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Overview

Fluphenazine

Prescription vs.OTC: Prescription by Doctor required

Fluphenazine is an anti-psychotic medication. It is prescribed to patients with chronic psychoses such as schizophrenia. It is also given to patients for treatment of psychotic symptoms such as hallucinations and delusions. It comes as a tablet and in liquid form for oral consumption. In liquid form it comes with a marked dropper. Consult your doctor regarding the right dosage. It can also be injected in the body for higher dosage.

Common side effects of Fluphenazine are increased weight, movement problems, sleepiness, depression. Other side effects that have been noticed are involuntary choreoathetoid movements, lethargy, nasal congestion, cataract, corneal deposits, corneal opacity, pigment deposits on lens, retinitis pigmentosa, akathisia, dysphagia, dysphasia, chills, sore throat, dark urine, clay-colored stools, jaundice, muscle spasm, tremors, dystonic reaction.

Avoid using this medication in case you are allergic to any of the ingredients or if you have liver disease, brain damage or blood cell disorder. Let your health provider know if you have:

In addition to its intended effect, Fluphenazine may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Dystonia
Weight gain
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Akathisia
Abnormality of voluntary movements
Parkinsonism.
Is It safe with alcohol?
Monazine 25mg injection may cause excessive drowsiness and calmness with alcohol.
Are there any pregnancy warnings?
Monazine 25mg injection may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Are there any breast-feeding warnings?
Unknown. Human and animal studies are not available. Please consult your doctor.
Is it safe to drive while on this medicine?
Caution is advised when driving or operating machinery.
Does this affect kidney function?
Caution to be advised in patients with impaired renal function. Contraindicated in renal failure.
Does this affect liver function?
There is no data available. Please consult doctor before consuming the drug.
Below is the list of medicines, which contains Fluphenazine as ingredient
Mova Pharmaceutical Pvt Ltd
Reliance Formulation Pvt Ltd
Tripada Healthcare Pvt Ltd
Maneesh Pharmaceuticals Ltd
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Interaction with Medicine
Onabet Powder
FLUGEE 150MG TABLET
TRAMAZAC HP 50MG INJECTION
Benadryl Dr Dry Cough Active Relief Syrup
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

I am 27 year old suffering from schizophrenia. I can't study or can't do anything. Taking tablets fludac and trazin h. I feel I am changed. How long it will take to get cured.

MD-PhD, FIPS, Fellow of Academy of General Education (FAGE), DPM, MBBS
Psychiatrist, Ludhiana
Antipsychotic medications reduce the risk of future psychotic episodes in patients who have recovered from an acute episode. Even with continued drug treatment, some people who have recovered will suffer relapses. Far higher relapse rates are seen when medication is discontinued. In most cases, it would not be accurate to say that continued drug treatment ?prevents? relapses; rather, it reduces their intensity and frequency. The treatment of severe psychotic symptoms generally requires higher dosages than those used for maintenance treatment. If symptoms reappear on a lower dosage, a temporary increase in dosage may prevent a full-blown relapse. Because relapse of illness is more likely when antipsychotic medications are discontinued or taken irregularly, it is very important that people with schizophrenia work with their doctors and family members to adhere to their treatment plan. Adherence to treatment refers to the degree to which patients follow the treatment plans recommended by their doctors. Good adherence involves taking prescribed medication at the correct dose and proper times each day, attending clinic appointments, and/or carefully following other treatment procedures. Treatment adherence is often difficult for people with schizophrenia, but it can be made easier with the help of several strategies and can lead to improved quality of life. There are a variety of reasons why people with schizophrenia may not adhere to treatment. Patients may not believe they are ill and may deny the need for medication, or they may have such disorganized thinking that they cannot remember to take their daily doses. Family members or friends may not understand schizophrenia and may inappropriately advise the person with schizophrenia to stop treatment when he or she is feeling better. Physicians, who play an important role in helping their patients adhere to treatment, may neglect to ask patients how often they are taking their medications, or may be unwilling to accommodate a patient?s request to change dosages or try a new treatment. Some patients report that side effects of the medications seem worse than the illness itself. Further, substance abuse can interfere with the effectiveness of treatment, leading patients to discontinue medications. When a complicated treatment plan is added to any of these factors, good adherence may become even more challenging. Fortunately, there are many strategies that patients, doctors, and families can use to improve adherence and prevent worsening of the illness. Some antipsychotic medications, including haloperidol (Haldol®), fluphenazine (Prolixin®), perphenazine (Trilafon®) and others, are available in long-acting injectable forms that eliminate the need to take pills every day. A major goal of current research on treatments for schizophrenia is to develop a wider variety of long-acting antipsychotics, especially the newer agents with milder side effects, which can be delivered through injection. Medication calendars or pill boxes labeled with the days of the week can help patients and caregivers know when medications have or have not been taken. Using electronic timers that beep when medications should be taken, or pairing medication taking with routine daily events like meals, can help patients remember and adhere to their dosing schedule. Engaging family members in observing oral medication taking by patients can help ensure adherence. In addition, through a variety of other methods of adherence monitoring, doctors can identify when pill taking is a problem for their patients and can work with them to make adherence easier. It is important to help motivate patients to continue taking their medications properly. In addition to any of these adherence strategies, patient and family education about schizophrenia, its symptoms, and the medications being prescribed to treat the disease is an important part of the treatment process and helps support the rationale for good adherence.
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Popular Health Tips

