Get Dettol Kit worth Rs. 130 for just Rs. 4
Common Specialities
{{speciality.keyWord}}
Common Issues
{{issue.keyWord}}
Common Treatments
{{treatment.keyWord}}

Overview

Lignox Adr 2% Injection

Manufacturer: Indoco Remedies Ltd
Medicine composition: Lidocaine
Prescription vs.OTC: Prescription by Doctor not required

Lignox Adr 2% Injection is a local anesthetic. It is used topically on the skin to reduce itchiness and skin conditions such as insect bites, eczema and burns. It is also used to cure hemorrhoids and problems of the genital/anal regions. This medication functions by reducing pain, redness and swelling. The viscous variant is used for dental treatment.

On using Lignox Adr 2% Injection you may experience certain side effects such as a burning or stinging sensation, dizziness, drowsiness, changing body temperatures, blurred vision or a pounding/ringing in your ears. Severe reactions include depression, numbness and vomiting. Should your reactions continue and become worse over time contact your doctor right away.

Before using Lignox Adr 2% Injection inform your doctor if: you are allergic to any medicine, food, substances or ingredients contained within Lignox Adr 2% Injection, you have diabetes, liver/ stomach problems and infections.

Take the dosage recommended by your doctor for your condition. This topical medication comes as a gel, spray, cream, lotion and skin patch. Apply on the affected area of the skin after cleaning and drying it well. It is usually recommended to use about 2-3 times a day.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Anesthesiologist before using this medicine.

piles
, local anaesthesia and
In addition to its intended effect, Lignox Adr 2% Injection may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Abnormal sensation
Application site swelling
Skin redness.
Is It safe with alcohol?
No interaction found
Are there any pregnancy warnings?
Xynova endo 200mg lozenges is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
Are there any breast-feeding warnings?
Xynova endo 200mg lozenges is probably safe to use during breastfeeding. Please consult your doctor.
Is it safe to drive while on this medicine?
There is no interaction between driving and consuming this drug. So dose alteration is not needed.
Does this affect kidney function?
There is no data available. Please consult doctor before consuming the drug.
Does this affect liver function?
There is no data available. Please consult doctor before consuming the drug.
Below is the list of medicines, which have the same composition, strength and form as Lignox Adr 2% Injection , and hence can be used as its substitute.
Themis Medicare Ltd
Biochem Pharmaceutical Industries
Unichem Laboratories Ltd
Neon Laboratories Ltd
Wockhardt Ltd
Vhb Life Sciences Inc
Indoco Remedies Ltd
Mankind Pharma Ltd
Ind Swift Laboratories Ltd
Themis Medicare Ltd
Astra Zeneca
Astra Zeneca
Neon Laboratories Ltd
Samarth Life Sciences Pvt Ltd
Lignox Adr 2% Injection is a local anaesthetic and antiarrhythmic that works by stabilising the neuronal membrane by blocking the voltage gated sodium channels. This inhibits depolarisation of the postsynaptic nerve that prevents transmission of pain signals.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

What should a women do when she is caused of pain and vagina pain. After sexual intercourse.

DM- Obstetrics, Gynaecology & Diseases of Infancy
Gynaecologist,
She has to be examined to find the reason. On temporary basis apply lignox jelly abt 15 mins before sex & wipe off just before sex. If dryness in vagina can use ky jelly locally.

Hello doctor, my baby is 7 weeks old. She has been having constipation lately and has not passed any motion for the last 4 days. Her doctor prescribed neopeptine drops today but even then she has not passed any motion as of now. She is totally on mothers feed and her appetite is also normal. But motions are just not passing. Please advise.

DHMS (Diploma in Homeopathic Medicine and Surgery), FWT (W.B)
Homeopath, 24 Parganas
Hello doctor, my baby is 7 weeks old. She has been having constipation lately and has not passed any motion for the l...
Hi Lybrate user, as adr I prescribed of your child to intake water &bathing properly you can give her homoeopathic medecine for bowel China 6 2 drops mixed with half cup water one teaspoonful every after one hour 2 times, if need give 2 times morning and at night, thanks, take care.

