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Overview

Gabalept 400 MG Capsule

Manufacturer: Micro Labs Ltd
Medicine composition: Gabapentin
Prescription vs.OTC: Prescription by Doctor required

Gabalept 400 MG Capsule is a prescriptive drug primarily used to prevent seizures. It belongs to a class of drugs called anticonvulsants. Aside from seizures, Gabalept 400 MG Capsule is also used to cure hot flashes, restless legs syndrome (RLS) and postherpetic neuralgia. It treats nerve pain in adults by affecting the chemicals and nerve responsible for these pains and seizures. Gabalept 400 MG Capsule is found in capsule, tablet or solution form and can be used in combination with other drugs. Another brand of this medicine is Neurontin which can be given to both adults and children (at least three years of age). Although the same kind, do not substitute one for the other, only use the brand that has been specified by your doctor.

While under Gabalept 400 MG Capsule medication it is advised that you avoid activities that may include lifting heavy objects or driving as common side effects of this drug are feelings of drowsiness, slowing down of cognitive skills and dizziness. Others include problems with coordination, speech problems, nausea, tremors, double vision or sudden jumpy movements. If these effects persist and become more severe with the passage of time notify your physician immediately. Serious side-effects may include anger, restlessness, insomnia, skin rashes. An allergic reaction to Gabalept 400 MG Capsule called anticonvulsant hypersensitivity syndrome can be fatal.

Before taking this medicine inform your doctor of the following conditions mentioned below:

  • If you have kidney or liver disease.
  • If you are already prone to epileptic or other kinds of seizure attacks.
  • If you have diabetes.
  • If you have depression, mood disorders, or harbor thoughts of suicide.
  • If you are pregnant, are planning to become pregnant or are breastfeeding.

The daily dosage for Gabalept 400 MG Capsule in adults is about 300mg to 600mg about three times a day. Measure your dose with a cup or a spoon or a syringe. The gaps between the three doses should not exceed 12 hours. This drug can be taken with or without food. In case of a missed dose take it as soon as possible. Do not drug overdose. If already time for your next dose skip it. Contact your doctor instantly in the case of drug overdose.

Gabalept 400 MG Capsule is used in the treatment of epilepsy which is a brain disorder characterized by uncontrolled jerking movements and loss of consciousness.
Postherpetic Neuralgia
Gabalept 400 MG Capsule is used in the treatment complication of shingles, which is caused by the chickenpox virus characterized by pain or burning sensation of the skin.
Not recommended in patients with known allergy to Gabalept 400 MG Capsule.
In addition to its intended effect, Gabalept 400 MG Capsule may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Dizziness Major Common
Uncontrolled eye movements Major Common
Agitation and anxiety Major Common
Especially in children
Restlessness Major Common
Especially in children
Hyperactivity Major Common
Especially in children
Unusual tiredness and weakness Major Less Common
Irritability Major Less Common
Blurred vision Minor Common
Lower back pain Minor Common
Tremors Minor Common
Increased appetite Minor Less Common
Change in vision Minor Less Common
Dry mouth Minor Less Common
Weight gain Minor Less Common
How long is the duration of effect?
The effect of this medicine lasts for an average duration of 15 to 21 hours.
What is the onset of action?
The effect of this medicine can be observed in 2 to 3 hours.
Are there any pregnancy warnings?
This medicine is not recommended for pregnant women unless necessary. The benefits and risks should be discussed with the doctor before taking this medicine.
Is it habit forming?
No habit forming tendency has been reported.
Are there any breast-feeding warnings?
This medicine is known to excreted through the breast milk. It is not recommended in breastfeeding women unless necessary. Monitoring of drowsiness and body weight is necessary.
Below is the list of medicines, which have the same composition, strength and form as Gabalept 400 MG Capsule, and hence can be used as its substitute.
Sun Pharma Laboratories Ltd
Intas Pharmaceuticals Ltd
Torrent Pharmaceuticals Ltd
Missed Dose instructions
If you miss a dose of Gabalept 400 MG Capsule, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
Overdose instructions
Seek emergency medical treatment or contact the doctor in case of an overdose.
India
United States
Japan
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Interaction with Disease
Impaired kidney function Major
This medicine should be used with caution in patients with kidney impairment. Monitoring of kidney function is necessary. Dose adjustments are to be made based on CrCl.
Interaction with Alcohol
Alcohol Moderate
Consumption of alcohol with this medicine is not recommended as it increases the risk of side effects like dizziness, difficulty in concentration. Do not perform activities that require mental alertness like driving or operating machinery.
Interaction with Lab Test
Lab
Information not available.
Interaction with Food
Food
Information not available.
Interaction with Medicine
Duloxetine Moderate
These medications may cause dizziness, confusion and breathing difficulty if taken together. Inform the doctor if you are receiving antidepressant or antipsychotics. Dose adjustments are to be made if any symptoms appear based on the clinical condition.
Buprenorphine Major
These medications are not recommended together due to the risk of breathlessness and other central nervous system effects. Inform the doctor if you are receiving any antidepressants or antipsychotics. Dose adjustments are to be made if any symptoms appear based on the clinical condition.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

