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Zin B Capsule Health Feed

Asked for male, 36 years old from Lucknow
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This 33 years old female presented with c/o fever 1 week, breathless weakness, loss of appetite 1 week, bp 110/70mmhg, p/r 1116/min, temp normal, cvs s1+s2 normal, chest right low air entry, cns cons & oriented. Patient investigated & diagnosed as above managed conservatively by iv antibiotics (cefobran, ppi and other symptomatic treatment. Pleural tapping done on 25/02/2020 under la with aseptic precautions from pleural cavity & 1500 ml straw fluid aspirated. Post procedure uneventful. My att started on 29th feb 2020. I am taking same dose since 29th feb 2020. Kindly guide me about dosage whether I have to reduce or take same dosage. Medicine details: rifampicin isoniazid pyrazinamide and ethambutol hydrochloride tablets ip forecox each film coated tablet contains: rifampicin ip                               225 mg isoniazid ip                                  150 mg pyrazinamide ip                         750 mg ethambutol hydrochloride ip 400 mg dosage: 2 tablets per day omez d omeprazole pyridoxine hydrochloride tablets ip 40 mg benadon.

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MBBS, MD - Geriatrics, MRCP-1 (UK), MRCP...read more

General Physician•Jaipur
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ATT is usually taken for 6 months. After 2 months, pyrazinamide is stopped and other medications should be continued.
In your case case, i suggest you to repeat a CXR to look for the response and amount of remaining fluid. Also continue rifampicin, isoniazid and ethambutol for atleast 3 more months. You can stop pyrazimamide.
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MD

General Physician•Delhi
Avoid protein in diet .
PYrazinamide induced hyperuricemia.
You need to start taking febuxostat.
Kindly see your physician .
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I had written to you on 11.03.2015. I have been detected for TB of the lower spine on 24th Jan 2015. Undergoing Anti Tuberculer Treatment since 28.01.2015. 24.02.2015 INH was stopped as I had failed Liver Function Test. On 04.03.2015 ATT was stoped as LFT failed miserably, Billirubin Total-1.32, Direct-0.70, Indirect-0.62 SGOT-868, SGPT-582 LFT on 09.03.2014 bilirubin total- 0.4, direct- 0.24, indirect - 0.16 SGOT (AST)-288.5, SGPT(ALT) - 669.3, GGPT-70.3, Still ATT discontinued. Following medicines were prescribed by doctor for one week. S-AdenosylMethionine 400mg 1 tab 2 times a day Ursodeoxycholic acid ip-450mg 1 tab 2 times a day Zevit- vitamin B complex and C with Zinc Sulphate - once a day Now the latest up-date is given below. 16.03.2015 the test reports are slightly better. Total ? 0.89 max 1.2 Direct-0.26 max 0.20 Indirect- 0.63 max 1.0 SGOT ? 91.3 MAX 35 SGPT ?- 225.5 MAX 46 following medicines were priscribed by doctor for one more week. S-AdenosylMethionine 400mg 1 tab 2 times a day Ursodeoxycholic acid ip-450mg 1 tab 2 times a day Zevit- vitamin B complex and C with Zinc Sulphate - once a day Also prescribed the following Ethambutol Hydrochloride-1200 mg-once a day Levofloxacin - 750mg once a day Refampicin - 450 mg - once a day Report dated 23.03.2015 This week again the test reports are much better. Bilirubin Total ? 0.96 max 1.2 Direct-0.42 max 0.20 Indirect- 0.54 max 1.0 SGOT ? 40.6 MAX 35 SGPT ?- 78.1 MAX 46 To continue with all the above mentioned medicines and he added Pyrazinamide 750mg 2 tablets in a day Further he also informed to take all the ATT medicines together after dinner. LFT dated 30.03.2015 Total ? 1.06 max 1.2 Direct- 0.33 max 0.20 Indirect- 0.73 max 1.0 SGOT ? 441.9 MAX 35 SGPT ?- 727.2 MAX 46 I do not know what the Doctor will say tomorrow as I have failed LFT again. Will ATT be stopped again partially or completely.

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MD - Pulmonary, DTCD

Pulmonologist•Faridabad
Your doctor is treating you very nicely.A very close monitoring required.Your doctor will again stop pyrazinamide.Ask him can he put you on streptomycin
Asked for female, 30 years old from Dehradun
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MBBS, MD TUBERCULOSIS AND CHEST DISEASES...read more

Pulmonologist•Kolkata
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you should take akurit in the night at bedtime. only akurit will not suffice, you should add combutol and pyrazinamide to it. Consult online for detailed discussion.
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