Get Dettol Kit worth Rs. 130 for just Rs. 4
Common Specialities
Common Issues
Common Treatments

Megalis 20 MG Tablet

Manufacturer: Macleods Pharmaceuticals Pvt.Ltd
Medicine composition: Tadalafil
Prescription vs.OTC: Prescription by Doctor not required
Last Updated: May 20, 2019

Megalis 20 MG Tablet functions by relaxing the muscles that are present in and around blood vessels, which helps with increasing blood flow. Due to this reason, these tablets are used to treat erectile dysfunction, and benign prostatic hypertrophy, which is an enlarged prostate. As it helps increasing blood flow, it is also used to treat pulmonary hypertension, which is also known as high blood pressure. This is not an OTC tablet, which means that you require a doctor’s prescription to take it and to buy it.

Megalis tablets can cause a few minor side effects. These include belching, heartburn, indigestion, pain in the neck, pain in the stomach, and even fever. Other side effects include confusion, fainting, breathing problems, nausea, and weakness, sweating and vomiting. However, these side effects are quite rare. They generally go away on their own. However, one side effect that requires medical attention is you end up with an erection that lasts for over 4 hours. This is because it can cause damage to your penis and the way it functions. Furthermore, if your erection feels painful, you consult seek medical care immediately.

Erectile Dysfuntion

benign prostatic hyperplasia

Pulmonary arterial hypertension

In addition to its intended effect, Megalis 20 MG Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.


Moderate Less Common


Moderate Less Common


Moderate Less Common


Moderate Less Common

Allergic skin reaction

Moderate Less Common

Difficulty in breathing

Moderate Less Common

Stomach pain

Moderate Less Common

How long is the duration of effect?

The duration of effect lasts for a few hours.

What is the onset of action?

The onset of action occurs anytime between 30 minutes – 1 hour after taking it.

Are there any pregnancy warnings?

No, Megalis 20 MG Tablet is not safe for pregnant women as it can affect the foetus.

Is it habit forming?

There are no habit forming tendencies reported with Megalis 20 MG Tablet.

Are there any breast-feeding warnings?

No, this medication is not safe for breastfeeding women as it can affect the baby.

Is It safe with alcohol?

Megalis 20 MG Tablet is not safe with alcohol. If you experience certain symptoms such as stomach bleeding or ulcers, then you must speak to your doctor immediately.

Is it safe to drive while on this medicine?

As some of the side effects of this medication include confusion and weakness, it is not advisable to drive after taking the pill.

Does this affect kidney function?

Patients who have impaired kidney function should not take this pill as it can lead to more kidney problems.

Does this affect liver function?

Patients who have impaired liver function should not take this pill as it can lead to more liver problems, including liver failure.

Below is the list of medicines, which have the same composition, strength and form as Megalis 20 MG Tablet , and hence can be used as its substitute.
Abbott Healthcare Pvt. Ltd
Lupin Ltd
Ajanta Pharma Ltd
Ajanta Pharma Ltd
Zydus Cadila

Are there any missed dose instructions?

If you miss a dose, you should take one as soon as you remember that you’ve missed the dose.

Are there any overdose instructions?

If you have overdosed on the medication, you must consult your doctor immediately. Certain signs of overdose include fast heartbeat, weakness, fainting and confusion.

Megalis 20 MG Tablet relaxes the smooth muscles by inhibiting Phosphodiesterase type-5. This results in the increase of cyclic guanosine monophosphate (cGMP) which relaxes the smooth muscles and increases the flow of blood.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

Interaction with Disease



It can have negative interactions with certain diseases. These include asthma, impaired kidney function, and gastro-intestinal toxicity.

Interaction with Medicine



These tablets can have adverse interactions with certain medications. These include nitroglycerin, phenytoin, ketoconazole, amlodipine, carbamazepine, and cimetidine.

Ques: What is Megalis 20 mg tablet?

