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Overview

Triomune 150 Mg/30 Mg/200 Mg Tablet

Manufacturer: Cipla Ltd
Medicine composition: Lamivudine, Stavudine, Nevirapine
Prescription vs.OTC: Prescription by Doctor required

Triomune 150 Mg/30 Mg/200 Mg Tablet is a nucleoside analogue. It is used in combination with other medications to treat HIV infection. It functions by interfering with the growth of the HIV infection.

On using this medication you may experience side effects such as nausea, joint pain, difficulty sleeping, diarrhea, cough, dizziness, swelling of the mouth, headache, reduced appetite, weakness, vomiting, darkening of the urine, numbness, mental/ mood disorders, ear pain, itchiness, sore throat and chest pain. If your reactions persist or worsen over time seek the help of your health care provider right away.

Before using this medication tell your doctor if: you are allergic to any ingredient contained within Triomune 150 Mg/30 Mg/200 Mg Tablet, you are taking any other medications especially emtricitabine and zalcitabine, you have enlarged liver/ high levels of lactic acid/ abnormal liver functioning/ muscle problems/ kidney problems/ lactic acidosis/ nerve disorder/ pancreas problem, you are overweight, you are pregnant or are planning to become pregnant or are nursing a baby.

The dosage for this medication should be based on your medical history and current condition. The usual dose in adults for HIV infection is about 150 mg twice daily or 300 mg once daily.

hiv infection
In addition to its intended effect, Triomune 150 Mg/30 Mg/200 Mg Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Is It safe with alcohol?
Interaction with alcohol is unknown. Please consult your doctor.
Are there any pregnancy warnings?
Lamivir s 150mg/60mg tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Are there any breast-feeding warnings?
Unknown. Human and animal studies are not available. Please consult your doctor.
Is it safe to drive while on this medicine?
Patients may experience dizziness and/or somnolence, and they should avoid driving or operating machinery.
Does this affect kidney function?
Caution to be advised in patients with moderate to severe impaired renal function.
Dose adjustment is required in patients with underlined renal diseases. Please consult your doctor.
Does this affect liver function?
There is no data available. Please consult doctor before consuming the drug.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.

Popular Questions & Answers

I am suffering from hepatitis B. Most of people are saying that it is quite difficult to be cure it. please help me.

MBBS
General Physician, Mumbai
I am suffering from hepatitis B. Most of people are saying that it is quite difficult to be cure it. please help me.
yes chronic hepatitis b is slightly difficult to cure .It is finally cured by your body's immune system. it can be controlled by prolonged treatment with interferon and lamivudine(antiviral).treatment is aimed at preventing cirrhosis and liver damage.
1 person found this helpful

I am 25 years old man and I am suffering from hepatitis b .this thing I cam to know when I went for a employment so please suggest me the best possible way to come from it.

PDDM, MHA, MBBS
General Physician, Nashik
I am 25 years old man and I am suffering from hepatitis b .this thing I cam to know when I went for a employment so p...
The natural course of chronic hepatitis B progresses through three stages: immune tolerance, active disease, and a late phase with reduced viral replication Approximately 25 per cent of patients with chronic hepatitis B will develop cirrhosis, causing permanent and serious liver damage. Chronic carriers of HBV are far more likely to develop hepatocellularcarcinoma than non-carriers The course of hepatitis B is determined by many factors, including immune response, host genetic factors, and HBV mutations. Treatments include: Antiviral medications. Several antiviral medications — including lamivudine (Epivir), adefovir (Hepsera), telbivudine (Tyzeka) and entecavir (Baraclude) — can help fight the virus and slow its ability to damage your liver. . Interferon alfa-2b (Intron A). . Liver transplant.
1 person found this helpful

I am suffering from hepatitis b from last 5 years need a best doctor for consultation in kolkata please suggest me a best doctor for cure this disease.

PDDM, MHA, MBBS
General Physician, Nashik
Treatments include: Antiviral medications. Several antiviral medications — including lamivudine (Epivir), adefovir (Hepsera), telbivudine (Tyzeka) and entecavir (Baraclude) — can help fight the virus and slow its ability to damage your liver. ... Interferon alfa-2b (Intron A). ... Liver transplant.
1 person found this helpful

I am a 35yr old male and have chronic acidity problem. I am hepatitis B+. What should I do. I already taking HOMEOPATHY treatment from the last 2 YEAR.