Schizophrenia - Know The Different Types & Ways Of Treatment!

Schizophrenia - Know The Different Types & Ways Of Treatment!

Schizophrenia affects over 1% of the world’s population and affects the way a person thinks, feels and behaves. In most cases, it is diagnosed when a person is between the ages of 16 to 25. This condition can be hereditary and is said to affect men more often than women. Schizophrenia is characterized by an inability to distinguish between real and imaginary which can lead to delusions, social withdrawal, hallucinations and other forms of social and occupational dysfunction.

Schizophrenia affects different people in different ways. On the basis of the type of symptoms exhibited, this disease has been categorized into 5 sub types. These are:

  1. PARANOID SCHIZOPHRENIA: This type of schizophrenia is characterized by delusions and hallucinations that may make the person exhibit paranoid behaviour. These people often feel like they are being watched or followed and may have delusions of grandeur. They may also get angry quickly on minor issues and show signs of anxiety and hostility.
  2. DISORGANIZED SCHIZOPHRENIA: In such cases, the person may behave in ways that are difficult to understand or speak in broken sentences and have difficulty structuring a sentence. They may also display inappropriate behaviour and react in ways not suitable to the occasion. People suffering from disorganized schizophrenia may also neglect their personal hygiene.
  3. CATATONIC SCHIZOPHRENIA: People suffering from catatonic schizophrenia may swing between immobility and periods of rapid movement. They may stay quiet for hours or talk rapidly repeating everything they hear. These people have a high risk of harming themselves as they are usually unable to look after themselves and complete daily activities.
  4. UNDIFFERENTIATED SCHIZOPHRENIA: People suffering from this type of schizophrenia exhibit behaviour that fits into more than one type of schizophrenia. From time to time they may have hallucinations, suffer from delusions or display catatonic behaviour and disorganized behaviour or speech.
  5. RESIDUAL SCHIZOPHRENIA: Even though a person may not be currently showcasing any signs of schizophrenia, they are said to have residual schizophrenia. Such people need to have had at least one schizophrenic episode. These people may exhibit symptoms later or be in complete remission.

With schizophrenia, an early diagnosis can make treatment easier and hence if you notice anyone exhibiting signs of schizophrenia, you must advise them to seek medical help immediately.

Typical and Atypical Antipsychotic Agents

Commonly prescribed typical antipsychotics include:

Commonly prescribed atypical antipsychotics include:

Most psychotropic medications produce the best results when paired with some type of psychotherapy. Medication can be of great service in helping a person treat and overcome debilitating symptoms, but pills by themselves cannot address behaviors, emotions, and root causes of mental health issues. If you are prescribed an antipsychotic medication, please consider finding a therapist you trust to help you learn more about what you are experiencing and to help you develop coping strategies to improve the quality of your life.

Schizophrenia cannot be cured but it can be managed with a combination of typical or atypical medication and cognitive therapy. The latter can be in the form of self-help groups, housing and employment programs, counselling and therapy.

In case you have a concern or query you can always consult an expert & get answers to your questions!

