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Overview

Nicardia 20 MG Tablet

Manufacturer :  Jb Chemicals
Medicine Composition :  Nifedipine
Prescription vs OTC : Prescription by Doctor not required

About Nicardia 20 MG Tablet

Nicardia 20 MG Tablet aids in the effective treatment of high blood pressure (hypertension) as well as pain in the chest (angina). This medicine belongs to a drug group that effectively slows down the calcium activity in the blood vessels. Therefore, it helps in relaxing the heart muscles by increasing the flow of blood.

This drug should only be taken if it is prescribed by a doctor. Detailed information on current health problems, allergies as well as medication should be provided before the drug is prescribed.

For instance, patients suffering from a severe case of coronary artery disease are generally not prescribed with this medication. It is also not prescribed to the patients who have recently had a heart attack.

As it is not yet clear that this medication harms a fetus, women who are pregnant or are planning to conceive should inform their medical practitioner before starting this drug. In case this medication needs to be discontinued, it should be done gradually. Stopping the drug suddenly can aggravate the condition resulting in severe consequences.

The primary cardiac symptoms of calcium blocker overdose include hypotension and bradycardia. The hypotension is caused by peripheral vasodilation, myocardial depression, and bradycardia. Bradycardia results from sinus bradycardia, second- or third-degree atrioventricular block, or sinus arrest with junctional rhythm. Intraventricular conduction is usually not affected so QRS duration is normal.

In a few reported cases, overdose with calcium channel blockers has been associated with hypotension and bradycardia, initially refractory to atropine but becoming more responsive to this agent when larger doses (approaching 1 g/hour for more than 24 hours) of calcium chloride was administered.

Take as directed; do not alter dosage regimen or increase, decrease, or discontinue without consulting prescriber. Do not crush or chew tablets or capsules. Consult prescriber before increasing exercise routine (decreased angina does not mean it is safe to increase exercise).

Change position slowly to prevent orthostatic events. May cause dizziness or fatigue; use caution when driving or engaging in tasks that require alertness until response to drug is known. Maintain good oral care and inspect gums for swelling or redness.

May cause frequent urination at night. Report irregular heartbeat, swelling, difficulty breathing or new cough, unresolved fatigue, unusual weight gain, unresolved dizziness or constipation, and swollen or bleeding gums.

    What are the uses of Nicardia 20 MG Tablet

    What are the contraindications of Nicardia 20 MG Tablet ?

    What are the side effects of Nicardia 20 MG Tablet ?

    Key highlights of Nicardia 20 MG Tablet

    • How long is the duration of effect?

      This effect of this medicine lasts for a duration of approximately 6 to 8 hours.

    • What is the onset of action?

      The peak effect of this medicine can be observed in 30 to 120 minutes for a conventional tablet and 6 hours for an extended release tablet.

    • Are there any pregnancy warnings?

      This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Are there any breast-feeding warnings?

      This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

    • Does this affect kidney function?

      This medicine is found to be safe to use in patients with kidney disease. Adjustment of the dose is not needed. However, consult to your doctor before taking it, whereas supplemental dose is not necessary.

    • Does this affect liver function?

      Caution must be taken in a patient with liver disease. Adjustment of dose must be needed. Kindly consult your doctor before taking it. Reduce oral dose by 50% to 60% in patients with cirrhosis.

    • Is It safe with alcohol?

      Consumption of alcohol must be avoided while taking this medicine.

    • Is it safe to drive while on this medicine?

      This medicine affects the consciousness of the patient. Thus driving must be avoided while taking it.

    What are the substitutes for Nicardia 20 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Nicardia 20 MG Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Missed Dose instructions

      The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of overdose.

    How does this medication work?

    Nicardia 20 MG Tablet is a calcium channel blockers. It works by inhibiting the entry of calcium into the cardiac and vascular smooth muscles and prevents the contraction of the muscles and thereby reduces the blood pressure.