Sir I am suffering from pain last 3 year in my right shoulder t moderate to legs I have done every test like ct scan x-ray inxray I have problem of spondylitis by CT scan and MRI didn't show that I consult many Dr. but no relief ADr prescribe antidepressant pill but no relief after all I did physiotherapy but no relief respected sir now what can I do.

MS Ayurved, Bachelor of Ayurveda, Medicine & Surgery (BAMS)
Ayurveda, Junagadh
Sir I am suffering from pain last 3 year in my right shoulder t moderate to legs I have done every test like ct scan ...
Dear Lybrate User, As per your complains & investigations it seems like spondylitis may be due to Osteoarthritis OR Rheumatism OR degenerative joint changes. For conformation of this you need to under go some investigations. Initially avoid yogurt, curt, excessive spicy & slaty foods, fast food & junk food, cold water/milk, cold drinks, avoid sprouted pulses like mung-chana etc. Don't sit directly at floor. Have hot fomentation on Joints & painful area, do small exercises of joints, Took proper sun bath, fruits & vegetables except all beans & pulses. For sure result you need ayurvedic panchkarma treatment. For more discussion consult me personally.

Dear sir or madam how to increasing my weight gain at short time I mean just one month what I eating a food and what I doing exiers .pls suggested meee.

M.sc dietitics and food service management, Diabetes educator
Dietitian/Nutritionist, Bhopal
Dear sir or madam how to increasing my weight gain at short time I mean just one month what I eating a food and what ...
Hello, aDr more protein in your diet like soyabean, pulses, milk and milk products; egg. Do some basic workout every day. You can try whey protein powder after workout. You should take high calories food that increase your muscle mass and induce growth in bones. Peanut butter is another yummy remedy for gain weight. Take small and frequent meals. Avoid junk food and processed food. No drinks before and with meals. You can consult me privately online on Lybrate I will give you diet chart.
1 person found this helpful

5 month ago I deliver a baby. After one month of delivery I have started anal fissure pain. I have try cream gel ointments but with that not any relief. Now it's very pain full at the time of potty. Please suggest me what should I do?

Fellowship in Minimal Access Surgery, FACRSI (Colo-Rectal Surgery), Ph. D - Gastrointestinal Surgery, FAIS, DNB (General Surgery), MNAMS (Membership of the National Academy) (General Surgery) , MBBS
Gastroenterologist, Bangalore
5 month ago I deliver a baby. After one month of delivery I have started anal fissure pain. I have try cream gel oint...
Get a horizontal bucket, put Luke warm water and sit in that for 15 min. Three times a day (called seitz bath). Apply ditigesic ointment in and out side of motion area for 3-4 times a day, after passing stool. Take syp. Cremaffin plus 30 ml 1-0-1 for 5-6 days (adjust the doses in case of loose stool). Take tab. Calpol 650 mg 1-1-1 for pain. Apply Lignox 2% gelly inside motion area only before passing stool, this will decrease pain. Regards,
6 people found this helpful

Popular Health Tips

Dengue Vaxia

MBBS,CCA,DCA,AASECT,FPA,AAD,F.H.R.SM.I.M.S
General Physician, Bangalore
Dengue Vaxia

Dengvaxia - first vaccine against dengue

Dengvaxia is a vaccine used to help protect adult or children against dengue disease caused by dengue virus serotypes 1, 2, 3 and 4. Dengvaxia is given to adults, adolescents and children 9 through 45 years of age living in endemic areas.

Read more:

Dengue symptoms and what to do if you think you have denguedengue fever - remedies using papaya leaf juice

Full prescribing info - dengvaxia

Contents

Dengue tetravalent vaccine (live, attenuated).

Indications / uses

Dengvaxia is a vaccine used to help protect adult or children against dengue disease caused by dengue virus serotypes 1, 2, 3 and 4. Dengvaxia is given to adults, adolescents and children 9 through 45 years of age living in endemic areas.

Dosage / direction for use

The patient will receive 3 injections of 0.5 ml each at 6-month intervals.

The first injection will occur at the chosen or scheduled date; the second injection, 6 months after the first injection; and the third injection, 6 months after the second injection. Dengvaxia should be used according to the local vaccination schedule.