4164 people found this helpful

Schizophrenia - Symptoms, Causes, Treatment And Prevention!

MBBS
Internal Medicine Specialist, Delhi

Schizophrenia:

Schizophrenia is a severe mental illness that leads people to interpret reality in an abnormal way. People with Schizophrenia experience hallucinations, get false illusions, and display an unusually disordered behaviour, which negatively impacts their daily life .

Schizophrenia is a serious condition that requires treatment for a lifetime. Early diagnosis and treatment can keep symptoms under control and prevent any serious complications from building up.

Symptoms:

Schizophrenia is mainly associated with cognitive problems that is exhibited in a person's daily behavior or state of emotions. Though there may be difference in signs and symptoms across patients, but it majorly involves hallucinations, delusions, disordered speech, and impaired body  functionalities. Common symptoms are:


- Delusions. These are false conceptions and interpretations of reality. For instance, a person with schizophrenia can have various delusions. He might think that he is targeted or harassed; he has supernatural abilities or power; he remembers his past life; or a huge tragedy is going to happen.
- Hallucinations. People with schizophrenia  may see or hear things that do not exist. Such hallucinations have a powerful force and feel like a normal experience. Hallucinations can impact all the senses, but most commonly it is associated with hearing strange voices.
- Disordered thought (speech).Schizophrenia affects the cognitive abilities of a person. Often, it results in impaired speech ability and meaningless communication.  People experiencing this ask questions that are partially or totally unrelated. Their speech is broken and without any clear sense or meaning.
- Highly disoriented motor behavior. Schizophrenia might lead people to behave weirdly. Sometimes, they may show childlike absurdity to episodic aggressiveness. The behavior is erratic and without any intention. You may notice people suffering with schizophrenia showing resistance to instructions, improper or eccentric posture, irresponsible reactions , or silly and unnecessary movement.
- Negative/withdrawal symptoms. This happens when there a person shows lessened or resistance to function normally. For instance, the person may disregard personal hygiene or be immune to any kind of emotion; does not respond to eye contact, shows no facial expressions or talks in a monotone). The person may withdraw himself from the society and refuse to part take in daily activities. Such persons are incapable of finding happiness in any thing and remain negative towards life.
Symptoms differ in form and severity and may change over time, sometimes with worsening show of symptoms and sometimes showing reduced impact. However, they do not go completely.
Men with schizophrenia may show signs of the disorder in the early to mid-20s. Women start displaying the impact of the mental condition during their late 20s. The mental illness is rare in children and those who are aged 45 and above.

Symptoms in teenagers

Teenagers with Schizophrenia may have symptoms same as that of adults, though  it might be difficult to identify the condition in teenagers as in adults . This is because a few of the early signs of schizophrenia in teenagers are usually the same as seen during the typical growth in teen years and noticeable change in behavior, like:

- Withdrawal or secrecy from friends and family
- A low performance in studies
- Difficulty in sleeping
- Irritability or erratic mood
- loss of motivation
In comparison to adults with schizophrenia, teens may not have symptoms like delusions. But teens  might have visual hallucinations.

Causes

The real or exact cause of schizophrenia is not known. However, according to various researches and studies, a variety of factors like genetics, brain chemicals and external surroundings may lead to the  development of the mental disorder.

It is believed that difficulties associated with some naturally occurring brain chemicals, like neurotransmitters called dopamine and glutamate, may develop into schizophrenia. According to neuroimaging studies, there are visible differences in the chemical component and structure of brain and certain imbalances in the central nervous system of people diagnosed with schizophrenia. Though researchers are not sure whether these changes or differences are of any significance, yet they stress that schizophrenia is a brain disorder.

