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Methotrexate 2.5 MG Tablet Health Feed

Know More About Insulin!

Dr. Sunita Sayammagaru 88% (253 ratings)
MBBS, MRCGP ( UK), Diploma in Diabetes (UK), DFSRH (UK), DRCOG (UK), CCT (UK)
Endocrinologist, Hyderabad
Know More About Insulin!

We hear about it in relation to weight, energy levels and diabetes, but what exactly is its schtick and how does it affect our body functioning? Insulin is one of the great discoveries of modern medicine and it instantly led to lives being saved. The first [diabetes] patient was injected with insulin in 1922 – it's one of the great wonder drugs and [without it] those type 1 diabetes patients would all die.

Basically, insulin is a hormone that's produced by beta cells in the pancreas and prompts our cells to take up glucose (from ingested carbohydrates) from the bloodstream. If you don't have enough insulin, the glucose stays in your bloodstream, which reduces the energy made in your body.

Most carbohydrates contain a type of sugar known as glucose. After we finish eating, the carbohydrates break down into smaller sugar molecules called glucose inside the digestive tract. The pancreas is about 6 inches long and sits across the back of the abdomen, behind the stomach. The head of the pancreas is on the right side of the abdomen and is connected to the duodenum (the first section of the small intestine) through a small tube called the pancreatic duct. This gland produces a hormone named Insulin. When the glucose molecules are released into our bloodstream, this insulin helps the cells throughout our body to soak up these simple sugar molecules and use them for providing the body with energy. Now that our base is clear, let’s move on to the importance of insulin in our body.

Why it is important?

Insulin helps our body to absorb glucose and provides the body with all the energy to do what it does. Another really important task that insulin does is balance the glucose levels in our blood. As soon as there is extra glucose in our blood-stream, insulin gives a signal in which the excess glucose is stored in the liver for future use, i.e, in situations when blood sugar drops and the body needs an extra energy boost.

Occurrence of diabetes

In a certain turn of events, when the body refuses to use the insulin properly or in worse cases, the body fails to produce enough insulin, diabetes mellitus occurs. Diabetes can be of two kinds:

  • Type 1 - In this case, the immune system destroys all the insulin producing cells, thereby, ceasing the production of insulin. As such, insulin injections are mandatory to maintain blood sugar levels.

  • Type 2 - In this case, the body does not respond well to the instructions of insulin and the sugar level in the body is not regulated. The body in turn produces a lot of insulin in a desperate attempt to improve blood sugar levels. The patients can turn the situation over by changing their food habits and lifestyle and taking certain medications.

For people taking insulin treatment, it is good to note that insulin can be of rapid acting type, short-acting type, long-acting type and intermediate-acting type.

Other Functions of Insulin

In addition to the regulation of glucose, insulin also plays a role in other areas of the body. It may be involved in all of the following functions to:

  • Modify the activity of enzymes and the resulting reactions in the body.
  • Manage synthesis of lipids by uptake into fat cells, which are converted to triglycerides.
  • Build muscle following sickness or injury via the transportation of amino acids to the muscle tissue, which is required to repair muscular damage and increase size and strength. It helps to regulate the uptake of amino acids, DNA replication and the synthesis of proteins.
  • Manage breakdown or protein and lipids due to changes in fat cells.
  • Uptake of amino acids and potassium into the cells that cannot take place in the absence of insulin.
  • Enhance learning and memory of the brain functions.
  • Manage excretion of sodium and fluid volume in the urine.

It is evident that insulin plays a number of essential roles in the body, including the management of sugar levels in the blood and many other areas.

In case you have a concern or query you can always consult an expert & get answers to your questions!

4239 people found this helpful

Know Everything About Insulin!

Dr. Anirban Biswas 93% (1258 ratings)
PGP In Diabetologist, Fellowship in Non-Invasive Cardiology, MD - Medicine, MBBS
Endocrinologist, Delhi
Know Everything About Insulin!

The first and the most important thing to be cleared is what exactly insulin is. Now we all are well accustomed with the fact that we get the energy to do what we do by eating the food we eat. So how exactly is all this energy generated? That is exactly what is going to be explained in the briefest way possible.

Most carbohydrates contain a type of sugar known as glucose. After we finish eating, the carbohydrates break down into smaller sugar molecules called glucose inside the digestive tract. Pancreas is a gland, which is located somewhere behind the stomach and is the source of all the endocrine functioning. This gland produces a hormone named Insulin. When the glucose molecules are released into our bloodstream, this insulin helps the cells throughout our body to soak up these simple sugar molecules and use them for providing the body with energy. Now that our base is clear, let’s move on to the importance of insulin in our body.

Why it is important?

Insulin helps our body to absorb glucose and provides the body with all the energy to do what it does. Another really important task that insulin does is balance the glucose levels in our blood. As soon as there is extra glucose in our blood-stream, insulin gives a signal in which the excess glucose is stored in the liver for future use, i.e, in situations when blood sugar drops and the body needs an extra energy boost.

Occurrence of diabetes

In a certain turn of events, when the body refuses to use the insulin properly or in worse cases, the body fails to produce enough insulin, diabetes mellitus occurs. Diabetes can be of two kinds:

  • Type 1 - In this case, the immune system destroys all the insulin producing cells, thereby, ceasing the production of insulin. As such, insulin injections are mandatory to maintain blood sugar levels.

  • Type 2 - In this case, the body does not respond well to the instructions of insulin and the sugar level in the body is not regulated. The body in turn produces a lot of insulin in a desperate attempt to improve blood sugar levels. The patients can turn the situation over by changing their food habits and lifestyle and taking certain medications.

