended for everyone. Regards
1 person found this helpful
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When I drink cold water and eat the ice cream then start the pain in my teeth. Why start the pain in my teeth and gum?

BDS, CDE Endo-Prostho, CDE - Cast Partial & Complete Dentures
Dentist, Pune
When I drink cold water and eat the ice cream then start the pain in my teeth. Why start the pain in my teeth and gum?
Hello, pain could be because of 1.cavity 2. Infection to the roots of tooth. Consult a dentist, if there is a cavity get it filled and if there is any infection to roots get it treated.
9 people found this helpful
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I wanted a help regarding milky teeth not fall after grown up also. Is there is any help on this.

MDS - Oral & Maxillofacial Surgery
Dentist, Chennai
I wanted a help regarding milky teeth not fall after grown up also. Is there is any help on this.
We need more investigations (model study, full mouth & profile x-ray) & clinical examination to decide upon treatment. You may need fixed / removable braces. Requirements may depends on the age, complaint, duration of the treatment & affordability. Cost of cosmetic dentistry (braces) varies with dentist. Dental tips: - visit a dentist every six months for cleaning and a thorough dental check-up. Limit sugary food to avoid tooth decay. Gargle your mouth thoroughly after every meal. Scrub gently to clean your tongue with a tongue cleaner. Floss all your teeth inter dentally & brush twice daily, morning & night, up & down short vertical strokes, with ultra-soft bristles, indicator brush. Tooth brush to be changed every 2 months.
23 people found this helpful
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I have mouth problem in my teeth.

I have mouth problem in my teeth.
You are probably having problem in teeth in your mouth please visit a dental surgeon and get the teeth examined and he will do the needful required and treat the problem.
2 people found this helpful
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Having yellow teeth what should I do to make them white?

BDS
Dentist,
Having yellow teeth what should I do to make them white?
here is home remedy for brighter teeth--- Mix several teaspoons of baking soda with enough fresh lemon juice (or water) to make a paste. Wipe your teeth and any extra saliva off of them with a paper towel. Put a good amount of paste onto your toothbrush and apply. Leave the paste on for 1 minute, then rinse, so as to avoid the acid effecting enamel. If you are using just water you can leave it on for up to 3 minutes. for faster result you can go for TEETH BLEACHING from dentist...
1 person found this helpful
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Continuous bleeding is happening from my teeth since last week. What should I do?

MDS - Oral & Maxillofacial Surgery
Dentist, Chennai
Continuous bleeding is happening from my teeth since last week. What should I do?
Kindly consult a dentist in person for further suggestion. We need more investigations to decide upon treatment. You may need deep cleaning along with surgical, gum strengthening procedures. You may consult me in person too. Dental tips: - visit a dentist every six months. Gargle your mouth thoroughly after every meal. Scrub gently to clean your tongue with a tongue cleaner. Floss all your teeth inter dentally & brush twice daily, morning & night, up & down short vertical strokes, with ultra-soft bristles, indicator brush.
You found this helpful
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I am 16 year old male, my mouth smell foul whenever I take breath. What should I do?

BDS
Dentist, Bangalore
I am 16 year old male, my mouth smell foul whenever I take breath. What should I do?
Bad breath can be reduced or prevented if you: practice good oral hygiene. Brush twice a day with fluoride toothpaste to remove food debris and plaque. Don't forget to brush the tongue, too. Replace your toothbrush every 2 to 3 months or after an illness. Use floss or an interdental cleaner to remove food particles and plaque between teeth once a day. See your dentist regularly -- at least twice a year. He or she will conduct an oral exam and professional teeth cleaning and will be able to detect and treat periodontal disease, dry mouth, or other problems that may be the cause of bad mouth odor. Drink lots of water. This will keep your mouth moist. Chewing gum (preferably sugarless) stimulates the production of saliva, which helps wash away food particles and bacteria.
You found this helpful
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I'm chewing food's from one side I can't chew from another side what should I do for that?

BDS
Dentist, Delhi
I'm chewing food's from one side I can't chew from another side what should I do for that?
Hi, reason fr not able to chew can be becuse ofdecay on that side or gum inflammtion, you need to go to a dentist ti knw th reasn and than only treatmnt can be suggested fr nw an antibiotic andpainkiller fr 3days is advisble.
2 people found this helpful
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Take care of your teeth

BDS
Dentist, Gurgaon
Brush twice a day
Eat healthier food
No self medication
Avoid tobacco and smoking
Floss before bed time.
111 people found this helpful

I have constipation problem and bcz of that I m suffering from mouth ulcer so kindly give me solutions of this thing.

BHMS
Homeopath, Delhi
I have constipation problem and bcz of that I m suffering from mouth ulcer so kindly give me solutions of this thing.
Hello, you can take homoeopathic medicine Nux Vom 30 ( 4 drops in little water) thrice a day for a week and update. Drink lot of water Include fruits, raw vegetables and fresh vegetable juices in your diet.
6 people found this helpful
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I am 22 yr old girl am suffering from bad breath problem from so many years I have had a visit to dentist also but didn't get solved Please give me the solution.

Advanced Aesthetics, BDS
Dentist, Mumbai
Hi, there are various reasons of bad breath, like impurities in blood, inefficient digestive system, dry mouth (lack of saliva production), gum disease, cavities, plaque and tartar formation around teeth and gums, kind of diet, improper brushing / cleaning of mouth etc. I would advise you to get a thorough physical and dental examination to rule out the cause of bad breath and to solve it permanently. You can come for a consultation (free of cost) in our clinic.
1 person found this helpful
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Toothache suggest me some medicine

First of all for toothache you can have a pain killer like combiflam once tab in case of pain. But it is suggested that you get proper check up done by a dental surgeon and find out the cause of pain and get it treated properly.
2 people found this helpful
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She is 56 yes old. Suffering from pain in complete upper and lower jaws and fore head region. On examination dentist told tenderness in relation to upper right and left second premolars and lower left second molar, but there is no caries. And there is no findings in x- ray. No calculus only little debris present. What could be the region.

MDS - Oral & Maxillofacial Surgery
Dentist, Chennai
She is 56 yes old. Suffering from pain in complete upper and lower jaws and fore head region. On examination dentist ...
You may need root canal treatment. This procedure involves removing the infected pulp and then inserting a special type of filling to seal the tooth and prevent re-infection.
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