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Overview

Imuza 50 MG Tablet

Imuza 50 MG Tablet

Manufacturer: Panacea Biotec Ltd
Medicine composition: Azathioprine
Prescription vs.OTC: Prescription by Doctor required

Imuza 50 MG Tablet acts as an immuno-suppressant drug, which is used to treat ulcerative colitis, rheumatoid arthritis, Crohn's disease, and in kidney transplants to prevent the rejection of a new kidney. Imuza 50 MG Tablet is also an anti-metabolite. It works by lowering the body's immune system against the transplanted kidney. Close monitoring of blood cell count is necessary while taking this medication so It should be used under the supervision of a qualified physician. It can be administered by mouth or injected into a vein.

Do not use this medicine if you are allergic to any ingredient in Imuza 50 MG Tablet; if you are pregnant, if you have used alkylating agents in the past, or you are currently taking febuxostat or mercaptopurine. Inform your doctor if you have the following medical conditions to make sure this medicine will be safe for you :

  • kidney or liver disorders
  • bowel problems
  • a history of frequent, recurrent, or prolonged infection
  • scheduled to receive a vaccination or immunisation shortly.
  • a history of cancer, anaemia, bone marrow problems, unusual bruising or bleeding, or low white blood cell or platelet levels.
  • any enzyme deficiencies or recent blood transfusions.

Take this medication with food to reduce stomach upset. Dosage is as directed by your doctor, usually once or twice daily. The dosage is based on your weight, medical condition and response to treatment. If you increase your dose or use this drug more often or for longer than prescribed then you may increase the risk of it's side-effects.

Kidney Transplantation
Imuza 50 MG Tablet is used in kidney transplant patients to prevent transplant rejection.
Imuza 50 MG Tablet is used in the treatment of rheumatoid arthritis which is an inflammatory disease characerized by swelling, pain, and stiffness of joints.
Not recommended in patients with known allergy to Imuza 50 MG Tablet.
Alkylating agents
Not recommended in patients with rheumatoid arthritis previously treated with cyclophosphamide, chlorambucil.
In addition to its intended effect, Imuza 50 MG Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Fever with chills Major Common
Sore throat Major Common
Abdominal pain Major Rare
Loss of appetite Major Rare
Muscle and joint pain Major Rare
Nausea and Vomiting Minor Common
Hair loss or thinning of the hair Minor Rare
Duration of effect
The duration of action of this medicine is not clinically established.
Onset of action
The effect of this medicine can be observed in 1 to 2 hours.
Pregnancy warnings
This medicine is not recommended for pregnant women.
Is it habit forming?
No habit forming tendencies were reported.
Breast-feeding warnings
This medicine is not recommended in breastfeeding women.
Below is the list of medicines, which have the same composition, strength and form as Imuza 50 MG Tablet, and hence can be used as its substitute.
Biocon Ltd
Alkem Laboratories Ltd
Rpg Life Sciences Ltd
Glaxosmithkline Pharmaceuticals Ltd
Zydus Cadila
Missed Dose instructions
If you miss a dose of Imuza 50 MG Tablet, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
Overdose instructions
Seek emergency medical treatment or contact the doctor in case of an overdose.
India
United States
Japan
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Interaction with Disease
Disease
Information not available.
Interaction with Alcohol
Alcohol
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Lab Test
Lab
Information not available.
Interaction with Food
Food
Information not available.
Interaction with Medicine
Warfarin Moderate
This medicine may decrease the effect of warfarin. Inform the doctor if you are receiving either of the medications.Seek immediate medical treatment if you have any symptoms of breathing problem, blurred vision, blood clots and swelling of limbs.
Angiotensin converting enzyme inhibitors Moderate
These medications may lower the WBC count and may increase the risk of infections. Usage of antihypertensive medications like enalapril, ramipril, captopril should be reported to the doctor. Seek immediate medical treatment if you have any symptoms of infection like fever, chills, diarrhea, sore throat.
Live attenuated vaccines and related products Major
You may be at the risk of developing infections if these medicines are taken together. Inform the doctor if you had received either of these medicines. Your doctor may postpone therapy based on the condition.