Does gabapentin and dettol la increase blood glucose level? And how much time they take to get out of body?

MBBS, CCEBDM, Diploma in Diabetology, Diploma in Clinical Nutrition & Dietetics, Cetificate Course In Thyroid Disorders Management (CCMTD)
Endocrinologist, Hubli-Dharwad
Does gabapentin and dettol la increase blood glucose level? And how much time they take to get out of body?
Mr. lybrate-user, Thanks for the query. Olmesartan is one of the newer molecules for treatment of high blood pressure. It ha no action of blood glucose. Increase in after food glucose level is directly depending on the quantity food that one takes. More if eat, post food level is bound to go up quite a few mg. Olmesartan is a very good drug for controlling high BP. Thanks.
1 person found this helpful

Can anyone tell me what are these medicines used for? 300 mg gabapentin, 50 mg amitriptyline, 20 mg clonidine. And how a person can get them in India.

PDDM, MHA, MBBS
General Physician, Nashik
Uses for seizures and other neurological diseases. These are prescription medications and can be prescribed by registered doctors only.

I m 24years old and have a severe thigh pain since last 2years. I had taken many medicines like gabapentin, oxetol etc but no relief at all. I am not able to sleep frm that side as it hurts when touched it. I want suggestion what will I do now?

Bachelor of Ayurvedic Medicines and Surgery(BAMS), Post Graduation Diploma in Emergency Medicines And Services(PGDEMS), MD - Alternate Medicine
Ayurveda, Ghaziabad
I m 24years old and have a severe thigh pain since last 2years. I had taken many medicines like gabapentin, oxetol et...
Hi Apply pranacharya restopain oil or prasarini oil on your affected part then give hot fomentation. Take maha rasnadi kwath 2-2 tsf twice a day. And agni tundi vati and maha yograj guggul 1-1 tab twice a day..

I have groin pain since 2 month. MRI done. Annular bulge is there in L4 L5. Taking gabapentin300 mg. Hav visited to physiotherapy also for 10 days. Still not recovered. What to do now. Its very tough.

MD - Alternate Medicine, BHMS
Homeopath, Surat
I have groin pain since 2 month. MRI done. Annular bulge is there in L4 L5. Taking gabapentin300 mg. Hav visited to p...
Try Naturamore Male powder, one spoon daily in warm milk or water for 3-4 months. Also, Chlorophyll powder, one spoon mixed in 200 ml of water daily. It will help you. If you can't find it nearby you, you contact me personally. Take Care :)

I am a 40 year old married lady, with a 10 years son and suffering from abdominal migraine. I am taking gabapentin . What should I do?

CCEBDM, PG Diploma In Clinical Cardiology, MBBS
General Physician, Ghaziabad
Get BP and, thyroid hormones T3 T4 Tsh 1.Sleep . Go to bed and get up about the same times every day, 3. Eat regular meals. 4. Drink plenty of water to avoid dehydration 5. Relax – listen soothing music . Walk for 5 mts 6.avoid .stress, 7. .avoid strong stimuli like loud noises, and smell of food 8. Keep your routine fixed and regular if gabapentin is effective keep taking it. If felt need contact on private chat for medicine good luck.

Popular Health Tips

Seizures - How To Get Rid of It?

MS - General Surgery, MCh - Neuro Surgery, MBBS
Neurosurgeon, Greater Noida
Seizures - How To Get Rid of It?

