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Prescription vs.OTC: Prescription by Doctor required
Last Updated: March 21, 2022

Morphine is a narcotic drug that is prescribed for instant pain relief. It is generally used as a pre-anaesthetic medication to reduce acute and chronic pain during surgery, labour and other pain intensive disease/procedures. It works by directly affecting the Central Nervous System.

Morphine is an opiate type naturally found substance in the bodies of several plants and animals. It helps to relieve both acute and chronic pain. Also, it is used as preanesthetic medication.

The medication is available in both oral (pill) and injected directly into the vein (injection) form. However, it is a controlled substance which means its consumption needs to be done under strict supervision. This is because it can be a habit-forming medication that can cause addiction.

It can also help to reduce immense pain and discomfort due to myocardial infarction and even intolerable aches of cancer. This medication is also helpful in relieving dyspnea of acute left ventricular failure and pulmonary edema.

Morphine must be used with caution during pregnancy and breastfeeding as the drug is known to be excreted in human milk. Morphine can be injected directly into the vein (intravenous), or taken orally in the form of a tablet of solution.

Morphine also belongs to a class of drugs called narcotics, and the intake of morphine on a regular basis turns into an addiction. This leads to drug abuse which may cause immense health complications, and eventually death. You should also abstain from alcohol totally to avoid any kind of fatal complications.

Side effects of morphine include both physical and mental discomforts. These include vomiting, persistent nausea, dry mouth, irregular menstrual periods, decreased sexual urge, dizziness, depression and substance abuse and dependence.

Do not use morphine in case of head injury, tumour, seizures, asthma, sleep apnea, chronic obstructive pulmonary disease, gallbladder disease, kidney disease, liver disease, mental/mood disorders. Also if you have a family history of substance abuse, constipation, diarrhoea, pancreatitis, enlarged prostate it is advised to avoid the use of morphine.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

The medication is primarily used for the following conditions:

  • Pain Relief

  • Preanesthetic

  • Hypersensitivity

  • Increased Intracranial Pressure

  • Respiratory Depression

Possible side effects of this tablet are as follows:

  • Is It safe with alcohol?

    This medicine may cause excessive drowsiness and calmness with alcohol.
  • Are there any pregnancy warnings?

    This medicine may be unsafe to use during pregnancy.
    Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
  • Are there any breast-feeding warnings?

    It is probably unsafe to use during breastfeeding. Please consult your doctor.
  • Is it safe to drive while on this medicine?

    Caution is advised when driving or operating machinery.
  • Does this affect kidney function?

    Contraindicated in patients with moderate to severe impaired renal function.
  • Does this affect liver function?

    There is no data available. Please consult doctor before consuming the drug.
  • What is the onset of action?

    The effect of this medicine will be initiated within 30 - 60 minute after its administration.
  • How long is the duration of effect?

    This medicine will remain active and produce its action for about 4 - 7 hours depending on the route of its administration.
  • Are there any missed dose instructions?

    If you miss a dose of Morphine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
  • Are there any overdose instructions?

    Consult your doctor in case of overdose.

Below is the list of medicines, which contains Morphine as ingredient

This medication affects the central nervous system directly and by blocking the pain signals to the brain reduces the pain felt.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Alcohol

    Patient must avoid or limit the consumption of alcohol as this may causes additive CNS effects. One must watch for sedation effect after its consumption.
  • Interaction with Medicine

    Increased toxicity: CNS depressants, tricyclic antidepressants may potentiate the effects of morphine and other opiate agonists; dextroamphetamine may enhance the analgesic effect of morphine and other opiate agonists.
  • Interaction with Food

    Sugar and sugar incorporated food items must be avoided. As glucose may cause hyperglycemia. Monitor blood glucose concentration regularly.
  • Interaction with Disease

    • Use with caution in patients with impaired respiratory function or severe hepatic dysfunction and in patients with hypersensitivity reactions to other phenanthrene derivative opioid agonists (codeine, hydrocodone, hydromorphone, levorphanol, oxycodone, oxymorphone).
    • Morphine shares the toxic potential of opiate agonists and usual precautions of opiate agonist therapy should be observed.
    • Morphine may cause hypotension in patients with acute myocardial infarction. Tolerance or drug dependence may result from extended use.

Ques: What is Morphine?

Ans: Morphine is a pain-relieving drug that acts directly upon the Central Nervous System.It helps to relieve both acute and chronic pain. Also, it is used as preanesthetic medication.

Ques: What are the uses of Morphine?

Ans: Morphine is used commonly to reduce pain during labour. It can also help to reduce immense pain and discomfort due to myocardial infarction and even intolerable aches of cancer.

Ques: What if I forgot to take a dose of Morphine on a scheduled time?

Ans: You must not miss a dose for this drug, however, in case you miss it, please take it as soon as you remember. You can skip the missed dose if it is already time for the next scheduled dose.

Ques: Is Morphine safe for use in pregnancy?

Ans: This medicine should be avoided by pregnant ladies as it can potentially harm the baby. Consult a doctor before using it.

Ques: I am currently breastfeeding a baby. Can I take Morphine?

Ans: It is recommended to consult a doctor before taking this drug if you are breastfeeding a baby. Studies reveal that Morphine is not safe to use during breastfeeding.

Ques: At what time intervals should the dose of Morphine be taken?

Ans: This medicine will remain active and produce its action for about 4 - 7 hours depending on the route of its administration.

Ques: Are there any precautions that need to be taken, while taking Morphine?

Ans: In the beginning of treatment, consumption of Morphine may cause dizziness and drowsiness. It is advised not to work with machinery or tools or drive if there’s an issue in being alert. Consumption of alcoholic beverages is prohibited during treatment with Morphine as it might increase sleepiness/dizziness.

Ques: Can patients suffering from kidney problems take Morphine?

Ans: This drug should be avoided by patients with moderate to severe impaired kidney function. Consult a doctor to know a safer alternative for this drug.

Ques: After how much time can the effect of Morphine be seen?

Ans: The effect of this medicine will be initiated within 30 - 60 minute after its consumption.

Ques: What are the side-effects of Morphine?

Ans: The common side-effects that can be seen includes Dizziness, Sleepiness, Headache, Vomiting, Constipation, Nausea, etc.

Ques: Does Morphine cause addiction?

Ans: Yes, Morphine belongs to a class of drugs called narcotics, which can cause addiction if taken on a regular basis without any medical supervision.

Ques: Can you crush or chew the medications?

Ans: No, consume the medication as a whole without doing any physical change in the medication.

Ques: Can you suddenly stop the consumption of Morphine?

Ans: No, sudden elimination of the treatment may increase the chances of the disease coming back. Continue to use this drug until completion of the maximum amount suggested even though the symptoms disappear after the medicine has begun.

Ques: Is Morphine safe for small children and infants?

Ans: The effects of the product on infants and young children has not been studied yet. We recommend you consult your doctor before making any decision.

Ques: Is Morphine an OTC medicine?

Ans: No, it is not an OTC (over the counter) medication as it is a controlled substance that only needs to be taken under the prescription or supervised by the doctor.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MBBS, Master in Healthcare Administration, Diploma in Occupational Health
General Physician
Table of Content
About Morphine
What are the uses of Morphine
What are the contraindications of Morphine ?
What are the side effects of Morphine ?
Key highlights of Morphine
What are the dosage instructions?
Medicines containing Morphine
How does this medication work?
What are the interactions of Morphine ?
FAQs about Morphine