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Dr. Prince John

Oncologist, Mumbai

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Dr. Prince John Oncologist, Mumbai
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To provide my patients with the highest quality healthcare, I'm dedicated to the newest advancements and keep up-to-date with the latest health care technologies....more
To provide my patients with the highest quality healthcare, I'm dedicated to the newest advancements and keep up-to-date with the latest health care technologies.
More about Dr. Prince John
Dr. Prince John is a popular Oncologist in Sion, Mumbai. He is currently practising at Asian Institute of Oncology in Sion, Mumbai. Save your time and book an appointment online with Dr. Prince John on Lybrate.com.

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Asian Institute of Oncology

Asian Institute of Oncology, Ground Floor, K. J. Somaiya Hospital Campus, Off Eastern Express Highway, Sion(East), Mumbai - 400 022, MumbaiMumbai Get Directions
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Klatskin Tumour - Understanding It In Detail!

MD, MBBS
Oncologist, Ernakulam
Klatskin Tumour - Understanding It In Detail!

A fifty-four years old Marwari patient from Assam presented with progressive jaundice and intermittent episodes of abdominal pain for three months. CT scan of abdomen showed a small (1.5 x 1.5 cm) mass in the bifurcation of common bile duct which is causing biliary tract obstruction and hence jaundice. Portal nodes were not enlarged and there was no lesion in the liver parenchyma. At presentation, serum bilirubin level was high (14.7 mg/dl). Endoscopic biopsy and brushing cytology was adenocarcinoma and clinic-radiological diagnosis was ‘Klatskin tumour’. 

  • Metallic stenting was done to relieve jaundice and after stenting serum bilirubin level came down rapidly. PET scan showed increased uptake in the biliary duct region mass without any sign of metastasis. He was evaluated and planned for treatment with robotic radiosurgery. He was treated using robotic radiosurgery (CyberKnife) with high precision radiotherapy technique after fiducial placement (gold seeds) near the tumour. After one year, the patient had no obvious complain, liver function (no jaundice) was normal and CT scan evaluation showed completed resolution of the mass.  
  • Klatskin tumour is an uncommon tumour that arises from the bifurcation of common bile duct in the abdomen (duct that drains bile from liver). Patients usually present with progressive (increasing) persistent jaundice followed by pain in the upper abdomen. Surgical excision is the mainstay of treatment. However, surgery is not possible in majority of the patients owing to the location of the tumour, high jaundice and medical condition. Chemotherapy may not be an optimal option in majority of the patients as they present with high jaundice. Majority of such patients with poor medical condition are treated with only supportive care and prognosis is dismal (survival for a few months only).
  • Patients with metallic stent have relief from jaundice but unfortunately in a few weeks time, the stent gets blocked with tumour growth. Patients again present with high jaundice and have severely impaired quality of life. They complain of severe itching of entire body, loss of appetite and succumb due to impaired liver function from high jaundice/obstruction. The treatment is to have a longer ‘jaundice-free period’ which in turn improves quality of life and possibly survival function as well.  
  • Stereotactic body radiation therapy’s high dose radiation ‘sterilizes’ the metallic stent and bile duct region. It is assumed that with radiation therapy, blockage of bile duct and stent is delayed and patients have longer jaundice-free period.In Klatskin tumour, CyberKnife allows to deliver high dose of radiation in a short duration to the target without significant morbidity. If you wish to discuss about any specific problem, you can consult an Oncologist.
3107 people found this helpful

I am 22 year old girl m a virgin. Is it normal not to have nipples that do not stick out? My nipple come out only when I feel cold.

MS-General Surgery, MBBS
General Surgeon, Hyderabad
If nipples are deeply buried in the breast then it is a problem. If they are flat but can be pulled out or comes out on massage then it is normal.
1 person found this helpful
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What are the causes of skin cancer and what are the syndrome of it also tell me it's preventive measures.