Popular Questions & Answers

I have crohns disease and recently detected h pylori. I have been taking azathioprine for crohns and its been in control. But now I have to start triple therapy for h pylori eradication. Is there any side effects or interactions when azathioprine and triple therapy drugs used simultaneously?

MD-General Medicine, D.M, Gastroenterology & Hepatology
Gastroenterologist, Ahmedabad
I have crohns disease and recently detected h pylori. I have been taking azathioprine for crohns and its been in cont...
No, you may get a bad taste in the mouth or have loose stools for a few days due to the antibiotics, but the therapy will not affect the Crohn’s disease.
1 person found this helpful

I am on prednisolone 30 mg every other day and Azathioprine 50 mg Morning and 100 mg evening to manage polymyositis. I am suffering from cavity and pain in my first molar right lower jaw since 15 for fifteen days and radiate to my right ear and feeling constant pain inside my ear. I took paracetamol 500 mg and then acetofenac 100 mg for pain at night and 100 mg acetofenac in the morning to get relief. I noticed some blood inside of my ear at night which I cleaned with cotton buds and there is no more blood noticed after that but I felt great after that. Now I want to know if I can take some antibiotics to fight this infection if yes, then what antibiotic should I take, what should be the appropriate dose, what should be the frequency and duration of the treatment along with painkillers.

BDS, MDS
Dentist, Gorakhpur
I am on prednisolone 30 mg every other day and Azathioprine 50 mg Morning and 100 mg evening to manage polymyositis. ...
You may have got ear infection which is aggravated or may be overlapped with your tooth related pain. You have to be sure about your problem so that proper treatment can be sought without any delay. You need to visit an ENT specialist first then to a dentist. Tooth related pain can be corrected based on 3 treatment options, that is restoration/ fillings, RCT or extraction. Improper use of antibiotics can lead to more severe infections which will cost more time energy and money. So act wisely.
1 person found this helpful

What is wrangler granulomatosis disease? What are the symptoms and is it permanently curable?

M.D. Consultant Pathologist, CCEBDM Diabetes, PGDS Sexology USA, CCMTD Thyroid, ACDMC Heart Disease, CCMH Hypertension, ECG
Sexologist, Sri Ganganagar
What is wrangler granulomatosis disease?
What are the symptoms and is it permanently curable?
Granulomatosis with polyangiitis (GPA), formerly known as Wegener granulomatosis, is a rare multisystem autoimmune disease of unknown etiology. Its hallmark features include necrotizing granulomatous inflammation and pauci-immune vasculitis in small- and medium-sized blood vessels. Several other drugs may help decrease the function of the immune system cells causing inflammation. They include cyclophosphamide, azathioprine (Azasan, Imuran) and methotrexate (Rheumatrex, Trexall). Rituximab (Rituxan) is another option for treating granulomatosis with polyangiitis.
1 person found this helpful

I am 28 years old, have been on T medrol steroid for 3 months (Nov-Jan), since then I am on azathioprine, azoran, folvite, pentids 800 due to Multiple sclerosis (an autoimmunity disorder), having a lot of hair fall since a month, got my blood checkup done and it showed up iron deficiency, I would like to know if steroid is showing after affects, or it is the iron content or azathioprine, according to internet all of it can cause hair fall. Please advice how can this be treated? Have been to a dermatologist and I am using some minoxidil spray as well as consuming FOLLIHAIR TABLET once daily, no improvement since 15 days, hair fall has gone upto 300 strands a day.