MBBS, MD - Internal Medicine
Internal Medicine Specialist, Faridabad
I am a 35yr old male and have chronic acidity problem. I am hepatitis B+. What should I do. I already taking HOMEOPAT...
Acute hepatitis B infection lasts less than six months. Your immune system likely can clear acute hepatitis B from your body, and you should recover completely within a few months. Most people who acquire hepatitis B as adults have an acute infection, but it can lead to chronic infection. Chronic hepatitis B infection lasts six months or longer. When your immune system can't fight off the acute infection, hepatitis B infection may last a lifetime, possibly leading to serious illnesses such as cirrhosis and liver cancer. The younger you are when you get hepatitis B — particularly newborns or children younger than 5 — the higher your risk the infection becoming chronic. Chronic infection may go undetected for decades until a person becomes seriously ill from liver disease. Interferon alfa-2b (Intron A) Antiviral medications. i.e. lamivudine

I'm 39 years old male and carrying hsbag for last 8 yrs. Is there any permanent treatment?

MBBS, MD - Internal Medicine
Internal Medicine Specialist, Faridabad
Acute hepatitis B infection lasts less than six months. Your immune system likely can clear acute hepatitis B from your body, and you should recover completely within a few months. Most people who acquire hepatitis B as adults have an acute infection, but it can lead to chronic infection. Chronic hepatitis B infection lasts six months or longer. When your immune system can't fight off the acute infection, hepatitis B infection may last a lifetime, possibly leading to serious illnesses such as cirrhosis and liver cancer. The younger you are when you get hepatitis B — particularly newborns or children younger than 5 — the higher your risk the infection becoming chronic. Chronic infection may go undetected for decades until a person becomes seriously ill from liver disease. Interferon alfa-2b (Intron A) Antiviral medications. i.e. lamivudine

Popular Health Tips

How Can Hepatitis B and C Be Treated Through Internal Medicine?

MD - Internal Medicine, MBBS
Internal Medicine Specialist, Mumbai
How Can Hepatitis B and C Be Treated Through Internal Medicine?

Hepatitis B and C are considered the world’s chronic viral hepatitis which kills a huge number of people every year. Even though it accounts for massive suffering as well as early death, it could only attract relatively less national and international attention. While the deaths caused by tuberculosis, malaria and HIV/AIDS have reduced to a great extent since the early 2000s, deaths stemming from hepatitis B and C are rising at a fast pace. It kills around 1 million people across the world.

Can medicine help in the treatment of hepatitis B and C?
There are numerous FDA approved medications available for the treatment of Hepatitis B and C. Here are some of the best medicines for this, but before you take them, you must consult an expert who can evaluate your symptoms and recommend the right drugs for you.

Medicines for Hepatitis B:

  1. Entecavir: It is used in chronic hepatitis B virus infection and can treat active viral replication.
  2. Lamivudine: It is used for treating chronic hepatitis B which is associated with Hepatitis B viral replication along with active liver inflammation.
  3. Adefovir dipivoxil: This is used for the treatment of the disease in children below the age 12 years.
  4. Interferon alpha 2B: It can be used for young children aged 1 year who are affected by the disease along with compensated liver disease.
  5. Pegylated interferon: It is used for the treatment of adult patients with HBeAg positive and negative chronic hepatitis. If the patient has compensated liver disease along with liver inflammation and evidence of viral replication, then this medicine is usually given.
  6. Telbivudine: When there is chronic hepatitis with adult patients along with persistent elevations in ALT and AST or previously active disease, this medicine may have to be administered.
  7. Tenofovir alafenamide: It is indicated for the treatment of chronic hepatitis B virus infection in adults with compensated liver disease.

Medicines for Hepatitis C:

  1. Ribavirin: This medicine can be used in combination with other medicines for chronic hepatitis C virus infection. Ribavirin can be utilized for compensated liver disease in patients who have not been treated with interferon alpha.
  2. Daclatasvir: This is an NS5A replication complex inhibitor which is often given with sofosbuvir for the treatment of patients with chronic HCV genotype 3 infection.
  3. Sofosbuvir and Velpatasvir: The combination of these two medicines is used for the treatment of adult patients with chronic genotype 1 to 6 without any infection. It may be used in combination with ribavirin in patients with compensated or decompensated cirrhosis.
  4. Ledipasvir: A fixed-dose of a combination of hepatitis C virus inhibitor and Ledipasvir can be employed in the treatment of hepatitis genotype 1 infection in adults.

