Gemcitabine is an anticancer chemotherapy drug. This includes treatment for ovarian cancer, breast cancer, lung cancer, bladder cancer, pancreatic cancer and soft tissue sarcoma. It is also sold under the trade name of Gemzar. Gemcitabine can also be used in combination with other medications as supervised by your doctor. It is an antimetabolite drug. Gemcitabine is only injected into your vein by IV injection or IV infusion.
Side effects may vary from one person to another. Some people may not experience all of them at the same time. But mainly the common side effects of using Gemcitabine include fever, mild nausea, diarrhea, hair loss, tiredness, loss of appetite, flu- like signs, eruptions on the skin and low blood count. Should effects continue inform your health care provider.
Before embarking on your Gemcitabine treatment, notify your doctor of the following pre-existing conditions, if any:
- If you are already taking any kind of medications, whether it be prescriptive, non-prescriptive, herbal and vitamins .
- If you are taking any vaccinations.
- You are allergic to any kind of foods, to Gemcitabine itself or are receiving radiation treatment.
- If you are pregnant or planning to become pregnant or are breastfeeding a baby.
As a preventive measure, please do not try to conceive a child while under Gemcitabine treatment. For both men and women use all kinds of barriers of contraception during this time. Other measures that you can take to keep the side effects at bay include getting yourself regularly checked by your doctor; keeping yourself warm at all possible times to avoid flu or fever; making sure to avoid bleeding as much as possible; drinking plenty of fluids every day; keeping yourself clean at all times, avoiding exposure to the sun by using an umbrella or sunscreen with a minimum of SPF 15 and maintaining a healthy diet and lifestyle.
Gemcitabine dosage for each person is determined by taking into consideration their individual weight, height, general health and medical history. Gemcitabine should given to you by trained hands only. When buying a bottle of Gemcitabine please ensure that it is not cloudy or contains particles.
- treatment of breast cancer.
How long is the duration of effect?The effect of this medicine lasts for an average duration of 2 to 5 hours.
What is the onset of action?The peak effect of this medicine can be observed immediately after intravenous injection.
Are there any pregnancy warnings?This medicine is not recommended for pregnant women.
Is it habit forming?No habit forming tendencies were reported.
Are there any breast-feeding warnings?This medicine is not recommended in breastfeeding women.
Missed Dose instructionsIt is advised not to miss any dose. If you missed any dose, you should contact your doctor immediately.
Overdose instructionsSeek emergency medical treatment or contact the doctor in case of an overdose.
Below is the list of medicines, which contains Gemcitabine as ingredient
This medicine belongs to the antimetabolite class of drugs. After ingestion, it metabolized and form diphosphate and triphosphate nucleosides. Diphosphate nucleoside inhibits ribonucleotide reductase which generates deoxynucleoside triphosphates which are essential for DNA synthesis. Thus, the gemcitabine triphosphate competes with deoxynucleoside triphosphates for incorporation into DNA and interferes with DNA synthesis, results in cell death.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Disease
DiseaseInformation not available.
Interaction with Alcohol
AlcoholInteraction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Lab Test
LabInformation not available.
Interaction with Food
FoodInformation not available.
Interaction with Medicine
ClozapineThese medicines may further lower the white blood cell count if received together. Any symptoms of fever, diarrhea, sore throat, chills should be informed to the doctor. Close monitoring of blood cell count is necessary. An alternate medicine should be considered based on the clinical condition.
WarfarinThese medications may increase the risk of bleeding if taken together. Close monitoring of platelets count and liver function is necessary. Any symptoms of unusual bleeding, blood in stools, yellow colored eyes and skin should be informed to the doctor. The dose of warfarin or Gemcitabine should be adjusted based on the clinical condition.
Live vaccinesYou may be at the risk of developing infections if these medicines are taken together. Inform the doctor if you had received either of these medicines. Your doctor may postpone therapy based on the condition.
Fluoroquinolone antibioticsThe effect of antibiotics like ciprofloxacin, ofloxacin, levofloxacin may reduce if taken with anti-cancer agents. The dose of these antibiotics should be adjusted. An alternate class of antibiotic could be considered based on the clinical condition.
Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.
Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.