Ans: Megalis 20 mg tablet is a medication having Tadalafil as an active ingredient present in it. It perform its action by increasing blood flow in the penis by relaxing and widening the blood vessel of that part of body. It is used for Increase prostate gland in male and Increased blood pressure in lungs. Apart from this, it also helps in erectile dysfunction by relaxing the muscles in penile blood vessels.

Ques: What are the side effects of Megalis 20 mg tablet?


Megalis 20 mg tablet is a medication which is used for the treatment, control, and prevention of the below mentioned conditions such as:

  1. Enlarged prostate gland in male
  2. Increased blood pressure in lungs
  3. Erectile dysfunction.
  4. Pulmonary arterial hypertension

Ques: What are the side effects of Megalis 20 mg tablet?


Megalis 20 mg tablet is a medication which has some known side effects. These side effects may or may not occur always and some of them are rare and severe. If you experience any of the below mentioned symptoms, contact your doctor immediately. List of some commonly reported side effects of Megalis 20 mg tablet:

  1. Facial swelling
  2. Headache
  3. Muscle pain
  4. Upper abdominal pain
  5. Rash
  6. Urge to vomit
  7. Bleeding from nose
  8. Chest pain
  9. Cephalalgia
  10. Flushing
  11. Penile erectile problems
  12. Fainting
  13. Blurred vision
  14. Difficulty in swallowing
  15. Back pain
  16. Increased uterine bleeding
  17. Sore throat
  18. Pain in the extremities
  19. Allergic rejection
  20. Nasal blockage
  21. Indigestion
  22. Vomiting
  23. Frequent persistent heartburn
  24. Flu-like symptoms
  25. Flow of bitter fluid into mouth
  26. Blurred vision

Ques: Can I take Megalis with prednisone?

Ans: Megalis 20 mg tablet is a medicine, when taken with prednisone, it may cause low blood pressure. Consult your doctor for the adequate dosage or an alternative medication of choice that may be required when the two medicines are to be used together. It is a prescribed medication.

Ques: How long do I need to use megalis 20 mg tablet before I see improvement of my conditions?

Ans: This medication should be consumed, till the complete eradication of disease. Thus it is advised to use, till the time directed by your doctor and moreover taking this medication longer than it was prescribed, can also cause inadequate effect on the patient. So please consult your doctor.

Ques: At what frequency do I need to use megalis 20 mg tablet ?

Ans: This medication is generally used once in 3 days, as the time interval upto which this medication has an impact, is around 36 to 40 hours, but it is not the standard frequency for using this medication. It is advised to consult your doctor for the dosage, as the frequency also depends on the patient's condition.

Ques: Should I use megalis 20 mg tablet empty stomach, before food or after food?

Ans: This medication is commonly taken orally from mouth and the action of salts involved in this medication, do not depend on using it pre-meal or post-meal. It is advised to consult a doctor before use and take it at a fixed time in a the day.

Ques: What are the instructions for storage and disposal of megalis 20 mg tablet?

Ans: This medication contains salts, which are suitable to store at room temperature and keeping this medication above or below that, can cause inadequate effect. Protect it from moisture and light. Keep this medication away, from the reach of children. It is advised to dispose the expired or unused medication, for avoiding its inadequate effect.

Tadalafil- Drug Information Portal [Internet]. 2019 [Cited 23 April 2019]. Available from:

Tadalafil:Uses, Dosage, SE & Get Cialis Online- Drugs Bank [Internet]. 2018 [Cited 25 April 2019]. Available from:

Adcirca- EMC [Internet]. 2017 [Cited 24 April 2019]. Available from:
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

Popular Health Tips

Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MD-Pharmacology, MBBS
Table of Content
About Megalis 20 MG Tablet
What are the uses of Megalis 20 MG Tablet
What are the contraindications of Megalis 20 MG Tablet ?
What are the side effects of Megalis 20 MG Tablet ?
Key highlights of Megalis 20 MG Tablet
What are the substitutes for Megalis 20 MG Tablet ?
What are the dosage instructions?
How does medicine works?
What are the interactions of Megalis 20 MG Tablet ?
Megalis 20 MG Tablet Frequently Asked Questions (FAQs):