Both in the cases of Hepatitis B and C, it is important to diagnose the infection early. Prevention and cure are possible with precautionary measures and prescribed medications.

In case you have a concern or query you can always consult an expert & get answers to your questions!

5871 people found this helpful

Hiv Treatment

MD - General Medicine
Sexologist, Delhi
Hiv Treatment

HIV treatment is done by antiviral drugs, there are number of antiviral drugs available in the market, usually HIV is treated with combination of drugs, usually two to three drugs are used in treating HIV in initial stage, we can change the combination of drugs according to requirement of the patient. Drugs can be adjusted or increased if there is resistance of HIV in the patient.

There are number of compounds (about 22 in number) which have been formally approved (by the US Food and Drug Administration) for the treatment of HIV infections (AIDS). According to their point of intervention with the HIV replicative cycle, these compounds can be classified in 5 categories: (1) NRTIs (nucleoside reverse transcriptase inhibitors): azidothymidine, didanosine, zalcitabine, stavudine, lamivudine, abacavir and emtricitabine; (2) NtRTIs (nucleotide reverse transcriptase inhibitors): tenofovir, administered as its oral prodrug form TDF (tenofovir disoproxil fumarate); (3) NNRTIs (non-nucleoside reverse transcriptase inhibitors): nevirapine, delavirdine and efavirenz; (4) PIs (HIV protease inhibitors): saquinavir, ritonavir, indinavir, nelfinavir, amprenavir, lopinavir, atazanavir, fosamprenavir, tipranavir and darunavir; and (5) FIs (fusion inhibitors): enfuvirtide. Starting from the drugs which are currently available for the treatment of AIDS, numerous combinations could be envisaged. Drug combinations are, in principle, aimed at obtaining synergism between the compounds (reasonably expected if they act by different mechanisms), while reducing the likelihood for drug resistance development. Such anti-HIV drug combination regimens were initiated about 10 years ago and have been generally referred to as HAART (for highly active antiretroviral therapy). While HAART originally consisted of a pill burden of twenty (or more) pills per day, this has been gradually diminished over the past few years, and, since July 2006, a all-in-one pill (teevir from myelin and virotrenz from Ranbaxy sun pharma) has become available, which contains three anti-HIV drugs (tenofovir disoproxil fumarate 300 mg, emtricitabine200mg and efavirenz 600 mg) to be taken as a single pill only once daily. Given the information that has been acquired on the therapeutic use (efficacy, safety) of tenofovir disoproxil fumarate over the past five years, it would now seem mandatory to further consider the prophylactic use of TDF [and its combination with emtricitabine (Truvada) and/or Atripla], as a single daily pill to prevent HIV infection. New combinations of drugs are also available which include tenofovir 300 mg lamivudine 150 mg which are very new drugs.

Now a days we can treat patients who had sex with some sex worker or any male transgender or some unknown person and during sexual intercourse condom gets bursted , we can treat them if they come to us within 72 hours of direct contact, these medicines are called POST-EXPOSURE PROPHYLAXIS (PEP) drugs for HIV or prophylactic treatment for HIV, by using these drugs we can treat a patient and we can stop transfusion of HIV virus to the person.

PEP involves taking anti HIV drugs as soon as possible after having been exposed to unprotected sex with some sex worker or transgender or with homosexual PrEP is a new HIV prevention method in which people who do not have HIV infection take pills of medicine daily to reduce the risk of becoming infected with HIV virus ,PEP should be taken within 72 hours of exposure to unprotected sex before the virus has time to rapidly duplicate in your body, PEP consists of 2-3 antiretroviral drugs taken for 28 days.