If the patient forgot an injection of dengvaxia: if the patient missed a scheduled injection, the physician will decide when to give the missed injection.

It is important that the patient follows the instructions of the physician, pharmacist or nurse regarding return visits for the follow-up injection. If the patient forgets or is not able to go back to the physician, pharmacist or nurse at the scheduled time, ask the physician, pharmacist or nurse for advice.

Administration: dengvaxia is given by the physician or nurse as an injection underneath the skin (subcutaneous route) in the upper arm.

Contraindications

Do not use dengvaxia if the patient is allergic (hypertensive) to the active substances or any of the other ingredients of dengvaxia listed in description (see description); has developed an allergic reaction after prior administration of dengvaxia. Signs of an allergic reaction may include an itchy rash, shortness of breath and swelling of the face and tongue; is suffering from a disease with mild to high fever or acute disease. In this case, the physician will postpone the administration of dengvaxia until the patient has recovered; has a weakened immune system, for example due to a genetic defect, hiv infection or therapies that affect the immune system (for example, high-dose corticosteroids or chemotherapy); is pregnant; is breastfeeding.

Use in pregnancy lactation: dengvaxia must not be given to pregnant or breastfeeding women.

If the patient is of child-bearing stage, the patient should take the necessary precautions to avoid pregnancy for 1 month following administration of dengvaxia; is pregnant or breastfeeding, the patient thinks may be pregnant or is planning to have a baby, ask the physician, pharmacist or nurse for advice before receiving dengvaxia.

Special precautions

Inform the physician, pharmacist or nurse before receiving dengvaxia if the patient is taking an immunosuppressive treatment (prednisone or equivalent to 20 mg or 2 mg/kg for 2 weeks or more). The physician will postpone administration of dengvaxia until 4 weeks after the treatment is discontinued; has experienced any health problems after prior administration of any vaccines. The physician will carefully consider the risks and benefits of vaccination.

As with all vaccines, dengvaxia may not protect 100% of persons who have been vaccinated. Vaccination with dengvaxia is not a substitute for protection against mosquito bites. The patient should take appropriate precautions to prevent mosquito bites, including the use of repellents, adequate clothing, and mosquito nets.

Fainting, sometimes accompanied by falling, can occur (mostly in adolescents) following, or even before, any injection with a needle. Therefore inform the physician, pharmacist or nurse if the patient fainted with a prior injection.

Adults above 45 years of age: adults above 45 years of age should not receive the vaccine.

Driving and using machines: no data are available on the effects of dengvaxia on the ability to drive or use machines.

Use in children: children less than 9 years of age should not receive the vaccine.

Side effects

Like all medicines, dengvaxia can cause side effects, although not all patients get them.

Serious allergic reactions: if any of these symptoms occur after leaving the place where the patient received an injection, consult a physician immediately: difficulty in breathing, blueness of the tongue or lips, a rash, swelling of the face or throat, low blood pressure causing dizziness or collapse.

When these signs and symptoms occur they usually develop quickly after the injection is given and while the patient is still in clinic or physician's surgery.

Serious allergic reactions are very rare (may affect up to 1 in 10, 000 people), after receiving any vaccine.

Other side effects: the following side effects were reported during clinical studies in children, adolescents and adults (from 9 to and including 60 years of age). Most of the reported side effects occurred within 3 days after the injection of the vaccine: very common (may affect more than 1 user in 10): headache, muscle pain (myalgia), generally feeling unwell (malaise), feeling of weakness (asthenia), injection site pain, fever.

Common (may affect up to 1 user in 10): injection site reactions: redness (erythema), bruising (hematoma), swelling, and itching (pruritus).

Uncommon (may affect up to 1 user in 100): infections of the upper respiratory tract, dizziness, sore throat (oropharyngeal pain), cough, runny nose (rhinorrhea), nausea, skin eruption (rash), neck pain, hardening of skin at the injection site (injection site induration).

Additional side effects in adults (from 18 to and including 60 years of age): uncommon (may affect up to 1 user in 100): swollen glands (lymphadenopathy), migraine, joint pain (arthralgia), flu-like symptoms (influenza-like illness).