The primary aim of the treatment in patients suffering from seizure is leasing a seizure-free life without giving way to any adverse effects. This goal can be accomplished in over 60 percent people with the help of anticonvulsants. Some patients also experience adverse effects since they suffer from a seizure which is refractory to medical therapy. Here are some of the common treatment options for seizures:

  1. Monotherapy: Sometimes, monotherapy is given as it reduces the chance of all sorts of adverse effects and even avoids drug interactions. Moreover, this type of treatment approach is much less expensive than polytherapy since many older generation of the anticonvulsant agent comprises of hepatic enzyme which is responsible for reducing the serum level of the concomitant drug which leads to an increase in the dosage level of such medicines.
  2. Social And vocational rehabilitation: People suffering from problems in psychosocial adjustments after the diagnosis may also need social and vocational rehabilitation. Many physicians do not pay enough attention to the consequences that an epilepsy diagnosis may leave on the patient. For instance, people with epilepsy may have a fear of experiencing next attack of seizure and they may be unable to work at heights or drive.
  3. Consulting an expert: It is important to refer patients with intractable spells to epileptologist or neurologist for subsequent workup. A neurosurgical consultation may also be needed when the patient has to be treated surgically.

Importance of anticonvulsant therapy
Patients who have had already suffered from recurrent attacks of unprovoked seizure may need treatment with an anticonvulsant. This treatment is not recommended until the person has risk factors for suffering from the problem yet again. The primary means of treating seizure is anticonvulsant therapy where the most suitable drug is chosen based on accurate diagnosis of the syndrome as a response to specific anticonvulsants may vary from one patient to another. The difference in response may reflect the various pathophysiologic mechanisms in different types of seizures.

Types of anticonvulsant therapy
Some of the anticonvulsant therapy medication may have multiple action mechanism while some have an only single mechanism of action. Some of the most common variants of the therapy include:

  1. Neuronal potassium channel referred to as KCNQ opener
  2. Blockers of unique binding sites such as perampanel, gabapentin, and levetiracetam
  3. H-current modulators such as lamotrigine and gabapentin
  4. Carbonic anhydrase inhibitors such as zonisamide and topiramate
  5. Alpha-amino 3-hydroxy 5-methyl 4-isoxazole propionic acid receptor blockers like topiramate and perampanel.
  6. N and L-calcium channel blockers like zonisamide, valproate, topiramate, and lamotrigine

Even though there are so many types of drugs available, all of them cannot be used for the treatment of seizures. Doctors would evaluate the condition thoroughly before prescribing a medication that can be helpful in reducing the severity of the condition. In case you have a concern or query you can always consult an expert & get answers to your questions!

2540 people found this helpful

Seizures - 3 Ways It Can Be Treated!

MCh - Neurosurgery, MS-General Surgery, MBBS
Neurosurgeon, Delhi
Seizures - 3 Ways It Can Be Treated!

The primary aim of the treatment in patients suffering from seizure is leasing a seizure-free life without giving way to any adverse effects. This goal can be accomplished in over 60 percent people with the help of anticonvulsants. Some patients also experience adverse effects since they suffer from a seizure which is refractory to medical therapy. Here are some of the common treatment options for seizures:

  1. Monotherapy: Sometimes, monotherapy is given as it reduces the chance of all sorts of adverse effects and even avoids drug interactions. Moreover, this type of treatment approach is much less expensive than polytherapy since many older generation of the anticonvulsant agent comprises of hepatic enzyme which is responsible for reducing the serum level of the concomitant drug which leads to an increase in the dosage level of such medicines.
  2. Social And vocational rehabilitation: People suffering from problems in psychosocial adjustments after the diagnosis may also need social and vocational rehabilitation. Many physicians do not pay enough attention to the consequences that an epilepsy diagnosis may leave on the patient. For instance, people with epilepsy may have a fear of experiencing next attack of seizure and they may be unable to work at heights or drive.
  3. Consulting an expert: It is important to refer patients with intractable spells to epileptologist or neurologist for subsequent workup. A neurosurgical consultation may also be needed when the patient has to be treated surgically.

Importance of anticonvulsant therapy

Patients who have had already suffered from recurrent attacks of unprovoked seizure may need treatment with an anticonvulsant. This treatment is not recommended until the person has risk factors for suffering from the problem yet again. The primary means of treating seizure is anticonvulsant therapy where the most suitable drug is chosen based on accurate diagnosis of the syndrome as a response to specific anticonvulsants may vary from one patient to another. The difference in response may reflect the various pathophysiologic mechanisms in different types of seizures.