CIDESCO, DGA, DBT, DBC, MBBS
Trichologist, Mumbai
I am 28 years old, have been on T medrol steroid for 3 months (Nov-Jan), since then I am on azathioprine, azoran, fol...
Hello Sneha . yeah both excessive steroid use n low iron levels causes hair fall problems. u cn start having , cap estemo once a day after food for 3 mths. cap eracod once a day after food for 3 mths. tab ener c dissolvable tab early morning empty stomach for 3 mths. use mild medicated shampoo like triclenz hair shampoo for regular use. Use minotress hair solution 5% on scalp for two times per day for 3 mths. n hair problems take long tym to treated so hv patience. drink 2-3 lit of water daily include protein rich foods in ur diet, include green leafy vegetables and fresh fruits in ur diet ,exercise 45 min daily. thanks
1 person found this helpful

I'm suffering from ulcerative colitis. I was diagnosed in 2011 Nov. After doing colonoscopy my doctor told that it has affected my whole colon and suggested me methylprednisolone from 36 mg and decreasing it 4 mg every 5 days and stop it. And I used Azathioprine and mesacol for 4 years. After I started using these medicines I started feeling normal but used to have inflammation sometimes and with using ornidazole for 3 days I used to become normal. In Nov 2015 after doing colonoscopy again my doctor confirmed that it has cured very well and asked me to stop using Azathioprine and continue using mesacol. Now almost after 1 and half year again y symptoms for Ulcerative colitis came back and I had to consult doctor and again after doing sigmoidoscopy it is confirmed that ulcer has started again in my colon. Again I was suggested to methylprednisolone and Azathioprine. Currently I'm under medication. Now with my experience I figured out that over masturbation has caused ulcerative colitis to me. Actual in when I was 12 or 13 I got to know something that happened in my family and it disturbed me a lot and got me into masturbation and now it is causing so many health issues for me. As mentioned earlier I used to have increased inflammation sometimes under medication too, that used to happen when ever I had done masturbation. So, I have decided I won't do it again and by end of 2015 everything was fine it got cured well. Now recently in Feb 2017 I had masturbated twice and my ulcerative colitis came back. Until then I was fine without any problem. Now my question is only masturbating twice has got me again into worse ulcerative colitis, if I have sex then will it worsen my condition? I'm 24 and my parents are started searching matches for me and I'm very confused about what to do. If having sex increases ulcerative colitis then I don't want to get into it as this may lead to colon cancer and surgery all those things. I don't want to risk my health and life. Also my ovaries functioning has decreased. I think the reason for that is also excessive masturbation. Please suggest me something on this.

Gastroenterologist, Hisar
There is no connection between masturbation and ulcerative colitis. Ulcerative colitis is a life long disease which has relapsing remitting course. Stop worrying about masturbation. It has no connection with ulcerative colitis.
2 people found this helpful

Popular Health Tips

Sarcoidosis - Can You Be Suffering From It?

MBBS, MD -Pulmonary Medicine-Tuberculosis ,Respiratory Disease Medicine , Diploma in Tuberculosis and Chest Diseases (DTCD), European Diploma in Respiratory Medicine
Pulmonologist, Delhi
Sarcoidosis - Can You Be Suffering From It?

Sarcoidosis is an inflammatory condition that has been affecting many people of late. In sarcoidosis, tiny granulomas or inflammatory nodules appear in the various organs of the body. The lungs, eyes, skin, and lymph nodes are commonly affected by the condition. Sarcoidosis can also occur in the brain, heart, liver, spleen. The exact trigger for sarcoidosis is not very clearly understood. However, some studies suggest that sarcoidosis may be an outcome of the body reaction (immunological) towards certain allergens, chemicals, viruses or bacteria (foreign bodies).

It should be noted that

  • Incidences of sarcoidosis are common among people in the age group of 20 – 40 years.
  • People with a family history are more likely to be affected by sarcoidosis.
  • Women are more susceptible to sarcoidosis than their male counterparts. The condition is common among the African-Americans.