Additional side effects in children and adolescents (from 9 to and including 17 years of age: uncommon (may affect up to 1 user in 100): itchy rash (urticaria).

Reporting of side effects or any suspected adverse event: if the patient experiences any side effects after vaccination, advised to seek immediate medical attention.

By reporting side effects, it can help provide more information on the safety of the vaccine.

Click to view adr monitoring form

Interactions

Using other medicines and dengvaxia: dengvaxia may not have an optimal effect if it used at the same time as medicines that suppress the immune system such as corticosteroids or chemotherapy.

Inform the physician, pharmacist or nurse if the patient is taking or has recently taken any other vaccines or any other medicines, including medicines obtained without a prescription.

Caution for usage

Before administering any biological, the person responsible for administration must take all precautions to prevent allergic or other reactions. As with all injectable vaccines, appropriate medical treatment and supervision must always be readily available in the event of an anaphylactic reaction following the administration of dengvaxia.

Epinephrine (1: 1000) and other appropriate agents used to control immediate allergic reactions must be available to treat unexpected events such as anaphylaxis.

Dengvaxia must not be mixed with other medicinal products in the same syringe.

Dengvaxia must not be administered by intravascular injection under any circumstances.

Syncope (fainting) can occur following, or even before, any vaccination as a psychogenic response to injection with a needle. Procedures should be in place to prevent injury from falling and to manage syncopal reactions.

Separate syringes and needles, separate injection sites and preferably separate limbs must be used if any other vaccine (s) or medicinal product (s) is/are concomitantly administered.

Dengvaxia is reconstituted by transferring all the solvent (0.4% sodium chloride solution) provided in the blue-labeled pre-filled syringe into the vial of freeze dried powder with a yellowish green flip off cap. The pre-filled syringe is fitted with a sterile needle for this transfer. The vial is then gently swirled. After complete dissolution, a 0.5 ml dose of reconstituted suspension is withdrawn into the same syringe. For injection, the syringe should be fitted with the new sterile needle.

The suspension should be visually inspected prior to administration. After reconstitution, dengvaxia is clear, colorless liquid with the possible presence of white to translucent particles (of endogenous nature).

After reconstitution with the solvent provided, dengvaxia must be used immediately.

Any unused dengvaxia or waste material should be disposed of, preferably by heat inactivation or incineration, in accordance with local regulations.

Do not throw away any medicines via wastewater or household waste. Ask a pharmacist on how to throw away medicines that no longer use. These measures will help to protect the environment.

Storage

Store in a refrigerator. Do not freeze. Keep the vaccine in the outer carton in order to protect it from light.

Description

After reconstitution, one dose (0.5 ml) contains 4.5-6.0 log10 ccid50* of each serotype of the cyd dengue virus** (1, 2, 3 and 4).

* ccid50: 50% cell culture infectious dose.

** produced in serum-free vero cells by recombinant dna technology.

The powder is a white, homogenous, freeze-dried powder with possible retraction at the base, and may form a ring-shaped cake.

The solvent (0.4% sodium chloride solution) is a clear, colorless liquid.

After reconstitution with the solvent provided, dengvaxia is a clear, colorless liquid with the possible presence of white to translucent particles.

Excipients/inactive ingredients: essential amino acids including l-phenylalanine, non-essential amino acids, l-arginine hydrochloride, sucrose, d-trehalose dihydrate, d-sorbitol, trometamol, urea, sodium chloride, water for injections.

Mechanism of action

Dengvaxia contains dengue virus serotypes 1, 2, 3 and 4 that have been weakened. Dengvaxia works by stimulating the body's natural defenses (immune system), which produces its own protection (antibodies) against the viruses that cause dengue disease.

Dengue is a viral infection transmitted to humans through the bite of an infected aedes mosquito. Dengue is not transmitted directly from person-to-person. Nevertheless the virus which replicates in an infected individual can be transmitted to other humans through mosquito bites for 4-5 days (maximum 12 days) after the first symptoms appear.

Dengue disease results in a wide range of symptoms including fever, headache, pain behind the eyes, muscle and joint pain, nausea, vomiting, swollen glands or skin rash. Symptoms usually last for 2-7 days. Dengue disease can also be asymptomatic.