Risk factors

The exact cause of schizophrenia is unknown, but there are some factors that may increase the risk of developing or inhibiting this mental disorder called schizophrenia. They are as follows:

- A known family history of schizophrenia

- Heightened immune system activation, emanating from inflammation or autoimmune diseases

- very old age of the father

- Few pregnancy and birth related complications, like malnutrition or vulnerability to toxins or certain viruses that negatively affect brain development

- Certain cognitive (psychoactive or psychotropic) drugs taken during teenage and adolescence period

Complications

If not treated, schizophrenia can lead to serious problems that hamper the day to day life. Complications associated with schizophrenia may be as follows:

- Suicidal thoughts and attempts of suicide

- harming and injuring self

- Anxiety disorders

- Depressive nature

- Alcohol or harmful drug intake, excessive tobacco use

- obsessive-compulsive disorder (OCD)

- low attention span at school and in studies

- problems understanding legal and financial issues

- Social withdrawal

- Health and medical issues

- homelessness

- Feeling victimized

- Sporadic bursts of aggressive or bizarre behavior

Diagnosis

A proper diagnosis of schizophrenia will involve looking out for and ruling out any other mental state illness and determining whether symptoms are  due to drug abuse, excessive alcohol intake, substance abuse or any other health condition. Determining a diagnosis of schizophrenia may include:

- Physical diagnosis. This is necessary to find and rule out any other issues behind the occurrence of the said symptoms and to determine any near complications.

- Clinical Tests and exams. All such tests and screenings may be done to aid ruling out similar symptoms for other medical conditions and checking for alcohol and drug abuse. The physician may call out for an MRI or a CT scan.

- Psychiatric evaluation. A person with symptoms of schizophrenia  may be checked upon by a psychiatric or mental health professional for determining the mental order of the patient. The doctor will check the physical behavior and emotional conduct and discuss  the patient's thoughts, mental state, experiences of delusions, hallucinations, drug abuse, and chances of for aggressive moments or suicidal attempts. This even involves finding out family and personal history of similar conditions .

Treatment

Schizophrenia is a severe mental condition that necessities lifelong treatment, even though symptoms may subside. Medical attention and treatment coupled with psycho-social therapy can help keep the condition under control. In few cases, hospitalization might be necessary.

Treatment involves regular consultation with a psychiatrist having experience in dealing with  patients of schizophrenia . Apart from that, the patient will require a social worker, a psychiatric nurse and often a case manager to manage the overall treatment and care. Treatment of schizophrenia involves a full-fledged team approach with expert clinical experience.

Medication

No patient diagnosed with schizophrenia can be treated without medications. Most commonly, antipsychotic medications are prescribed. They are meant to control common symptoms by impacting the brain neurotransmitter dopamine. Medications for schizophrenia are known to have various  side effects, so patients of schizophrenia often refuse to take them. Often, there is reluctance to such medications and long-term treatment.

First-generation antipsychotics: TSuch antipsychotics are known to have frequent and highly significant neurological side effects that sometimes may lead to a motor disorder (tardive dyskinesia). This condition is non-reversible and dangerous. The most commonly prescribed first-generation antipsychotics include:

- Perphenazine

- Chlorpromazine

- Haloperidol

- Fluphenazine

Second-generation antipsychotics: These are comparitively newer and safer medications that are usually preferred by many doctors. They have lower risks and possibilities of side effects as compared to  first-generation antipsychotics. The common second-generation antipsychotics are:

- Asenapine (Saphris)

- Cariprazine (Vraylar)

- Iloperidone (Fanapt)

- Lurasidone (Latuda)

- Olanzapine (Zyprexa)

- Brexpiprazole (Rexulti)

- Quetiapine (Seroquel)

- Aripiprazole (Abilify)

- Ziprasidone (Geodon)

- Paliperidone (Invega)

- Risperidone (Risperdal)

Prevention

There is no sure formula to prevent schizophrenia, but continuing with the treatment can help manage and control the disease from worsening or aggravating. Apart from this, one can try and know the risk factors for schizophrenia to call for early diagnosis and treatment.

Myths

Myth 1: People with schizophrenia are harmful and dangerous to be around.

Fact: There may be times when people with schizophrenia act erratically or behave weird, but  generally very few are violent. Moreover, people undergoing treatment are less likely to be violent. If people with this mental disorder turn violent, it is because of an underlying condition, such as childhood behavior issues or substance abuse.

Myth 2: Lack of good parenting causes schizophrenia.

Fact: Schizophrenia is a brain related illness. It has unknown causes. Various factors like genes, tragedy-aftereffect, and drug abuse can trigger the disease. Parenting has nothing to do with the development of the disorder.

Myth 3: People with schizophrenia should be admitted in a mental hospital.

