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Overview

Gemkerb 200 MG Injection

Manufacturer: Indswift Laboratories Ltd
Medicine composition: Gemcitabine
Prescription vs.OTC: Prescription by Doctor required

Gemkerb 200 MG Injection is an anticancer chemotherapy drug. This includes treatment for ovarian cancer, breast cancer, lung cancer, bladder cancer, pancreatic cancer and soft tissue sarcoma. It is also sold under the trade name of Gemzar. Gemkerb 200 MG Injection can also be used in combination with other medications as supervised by your doctor. It is an antimetabolite drug. Gemkerb 200 MG Injection is only injected into your vein by IV injection or IV infusion.

Side effects may vary from one person to another. Some people may not experience all of them at the same time. But mainly the common side effects of using Gemkerb 200 MG Injection include fever, mild nausea, diarrhea, hair loss, tiredness, loss of appetite, flu- like signs, eruptions on the skin and low blood count. Should effects continue inform your health care provider.

Before embarking on your Gemkerb 200 MG Injection treatment, notify your doctor of the following pre-existing conditions, if any:

  • If you are already taking any kind of medications, whether it be prescriptive, non-prescriptive, herbal and vitamins .
  • If you are taking any vaccinations.
  • You are allergic to any kind of foods, to Gemkerb 200 MG Injection itself or are receiving radiation treatment.
  • If you are pregnant or planning to become pregnant or are breastfeeding a baby.

As a preventive measure, please do not try to conceive a child while under Gemkerb 200 MG Injection treatment. For both men and women use all kinds of barriers of contraception during this time. Other measures that you can take to keep the side effects at bay include getting yourself regularly checked by your doctor; keeping yourself warm at all possible times to avoid flu or fever; making sure to avoid bleeding as much as possible; drinking plenty of fluids every day; keeping yourself clean at all times, avoiding exposure to the sun by using an umbrella or sunscreen with a minimum of SPF 15 and maintaining a healthy diet and lifestyle.

Gemkerb 200 MG Injection dosage for each person is determined by taking into consideration their individual weight, height, general health and medical history. Gemkerb 200 MG Injection should given to you by trained hands only. When buying a bottle of Gemkerb 200 MG Injection please ensure that it is not cloudy or contains particles.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Oncologist before using this medicine.

Gemkerb 200 MG Injection is used along with other medications in the treatment of pancreatic cancer.
Gemkerb 200 MG Injection is used along with other medications in the treatment of lung cancer.
Gemkerb 200 MG Injection is used along with other medications in the treatment of breast cancer.
Gemkerb 200 MG Injection is used along with other medications in the treatment of ovarian cancer.
Not recommended in patients with known allergy to Gemkerb 200 MG Injection
In addition to its intended effect, Gemkerb 200 MG Injection may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Low WBC and Platelet count Major Common
Pale skin Major Common
Fever Major Common
Nausea and Vomiting Major Common
Diarrhea Major Common
Weakness of arms, hands, legs or feet Major Less Common
Headache Major Less Common
Hair loss or thinning of the hair Minor Common
Drowsiness Minor Common
Skin rash Minor Less Common
Swelling and redness at the injection site Minor Less Common
How long is the duration of effect?
The effect of this medicine lasts for an average duration of 2 to 5 hours.
What is the onset of action?
The peak effect of this medicine can be observed immediately after intravenous injection.
Are there any pregnancy warnings?
This medicine is not recommended for pregnant women.
Is it habit forming?
No habit forming tendencies were reported.
Are there any breast-feeding warnings?
This medicine is not recommended in breastfeeding women.
Below is the list of medicines, which have the same composition, strength and form as Gemkerb 200 MG Injection , and hence can be used as its substitute.
Alkem Laboratories Ltd
Dr. Reddys Laboratories Ltd
Rpg Life Sciences Ltd
Torrent Pharmaceuticals Ltd
Zydus Cadila
Missed Dose instructions
It is advised not to miss any dose. If you missed any dose, you should contact your doctor immediately.
Overdose instructions
Seek emergency medical treatment or contact the doctor in case of an overdose.
India
United States
Japan
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Disease
Disease
Information not available.
Interaction with Alcohol
Alcohol
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Lab Test
Lab
Information not available.
Interaction with Food
Food
Information not available.
Interaction with Medicine
Clozapine Major
These medicines may further lower the white blood cell count if received together. Any symptoms of fever, diarrhea, sore throat, chills should be informed to the doctor. Close monitoring of blood cell count is necessary. An alternate medicine should be considered based on the clinical condition.
Warfarin Moderate
These medications may increase the risk of bleeding if taken together. Close monitoring of platelets count and liver function is necessary. Any symptoms of unusual bleeding, blood in stools, yellow colored eyes and skin should be informed to the doctor. The dose of warfarin or Gemkerb 200 MG Injection should be adjusted based on the clinical condition.
Major
You may be at the risk of developing infections if these medicines are taken together. Inform the doctor if you had received either of these medicines. Your doctor may postpone therapy based on the condition.
Moderate
The effect of antibiotics like ciprofloxacin, ofloxacin, levofloxacin may reduce if taken with anti-cancer agents. The dose of these antibiotics should be adjusted. An alternate class of antibiotic could be considered based on the clinical condition.
Gemkerb 200 MG Injection belongs to antimetabolite. It gets metabolized into diphosphate and triphosphate nucleosides. Diphosphate nucleoside inhibits ribonucleotide reductase which generates deoxynucleoside triphosphates which are essential for DNA synthesis. Thus, the gemcitabine triphosphates compete with deoxynucleoside triphosphates for incorporation into DNA and interfere with DNA synthesis, results in cell death.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

Please suggest. Is administration of 1.4 mg cytogem harmful, please support answer by medical literature.

MBBS, Diploma in Sports Medicine
Doctor, Hyderabad
Please suggest. Is administration of 1.4 mg cytogem harmful, please support answer by medical literature.
Cytogem is administered as a treatment choice for neoplasm tumour. It mainly acts by blocking further multiplication of carcinomatous cells. There will be side effect like nausea vomiting and loss of hair as advised by your physician.

Table of Content

About Gemkerb 200 MG Injection
When is Gemkerb 200 MG Injection prescribed?
What are the contraindications of Gemkerb 200 MG Injection ?
What are the side effects of Gemkerb 200 MG Injection ?
Key highlights of Gemkerb 200 MG Injection
What are the substitutes for Gemkerb 200 MG Injection ?
What are the dosage instructions?
Where is the Gemkerb 200 MG Injection approved?
What are the interactions for Gemkerb 200 MG Injection ?