4 people found this helpful

HIV Infection and AIDS Treatment

MD - General Medicine
Sexologist, Delhi
HIV Infection and AIDS Treatment

If an HIV infection, treatment is primarily aimed at preventing evolve as long as possible and do not give way to the disease AIDS . In this case, the treatment is against HIV itself. If the emergence of AIDS and its accompanying diseases occur as a lung inflammation or bowel, treatment should include them. It is important to maintain a healthy lifestyle so that the immune system does not see further harmed. Many infected with HIV also have counseling and self-help centers with other affected. Drug Treatments Currently it has good information about certain steps in the single expansion of HIV infection. Thus, it has been possible to develop drugs that inhibit certain evolutions of cell infestation. HIV treatment is also called highly active antiretroviral therapy and its abbreviation is HAART. Specifically, this treatment includes the following medications: The entry inhibitors , which inhibit the entry of 'HIV virus' in human cells. VHI prevent adhesion of immune cells and / or dissolution of the viral envelope with the cell membrane (fusion). The excipient enfuvirtide eg prevents fusion. The reverse transcriptase inhibitor blocks a special top virus that can translate the genetic information of the virus (DNA) reverse transcriptase. This group of drugs includes, for example, substances such as lamivudine , the tenofovir or nevirapine . Another top virus, integrase, incorporating HIV DNA genetic information translated into immune cells. In this case, inhibitors of this enzyme, apply called integrase inhibitors . The drug raltegravir contains these integrase inhibitors. The protease inhibitors destroy other HIV enzyme, the HIV protease. If a cell is infected with HIV, forms a component of protein which could be born new HIV viruses. Protease HIV plays an important role in the composition of this protein. Inhibitors of this enzyme are involved in virus appear less capable of action in affected cells. Examples of protease inhibitors are drugs fosamprenavir , indinavir , nelfinavir, and ritonavir . Although 'AIDS' remains an incurable disease, it may be well with a combination therapy . This combination consists of at least three different drugs; usually several inhibitors of reverse transcriptase which are combined with a protease inhibitor.

 

1 person found this helpful

How is Hiv Treatment ?

MD - General Medicine
Sexologist, Delhi
How is Hiv  Treatment ?

Hiv treatment is done by antiviral drugs, there are a number of antiviral drugs available in the market, usually HIV is treated with a combination of drugs, usually two to three drugs are used in treating HIV in the initial stage, we can change the combination of drugs according to the requirement of the patient. Drugs can be adjusted or increased if there is the resistance of HIV in the patient.

There are a number of compounds (about 22 in number) which have been formally approved (by us food and drug administration) for the treatment of HIV infections (aids). According to their point of intervention with the HIV replicative cycle, these compounds can be classified into 5 categories: (1) nrtis (nucleoside reverse transcriptase inhibitors): azidothymidine, didanosine, zalcitabine, stavudine, lamivudine, abacavir and emtricitabine; (2) ntrtis (nucleotide reverse transcriptase inhibitors): tenofovir, administered as its oral prodrug form tdf (tenofovir disoproxil fumarate); (3) nnrtis (non-nucleoside reverse transcriptase inhibitors): nevirapine, delavirdine and efavirenz; (4) pis (hiv protease inhibitors): saquinavir, ritonavir, indinavir, nelfinavir, amprenavir, lopinavir, atazanavir, fosamprenavir, tipranavir and darunavir; and (5) fis (fusion inhibitors): enfuvirtide. Starting from the drugs which are currently available for the treatment of aids, numerous combinations could be envisaged. Drug combinations are, in principle, aimed at obtaining synergism between the compounds (reasonably expected if they act by different mechanisms), while reducing the likelihood of drug resistance development. Such anti-hiv drug combination regimes were initiated about 10 years ago and have been generally referred to as haart (for highly active antiretroviral therapy). While haart originally consisted of a pill burden of twenty (or more) pills per day, this has been gradually diminished over the past few years, and, since July 2006, an all-in-one pill (teevir from myelin and virotrenz from ranbaxy sun pharma) has become available, which contains three anti-hiv drugs (tenofovir disoproxil fumarate 300 mg, emtricitabine200mg and efavirenz 600 mg) to be taken as a single pill only once daily. Given the information that has been acquired for the therapeutic use (efficacy, safety) of tenofovir disoproxil fumarate over the past five years, it would now seem mandatory to further consider the prophylactic use of tdf [and its combination with emtricitabine (truvada) and/or atripla], as a single daily pill to prevent HIV infection. New combinations of drugs are also available which include tenofovir 300 mg lamivudine 150 mg which is very new drugs.