Signs and symptoms:
The severity and appearance of symptoms depend on the organs affected by the condition. Symptoms of sarcoidosis may appear suddenly or develop gradually (there may also be a relapse). In few exceptions, the affected person may not exhibit any visible symptoms. The symptoms may vary from person to person.

In general, the symptoms include

  • Fever
  • There is weight loss
  • Extreme tiredness and exhaustion
  • There may be swelling of the lymph nodes

Further, the symptoms may include

  • Rashes, sores, and lesions that may appear on the nose, ears or cheeks, certain areas in the skin undergoes discoloration (Sarcoidosis affecting the skin).
  • Breathlessness and chest pain, dry cough that continues for long and wheezing (In the case of the heart being affected).
  • Palpitations and dyspnea, chest pain, edema, syncope or fainting and arrhythmias or irregular beating of the heart (Sarcoidosis affecting the heart).
  • The eyes may appear red. The vision appears blurred. There is a pain in the eyes and light sensitivity (Sarcoidosis affecting the eyes).

Diagnosis and treatment:

  • Physical examination and blood tests
  • Eye tests can aid in the better diagnosis
  • Kidney and liver function tests
  • Imaging tests like CT scan, PET, X-rays, MRI
  • Biopsy

There are instances where sarcoidosis disappears on its own. However, if the condition persists, it is better to seek medical assistance.

Treatment for sarcoidosis include

  • Immunosuppressant drugs: As the name suggests, the immunosuppressant drugs work by suppressing the immune response. Azathioprine and Methotrexate provide great relief from inflammation.
  • Anti-inflammatory drugs such as Corticosteroids are very effective against sarcoidosis.
  • Plaquenil (Hydroxychloroquine) is often used to treat skin sarcoidosis.
  • For patients with Rheumatoid Arthritis related inflammation, doctors recommend Tumor necrosis factor-alpha (TNF-alpha) inhibitors.
  • In the case of organ failure or damage, surgery may be the only option available.

In severe cases, or if left unattended for long, sarcoidosis can result in

  • Cardiac problems, which may prove to be fatal.
  • It can interfere with the normal functioning of the kidney.
  • The lungs may be severely affected and scarred.
  • There may eye inflammation leading to blindness.
  • In some cases, sarcoidosis may affect the nervous system leading to paralysis (though rare).
     
3 people found this helpful

Uveitis - Do You Know It Can Increase The Risk Of Other Diseases?

MBBS, MS - Ophthalmology
Ophthalmologist, Ghaziabad
Uveitis - Do You Know It Can Increase The Risk Of Other Diseases?

Uveitis is a set of inflammatory diseases that results in the swelling and damaging of the eye tissue. It can lead to temporary or permanent loss of vision. This disease often affects a part of the eye called the uvea, from which it has derived its name. It can affect people of all ages and can last from a short to long period of time. Ophthalmologists categorize uveitis into four major parts posterior uveitis, anterior uveitis, panuveitis uveitis and intermediate uveitis. This disease can be infectious or noninfectious, depending on the nature of the infection.

What causes uveitis and what are the major risk factors?
This disease is caused by the eye's inflammatory response and is caused by a series of potential factors such as the following:

  • Immune system attack from the body
  • Eye bruises
  • Eye infection or tumor within the eye
  • Foreign toxins that penetrate the eye

What are the diseases associated with uveitis?
Uveitis is associated with a range of diseases such as multiple sclerosis, Behcet's syndrome, Vogt-Koyanagi-Harada's (VKH) disease, psoriasis, herpes zoster infection, tuberculosis, rheumatoid arthritis, ulcerative colitis, toxoplasmosis, and cytomegalovirus (CMV) retinitis.

What are the typical symptoms of uveitis?
One or both eyes can be affected by uveitis. Some of the common symptoms include pain in the eye, light sensitivity and blurred and dark spots in vision. Moreover, the symptoms might vary from person to person and greatly depends on the type of inflammation. The symptoms also vary according to the type of uveitis.

