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Hi, My daughter was given 1st vaccine on 25/01/2019 and 2nd vaccine date is on 22/02/2019 is it right.

Hi, My daughter was given 1st vaccine on 25/01/2019 and 2nd vaccine date is on 22/02/2019 is it right.
4-week minimum interval between doses of the same live vaccine is advised. Different vaccines can be given even on same days.
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Is There a Connection Between Vaccines and Autism?

Is There a Connection Between Vaccines and Autism?

No, there is no connection between vaccines and autism.

Autism is a condition that affects the brain and makes communicating and interacting with other people more difficult. The cause (s) of autism — also known as autism spectrum disorder (asd) or pervasive developmental disorder (pdd) — is unknown. However, genetics, differences in brain anatomy, and toxic substances in the environment are thought to contribute to children developing the condition.

So how did the idea that vaccines play a role get started? Much of the blame lies with a study published in 1998 that suggested that the mmr (measles-mumps-rubella) vaccine, or infection with the naturally occurring measles virus itself, might cause autism. Since then, numerous scientific studies have shown that there is no link between vaccines — or any of their ingredients — and autism. And the research used in that study was found to be false, the doctor who wrote it lost his medical license, and the medical journal that published it retracted the paper (this means that they believe it never should have been published).

Even with the overwhelming evidence that vaccines are safe and effective, some parents still decide not to have their children vaccinated or to delay vaccinations. But this is extremely risky because vaccine-preventable diseases like measles are still very much around. So if an unvaccinated child gets one of these preventable diseases, other people around that child could get very sick.

Sometimes, kids can have a reaction to a vaccine like a mild fever or rash. But it's clear that the risk of serious reactions to the mmr and other recommended vaccines is small compared with the health risks associated with the often-serious diseases they prevent.

If you have concerns about any vaccine recommended for your child, talk to your doctor. Ask about the benefits and risks of each vaccine and why they're so important for safeguarding your child's health.

Why Vaccination Is Required Against Chicken Pox?

Why Vaccination Is Required Against Chicken Pox?

Chickenpox or varicella is a type of viral infection that causes itchy rashes accompanied by tiny fluid-filled blisters. It is highly communicable to those who have not experienced this disease earlier or have not been immunized against it through vaccination

The vaccine against chickenpox is a shot protecting anyone, who has already contracted the disease. It is known as the varicella vaccine since chicken pox is triggered by the virus called varicella-zoster. The vaccine is prepared from a living but a weakened virus.

Why would you require a chicken pox virus?

  1. The risk behind the condition aggravating into something life threatening is high among adults, infants and people possessing a weak immunity system as they are prone to developing serious complications as well. There is no way you can predict who would be the next prey.
  2. The illness is extremely contagious and can get transmitted either through air while coughing or sneezing or by direct contact especially with the fluid present in the chicken pox blisters. For this reason, you need to stay segregated until and unless all your blisters have dried up or crusted over. The illness may induce itchy rashes all over your body along with fussiness, cough and headaches.
  3. The vaccine is recommended for all adults and adolescents who have not been infected by chicken pox ever earlier. A vaccine called MMRV offers a combined protection against varicella, rubella, mumps and measles.
  4. The vaccine has to be administered in two shots. However the medicines are not devoid of mild side effects,for instance, swelling in the region where you have been injected alongside mild rashes.

Who should not opt for the vaccine?

  1. Pregnant women since the effect of the vaccine on your fetus is yet to be unraveled
  2. People who are allergic to neomycin and gelatin ( a gelatin-free varicella vaccine is actually available)
  3. People suffering from diseases caused due to a weak immunity system or taking high dosage of steroids
  4. Cancer patients who have to be treated with chemotherapy, drugs and X-rays
  5. People who have had a blood transfusion in about five months before receiving the shot.
3497 people found this helpful

Inactivated Influenza Vaccine During Pregnancy!

Inactivated Influenza Vaccine During Pregnancy!

During pregnancy, flu (influenza) can impose serious health implications for both the mother and the child. Due to pregnancy, the risk of developing complications like pneumonia are very high, which can pose as a problem during childbirth. Miscarriage, low birth weight, premature birth are some of the major issues, which might develop if the mother has suffered from flu during her pregnancy. Although flu vaccination during pregnancy has certain risks, it has been observed that in most cases the benefits of inactivated influenza vaccine outweigh the risks. However, Live attenuated influenza vaccine is not recommended at all during pregnancy.