However, occasionally dengue can be severe and potentially lead to hospitalization and in rare cases to death. Severe dengue is characterized by high fever and any of the following symptoms: severe abdominal pain, persistent vomiting, rapid breathing, severe bleeding, bleeding in stomach, bleeding gums, fatigue, restlessness, coma, seizure and organ failure.

Source:- http://www.mims.com/philippines/drug/info/dengvaxia

More information about dengvaxia - first vaccine against dengue

Sanofi awaits govt approval to launch dengue vaccine in india

Sanofi pasteur - dengue vaccine frequently asked questions

19 people found this helpful

Piles - Diagnosis and Treatment

MBBS, MS - General Surgery
General Surgeon, Bangalore
Piles - Diagnosis and Treatment

Piles or haemorrhoids are swollen veins in the rectum or anus. They can have a lot of possible causes, but the exact reason is still unknown. The one most common reason that researchers cite is the excessive straining during bowel movement and increased pressure on the veins during pregnancy. Some of the common signs of this condition include discomfort, bleeding, and itching. A clot can be witnessed occasionally. There could be swelling around the anus as well.

How is a pile diagnosed?
Doctors often recognize this condition just by doing a physical exam of the rectum. By lubricating the glove and inserting a finger into the rectum, a doctor can gauge any unusual growth around the rectum area. A doctor might also use a sigmoidoscopy or a proctoscopy to witness the lower portion of the colon. Apart from this, a doctor might prescribe a colonoscopy, if he fathoms that there is a possibility of colorectal cancer or a disease related to the digestive system.

Treatment of piles

  1. Medication: In case of mild discomfort, a doctor might prescribe over-the-counter pads, ointments, creams or suppositories. Products such as these contain lidocaine, witch hazel or hydrocortisone that can relieve a person from itching and pain. One should stop consuming over-the-counter medicine, if there is no change in the condition.
  2. Haemorrhoid thrombectomy: If a clot has appeared along with a pile in the rectum, a doctor can remove it by making an incision and draining the clot. This can fetch instant relief. The best time to do this is within 72 hours of clot formation.
  3. Minimally invasive procedures: 
    • Rubber band litigation: This form of surgery involves placing of a couple of rubber band at the base of the piles to cut off blood circulation. In due course, the haemorrhoids fall off. Although this form of treatment works for many people, the patient has the risk of bleeding within few days of placing the rubber band.
    • Sclerotherapy: This form of treatment involves injecting a chemical into the haemorrhoid. The chemical shrinks the piles within few days. There is hardly any pain involved with sclerotherapy.
  4. Surgical procedure:
    • Haemorrhoidectomy: This is the process by which a surgeon eradicates the excess tissue that might be causing the piles. The patient is sedated before performing this procedure. Some amount of pain is experienced after the procedure is over. The temporary difficulty of urination can be faced by a patient after this procedure.
    • Stapled hemorrhoidopexy: This surgery is only performed for internal haemorrhoids. The process involves blocking the blood supply. The process of stapling has less pain compared to a Haemorrhoidectomy. On the flip side, studies have shown that this procedure has an increased chance of recurrence of haemorrhoids.

In case you have a concern or query you can always consult an expert & get answers to your questions!

2908 people found this helpful

Lip Augmentation - Facts You Must Know About It!

MCh - Plastic and Reconstructive Surgery, MS - General Surgery, MBBS
Cosmetic/Plastic Surgeon, Delhi
Lip Augmentation - Facts You Must Know About It!

Lip augmentation is a restorative (cosmetic) procedure where your lips are reshaped to make them appear fuller. Cosmetic procedures are done for aesthetic improvement, but surgical lip augmentation is performed if the lips are affected by any congenital condition or tissue trauma.

Dermal fillers are mostly used to enlarge the lips. Previously, collagen was the most popular filler, but currently, due to various health reasons, doctors do not use it as often as before. Now, hyaluronic acid fillers are the most popular dermal filler.

Hyaluronic acid is naturally available in your body, especially in your neural, epithelial and connective tissues. The fillers that doctors presently use are chemically similar to hyaluronic acid. It is extremely beneficial in adding volume to your lips.