MBBS
General Physician, Mumbai
What are the causes of skin cancer and what are the syndrome of it also tell me it's preventive measures.
If there is irritation over the skin for more than ten years than it can lead to cancer and for preventing it few diet tips - not to eat fried food items and can eat all green vegetables, moong, chana, dal, rice etc and to apply ghee over chappati and don't apply oil over chappati and to drink milk mixed with turmeric powder twice a day and if possible eat eggs on alternate days and if possible in breakfast eat atleast one bajra ka rotla and eat seasonal fruit.
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My dad is suffering from GI junction cancer with liver Mets from Feb 2016. Had 3 cycle of chemotherapy where his numbers and size of tumours reduced by 30 percent. Then after 2 more cycles it reduced by more 50 percent. Then in the month of December it increased by 33 percent. Again dctr advised for chemo. After 3 cycles it reduced slightly but pleural effusion and ascites are seen. Again after 3 cycle secondary cancer increased. Pleural effusion increased. Ascites increased. My question how after chemo cancer is increasing? What are the chances of survival here.

MS, DNB (Surgical Oncology)
Oncologist, Jodhpur
HI lybrate-user, As per your history disease of GI Junction with Liver metastasis, I Presume you want to say about GE junction, Post 2 lines of Chemotherapy and progressive. The overall picture is not happy, it will be advisable to meet the surgical Oncologist if I assume the ascites and pleural effusion is not disease related. If Ascites and Pleural effusion are disease related, which is more a possibility as per case scenario, there are limited options. One vital option would be targeted therapy, with Herceptin if not already instituted in case of Her 2 +ve cancer. Overall with limited information, I feel the picture is quite gloomy. Having said that, ultimate power is GOD, so don't lose hope and Keep fighting. Good luck.
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Is nipple discharge 7 days beforehand of menstrual beginning normal?or a sign of breast cancer?i m also having a lump like feeling in one of the breast.I m very afraid please help.

MD - Oncology
Oncologist, Hubli-Dharwad
Nipple discgharge periodically with menstruation may not be a cancer it may be fibroadenoma, but do a mamograpy to be sure and if require FNAC of the lump instead of sitting at home and getting worried, there are treatments available for cancers
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Sir, I have little reddish bumps on my palate. Is it because of smoking or oral cancer?

MCH - Surgical Oncology
Oncologist, Hubli-Dharwad
No dear. You hav to quit smoking. Please maintain oral hygiene with good mouth wash and b complex capsules once daily. Contact after observation of 15 days.
1 person found this helpful
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She is feeling pain in her nipples by touching from last 2-months. Also we marry each other 3-months back. Can you please suggest some treatment.

MBBS, MD - Medicine, MD - Oncology
Oncologist, Delhi
It is hormonal change. Do not press nipples aggressively. Slowly the pain will disappear of its own.
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I am having acute acidity problem from last few months. Is it a symptom of any abdominal cancer? Please answer. I am really worried about that.

MBBS
General Physician, Bangalore
I am having acute acidity problem from last few months. Is it a symptom of any abdominal cancer? Please answer. I am ...
No its not any cancer. Is just that you should have your meals on time everyday and do not skip any meals. If your feeling any mass per abdomen you can get an usg. But not required.
2 people found this helpful
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She's have a throat cancer. What we can give her in liquid form to eat and what precautions we can take for cure.

DNB, MBBS
Oncologist, Faridabad
Dear mam, throat cancer patients have difficulty in swallowing, so they can take lots of liquids and semisolids, rich in proteins, vitamins and minerals. She can take vegetable soups, buttermilk, milk, oats, porridge, fruits, juices etc for fast healing and recovery.
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Cervical Cancer

MBBS, DGO, DNB (Obstetrics and Gynecology), FMAS, FAM
Gynaecologist, Delhi
Play video

Symptoms, causes and treatment for Cervical Cancer

Namashkar. Hello, I’m Dr. Shalini Tiwari. I’m a gynaecologist practicing at East Delhi Surya Hospital. Aaj main apko cervical cancer ke bare mein kuch batana chahti hoon.

