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Cyproheptadine

Prescription vs.OTC: Prescription by Doctor required
Last Updated: October 22, 2020

Cyproheptadine is primarily prescribed for the tretament of Perennial and seasonal allergic rhinitis and other allergic symptoms including urticaria. The dosage is based on your age, weight, medical condition, body size and response to treatment.

Cyproheptadine is an antihistamine used to relieve allergy symptoms caused by seasonal allergies, food or blood such as watery eyes, sneezing, runny nose or itching eyes or nose. It works by blocking natural substances like serotonin and histamine that your body makes during an allergic reaction. It also treats mild, uncomplicated hives.

During treatment with this medicine, you may experience drowsiness, constipation, dizziness, blurred vision, or dry mouth, nose or throat as side effects. Some people may also experience serious side effects like mood changes, shaking, seizures, difficulty urinating and irregular heartbeat. A very serious allergic reaction to this drug is rarely seen.

This medicine is not prescribed for people who have an allergic reaction to it, women who are breast-feeding, a newborn baby or premature infant, an elderly person, those who have narrow-angle glaucoma, an enlarged prostate, a peptic ulcer or bladder, stomach, or bowel blockage.

If you are taking or have taken within the last 14 days a monoamine oxidase inhibitor, do not take this medicine. Keep your doctor informed about your medical conditions and other medications you are taking during this treatment.

Do not use in neonates, safety and efficacy have not been established in children <2 years of age; symptomatic prostate hypertrophy. Cyproheptadine are more likely to cause dizziness, excessive sedation, syncope, toxic confusion states, and hypotension in the elderly.

In case reports, Cyproheptadine has promoted weight gain in anorexic adults, though it has not been specifically studied in the elderly. All cases of weight loss or decreased appetite should be adequately assessed.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

This medicine is used to treat the following conditions:

  • Seasonal Allergic Rhinitis

  • Perennial Allergic Rhinitis

  • Other Allergic Conditions

  • Urticaria

  • Hypersensitivity

  • Narrow Angle Glaucoma

  • Bladder Neck Obstruction

  • Monoamine Oxidase (MAO) Inhibitors

Common side effects of this medicine are as follows:

  • Is It safe with alcohol?

    Cyproheptadine may cause excessive drowsiness and calmness with alcohol.
  • Are there any pregnancy warnings?

    Cyproheptadine is probably safe to use during pregnancy. Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
  • Are there any breast-feeding warnings?

    Cyproheptadine is probably unsafe to use during breastfeeding. Please consult your doctor.
  • Is it safe to drive while on this medicine?

    Caution is advised when driving or operating machinery.
  • Does this affect kidney function?

    Caution should be used in patients with impaired renal function.
  • Does this affect liver function?

    Dosage should be reduced in patients with significant hepatic dysfunction. Kindly consult your doctor.
  • What is the onset of action?

    The action of the medicine is initiated within 60 minutes after its administration.
  • How long is the duration of effect?

    The effect of this medicine will remain active for about 8 - 12 hours after its administration.
  • Are there any missed dose instructions?

    If you miss a dose of Cyproheptadine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Below is the list of medicines, which contains Cyproheptadine as ingredient

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The mechanism of action of the medicine remains uncertain at this point of time, even though some experiments have been performed on rats to determine the same.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Alcohol

    Alcohol causes an additive CNS effects, thus must be avoided while taking this medicine.
  • Interaction with Lab Test

    Following lab test might get a false report:
    • Diagnostic antigen skin tests
    • Amylases (S) get increased
    • Fasting glucose (S) get decreased.
  • Interaction with Medicine

    Increased toxicity: MAO inhibitors may lead to hallucinations.
  • Interaction with Disease

    • Do not use in neonates, safety and efficacy have not been established in children <2 years of age; symptomatic prostate hypertrophy; antihistamines are more likely to cause dizziness, excessive sedation, syncope, toxic confusion states, and hypotension in the elderly. In case reports, Cyproheptadine has promoted weight gain in anorexic adults, though it has not been specifically studied in the elderly. All cases of weight loss or decreased appetite should be adequately assessed.
    • Hypersensitivity to Cyproheptadine or any component; narrow-angle glaucoma, bladder neck obstruction, acute asthmatic attack, stenosing peptic ulcer, GI tract obstruction. Avoid use in premature and term newborns due to potential association with SIDS.

Ques: What is Cyproheptadine?

Ans: Cyproheptadine is an antihistamine that works blocking natural substances like serotonin and histamine in the body.

Ques: What are the uses of Cyproheptadine?

Ans: It is used to relieve allergy symptoms caused by seasonal allergies such as watery eyes, sneezing, runny nose or itching eyes or nose.

Ques: What are the side effects of Cyproheptadine?

Ans: Sleepiness is the most common side effect of this drug.

Ques: Is Cyproheptadine used to gain weight/for headaches?

Ans: No, this medication is only used to cure allergies. Patients should not take it for headache or weight issues.

Ques: Is Cyproheptadine a narcotic/antihistamine/anticholinergic/steroid?

Ans: Cyproheptadine comes under the classification of antihistaminic drugs. It is not a narcotic or steroid.

Ques: Is Cyproheptadine over the counter medicine?

Ans: No, this medication is only available with doctor's prescription.

Ques: Is Cyproheptadine safe?

Ans: The drug is completely safe, however make sure you consume it only in recommended doses.

Ques: Can I take Cyproheptadine with Benadryl/Tylenol/ibuprofen?

Ans: Avoid consuming them together as these drugs can interact with each other and might alter the effects of Cyproheptadine.

Ques: Does Cyproheptadine get you high/make you gain weight/increase appetite/make you hungry?

Ans: Cyproheptadine only causes sleepiness in some individuals. Other than this, no other side effects are reported as of now.

Ques: Does Cyproheptadine affect birth control?

Ans: Studies reveal that this medication does not affect birth control. However, consult a doctor and follow his/her advice on it.

Ques: Does Cyproheptadine have codeine/acetaminophen in it?

Ans: No, Cyproheptadine does not contain codeine/acetaminophen in it.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Table of Content
About Cyproheptadine
What are the uses of Cyproheptadine
What are the contraindications of Cyproheptadine ?
What are the side effects of Cyproheptadine ?
Key highlights of Cyproheptadine
What are the dosage instructions?
Medicines containing Cyproheptadine
How does this medication work?
What are the interactions of Cyproheptadine ?
FAQs about Cyproheptadine