What is the detection process?
The process of detection starts with a patient's medical history followed by several medical tests to rule out autoimmune disorders. This is followed by an evaluation of the central nervous system to rule out multiple sclerosis. Some of the other tests conducted by ophthalmologists include measuring the ocular pressure, slit lamp exam, funduscopic exam and visual acuity test.

The primary aim of the treatment is to eradicate inflammation, restore vision, prevent tissue damage and reduce pain. The treatment plan depends on the type of uveitis a patient displays. Doctors often suggest a dose of corticosteroid eye drops to arrest the infection in and around the eye. Other treatment methods include the prescription of immunosuppressive agents.

Furthermore, a doctor may suggest steroidal medication in the form of an eye drop, pill or injection. It can also be surgically infused into the eye. Some other agents used for treatment are azathioprine, methotrexate and mycophenolate. Medications such as these require regular monitoring of the blood to check for any side effects. Doctors also suggest biologics such as infliximab, rituximab, and adalimumab. Most of these drugs have a specific target in the immune system.

In case you have a concern or query you can always consult an expert & get answers to your questions!

5044 people found this helpful

Sweet's Syndrome - Causes And Symptoms

MBBS, MD - Dermatology, F.C.P.S.(Dermatology, Venereology & Leprosy), Diploma in Venerology & Dermatology (DVD), DNB (Dermatology)
Dermatologist, Pune
Sweet's Syndrome - Causes And Symptoms

Sweet's syndrome is when you suffer from fever as well as painful skin lesions. These skin lesions usually appear on your head, arms and neck. The cause of Sweet's syndrome is still not known. However, it is known that certain medications, illnesses and infections are a possible trigger for Sweet's syndrome. Sweet's syndrome is such a condition that the symptoms usually go away in a few days but it may come back later on. To know exactly what causes Sweet's syndrome and what the symptoms of it are, read on.

Causes and Risk Factors:
As mentioned earlier, the exact cause of Sweet's syndrome is not known. However, there are certain factors which put you more at risk of getting it than others. Here they are: 

  1. Gender: It has been proven that women are much more likely to get Sweet's syndrome than men.
  2. Age: The young and the elderly are at a risk of getting Sweet's syndrome. However, if you are in between 30 and 60 years of age you are especially at risk.
  3. Illnesses: If you have an upper respiratory infection or inflammatory bowel disease then you are more likely to get Sweet's syndrome compared to others. Flu-like symptoms also put you more at a risk of getting Sweet's syndrome compared to others.
  4. Pregnancy: It has been seen that pregnancy increases your risk of getting Sweet's syndrome.
  5. Drugs: As mentioned earlier, certain antibiotics, nonsteroidal anti-inflammatory drugs as well as azathioprine are all linked to Sweet's syndrome.

Symptoms-

  1. Small Red Bumps: As mentioned earlier, the main symptom of Sweet's syndrome is that you will develop small red bumps on your neck, arms or head. The size of the bumps tend to increase quickly and then they spread into painful clusters.
  2. Fever: A fever is also very symptomatic of Sweet's syndrome. The small red bumps usually appear abruptly after you get a fever.
  3. Upper Respiratory Infection: The small red bumps also appear abruptly after you have got an upper respiratory Infection.

It should be noted that Sweet's syndrome is often associated with cancer and has commonly been linked to leukemia. If you wish to discuss about any specific problem, you can consult a Dermatologist.

4234 people found this helpful

What Are The Causes and Symptoms of Sweet's Syndrome?

MD - Dermatology, MBBS
Dermatologist, Bangalore
What Are The Causes and Symptoms of Sweet's Syndrome?

Sweet's syndrome is when you suffer from fever as well as painful skin lesions. These skin lesions usually appear on your head, arms and neck. The cause of Sweet's syndrome is still not known. However, it is known that certain medications, illnesses and infections are a possible trigger for Sweet's syndrome. Sweet's syndrome is such a condition that the symptoms usually go away in a few days but it may come back later on. To know exactly what causes Sweet's syndrome and what the symptoms of it are, read on.

