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Overview

Levofloxacin 500 MG Tablet

Manufacturer :  Wockhardt Ltd
Medicine Composition :  Levofloxacin
Prescription vs OTC : Prescription by Doctor not required

About Levofloxacin 500 MG Tablet

Levofloxacin 500 MG Tablet is an antibiotic, used to treat bacterial infections. This tablet is a member of the fluoroquinolone antibiotic family. Levofloxacin 500 MG Tablet fights against bacterial infections like tuberculosis, pneumonia, laryngitis, cellulitis, gastroenteritis, acute or chronic bronchitis, urinary tract infections, tonsillitis, anthrax and plague.

Levofloxacin 500 MG Tablet fights against bacteria that are Gram-positive as well Gram-negative. This broad-spectrum antibiotic is effective in inhibiting the synthesis of enzymes called DNA gyrase, which is essential to the process of replication and division of bacterial cells. Thus, Levofloxacin 500 MG Tablet inhibits the cell division of the bacteria, making it impossible for them to survive. This makes it effective in treating bacterial infections.

You should inform your doctor before beginning this medicine, if you suffers from conditions like:

  • Myasthenia gravis
  • Heart disease
  • Liver damage
  • Tendonitis
  • Kidney failure
  • Diabetes

This medication works by killing the bacteria that are causing an infection. It hinders the process of cell replication and cell division, within the cell of the bacteria, by inhibiting the synthesis of the DNA gyrase enzyme. Without this enzyme, the cell of the bacteria cannot survive or grow. Hence, this medication behave as bactericide.

The doctor will prescribe instructions for taking this medication according to your condition and the other medications you are taking. It is important to complete the course that the doctor prescribes, even if the symptoms disappear, or else the infection might recur.

Do not double up the dosage to make up for a forgotten one, as an excess of this medicine can lead to overdosing. Avoid using Levofloxacin 500 MG Tablet during pregnancy, unless the benefit justifies the potential risk to the fetus.

Although this rarely occurs, it is possible, for you to have an allergy to Levofloxacin 500 MG Tablet. An allergic reaction would cause symptoms such as hives, swollen lips, face or tongue, severe skin rashes, sore throat, rapid heart rate and difficulty breathing. It is advisable to stop taking this medicine immediately, if you experience the symptoms of an allergic reaction and consult with your doctor.

    What are the uses of Levofloxacin 500 MG Tablet

    What are the contraindications of Levofloxacin 500 MG Tablet ?

    What are the side effects of Levofloxacin 500 MG Tablet ?

    Key highlights of Levofloxacin 500 MG Tablet

    • How long is the duration of effect?

      The effect of Levofloxacin 500 MG Tablet lasts for an average duration of 16 to 20 hours.

    • What is the onset of action?

      The top effect is usually observed in 1 to 3 hours after administration.

    • Are there any pregnancy warnings?

      It is not advised for pregnant women and should not be used unless extremely necessary.

    • Is it habit forming?

      No habit forming tendency has been reported for this medication.

    • Are there any breast-feeding warnings?

      Breastfeeding women must consult doctor before using this medication.

    • Does this affect kidney function?

      Caution must be taken in patients with kidney disease. Adjustment of dose might be needed. Kindly consult your doctor before taking this medicine.

    • Does this affect liver function?

      Limited information is available on the use of this medicine in patients with liver disease. Kindly consult your doctor before taking this medicine.

    • Is it safe to drive while on this medicine?

      This medicine causes side effects which affects the alertness of the patient, thus driving must be avoided.

    • Is It safe with alcohol?

      Consumption of alcohol is found to be safe with this medication.

    What are the substitutes for Levofloxacin 500 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Levofloxacin 500 MG Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose of this medication, take the missed dose as soon as you remember. If it's almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

    • Are there any overdose instructions?

      Contact the doctor in case of an overdose.

    How does this medication work?

    This medication belongs to the class fluoroquinolones. It works as a bactericidal by inhibiting the bacterial DNA gyrase enzyme which is essential for DNA replication, transcription, repair, and recombination. This leads to expansion and destabilization of the bacterial DNA which causes cell death.