Recommendations across the world suggest that prevention of influenza by administration of inactivated influenza vaccine is the best intervention in pregnancy. The vaccine for Flushould be administered before the onset of flu season. RANZCOG, NHS UK, RCOG, FOGSI recommends inactivated flu vaccine for all the pregnant women unless there are any contraindications. 

Taking inactivated influenza vaccine can be beneficial in multiple ways:

  1. Prevents maternal complications: During pregnancy, the heart and lungs go through extra stress. Pregnancy can also severely impact your immune system. Opting for a inactivated flu vaccine can decrease significantly, the chance of falling severely ill due to flu.
  2. Prevents pregnancy problems due to flu: Getting infected by flu during pregnancy can increase the chance of miscarriage during childbirth. Administering inactivated flu shots can prevent miscarriage as well as premature birth and low birth weight.
  3. Protects the baby after birth: Infants have a huge risk of getting infected with flu after birth. But as vaccines cannot be administered to them until they are 6 months old, it is the best recourse to opt for inactivated flu shots during pregnancy as the antibodies pass onto the child from the mother via placenta. The child can hence be protected from such diseases.

Some concerns
Often, one fear about the vaccine, is the development of Gullain Barre syndrome. This is very rare and the risk of GBS are higher following influenza like illness. Also, if the patient is allergic to eggs they are advised to consult a physician. Flu vaccines have traces of egg protein in it. Certain precautions are taken after studying the patient's medical history. The doctor may keep the patient under observation. Or in certain instances the physician might suggest alternative flu vaccine, which do not contain egg protein. Physicians decide it after studying any prior allergic reaction.

As per  the WHO SAGE position paper, from 1990 to 2009 the vaccine adverse event reporting system database in USA reported only 20 serious adverse events following administration of trivalent influenza vaccine to an estimated 11.8 million pregnant women.

In case you have a concern or query you can always consult an expert & get answers to your questions!

 

2273 people found this helpful

Flu Shot - Everything You Need To Know About The Vaccination!

Flu Shot - Everything You Need To Know About The Vaccination!

Flu is caused by a virus known as influenza and is a common respiratory disease. It is typically caused from the month of October to May. Some of the common symptoms include fatigue, runny nose, fever, cough, muscle ache, sore throat, body ache, etc. 

The flu vaccination helps to protect from influenza. The effect generally lasts for a year. It is recommended that an individual takes this vaccination once in a year since the strain of the virus keeps changing every year. Flu vaccine comprises of an egg-based technology.

Who Can catch flu?
Anyone can get a flu vaccination. Children above the age of 6 months or more are eligible to get a flu vaccination. In addition, the person who has a severe outbreak of allergic reaction due to the flu vaccination should also stay away from this. 

Pregnant women can also get this vaccination without any worry about the baby. They not only safeguard the mother, but protect the child from influenza too. Adults who are more than 65 years old can take this vaccination without worrying. Patients with an acute allergy should consult their doctors before taking a flu shot.

Are there any side effects?
Although most people do not feel a thing after the flu shot, some might experience mild symptoms, such as redness of the area where the vaccine has been injected, mild body aches, soreness, redness and fever. Other serious side effects include allergic reaction resulting in soreness and very high fever. A doctor or healthcare personnel should be immediately contacted in such an instance. 

Can flu shot cause flu?
This is totally a myth. A flu vaccine doesn’t result in the flu. The virus content of the flu vaccine doesn’t contain any live virus that can potentially trigger an outbreak of flu in the body. They are noninfectious in every sense of the word. It takes a couple of weeks for the flu vaccine to build immunity in the body. A person might get affected during this time if he comes in contact with an infected person.

Confusing flu with similar symptoms:
Common symptoms of flu such as nausea, vomiting, sneezing, body ache and fever can be symptoms of an entirely different disease such as diarrhoea. Until the tests are conducted and the doctor gives an assured verdict of flu, it is unwise to take a flu vaccination based on gut feel and mere speculation. 