For people taking insulin treatment, it is good to note that insulin can be of rapid acting type, short-acting type, long-acting type and intermediate-acting type. If you wish to discuss about any specific problem, you can consult a doctor and ask a free question.

3660 people found this helpful

Hi, I am diagnosed with SLE and been on treatment for 3 years now. I have been taking prednisolone, methotrexate, hydroxychloroquine, milzacipram etc for quite a long time. Because of these medicines I have put on tremendous amount of weight. Though I try to moderate my diet, cut down on salt and sugar, workout as much as I can in spite of pain, nothing seem to change. Can you suggest some way that may help me reduce.

Dr. P K Dhawan 90% (1378 ratings)
MSc Applied Biology, Diploma in Naturopathy
Ayurveda, Delhi
Hi, I am diagnosed with SLE and been on treatment for 3 years now. I have been taking prednisolone, methotrexate, hyd...
Do not say right DIAGNOISED SLE .otherwise with right treat one is supposed to get relief and cure .and you have developed Steroids hormones side effects .if you do not had DIABETES .lack of right amount of sugars will deficient insulin main cause of autoimmune diseases, including systemic lupus erythematosus .URGENT contact for right advice.
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After unprotected sex can I have methotrexate injection if I find that I may have ectopic pregnancy?

Dr. Samuel Rajkumar Pilli 90% (1198 ratings)
MD - Social & Preventive Medicine / Community Medicine
Epidemiologist, Hyderabad
After unprotected sex can I have methotrexate injection if I find that I may have ectopic pregnancy?
Ectopic pregnancy is a complication which is best treated by a gynecologist. The choice of treatment depends on the location and extent of the ectopic pregnancy.
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How to make taking methotrexate easier in Rheumatoid arthritis ?

Dr. Nilesh Nolkha 90% (421 ratings)
DM - Rheumatology, MD - General Medicine
Rheumatologist, Mumbai
How to make taking methotrexate easier in Rheumatoid arthritis ?

Methotrexate is one of the most commonly used drug in arthritis. It is the most important drug for rheumatoid arthritis (RA). However, methotrexate can cause severe nausea or sickness,  abdominal pain or even diarrhoea, in many patients. Many patients stop taking methotrexate due to this, which is not good, because taking methotrexate is very important in RA.

3 people found this helpful

I am 50, have Psoriasis (mainly scalp and back) and PSA. Should I take methotrexate with Arava or only Arava as I fear methotrexate will harm.

Dr. Shailender Dhawan 94% (3381 ratings)
Bachelor of Ayurveda, Medicine & Surgery (BAMS)
Ayurveda, Faridabad
I am 50, have Psoriasis (mainly scalp and back) and PSA. Should I take methotrexate with Arava or only Arava as I fea...
As you are 50 and suffering from psa and psoriasis. Psoriasis is genetic disorder triggered due to street and irregular life style. We are treating psoriasis using ayurvedic medicines. Psoriasis has three stages. First stage is when disease remain in skin and here are scaly patches. Second stage comes when there is pitting in nails and in last stage it enter the joints and there is pain in small joints. We can start ayurveda and wait for methotrexate. You should use 3 gms of haldi with milk and sit in sun for 15 minutes it helps. We are using external ayurvedic oil and ointment for application and internal blood purifying herbs which will solve your problem. We are capable of giving amazing results in very first month of treatment.
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Sir i have psoriasis from last 8 years and i taken so many medicines for this. Presently i am taking neotrexate 2.5mg tablets weekly once (morning and evening two tablets) my doctor left abroad but still i am continuing this tablets So i want to know whether i can continue this tablets or not because after taking this tablets my disease is in control but still i have some patches on my body

Dr. Sushruth Kamoji 90% (1933 ratings)
Diploma In Dermatology And Venerology And Leprosy (DDVL), Fellowship in Dermatosurgery
Dermatologist, Belgaum
Hi. Stop the tablets right now. Get your blood tests and liver function tests and see another dermatologist. The tablet can have bad effects on your liver.
2 people found this helpful
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After taking methotrexate I feel very weak for two days at least urine is Smokey colour.

Dr. G.R. Agrawal 97% (21418 ratings)
DHMS (Hons.)
Homeopath, Patna
After taking methotrexate I feel very weak for two days at least urine is Smokey colour.
Hello, it may be adverse effect of medication. Please, consult your physician, in this connection. Tk, care.
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Why Methotrexate injection used for abortion with misoprostol tablets. Does this combination will effect on future fertility.

Dr. Sushma Baxi 84% (366 ratings)
MD, MBBS
Gynaecologist, Vadodara
Why Methotrexate injection used for abortion with misoprostol tablets. Does this combination will effect on future fe...
It is mifepristone given with misoprost for termination of pregnancy. Very rarely methotrexate is given but the reasons are specific. If given it acts for a week or two so it doesn’t have effect on future fertility
1 person found this helpful
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Is there any Insulin tablet or capsule that can be taken orally in stead of insulin injection?

Vaidya Visharad
Sexologist, Narnaul
Dear, According to Ayurveda There are 20 forms of Diabetes : 4 are due to Vata, 6 result from Pitta, and 10 are caused by Kapha. But Diabetes (MADHUMEHA) is.Mainly kapha dosha disease. Poorly managed diabetes can lead to a host of long-term complications like :- Heart attacks, Strokes, Blindness, Nerve damage, Amputation of Limb. Impotency in men.Visit us at www.Malhotraayurveda.Com