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Addison’s disease is considered to be a life threatening and serious illness. When one suffers from this disease, the amount of hormones like Aldosterone and Cortisol reduces rapidly due to the poor functioning of the Adrenal glands. The hormones that the Adrenal glands produce are necessary for the body to function normally. To better understand what Addison’s disease is all about, below are some basic facts.
- Fact 1: Addison’s disease is often confused or linked with adrenal insufficiency. However, Addison’s disease is more of an autoimmune disorder that later leads to adrenal insufficiency, which is a hormone-related imbalance.
- Fact 2: Addison’s disease can happen to anyone regardless of their gender or age. However, genetics may also have a role to play here, as those who have someone affected with Addison’s in the family, face greater risks.
- Fact 3: While for someone it may take years for totally disrupting the hormone production, for some it may grow worse very quickly. Though it is rare, it is possible.
- Fact 4: The symptoms of Addison’s disease often get unnoticed or misinterpreted, as the disease is very uncommon. This is a rare disease that occurs in one in a million.
- Fact 5: When suspected of having Addison’s disease, the screening process doesn’t take much time. Generally, a normal blood test showing the amounts of ACTH and cortisol hormone will confirm the diagnosis.
- Fact 6: Some very common symptoms of this disease are mild to severe pain in the bones and in the abdomen, weight loss, nausea, forgetfulness, low blood pressure and lack of energy. It is these common symptoms that can point to numerous other conditions that make its diagnosis a tricky one.
- Fact-7: Sometimes, Addison's disease may cause the skin tone to become darker due to the hormonal changes. It is probably the only disease that can cause such darkening or skin discolorations of the otherwise normal skin.
- Fact 8: People who have Addison’s disease generally become dependent on the daily intake of cortisol medications or steroids. Without Cortisol, the stress hormone, the body may go into serious adrenal crisis.
- Fact 9: When overlooked for a long time or not provided with the treatment and medication when needed, Addison's disease may lead to sudden organ failure. Therefore, understanding the symptoms and opting for a blood test is essential if this disease is suspected.
- Fact 10: Lastly, Addison's disease can be easily cured and treated by introducing a few serious lifestyle changes and hormonal therapies. Sometimes when oral hormone supplements fail to get properly absorbed, injecting the supplements becomes necessary.
Studies have shown that around 140 people approximately suffers from Addison's disease out of every million. Therefore, knowing the above-mentioned facts becomes necessary for have a clear understanding of the disease which may help in dealing with it in the best way possible. If you wish to discuss about any specific problem, you can consult an Endocrinologist.
I am diabetic for last 15 years. On galvusmet50/500 twice with amaryl2 once daily. For pressure olmax20 that gives my pressure at 166/66 .thyroxine 82. And other vitamins like becadexamine, dexorange,gemitrol, and cariprill as I have low rbc, wbc,and platelet count diagnosed as possible mds. Is it safe to take cardace2. 5.as previously I had taken then it was changed by doc. To nebicard and also given olmetAM40. Pressure was 140/60.55.
Adrenal cancer is a rare and aggressive disease that causes abnormal cell growth inside the adrenal cortex. This cancer usually appears as tumors at the outermost layer of the adrenal glands and gradually develops cancerous cells. In the majority of the cases, adrenal cancer is diagnosed only after it has been growing for several years.
While most of the adrenal cancer patients have the common symptoms, often some people feel just fine, unless until their doctors find the presence of cancerous cells in the adrenal cortex through CT scan. Generally, the symptoms of this life-threatening disease depend on three factors, which are:
- The particular type of overproduced hormone
- The tumor producing hormones excessively
- And, type of the tumor
However, it is the overproduction of particular hormones, that makes the majority of the symptoms visible. Below are the common symptoms of adrenal cancer, depending on hormone types that are overproduced during the presence of this disease.
Symptoms of cortisol overproduction
When the presence of adrenal cancer leads to excess production of the cortisol hormone, people start experiencing different types of symptoms. The accumulation of fat behind the shoulders and neck, gradual weight gain in the stomach and chest portions irregular periods, and hair growth on the chest, face and back (in women) are the most prominent ones. One can also suffer from depression, weakness in legs, and easy bruising as other signs of cortisol overproduction.
Symptoms of aldosterone overproduction
As a result of the overproduction of the aldosterone hormone, people generally have feelings of excessive thirst, feelings of tiredness and weakness and sometimes high blood pressure. The desire of urinating frequently and painful muscle cramps too become evident due to the excessive production of aldosterone.
Symptoms of testosterone overproduction
When as a result of malignant tumors in the adrenal cortex the production of the testosterone hormone goes to higher than normal levels, it is considered to be overproduction. The voice becoming deeper, excessive invasion of acnes, irregular periods become prominently visible symptoms of this kind of adrenal cancer. Even, excessive growth of body hair or the facial hair and heightened muscle mass are some of its common symptoms.
Symptoms of estrogen overproduction
The growth of the breast in males and the early puberty in females are the most common symptoms of adrenal cancer where the malignant tumors overly produce estrogen hormone. Even decreased sex drive or impotence in males can be considered as its other serious symptoms.
Apart from the above mentioned adrenal cancer symptoms, in some cases, the adrenal tumors become so big that they start pressing the nearby organs which leads to signs of abdominal pain or feelings of fullness in the belly. The moment one identifies having any one of the signs discussed here, he or she should look for medical attention immediately. If you wish to discuss about any specific problem, you can consult an Endocrinologist.