When is an ideal time to take flu vaccine?
There is no right or wrong time of taking a flu shot. It is seriously infectious and can catch hold of a person at any time. The right time to take a flu shot is now. It is readily available over the counter and can be injected at any time of the year.

5167 people found this helpful

Inactivated Influenza Vaccine During Pregnancy

Inactivated Influenza Vaccine During Pregnancy

During pregnancy, flu (influenza) can impose serious health implications for both the mother and the child. Due to pregnancy, the risk of developing complications like pneumonia are very high, which can pose as a problem during childbirth. Miscarriage, low birth weight, premature birth are some of the major issues, which might develop if the mother has suffered from flu during her pregnancy. Although flu vaccination during pregnancy has certain risks, it has been observed that in most cases the benefits of inactivated influenza vaccine outweigh the risks. However, Live attenuated influenza vaccine is not recommended at all during pregnancy.

Recommendations across the world suggest that prevention of influenza by administration of inactivated influenza vaccine is the best intervention in pregnancy. The vaccine for Flu should be administered before the onset of flu season. RANZCOG, NHS UK, RCOG, FOGSI recommends inactivated flu vaccine for all the pregnant women unless there are any contraindications. 

Taking inactivated influenza vaccine can be beneficial in multiple ways:

  1. Prevents maternal complications: During pregnancy, the heart and lungs go through extra stress. Pregnancy can also severely impact your immune system. Opting for a inactivated flu vaccine can decrease significantly, the chance of falling severely ill due to flu.
  2. Prevents pregnancy problems due to flu: Getting infected by flu during pregnancy can increase the chance of miscarriage during childbirth. Administering inactivated flu shots can prevent miscarriage as well as premature birth and low birth weight.
  3. Protects the baby after birth: Infants have a huge risk of getting infected with flu after birth. But as vaccines cannot be administered to them until they are 6 months old, it is the best recourse to opt for inactivated flu shots during pregnancy as the antibodies pass onto the child from the mother via placenta. The child can hence be protected from such diseases.

Some concerns
Often, one fear about the vaccine, is the development of Gullain Barre syndrome. This is very rare and the risk of GBS are higher following influenza like illness. Also, if the patient is allergic to eggs they are advised to consult a physician. Flu vaccines have traces of egg protein in it. Certain precautions are taken after studying the patient's medical history. The doctor may keep the patient under observation. Or in certain instances the physician might suggest alternative flu vaccine, which do not contain egg protein. Physicians decide it after studying any prior allergic reaction.

As per  the WHO SAGE position paper, from 1990 to 2009 the vaccine adverse event reporting system database in USA reported only 20 serious adverse events following administration of trivalent influenza vaccine to an estimated 11.8 million pregnant women.

3517 people found this helpful

First Vaccine Again Dengue

First Vaccine Again Dengue

Dengvaxia - First vaccine against dengue:

Dengvaxia is a vaccine used to help protect adult or children against dengue disease caused by dengue virus serotypes 1, 2, 3 and 4. Dengvaxia is given to adults, adolescents and children 9 through 45 years of age living in endemic areas.

 

Read more:-

Dengue symptoms and what to do if you think you have denguedengue fever - remedies using papaya leaf juice

 

Full prescribing info - dengvaxia

Contents

Dengue tetravalent vaccine (live, attenuated).

Indications / uses

Dengvaxia is a vaccine used to help protect adult or children against dengue disease caused by dengue virus serotypes 1, 2, 3 and 4. Dengvaxia is given to adults, adolescents and children 9 through 45 years of age living in endemic areas.

Dosage / direction for use

The patient will receive 3 injections of 0.5 ml each at 6-month intervals.

The first injection will occur at the chosen or scheduled date; the second injection, 6 months after the first injection; and the third injection, 6 months after the second injection. Dengvaxia should be used according to the local vaccination schedule.

If the patient forgot an injection of dengvaxia: if the patient missed a scheduled injection, the physician will decide when to give the missed injection.

It is important that the patient follows the instructions of the physician, pharmacist or nurse regarding return visits for the follow-up injection. If the patient forgets or is not able to go back to the physician, pharmacist or nurse at the scheduled time, ask the physician, pharmacist or nurse for advice.