Fact: It is not true completely. There are a few cases where patients need to stay at a meental health facility. Commonly, patients of schizophrenia stay with family or in supportive facilities within the society.

Myth 4: A person can never recover from Schizophrenia.

Fact: Schizophrenia is a long term illness, but nothing is impossible. With proper treatment,  medications and psychiatric therapy, it is possible that around 25% of people suffering from the disorder will recover . Again, about 50% cases show improvement in their symptoms. With managed care, people with Schizophrenia can live fully normal lives.

Myth 5: Schizophrenia is like having a split personality.

Fact: This is the most common myth about schizophrenia. A split personality is a condition medically termed as Dissociative Identity Disorder or a Multiple Personality Disorder.  There are rare cases of MPD or DID. But, Schizophrenia is a cognitive illness, relating to the thinking ability of a person and is vastly different from the split personality disorder.

FAQs

Question 1: What are the different types of Schizophrenia?

Answer: The following are the different forms or types of schizophrenia:

- Paranoid schizophrenia

- Schizoaffective disorder

- Residual schizophrenia

- Disorganized schizophrenia

FAQ:

Question 2: Is Schizophrenia curable?

Answer: Not exactly. There is no permanent cure for schizophrenia but one can get treated for the same.  With proper care and treatment, psychiatric therapy and social rehabilitation, people with Schizophrenia can lead a fully normal life.

Question 3: Can substance abuse  cause Schizophrenia ?

Answer: Not known. Schizophrenia is a mental condition that is still under research and studies. The causes of it are not yet fully deciphered. There are a variety of factors including genetics, environment and other substance and drug abuse factors that can lead to the disorder. Some people  are born with problems in the brain chemicals, which can get accentuated or triggered by substance abuse.

Question 4: What is the future of people with the disorder?

Answer: Though significant developments have been made in research and studies on schizophrenia but still it is not clear why some patients have worsening symptoms than others;  why some patients do not recover fast and why some people fail to respond to the given treatment and medication. However, there are also positive results in many cases where people have responded well and recovered with the right treatment, rehabilitation, and social support and care.

Question 5: Are Schizophrenia Patients Depressed?

Answer: Depression is common in patients  with schizophrenia. In fact, depression is a primary effect that is seen in schizophrenic patients. About 80% of people with this mental disorder get notable depressive attacks.

Question 6: Are there any chances of relapse?

Answer: Medication can help control symptoms to an extent; however, there is no guarantee that a relapse will not occur. Though majority of the medications are known to lessen the occurrences of relapse by up to 80%. TO counterfeit, doctors prescribe secondary medications that are particularly meant to control depression, anxiety, or psychological attacks.

Question 7: Is there any therapy apart from medicinal treatment?

Answer: Yes, additional therapy is necessary . Support and counseling from family and society  works like psychotherapy. Sessions of psychotherapy usually stress the emotive and functional effects of the illness, and how the family and near ones can help in managing the illness. The therapy involves discussion over the signs and symptoms of the disorder, the nature of relapse, the role of sticking to medicines and the possible side-effects, recognizing and living with the symptoms, behavior with family members or colleagues, or continuing with a job or school. There are many programs designed specifically to address rehabilitation and practical abilities.

Question 8: Is it possible for a person with schizophrenia to lead a "normal" life?

Answer: If appropriate treatment, social rehabilitation, psychotherapy and adequate family support is provided, it is easier to manage and control symptoms in schizophrenic patients. There are many examples of people leading an independent life with families,  routine jobs, and social involvement.

Question 9: How to manage depressive symptoms in schizophrenic patients?

Answer: To help patients manage depressive symptoms of Schizophrenia, you can do the following:

- Mingle and involve with them rather than leaving them alone.

- Put them on an antidepressant drug after consulting with their doctor managing their disorder.

- Supplement their medication with proper nutritional diet.

- Help them engage in regular physical exercise.

- In cases of  severe depression, consult with their psychiatric for electroconvulsive therapy or transcranial magnetic stimulation.

Table of Content

About Fluphenazine
When is Fluphenazine prescribed?
What are the side effects of Fluphenazine?
Key highlights of Fluphenazine
Medicines containing Fluphenazine
What are the interactions for Fluphenazine?