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Claribid 500 MG Tablet

Manufacturer: Abbott Healthcare Pvt. Ltd
Medicine composition: Clarithromycin
Prescription vs.OTC: Prescription by Doctor not required
Last Updated: May 18, 2021

As a macrolide antibiotic, Claribid 500 MG Tablet is used in the treatment of infections caused by bacteria. The infections may include pneumonia, respiratory tract infections, lyme disease, strep throat, skin infections, H. pylori infection, among others.

Claribid 500 MG Tablet is also indicated for prophylaxis of bacterial endocarditis in patients who are allergic to penicillin and undergoing surgical or dental procedures.

It is categorised as a broad-spectrum antibiotic which protects against mycoplasma, chlamydia and mycobacteria and other gram-negative and gram-positive bacteria. It works by decreasing protein production of these bacteria. It is available in the form of tablets, pills and liquids.

Claribid 500 MG Tablet is indicated for the treatment of duodenal ulcer disease due to H. pylori in regimens with other drugs including amoxicillin and lansoprazole or omeprazole, ranitidine, bismuth citrate, bismuth subsalicylate, tetracycline and/or an H2-antagonist.

In children, for treatment of pharyngitis/tonsillitis, acute maxillary sinusitis, acute otitis media, uncomplicated skin/skin structure infections due to the above organisms; treatment of and prevention of disseminated mycobacterial infections due to M. avium complex disease (eg, patients with advanced HIV infection).

The amount your doctor prescribes and how long you take it depend on your age, medical condition and its severity and your reaction to the first dose.Take full course of therapy; do not discontinue without consulting prescriber.

Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake). You may experience nausea (small frequent meals, or sucking lozenges may help); abnormal taste (frequent mouth care or chewing gum may help); diarrhea, headache, or abdominal cramps (medication may be ordered).

Report persistent fever or chills, easy bruising or bleeding, or joint pain. Report severe persistent diarrhea, skin rash, sores in mouth, foul-smelling urine, rapid heartbeat or palpitations, or difficulty breathing. Do not refrigerate oral suspension (more palatable at room temperature).

Symptoms of overdose include nausea, vomiting, diarrhea, prostration, reversible pancreatitis, hearing loss with or without tinnitus or vertigo. Treatment includes symptomatic and supportive care.

This medication is used to treat the following problems:

  • Pharyngitis/Tonsillitis

  • Bronchitis

  • Pneumonia

  • Helicobacter Pylori Infection

  • Skin And Structure Infection

Side effects of this drug includes:

  • How long is the duration of effect?

    The effect of this medication lasts for an average duration of 9 to 21 hours for an Immediate release.
  • What is the onset of action?

    The peak effect of this medication can be observed in 2 to 3 hours for an immediate-release tablet and 5 to 8 hours for an extended-release tablet.
  • Are there any pregnancy warnings?

    This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.
  • Is it habit forming?

    No habit forming tendency has been reported.
  • Are there any breast-feeding warnings?

    This medication is not recommended for breastfeeding women unless absolutely necessary. Consult your doctor before using.
  • How long is the duration of effect?

    The effect of this medicine will remain active for about 10 - 12 hours.
  • What is the onset of action?

    The effect of this medicine will be initiated within 60 minutes after its administration.
  • Does this affect kidney function?

    Caution must be taken while using this in patients with kidney disease. Adjustment of dose might be needed. Usually, decreased doses or prolonged dosing intervals are recommended. Kindly consult your doctor before taking it.
  • Does this affect liver function?

    This medicine is probably safe to be used in patients with liver disease. Limited data is available in reference to this. Adjustment of dose might not be needed. Kindly consult your doctor before taking it.

Below is the list of medicines, which have the same composition, strength and form as Claribid 500 MG Tablet , and hence can be used as its substitute.

  • Are there any missed dose instructions?

    The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for your next dose.
  • Are there any overdose instructions?

    Seek emergency medical treatment or contact the doctor in case of an overdose.

This medication is a macrolide antibiotic that stops the growth of bacteria by inhibiting protein synthesis. It binds reversibly to the 50S ribosomal subunits which prevent peptidyl transferase activity which in turn interferes with the translocation process thus preventing peptide chain elongation.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Medicine

    • Claribid 500 MG Tablet increases serum theophylline levels by as much as 20%.
    • Increased concentration of HMG CoA-reductase inhibitors (lovastatin and simvastatin).
    • Amprenavir's serum concentration may be increased.
    • Significantly increases Claribid 500 MG Tablet levels and those of cyclosporine, digoxin, ergot alkaloid, tacrolimus, omeprazole and triazolam.
    • Peak levels (but not AUC) of zidovudine are often increased; terfenadine and astemizole should be avoided with use of Claribid 500 MG Tablet since plasma levels may be increased by >3 times; serious arrhythmias have occurred with cisapride and other drugs which inhibit cytochrome P-450 3A4 (eg, clarithromycin).
    • Fluconazole increases clarithromycin levels and AUC by ~25%; death has been reported with administration of pimozide and Claribid 500 MG Tablet. Concurrent use is contraindicated.
    Note: While other drug interactions (bromocriptine, disopyramide, lovastatin, phenytoin, and valproate) known to occur with erythromycin have not been reported in clinical trials with Claribid 500 MG Tablet, concurrent use of these drugs should be monitored closely.
  • Interaction with Disease

    In presence of severe renal impairment with or without coexisting hepatic impairment, decreased dosage or prolonged dosing interval may be appropriate; antibiotic-associated colitis has been reported with use of Claribid 500 MG Tablet; elderly patients have experienced increased incidents of adverse effects due to known age-related decreases in renal function.
  • Interaction with Food

    May be taken with or without meals; may be taken with milk; food delays absorption; total absorption remains unchanged.

Ques: What is claribid 500 mg tablet?

Ans: This medication belongs to the class of drugs knowns as Antibiotic, which is prescribed to the patients having Helicobacter pylori, Otitis Media and skin structure infections. It contains Clarithromycin as an active ingredient. This medication helps lower the risk of lung and stomach infections. It prevents stomach ulcers, susceptible staphylococcal and streptococcal skin infections.

Ques: What are the uses of claribid 500 mg tablet?

Ans: This medication is used for the treatment and prevention from conditions and symptoms of Pharyngitis and tonsillitis, It helps to reduce the inflammation caused by bacteria of Streptococcus pneumoniae, Haemophilus influenzae, and Mycoplasma pneumonia.

Ques: What are the Side Effects of claribid 500 mg tablet?

Ans: This is a list of possible side-effects which may occur due to the constituting ingredients of this medication. These include vomiting, diarrhea, headache, abdominal pain, weakness, dizziness, excessive gas in the stomach and heartburn.

Ques: What are the instructions for storage and disposal claribid 500 mg tablet?

Ans: This medication should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MBBS, Master in Healthcare Administration, Diploma in Occupational Health
General Physician
Table of Content
About Claribid 500 MG Tablet
What are the uses of Claribid 500 MG Tablet
What are the contraindications of Claribid 500 MG Tablet ?
What are the side effects of Claribid 500 MG Tablet ?
Key highlights of Claribid 500 MG Tablet
What are the substitutes for Claribid 500 MG Tablet ?
What are the dosage instructions?
How does this medication work?
What are the interactions of Claribid 500 MG Tablet ?
FAQs about Claribid 500 MG Tablet