Administration: dengvaxia is given by the physician or nurse as an injection underneath the skin (subcutaneous route) in the upper arm.

Contraindications

Do not use dengvaxia if the patient is allergic (hypertensive) to the active substances or any of the other ingredients of dengvaxia listed in description (see description); has developed an allergic reaction after prior administration of dengvaxia. Signs of an allergic reaction may include an itchy rash, shortness of breath and swelling of the face and tongue; is suffering from a disease with mild to high fever or acute disease. In this case, the physician will postpone the administration of dengvaxia until the patient has recovered; has a weakened immune system, for example due to a genetic defect, hiv infection or therapies that affect the immune system (for example, high-dose corticosteroids or chemotherapy); is pregnant; is breastfeeding.

Use in pregnancy lactation: Dengvaxia must not be given to pregnant or breastfeeding women.

If the patient is of child-bearing stage, the patient should take the necessary precautions to avoid pregnancy for 1 month following administration of dengvaxia; is pregnant or breastfeeding, the patient thinks may be pregnant or is planning to have a baby, ask the physician, pharmacist or nurse for advice before receiving dengvaxia.

Special precautions

Inform the physician, pharmacist or nurse before receiving dengvaxia if the patient is taking an immunosuppressive treatment (prednisone or equivalent to 20 mg or 2 mg/kg for 2 weeks or more). The physician will postpone administration of dengvaxia until 4 weeks after the treatment is discontinued; has experienced any health problems after prior administration of any vaccines. The physician will carefully consider the risks and benefits of vaccination.

As with all vaccines, dengvaxia may not protect 100% of persons who have been vaccinated. Vaccination with dengvaxia is not a substitute for protection against mosquito bites. The patient should take appropriate precautions to prevent mosquito bites, including the use of repellents, adequate clothing, and mosquito nets.

Fainting, sometimes accompanied by falling, can occur (mostly in adolescents) following, or even before, any injection with a needle. Therefore inform the physician, pharmacist or nurse if the patient fainted with a prior injection.

Adults above 45 years of age: adults above 45 years of age should not receive the vaccine.

Driving and using machines: no data are available on the effects of dengvaxia on the ability to drive or use machines.

Use in children: Children less than 9 years of age should not receive the vaccine.

 

Side effects:

Like all medicines, dengvaxia can cause side effects, although not all patients get them.

Serious allergic reactions: If any of these symptoms occur after leaving the place where the patient received an injection, consult a physician immediately: difficulty in breathing, blueness of the tongue or lips, a rash, swelling of the face or throat, low blood pressure causing dizziness or collapse.

When these signs and symptoms occur they usually develop quickly after the injection is given and while the patient is still in clinic or physician's surgery.

Serious allergic reactions are very rare (may affect up to 1 in 10,000 people), after receiving any vaccine.

Other side effects: The following side effects were reported during clinical studies in children, adolescents and adults (from 9 to and including 60 years of age). Most of the reported side effects occurred within 3 days after the injection of the vaccine: very common (may affect more than 1 user in 10): headache, muscle pain (myalgia), generally feeling unwell (malaise), feeling of weakness (asthenia), injection site pain, fever.

Common (may affect up to 1 user in 10): Injection site reactions: redness (erythema), bruising (hematoma), swelling, and itching (pruritus).

Uncommon (may affect up to 1 user in 100): Infections of the upper respiratory tract, dizziness, sore throat (oropharyngeal pain), cough, runny nose (rhinorrhea), nausea, skin eruption (rash), neck pain, hardening of skin at the injection site (injection site induration).

Additional side effects in adults (from 18 to and including 60 years of age): Uncommon (may affect up to 1 user in 100): swollen glands (lymphadenopathy), migraine, joint pain (arthralgia), flu-like symptoms (influenza-like illness).

Additional side effects in children and adolescents (from 9 to and including 17 years of age: Uncommon (may affect up to 1 user in 100), Itchy rash (urticaria).

Reporting of side effects or any suspected adverse event: If the patient experiences any side effects after vaccination, advised to seek immediate medical attention.

By reporting side effects, it can help provide more information on the safety of the vaccine.

