Question

I was diagnosed with dm 2 about two years back. Iam on amaryl-m1 bd & has hba1c of 7. I started feeling extra sensation under the feet, heaviness in foot, leg, thighs from about a month or two, some pain in hip area and finally difficulty in lifting one leg about 2 weeks days back along with knee weakness in one leg although other leg has been affected to a lesser extent till date. I never experienced very sharp pain & 2 weeks back had mild pain in my buttocks for about a week. The loss of movement in the 2 directions direction in the leg & knee weakness was quite quick about 10-12 days back. Now I do not feel any pain but had some falls primarily on account of knee weakness or weakness in right leg. Mri scan, ct scan were ok but problem was reported in nerve conduction test in both legs but mainly in right leg. Was diagnosed with peripheral neuropathy or diabetic amyotrophy which correlates with my overall symptoms. Doctor put me on 8 day course of prednisone (40mg-10mg) with insulin. My sugar with amaryl m1 as on now is under control & I take light food with reasonable physical activity & sugar levels now seems to be ok 92 fasting /140 pp. Also started visiting a physiotherapist from today. As of know there is appears to be some improvements in my walking (can walk 15-20 min at a stretch inside home) though weakness in one leg & knee persist. I cannot drive due to difficulty in movement of my right leg when trying to move it sideways while sitting. It is also not possible to lift the right leg against gravity when laying down though backward lifting & movement on sideways when lying on one side are intact. Have been prescribed pregaba m 75 (hs, neurkind+. Have no pain of any type. My questions 1) has peripheral neuropathy reached a plateau ie. Stopped or not 2) is pregabalin needed in my case as I have no pain, i. E. Whether it play a role in nerve regeneration or is overall beneficial in such situation 3) can I expect improvement in my right leg in 1-2 months time with sugar control & exercises.

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General Physician•

1. Peripheral neuropathy is a on going process even in normal individuvals as age advances due to deficiency of vitamins mainly b12
2. In your case pregabalin is needed for some time 3. Nerve regeneration is impossible for anyone 4. Definitely you can expect improvement in the right leg in 1-2 months with good control of sugar & exercises.

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Dr.M. Sathyavenkatesan · Accepted Answer

1. Peripheral neuropathy is a on going process even in normal individuvals as age advances due to deficiency of vitamins mainly b12
2. In your case pregabalin is needed for some time 3. Nerve regeneration is impossible for anyone 4. Definitely you can expect improvement in the right leg in 1-2 months with good control of sugar & exercises.

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