Today in India, there are so many women who are dying due to cervical cancer. It is one of the most common cancers in the world due to which women are affected. Why today I’m talking about cervical cancers? Today, sexual relations are on rise. Even young women like 16, 17, 18 year old are going for sexual relationship. I’m not saying that sexual relationship is wrong, but why I am talking about cervical cancer is because sexual relationships are one of the highest factors of cervical cancers. So let’s understand what actually cervical cancer is. To understand this, we need to know what cervix is. So I’d like to tell you that we have a uterus where our baby is grown and then born afterwards.

See, this is the uterus, and this is the cervix. So just as we have our face, as we have our lips, so our uterus has lips which is known as cervix. It is this portion which is affected most. Why? Because during sexual intercourse, due to repeated infections, and anything which is outside and which is externally entering into the vagina, first it will infect or affect this part of the uterus. This is known as cervix. So any infection, any erosion, any bleeding, any white discharge, anything which is affecting the cervix can give rise to cervical cancer. This is a very broad statement, there are definite…there are definitely some definite reasons, definite viruses which give rise to this cancer.

Coming on to symptoms of cervical cancer. So many of us have irregular menstrual bleeding, but we tend to ignore it. We should not. Abnormal menstrual bleeding is one of the finest and one of the earliest symptom of cervical cancer. So please don’t ignore it and visit your gynaecologist. Now you would like to know what abnormal bleeding is? So abnormal bleeding would be bleeding after intercourse, abnormal bleeding would be bleeding in between menstrual cycles, abnormal bleeding can be excessive bleeding during regular cycles. So any three of them, if it is there, you please visit your doctor, and get yourself checked.

Why so much of a hush-hush over cervical cancer all over the world? Because, number 1, it is common, number 2, it is a preventable cancer. It is a very slow growing cancer. It starts from the cervix, and then gradually gradually gradually it involves all of the uterus. But this gradual is so much that if we diagnose it, it can be actually cured 100%. That’s why we really need to be careful. You should be having a regular checkups, all women, specially all sexually active women. You should have regular checkups.

So what are the preventive checkups for cervical cancer?

  •  Pap test. All of us know Pap test. It is being advertised in TV, it is being advertised by WHO off and on. So every sexually active woman should get a Pap test every three years.
  • Similarly there is a virus called HPV virus, i.e, Human papillomavirus. This virus is a sexually transmitted virus. And if this virus is there, there are high chances that patient will develop cervical cancer. Though once infected with this virus, it doesn’t mean that it will be there throughout your life. Because it titles goes down in one year or two years, but then there are two specific types, like 16 type and 18 type of HPV virus, which can really give your body a potentiality to grow into cervical cancer. So you should get your HPV testing also done.
  • Third is colposcopy. Colposcopy is a screening test, and through colposcopy we see the cells of cervix directly under acetic acid, which really helps us to diagnose if the cells can grow into cancers, or these cells are benign cells. And these three tests are absolutely noninvasive tests, non-painful tests, and just OPD procedure for two to three or five minutes maximum. So you should…all of you should get these tests dine regularly. Number three, supposing we do these tests, and we diagnose that element of cancer is there. So if it is in initial stages, like we call it carcinoma, you won’t believe, to treat this we don’t even need to do hysterectomy. This is just we need to do a cryo, ye ek prakar ki thandi si  jo layman ki bhasha mein bolte hain, or use puri tarah ye erosion theek ho jata hain. Uske baad use jo cervical cells hote hain cancer waale, wo bhi mar jaate hain. And the chances of progressing into a frank carcinoma becomes almost negligible.

That’s why cervical cancer is everywhere. So we need to be very careful, we need to be very vigilant. Our health is in our hands. So if we are not vigilant about our health, no one else is going to tell us, please go to the doctor. Humein pata hona chahiye ki hamare mein infection ho raha hain, white discharge humein zyaada ho raha hain, bleeding humein zyaada ho rahi hain, so ;et’s viosit the doctor.

In the end, agar apko dikhana hain, aap chahte hain ki aap cervical cancer se bachein rahein, please come to me. I sit as Surya Hospital in East Delhi, or you can contact me through Lybrate. Thank you.

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