Applications of Hyaluronic acid

  • Hyaluronic acid fillers improve your lips’ appearance by boosting their shape, structure and volume.
  • The effects of such fillers last approximately for six months; you would require more injections after that.
  • Restylane and Juvederm are the most popular hyaluronic acid fillers used currently. These also contain lidocaine in them, which is a local anaesthetic.

Hyaluronic acid fillers also include the following benefits:

  • The amount of filler to be injected is easily controllable, so the doctor can regulate the amount of volume to create.
  • The injections are given at a steady pace, so the development can be carefully monitored to achieve the desired result.
  • Any bump or lump caused by moving the lips too much is easier to correct.
  • In relation to other dermal fillers, there will be reduced swelling and bruising.
  • Results last for a longer duration, but they are not permanent.
  • Collagen fillers required an allergy test before the procedure could begin, but that is not the case with hyaluronic fillers. Hyaluronic acid fillers are not allergens since they are made from similar substances found in the body.

Risks of lip augmentation
Like every surgical procedure, lip augmentation too has certain risks involved. Some of the contraindications (situational dangers of certain drugs or procedures) include:

In case you have a concern or query you can always consult an expert & get answers to your questions!

2784 people found this helpful

Dermabrasion: Procedures and Results

MCh - Plastic and Reconstructive Surgery, MS - General Surgery, MBBS
Cosmetic/Plastic Surgeon, Chennai
Dermabrasion: Procedures and Results

Dermabrasion is a skin related treatment used by cosmetic surgeons and dermatologists to cure a number of ailments that may leave your skin looking less than healthy. This method basically employs a technique that removes the upper layers of your skin with the help of a rough edged diamond wheel or a wire brush. These edges are called a burr or a fraise.

Here is everything you need to know about the procedure as well as the results that it can yield:

  • Areas and Conditions: The most common areas where this procedure is conducted include the face as well as the neck. It is mostly used to treat people who want to remove fine lines that form around the eyes and the mouth, as well as patients who are suffering from acne scars and other inflammation causing skin ailments as well as abrasions due to injuries.
  • Preparation: The procedure includes cleaning and marking the area that is being treated. This is the first step that helps in seeing exactly what needs to fixed, the extent of the damage and the intensity of the treatment to be employed. Following this process, the doctor will administer a local anaesthesia such as, Lidocaine that will numb the area before the actual treatment begins so that the patient does not undergo any discomfort. Also, with this purpose in mind, the dermatologist may also apply ice packs on the face and neck of the patient so as to make the skin even more numb and remain like that for a longer period of time. Additionally, the skin may be sprayed with a freezing cryogenic spray in order to retain the numbness and keep the skin firm enough for effective treatment. If the doctor is going to treat deeper abrasions or the entire face, then pain killers and general anaesthesia may be used.
  • Procedure: To begin with, a small area is exposed to the treatment at a time, rather than the entire area or face at one time. After the freezing spray is administered, the doctor may run the rotating brush or burr to remove the top layers of the skin. Gauze will be kept handy so as to stem any bleeding that may take place during the process. Finally, the area will be covered with the help of ointment and dressing.
  • Results: The recovery time is said to take anywhere between five to eight days. But this also depends on the severity of condition that was treated, as well as the area that was covered. Little or no pain may follow and regular cleaning will be required. To prevent re-occurrence or re-growth of the problem, follow up visits to the dermatologist will be required.
1 person found this helpful

Premature Ejaculation: What Should You Know About It?

MD - Psychiatry, Diploma in Psychological Medicine, MBBS
Sexologist, Mumbai
Premature Ejaculation: What Should You Know About It?

My last article gave insight on the non-medical methods of controlling premature ejaculation Now, as a wrap up on this topic, I will highlight the options of medical treatments available for managing P.E. However, take it as a warning that you must consult your doctor before trying out any of these methods and medicines, because more often than not, such drugs and medicines have their side effects that can adversely bother your health.