      What are the interactions of Nicardia 20 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Ethanol increased Nicardia 20 MG Tablet AUC by 53%; watch for a greater hypotensive effect.
      • Interaction with Medicine

        • Beta-blockers may have increased pharmacokinetic or pharmacodynamic interactions with nifedipine.
        • Calcium may reduce the calcium channel blocker's effects, particularly hypotension.
        • Cimetidine reduced diltiazem's metabolism; consider an alternative H2 antagonist.
        • Cisapride increases nifedipine's effects; monitor blood pressure.
        • Nafcillin decreases plasma concentration of nifedipine; avoid this combination.
        • Phenobarbital reduces the plasma concentration of nifedipine. May require much higher dose of nifedipine.
        • Protease inhibitor like amprenavir and ritonavir may increase nifedipine's serum concentration.
        • Quinidine's serum concentration is reduced and nifedipine's is increased; adjust doses as needed.
        • Rifampin increases the metabolism of the calcium channel blocker; adjust the dose of the calcium channel blocker to maintain efficacy.
        • Tacrolimus's serum concentrations are increased by verapamil; avoid the combination. Use another calcium channel blocker or monitor tacrolimus trough levels and renal function closely.
        • Vincristine's half-life is increased by nifedipine; monitor closely for vincristine dose adjustment.
      • Interaction with Food

        Consumption of grapefruit juice is not recommended as it increases the concentration of Nicardia 20 MG Tablet. Grapefruit juice increases the bioavailability of nifedipine; monitor for altered nifedipine effects. Inform the doctor if you experience dizziness, headache, swelling of hands and feet is necessary.
      • Interaction with Disease

        Blood pressure lowering should be done at a rate appropriate for the patient's condition. Rapid drops in blood pressure can lead to arterial insufficiency. Increased angina and/or MI has occurred with initiation or dosage titration of calcium channel blockers. Use caution in severe aortic stenosis. Use caution in patients with severe hepatic impairment (may need dosage adjustment). Abrupt withdrawal may cause rebound angina in patients with CAD. Use caution in CHF (may cause worsening of symptoms).

      FAQs about Nicardia 20 MG Tablet

      • Ques : What is Nicardia 20 mg tablet?

        Ans : Nicardia 20 MG Tablet is used to treat high blood pressure and other heart complications. The medicine should be taken in conjunction with a proper diet and regular exercise. It contains Nifedipine as an active ingredient. Nicardia 20 MG Tablet works by widening the blood vessels to allow easy blood flow, which lowers the blood pressure and reduces chest pain.

      • Ques : What is the use of Nicardia 20 mg tablet?

        Ans : Nicardia 20 MG Tablet is used for the treatment and prevention from conditions and symptoms of diseases like high blood pressure, hypertension, chest pain, and uterine relaxant. Besides these, it can also be used for treating conditions like a migraine and angina pectoris. The patient should inform the doctor about any ongoing medications and treatment before using Nicardia 20 MG Tablet to avoid undesirable effects.

      • Ques : What are the side effects of Nicardia 20 mg tablet?

        Ans : This is a list of possible side-effects which may occur due to the constituting ingredients of Nicardia 20 MG Tablet. This is not a comprehensive list. These side-effects have been observed and not necessarily occur. Some of these side-effects may be serious. These include swelling of ankles and legs, dizzy, agitation, trembling, and palpitation. Apart from these, using this medicine may further lead to visual disturbances, headache, fainting, restlessness, and flushing. If any of these symptoms occur often or on daily basis, a doctor should be urgently consulted.

      • Ques : What are the instructions for storage and disposal of Nicardia 20 mg tablet ?

        Ans : Nicardia 20 MG Tablet should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets. A doctor should be consulted regarding the dosage of Nicardia 20 MG Tablet. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects.

      • Ques : How long do I need to use nicardia 20 mg tablet before I see improvement in my condition?

        Ans : This medication should be consumed, until the complete eradication of the disease. Thus it is advised to use, till the time directed by your doctor. Also taking this medication longer than it was prescribed, can cause an inadequate effect on the patient's condition. So please consult your doctor.

      • Ques : At what frequency do I need to use nicardia 20 mg tablet?

        Ans : "This medication is generally used once or twice a day, as the time interval to which this medication has an impact, is around 12 to 24 hours, but it is not the standard frequency, for using this medication. It is advised to consult your doctor before the usage, as the frequency also depends on the patient's condition. "

      • Ques : Should I use nicardia 20 mg tablet empty stomach, before food or after food?

        Ans : This medication is common to be taken orally and the action of salts involved in this medication, do not depend on whether taking it pre-meal or post-meal. It is advised to consult a doctor before use and take it at a fixed time in a day.

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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