Types of anticonvulsant therapy
Some of the anticonvulsant therapy medication may have multiple action mechanism while some have an only single mechanism of action. Some of the most common variants of the therapy include:

  1. Neuronal potassium channel referred to as KCNQ opener
  2. Blockers of unique binding sites such as perampanel, gabapentin, and levetiracetam
  3. H-current modulators such as lamotrigine and gabapentin
  4. Carbonic anhydrase inhibitors such as zonisamide and topiramate
  5. Alpha-amino 3-hydroxy 5-methyl 4-isoxazole propionic acid receptor blockers like topiramate and perampanel.
  6. N and L-calcium channel blockers like zonisamide, valproate, topiramate, and lamotrigine

Even though there are so many types of drugs available, all of them cannot be used for the treatment of seizures. Doctors would evaluate the condition thoroughly before prescribing a medication that can be helpful in reducing the severity of the condition.

In case you have a concern or query you can always consult an expert & get answers to your questions!

2734 people found this helpful

Total Knee Replacement - Multimodal Pain Relief After Surgery!

MBBS, DNB (Orthopedics)
Orthopedist, Pune
Total Knee Replacement - Multimodal Pain Relief After Surgery!

Knee replacement can be extremely painful. Previously, opioids or narcotics were administered for pain relief. But excessive addition of opioids is not exactly effective for controlling pain.

Multimodal pain management has become an important part of the perioperative care of patients undergoing total joint replacement. The principle of multimodal therapy is to use interventions that target several different steps of the pain pathway, allowing more effective pain control with fewer side effects. Many different protocols have shown clinical benefit. The goal of this review is to provide a concise overview of the principles and results of multimodal pain management regimens as a practical guide for the management of joint arthroplasty patients.

Multimodal denotes administering two or more than two types of medications that work with different mechanisms. The following are the techniques used:

  1. Pre-operative Femoral Nerve Block: Prior to the surgery, a catheter is placed beside the femoral nerve for blocking it. This nerve is located in the upper thigh. Medication is delivered through the catheter for the nerve to be numbed for 24 hours. Thus, pain signals to the brain are blocked. This method reduces the use of narcotics and the consequent side effects.

  2. Patient Controlled Analgesia (PCA): This method is also known as ‘Pain Pump’. An intravenous pump is used to administer pain relief medications, such as oxymorphone or morphine, after the surgery. The control button of the machine could be pressed, by the patient for 6 to 10 times per hour. The machine is used for two post-operative days.

  3. Oral Medications: The oral medications include Non-Steroidal Anti-Inflammatory drugs or NSAID; such as Celebrex which is similar to aspirin, structurally. Alternatively, acetaminophen, such as Tylenol or its equivalent composition, can also be used.

  4. Acetaminophen: It acts on the Central Prostaglandin Synthesis and relieves the patient of pain through multiple mechanisms.

  5. Epidural Analgesia: It produces lower pain scores and involves less time for achieving physical therapy goals. However, this is subject to side effects such as dizziness, urinary retention and itchiness.

  6. Gabapentinoids: These medications include membrane stabilizers such as Gabapentin and Pregabalin.

The objective of multimodal treatments is to provide quick relief to the patient and immediately so. Earlier the rehabilitation, more successful will be the knee replacement surgery.

In case you have a concern or query you can always consult an expert & get answers to your questions!

2577 people found this helpful

How To Control Pain After Knee Replacement?

MBBS, MS - Orthopaedics, Fellowship Joint Replacement Surgery
Orthopedist, Faridabad
How To Control Pain After Knee Replacement?

Knee replacement can be extremely painful. Previously, opioids or narcotics were administered for pain relief. But excessive addition of opioids is not exactly effective for controlling pain.

Multimodal pain management has become an important part of the perioperative care of patients undergoing total joint replacement. The principle of multimodal therapy is to use interventions that target several different steps of the pain pathway, allowing more effective pain control with fewer side effects. Many different protocols have shown clinical benefit. The goal of this review is to provide a concise overview of the principles and results of multimodal pain management regimens as a practical guide for the management of joint arthroplasty patients.