Now a days we can treat patients who had sex with some sex worker or any male transgender or some unknown person and during sexual intercourse condom gets bursted, we can treat them if they come to us within 72 hours of direct contact, these medicines are called post-exposure prophylaxis (pep) drugs for hiv or prophylactic treatment for hiv, by using these drugs we can treat a patient and we can stop transfusion of hiv virus to the person.

Pep involves taking anti hiv drugs as soon as possible after having been exposed to unprotected sex with some sex worker or transgender of with homosexual prep is a new hiv prevention method in which people who do not have hiv infection take pills of medicine daily to reduce the risk of becoming infected with hiv virus, pep should be taken within 72 hours of exposure to unprotected sex before the virus has time to rapidly duplicate in your body, pep consists of 2-3 antiretroviral drugs taken for 28 days.

1 person found this helpful

HIV - Understanding Its Relation With Tuberculosis!

MBBS, PGDHS,PGDHIVM
General Physician, Nalgonda
HIV - Understanding Its Relation With Tuberculosis!

HIV and tuberculosis (TB) are two life-threatening and common diseases in the world. The two diseases are very closely connected so much so that their occurrence is normally labeled as a co-epidemic. In most cases tuberculosis is found to be the most transmissible contagion in HIV-Immunocompromised victims, proving to be the cause of their death.

What is HIV?
Human Immunodeficiency Virus, more commonly known by its abbreviation HIV, is a virus that attacks the immune system, which is the body's natural defense against illnesses. The virus terminates a kind of white blood cells (WBCs) in the immune system known as the T-helper cell also known as CD4 cells. This virus then proceeds to duplicate itself within these cells.

As HIV reduces the T-helper cells, by duplicating at an increasing rate, it slowly breaks down the patient’s immune system. This leaves the individual susceptible to other deadly diseases such as tuberculosis. HIV infection is a permanent disease with three phases of progression. HIV medications can reduce or stop the evolution of the disease from one phase to another. The treatment can also decrease the chances of spreading HIV to other people.

What is tuberculosis (TB)
Tuberculosis is a transmittable disease triggered by the presence of bacterium known as Mycobacterium tuberculosis. It is still considered a deadly disease in most developing countries where treatment is scarce. Generally, TB affects the lungs but it can also affect other parts of the body. Symptoms include – coughing with blood, fever, night sweats and loss of weight.

The relation between TB and HIV
In second world countries, most patients infected with HIV suffer from TB as the initial indicator of AIDS. Tuberculosis can occur at any phase of the HIV infection. The danger and severity of tuberculosis rises rapidly after infection with HIV. Even though tuberculosis can be a fairly primary indicator of HIV infection, it is imperative to observe that the risk of tuberculosis increases as the CD4 cell count reduces along with the progression of the HIV infection.

Treatment
Positive treatment for TB usually entails 6 months of rigorous therapy. HIV patients with TB usually respond well to this therapy, if the regimen comprises INH and a rifamycin for the period of TB therapy and cure. TB generally reappears when the immune system is unable to respond to stop the development of mycobacteria. The cytokine IFN-γ plays a key role in the response of the immune system all through the contagion.
HIV and TB infections area two-directional communication of the two pathogens. TB is one of the main causes of disease and fatality among patients with HIV in Africa and other severely affected regions. With almost a 50% kill rate around the world, raising awareness about this disease and consulting doctors when signs or symptoms appear is vital in reducing the extent of this epidemic.

Rifampicin- HIV treatment are complicated by the fact that one of the key drugs used in TB treatment, rifampicin, reduces blood levels of nevirapine (Viramune) by 30 to 55% and also reduces levels of most protease inhibitors.

In case you have a concern or query you can always consult an expert & get answers to your questions!

3081 people found this helpful

Table of Content

About Triomune 150 Mg/30 Mg/200 Mg Tablet
When is Triomune 150 Mg/30 Mg/200 Mg Tablet prescribed?
What are the side effects of Triomune 150 Mg/30 Mg/200 Mg Tablet?
Key highlights of Triomune 150 Mg/30 Mg/200 Mg Tablet
What are the interactions for Triomune 150 Mg/30 Mg/200 Mg Tablet?