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Kidney Stones Treatment
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I've observed a blood stain on the toilet paper when I wiped my anus after using the toilet. I also felt a lump near the Anus part. It doesn't pain at all. I do feels itchy at times. Please help.
I have a dark blood clotted like spot inside the white portion of my eye since some years. Can I remove it?
Christmas & new year offers - skin whitening treatment
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Skin whitening is the practice of using substances, mixtures, or physical treatments to lighten skin color. Skin whitening treatments work by reducing the content of melanin of the skin. Many agents have been shown to be effective in skin whitening.
Specific zones of abnormally high pigmentation such as lentigo spots, moles and birthmarks may be de-pigmented to match to the surrounding skin. In cases of vitiligo, unaffected skin may be lightened to achieve a more uniform appearance.
Discovery and design
Melanogenesis inhibitors have been discovered and developed through several methods, including: screening of synthetic chemical libraries (high-throughput screening is occasionally used), screening of plant extracts, computational (in silico) search, found as a side effect of previously known drugs and exploration of structural analogues of previously known tyrosinase inhibitors based on knowledge (in varying degrees) of their structure-activity relationship. Thus, the development and discovery of melanogenesis inhibitors illustrates many of the methods used in drug design. Some of the most potent competitive reversible tyrosinase inhibitors are synthetic compounds with a potency hundreds of times that of kojic acid.
Mechanisms of action
Melanin is the main substance responsible for the color of the skin. Melanin is class of dark polymers generated by the body through the process of melanogenesis. Among the melanin pigmenting the skin and hair, 2 types can be distinguished based on its chemical composition and biological route of synthesis: the black/brown eumelanin and the red/yellow pheomelanin. The variation of skin color among individuals is mostly because of variation of the content of melanin in the skin. Skin with little or no melanin is almost white. Other factors influence skin color in a lesser degree, including the amount of blood in blood vessels (because of the color of blood), skin thickness and content of carotenoids in skin.
Melanin in synthesized in melanosomes which are organelles produced in melanocytes. Melanocytes are cells dedicated to this function that are present in the skin, hair follicles, and other structures of the body. The synthesis of melanin (also called" melanogenesis" and" melanization") involves a chain of enzyme-catalyzed chemical reactions and non-enzyme-catalyzed reactions. The main precursor to melanin is l-tyrosine. The first step of melanogenesis is the conversion of l-tyrosine to l-dopa; this is the first and rate-limiting step and is catalized by the enzyme tyrosinase. Other enzymes involved in the synthesis include tyrosinase-related protein 1 (trp1) and tyrosinase-related protein 2 (trp2); trp2 is also known as" dopachorome tautomerase" (dct). L-tyrosine is taken by the melanocytes from the intercellular medium, then transported to the melanosomes. L-tyrosine is also synthesized within the melanocytes from l-phenylalanine by the enzyme phenylalanine-hydroxylas (pah)
Melanosomes are transferred to keratinocytes (the most abundant cell type in the skin). Most of the melanin of skin is found in keratinocytes. Additionally, melanocytes interact with keratinocytes through chemical signaling.
Hi, I am a 22 year old male. I have a problem with the dark brown color of my skin. Pls suggest me something for a fair look.
I am a 18 year old boy, how to avoid black spots on my face can you please advise if there is any cream or what to do to clear black spots and pimples.
Previously I had pimples after using a cream. Now that I have got dark marks. How do I get clear scar free skin?
Hello, I am Dr Simal Soin. I ran a clinic called Ayna. Ayna means mirror. So, everything that makes you look and feel good here at Ayna is under one roof. What we offer you is a combination of various treatments which are done through cosmetic dermatology. We basically treat acne, acne scars, freckles, rosacea, open pores and address your skin texture issues. Through various modalities like hydra facials, lasers, peels and combined medical treatments with those as well. Then we have a hair clinic where we address Hair loss concerns through P.R. P. and treatments. We have an anti-ageing clinic where we specialize in treatments for your sagging skin, for double chin, for volume loss, for lines, wrinkles and just give you a very natural, rested, fresh look done through a combination of botox, fillers, thermage.
Then another thing that we do that nobody in India does is a foot clinic. We have a foot clinic where we do various pediatric treatments to treat your corns, warts and dead skin.
So, we also have a weight management and body contouring clinic where we are able to offer you treatments through a combination of technology and lifestyle management to address your weight loss concerns, to give you weight loss and help you maintain that for a long period of time.
So, if you want to take care of your skin on a regular basis some of them must use for your skin please use sunscreen every single day. One of the commonest cause of ageing of the skin is lack of sunscreen use, sun exposure which is unprotected. So, importantly, for sunscreen in the morning, use an antioxidant to basically combat all the free radical damage that your skin goes through every day with the pollution and the environment. Use a vitamin C serum or cream on your skin every day. Use a moisturizer on your skin every night and make sure you cleanse your skin regularly with good Micellar water. So these are the very basic things that everybody must do to keep their skin looking young. Visit your dermatologist every few months to get some new updates on what latest in the world of skin care and what is the good creams you can use to keep your skin looking good.
Treat any concern you have by visiting your dermatologist. Avoid using over the counter products. Our specialty is that we have a lot of doctors and nutritionists on site and all of our treatments are not only safe but they are also very effective at the same time so there are U.S.F.D approved and we have treated patients from all over the globe and people come regularly and repeatedly to have treatment with us from India and overseas.
If you have any medical or aesthetic or cosmetic queries about anything, please visit us on lybrate so we can sort out any issues that you might be having with your skin.