Multimodal denotes administering two or more than two types of medications that work with different mechanisms. The following are the techniques used:

  1. Pre-operative Femoral Nerve Block: Prior to the surgery, a catheter is placed beside the femoral nerve for blocking it. This nerve is located in the upper thigh. Medication is delivered through the catheter for the nerve to be numbed for 24 hours. Thus, pain signals to the brain are blocked. This method reduces the use of narcotics and the consequent side effects.

  2. Patient Controlled Analgesia (PCA): This method is also known as ‘Pain Pump’. An intravenous pump is used to administer pain relief medications, such as oxymorphone or morphine, after the surgery. The control button of the machine could be pressed, by the patient for 6 to 10 times per hour. The machine is used for two post-operative days.

  3. Oral Medications: The oral medications include Non-Steroidal Anti-Inflammatory drugs or NSAID; such as Celebrex which is similar to aspirin, structurally. Alternatively, acetaminophen, such as Tylenol or its equivalent composition, can also be used.

  4. Acetaminophen: It acts on the Central Prostaglandin Synthesis and relieves the patient of pain through multiple mechanisms.

  5. Epidural Analgesia: It produces lower pain scores and involves less time for achieving physical therapy goals. However, this is subject to side effects such as dizziness, urinary retention and itchiness.

  6. Gabapentinoids: These medications include membrane stabilizers such as Gabapentin and Pregabalin.

The objective of multimodal treatments is to provide quick relief to the patient and immediately so. Earlier the rehabilitation, more successful will be the knee replacement surgery. In case you have a concern or query you can always consult an expert & get answers to your questions!

3756 people found this helpful

Herniated Disc - Effects And Diagnosis!

MS - Orthopaedics, M.Ch Trauma & Ortho, Diploma In Orthopaedics (D. Ortho), MBBS
Orthopedist, Chennai
Herniated Disc - Effects And Diagnosis!

A herniated disc also known as a slip disc or prolapsed disc refers to the problem where one of the discs located in between the bones of the vertebrae(backbone) gets damaged and stacks itself upon the nerves. The tender inner portion of the disc gets protruded over the outer ring. Herniated disc causes severe neck pain and back pain. It occurs when the outer ring gets weak and tears down. The most common symptoms include pain and numbness, especially on one side of the body. The pain extends down to the arms and legs. It worsens during nighttime. The muscles become weak. Overweight people are likely to have this disease, as the discs carry extra weight. Old people are vulnerable to a slip disc.

Effects of Herinated Disc:
- An untreated case of herniated disc may cause permanent damage to the nerves.
- In certain cases, a herniated disc is capable of cutting off nerve impulses to the "caudal equine"nerves, present in the lower back and legs. This leads to loss of bladder control or bowel control.
- Saddle anaesthesia is another long-term effect. Nerves are compressed by the slip disc, causing loss of sensation in the inner portions of your thighs, the back of your legs and surrounding the rectum region.

- Symptoms may improve or worsen.

Diagnosis of Herinated Disc:

Treatment or diagnosis of herniated disc or slip disc can be either conservative or surgical in nature. The nature of treatment is determined according to your discomfort level and the kind of pain you are experiencing, or how much the disc has slipped out.
- The pain caused by herniated disc can be relieved by undertaking an exercise schedule which includes stretching and strengthening the spine and its surrounding muscles.
- A physiotherapist should be appointed for recommending the types of exercises.
- Taking pain relievers also soothes the pain.
- Stronger medicines prescribed by doctors include-muscle relaxers, narcotics to deal with the pain, medicines for nerve pain such as "gabapentin"  or "duloxetine".
- In case of the symptoms not subsiding within a span of six weeks, a surgery may be recommended by your doctor. The surgeon may have to remove the damaged part of the disc. This surgery is called a microdiskectomy.

In case you have a concern or query you can always consult an expert & get answers to your questions!

4896 people found this helpful

Table of Content

About Gabalept 400 MG Capsule
When is Gabalept 400 MG Capsule prescribed?
What are the contraindications of Gabalept 400 MG Capsule?
What are the side effects of Gabalept 400 MG Capsule?
Key highlights of Gabalept 400 MG Capsule
What are the substitutes for Gabalept 400 MG Capsule?
What are the dosage instructions?
Where is the Gabalept 400 MG Capsule approved?
What are the interactions for Gabalept 400 MG Capsule?