 

Interactions:

Using other medicines and dengvaxia: Dengvaxia may not have an optimal effect if it used at the same time as medicines that suppress the immune system such as corticosteroids or chemotherapy.

Inform the physician, pharmacist or nurse if the patient is taking or has recently taken any other vaccines or any other medicines, including medicines obtained without a prescription.

 

Caution for usage:

Before administering any biological, the person responsible for administration must take all precautions to prevent allergic or other reactions. As with all injectable vaccines, appropriate medical treatment and supervision must always be readily available in the event of an anaphylactic reaction following the administration of dengvaxia.

Epinephrine (1:1000) and other appropriate agents used to control immediate allergic reactions must be available to treat unexpected events such as anaphylaxis.

Dengvaxia must not be mixed with other medicinal products in the same syringe.

Dengvaxia must not be administered by intravascular injection under any circumstances.

Syncope (fainting) can occur following, or even before, any vaccination as a psychogenic response to injection with a needle. Procedures should be in place to prevent injury from falling and to manage syncopal reactions.

Separate syringes and needles, separate injection sites and preferably separate limbs must be used if any other vaccine (s) or medicinal product (s) is/are concomitantly administered.

Dengvaxia is reconstituted by transferring all the solvent (0.4% sodium chloride solution) provided in the blue-labeled pre-filled syringe into the vial of freeze dried powder with a yellowish green flip off cap. The pre-filled syringe is fitted with a sterile needle for this transfer. The vial is then gently swirled. After complete dissolution, a 0.5 ml dose of reconstituted suspension is withdrawn into the same syringe. For injection, the syringe should be fitted with the new sterile needle.

The suspension should be visually inspected prior to administration. After reconstitution, dengvaxia is clear, colorless liquid with the possible presence of white to translucent particles (of endogenous nature).

After reconstitution with the solvent provided, dengvaxia must be used immediately.

Any unused dengvaxia or waste material should be disposed of, preferably by heat inactivation or incineration, in accordance with local regulations.

Do not throw away any medicines via wastewater or household waste. Ask a pharmacist on how to throw away medicines that no longer use. These measures will help to protect the environment.

 

Storage

Store in a refrigerator (2°c-8°c). Do not freeze. Keep the vaccine in the outer carton in order to protect it from light.

 

Description

After reconstitution, one dose (0.5 ml) contains 4.5-6.0 log10 ccid50* of each serotype of the cyd dengue virus** (1, 2, 3 and 4).

* ccid50: 50% cell culture infectious dose.

** produced in serum-free vero cells by recombinant dna technology.

The powder is a white, homogenous, freeze-dried powder with possible retraction at the base, and may form a ring-shaped cake.

The solvent (0.4% sodium chloride solution) is a clear, colorless liquid.

After reconstitution with the solvent provided, dengvaxia is a clear, colorless liquid with the possible presence of white to translucent particles.

Excipients/inactive ingredients: essential amino acids including l-phenylalanine, non-essential amino acids, l-arginine hydrochloride, sucrose, d-trehalose dihydrate, d-sorbitol, trometamol, urea, sodium chloride, water for injections.

 

Mechanism of action:

Dengvaxia contains dengue virus serotypes 1, 2, 3 and 4 that have been weakened. Dengvaxia works by stimulating the body's natural defenses (immune system), which produces its own protection (antibodies) against the viruses that cause dengue disease.

Dengue is a viral infection transmitted to humans through the bite of an infected aedes mosquito. Dengue is not transmitted directly from person-to-person. Nevertheless the virus which replicates in an infected individual can be transmitted to other humans through mosquito bites for 4-5 days (maximum 12 days) after the first symptoms appear.

Dengue disease results in a wide range of symptoms including fever, headache, pain behind the eyes, muscle and joint pain, nausea, vomiting, swollen glands or skin rash. Symptoms usually last for 2-7 days. Dengue disease can also be asymptomatic.

However, occasionally dengue can be severe and potentially lead to hospitalization and in rare cases to death. Severe dengue is characterized by high fever and any of the following symptoms: severe abdominal pain, persistent vomiting, rapid breathing, severe bleeding, bleeding in stomach, bleeding gums, fatigue, restlessness, coma, seizure and organ failure.

Source:- http://www.mims.com/philippines/drug/info/dengvaxia

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