      What are the interactions of Levofloxacin 500 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Evaluation of organ system functions (renal, hepatic, ophthalmologic, and hematopoietic) is recommended periodically during therapy; the possibility of crystalluria should be assessed; WBC and signs of infection .
      • Interaction with Medicine

        • Antineoplastic agents may decrease the absorption of quinolones.
        • Cimetidine, and other H2 antagonists may inhibit renal elimination of quinolones.
        • Foscarnet has been associated with an increased risk of seizures with some quinolones.
        • Loop diuretics: Serum levels of some quinolones are increased by loop diuretic administration. May diminish renal excretion.
        • NSAIDs: The CNS stimulating effect of some quinolones may be enhanced, resulting in neuroexcitation and/or seizures.
        • Probenecid: Blocks renal secretion of quinolones, increasing concentrations.
        • Warfarin: The hypoprothrombinemic effect of warfarin is enhanced by some quinolone antibiotics. Levofloxacin does not alter warfarin kinetics, but may alter the gastrointestinal flora. Monitor INR closely during therapy.
      • Interaction with Food

        Information not available.
      • Interaction with Disease

        • Central Nervous System Depression : You may experience tremors, restlessness, anxiety, confusion, hallucinations upon taking fluoroquinolones. Avoid using caffeine-containing products.
        • Colitis : Avoid taking this medicine if it results in severe diarrhea, abdominal pain, and blood in stools. Consult your doctor you are having any gastrointestinal diseases. Drink adequate amount of water to prevent dehydration.
        • Qt Prolongation : Avoid taking this medicine if you experience any discomfort in your chest. Regular cardiac function tests are to be performed if you have any heart disease (arrhythmia) or family history of heart disease.
        • Kidney Disease : Avoid using Levofloxacin 500 MG Tablet if you experience abdominal pain, diarrhea and joint pain. The medicine accumulates in the body due to impaired kidney function, putting you at high risk. Regular kidney function tests are to me performed if you are on Levofloxacin 500 MG Tablet. Appropriate dose adjustments are to be made under doctor's supervision.

      FAQs about Levofloxacin 500 MG Tablet

      • Ques : What is Levofloxacin 500 MG Tablet?

        Ans : It performs its action by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents the bacterial cells from dividing and repairing, thereby killing them. This medication is used to treat conditions such as Cystitis, Pyelonephritis, Nongonococcal Urethritis, Skin and structure Infection, Pneumonia, etc.

      • Ques : What are the uses of Levofloxacin 500 MG Tablet?

        Ans : It is used for the treatment and prevention from conditions such as Cystitis, Pyelonephritis, Nongonococcal Urethritis, Skin and structure Infection, and Pneumonia.

      • Ques : What are the Side Effects of Levofloxacin 500 MG Tablet?

        Ans : Side effects include Diarrhea, Abdominal pain, Confusion, Fever, Redness of skin, Change in taste, Constipation, Dizziness, Headache, and Nausea or vomiting.

      • Ques : What are the instructions for storage and disposal Levofloxacin 500 MG Tablet?

        Ans : It should be kept in a cool dry place and in its original pack. Make sure this medication remains unreachable to children and pets.

      • Ques : Is Levofloxacin 500 MG Tablet safe?

        Ans : Levofloxacin 500 MG Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose.

      • Ques : What if I forget to take a dose of Levofloxacin 500 MG Tablet?

        Ans : If you forget a dose of Levofloxacin 500 MG Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time.

      • Ques : Can the use of Levofloxacin 500 MG Tablet cause diarrhea?

        Ans : Yes, the use of Levofloxacin 500 MG Tablet can cause diarrhea. It is an antibiotic which kills the harmful bacteria.

      • Ques : Can I stop taking Levofloxacin 500 MG Tablet when I feel better?

        Ans : No, do not stop taking Levofloxacin 500 MG Tablet and complete the full course of treatment even if you feel better.

      • Ques : Can the use of Levofloxacin 500 MG Tablet increase the risk of muscle damage?

        Ans : Yes, the use of Levofloxacin 500 MG Tablet is known to increase the risk of muscle damage, commonly in the ankle. Inform your doctor if you feel any kind of muscle pain while using this medicine.

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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