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Pyzina 300 MG Tablet Health Feed

Asked for male, 29 years old from Mumbai
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Hello Doctor, I was diagnosed with Pulmonary TB about a month ago and began with the treatment in april end .The only symptom I had was rubbing around rib cage while taking deep breaths. Except for that, I did not have any cough, fever or even weight loss. During diagnosis , genexpert report showed that I was not resistant to rifampicin. After a month of treatment , on 27th may I experienced mild fever of about 99 deg C. But when it didn't go away I took paracetamol after the advice of my physician. The fever continued and I occasionally experienced sweats when I slept. When the fever didn't improve, my doctor checked me for malaria and found nothing in the tests. He also asked me for a new chest xray and saw a slight amount of improvement in the TB scar compared to earlier xray. An AFB test using pleural fluid came negative. He then advised me to take levoflox 750 for a week. Today, is the 6th day of levoflox and my condition of fever has slightly improved but the fever still comes back around in the late afternoon and then I take a paracetamol to avoid it's rise. Other than fever, I don't have any other symptoms. I have attached the latest reports respectively for my tests. Following are the medicines I was prescribed to and I have been taking them regularly. Tab. C.Rcinex 600 - empty stomach Tab. Pyzina 1gm and benadon 40 mg - After breakfast Tab. Cumbotol - after lunch Tab. Pyzina 750 mg - after dinner. Thank you very much,

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Diploma in Tuberculosis and Chest Diseas...read more

Pulmonologist•Delhi
Some feverish feeling or fever can persist for up to two months and sometimes up to three months, so continue taking treatment
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Asked for female, 45 years old from Bangalore
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I am taking treatment for tuberculosis. I am taking medications from the past 3 months. In the beginning doctor gave the following medication (for 8 days) 1. Rifampicin - 450 mg 2. Ethambutol - 600 mg 3. Isoniazid - 200 mg 5. Benadon - 20 mg 6. Pyrazinamide - 1000 mg then liver got affected so he put me on this for a week (7 days) (i got drug induced hepatitis) 1. Ethambutol - 600 mg 2. Levoflox 750 mg 3. Injection amikacin 500m mg (iv) then again for one week (7 days) he gave, 1. Ethambutol - 600 mg 2. Levoflox 750 mg 3. Injection amikacin 500m mg (iv) 4. Isoniazid - 100 mg taking isoniazid again affected the liver, so he stopped isoniazid and he gave this for 5 weeks, 1. Ethambutol - 600 mg 2. Levoflox 750 mg 3. Injection amikacin 500m mg (iv) then when the liver condition became ok, doctor has given the following medication 1. Rifampicin - 450 mg 2. Ethambutol - 600 mg 3. Isoniazid - 200 mg 4. Benadon - 20 mg 5. Levoflox 750 mg this is what is going on now. I am not sure if the treatment being given is right or not. I had consulted another pulmonologist who says this is not the right treatment as drugs should not be changed so often. Also he says amikacin and levoflox are given for mdr tb and not for normal tb. Now that it is already given I cannot change that. The other pulmonologist says that if it is these drugs then one needs to give it for 9 months as pyrazinamide is not given. He also says if sputum is negative then we can stop levofloxin and give the drugs for 4 months. However I am not getting sputum for testing also. I have two questions now. 1. Other than sputum testing is there any other way of finding out if tb bacteria is still there in the body. If that is the only way is there any way of generating sputum. 2. Should att-4 with the four standard medications be started again. What is the best alternative. Kindly suggest.

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M.D - Respiratory Medicine

Pulmonologist•Hyderabad
Pulmonologist altered regimen and added levofloxacin because you had liver side effects with pyrazinamide which was stopped
the standard regimen of rifampicin isoniazid ethambutol pyrazinamide is a guideline with exception when necessary
it is not an inviolable dictate
still in doubt consult pulmonologist at nationaltb institute bangalore malleswaram.
Asked for male, 36 years old from Lucknow
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This 33 years old female presented with c/o fever 1 week, breathless weakness, loss of appetite 1 week, bp 110/70mmhg, p/r 1116/min, temp normal, cvs s1+s2 normal, chest right low air entry, cns cons & oriented. Patient investigated & diagnosed as above managed conservatively by iv antibiotics (cefobran, ppi and other symptomatic treatment. Pleural tapping done on 25/02/2020 under la with aseptic precautions from pleural cavity & 1500 ml straw fluid aspirated. Post procedure uneventful. My att started on 29th feb 2020. I am taking same dose since 29th feb 2020. Kindly guide me about dosage whether I have to reduce or take same dosage. Medicine details: rifampicin isoniazid pyrazinamide and ethambutol hydrochloride tablets ip forecox each film coated tablet contains: rifampicin ip                               225 mg isoniazid ip                                  150 mg pyrazinamide ip                         750 mg ethambutol hydrochloride ip 400 mg dosage: 2 tablets per day omez d omeprazole pyridoxine hydrochloride tablets ip 40 mg benadon.

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MBBS, MD - Geriatrics, MRCP-1 (UK), MRCP...read more

General Physician•Jaipur
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ATT is usually taken for 6 months. After 2 months, pyrazinamide is stopped and other medications should be continued.
In your case case, i suggest you to repeat a CXR to look for the response and amount of remaining fluid. Also continue rifampicin, isoniazid and ethambutol for atleast 3 more months. You can stop pyrazimamide.
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