Causes and Risk Factors:
As mentioned earlier, the exact cause of Sweet's syndrome is not known. However, there are certain factors which put you more at risk of getting it than others. Here they are: 

  1. Gender: It has been proven that women are much more likely to get Sweet's syndrome than men.
  2. Age: The young and the elderly are at a risk of getting Sweet's syndrome. However, if you are in between 30 and 60 years of age you are especially at risk.
  3. Illnesses: If you have an upper respiratory infection or inflammatory bowel disease then you are more likely to get Sweet's syndrome compared to others. Flu-like symptoms also put you more at a risk of getting Sweet's syndrome compared to others.
  4. Pregnancy: It has been seen that pregnancy increases your risk of getting Sweet's syndrome.
  5. Drugs: As mentioned earlier, certain antibiotics, nonsteroidal anti-inflammatory drugs as well as azathioprine are all linked to Sweet's syndrome.

Symptoms-

  1. Small Red Bumps: As mentioned earlier, the main symptom of Sweet's syndrome is that you will develop small red bumps on your neck, arms or head. The size of the bumps tend to increase quickly and then they spread into painful clusters.
  2. Fever: A fever is also very symptomatic of Sweet's syndrome. The small red bumps usually appear abruptly after you get a fever.
  3. Upper Respiratory Infection: The small red bumps also appear abruptly after you have got an upper respiratory Infection.

It should be noted that Sweet's syndrome is often associated with cancer and has commonly been linked to leukemia. If you wish to discuss about any specific problem, you can consult a Dermatologist.

2869 people found this helpful

Reasons Behind Sweet's Syndrome!

MBBS, MD (Skin & V.D. MAMC) - Dermatology
Dermatologist, Delhi
Reasons Behind Sweet's Syndrome!

Sweet's syndrome is when you suffer from fever as well as painful skin lesions. These skin lesions usually appear on your head, arms and neck. The cause of Sweet's syndrome is still not known. However, it is known that certain medications, illnesses and infections are a possible trigger for Sweet's syndrome. Sweet's syndrome is such a condition that the symptoms usually go away in a few days but it may come back later on. To know exactly what causes Sweet's syndrome and what the symptoms of it are, read on.

Causes and Risk Factors:
As mentioned earlier, the exact cause of Sweet's syndrome is not known. However, there are certain factors which put you more at risk of getting it than others. Here they are: 

  1. Gender: It has been proven that women are much more likely to get Sweet's syndrome than men.
  2. Age: The young and the elderly are at a risk of getting Sweet's syndrome. However, if you are in between 30 and 60 years of age you are especially at risk.
  3. Illnesses: If you have an upper respiratory Infection or inflammatory bowel disease then you are more likely to get Sweet's syndrome compared to others. Flu-like symptoms also put you more at a risk of getting Sweet's syndrome compared to others.
  4. Pregnancy: It has been seen that pregnancy increases your risk of getting Sweet's syndrome.
  5. Drugs: As mentioned earlier, certain antibiotics, nonsteroidal anti-inflammatory drugs as well as azathioprine are all linked to Sweet's syndrome.

Symptoms-

  1. Small Red Bumps: As mentioned earlier, the main symptom of Sweet's syndrome is that you will develop small red bumps on your neck, arms or head. The size of the bumps tend to increase quickly and then they spread into painful clusters.
  2. Fever: A fever is also very symptomatic of Sweet's syndrome. The small red bumps usually appear abruptly after you get a fever.
  3. Upper Respiratory Infection: The small red bumps also appear abruptly after you have got an upper respiratory Infection.

It should be noted that Sweet's syndrome is often associated with cancer and has commonly been linked to leukemia. If you wish to discuss any specific problem, you can consult a dermatologist.

4070 people found this helpful