By now we know that Premature ejaculation (PE) occurs when a man reaches peak of sexual excitement and ejaculates before he actually wants it to happen, thus, leaving his partner deprived of the sexual pleasure that she deserves. Even the most empathetic female partner would not like his man to leave her unsatisfied in bed.  Sooner or later this problem becomes a medical problem, reduces the warmth in their relationship.

Several factors including psychological problems such as anxiety; biological problem like penile hypersensitivity, hormonal imbalance (e.g. thyroid problem); behavioural problem like, habituation of quick sex/masturbation, etc may be held responsible for causing PE.

Medical (Allopathic) therapy for PE treatment:

Drugs used for managing premature ejaculation reduce sensitivity and anxiety, improve blood flow and even affect some chemical mediators present in the brain. These class of drugs include local anaesthetics, antidepressants and phosphodiesterase-5 inhibitors.

Anaesthetic compounds were the first medical treatment proposed for PE management. They were applied topically to the surface of skin. Lidocaine-prilocaine sprays or creams decrease the sensation of the penis and increase the time taken to ejaculate during vaginal penetration. These sprays/ creams are applied 10 to 20 minutes prior to sexual activity. Side effects of topical agents include partial loss of sensation of penis, absorption in vagina resulting in vaginal numbness and irritation.

Earlier agents like Alpha Amino Benzoate and Phenoxybenzamine were used to prolong duration of intercourse, but they were associated with severe side effects.

It has been found that Serotonin (a chemical in brain) levels were deficient in PE patients. Treatment medications include Selective Serotonin Reuptake Inhibitors (SSRIs), which interact with a receptor (5-HT2C) present in brain and increases the production of Serotonin. They also help in reducing anxiety and depression associated with PE. Through this mechanism, they prolong the time to reach ejaculation. Several SSRIs have increasingly become used as 'off-label' for PE.

Among the available SSRIs, Paroxetine-Dapoxetine is more beneficial with lesser side effects as compared to other SSRIs. These medications are associated with sexual side effects including decreased fertility and erectile dysfunction. Dapoxetine is a recent SSRI which acts quickly and cleared rapidly from the body. Adverse effects with SSRIs are usually minor and include fatigue, mild nausea, loose stools and sweating. Other side effects may include decreased sexual urge and increased tendency to suicide, especially with long-term use of Paroxetine.

Another potential medical treatment option for PE are class of medications which increase the blood flow by dilating the blood vessels of penile region and prolong the PE. But headache, dizziness, flushing, body-ache associated with them have limited their use in PE.

At present, clinicians need to consider all treatment modalities when evaluating a man with PE, as each patient may respond differently and experience variable side effects. Additional and more effective therapies need to be developed having least side effects.

Ayurvedic therapy for PE treatment:

Vajikaran in Ayurveda is an important treatment modality which increases sexual capacity and improves health. In Sanskrit, Vaji means horse, the symbol of sexual potency and performance thus Vajikaran means producing a horse's vigour, particularly the animal's great capacity for sexual activity in the individual. Vajikaran therapy reenergizes all the seven dhatus (body elements), and restores equilibrium and health. It also offers a solution to minimize the shukra (sperm and ovum) defects.

There are many formulations which are used in Vajikaran. Some of the commonly used formulations include Vrihani GutikaVrishya Gutika, Vajikaranam Ghritam and Upatyakari Shashtikadi Gutika.

Vrihani Gutika is one of the potent formulations while Vrishya Gutika is highly potent aphrodisiac used in treatment of PE. Vajikaranam Ghritam enhances the strength of penis. Upatyakari Shashtikadi Gutika is useful for the enhancement of the fertility.

Also, Chapdraprabha Vati and Kaunch Pak are known to increase sexual vigour and semen consistency helping in increase in sexual timing.

So, with this concluding article, I wrap up my knowledge and experience in treating patients suffering from premature ejaculation. Take care, and stay healthy!

In case you have a concern or query you can always consult an expert & get answers to your questions!

7137 people found this helpful

Table of Content

About Lignox Adr 2% Injection
When is Lignox Adr 2% Injection prescribed?
What are the side effects of Lignox Adr 2% Injection ?
Key highlights of Lignox Adr 2% Injection
What are the substitutes for Lignox Adr 2% Injection ?