Lybrate Logo
Get the App
For Doctors
Login/Sign-up
tab_logos
About
tab_logos
Feed
Overview

Clarian 1% Gel

Manufacturer :  Organic Laboratories
Medicine Composition :  Clarithromycin
Prescription vs OTC : Prescription by Doctor required

About Clarian 1% Gel

As a macrolide antibiotic, Clarithromycin is used in the treatment of infections caused by bacteria. The infections may include pneumonia, respiratory tract infections, lyme disease, strep throat, skin infections, H. pylori infection, among others.

Clarian 1% Gel is also indicated for prophylaxis of bacterial endocarditis in patients who are allergic to penicillin and undergoing surgical or dental procedures.

It is categorised as a broad-spectrum antibiotic which protects against mycoplasma, chlamydia and mycobacteria and other gram-negative and gram-positive bacteria. It works by decreasing protein production of these bacteria. It is available in the form of tablets, pills and liquids.

Clarian 1% Gel is indicated for the treatment of duodenal ulcer disease due to H. pylori in regimens with other drugs including amoxicillin and lansoprazole or omeprazole, ranitidine, bismuth citrate, bismuth subsalicylate, tetracycline and/or an H2-antagonist.

In children, for treatment of pharyngitis/tonsillitis, acute maxillary sinusitis, acute otitis media, uncomplicated skin/skin structure infections due to the above organisms; treatment of and prevention of disseminated mycobacterial infections due to M. avium complex disease (eg, patients with advanced HIV infection).

The amount your doctor prescribes and how long you take it depend on your age, medical condition and its severity and your reaction to the first dose.Take full course of therapy; do not discontinue without consulting prescriber.

Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake). You may experience nausea (small frequent meals, or sucking lozenges may help); abnormal taste (frequent mouth care or chewing gum may help); diarrhea, headache, or abdominal cramps (medication may be ordered).

Report persistent fever or chills, easy bruising or bleeding, or joint pain. Report severe persistent diarrhea, skin rash, sores in mouth, foul-smelling urine, rapid heartbeat or palpitations, or difficulty breathing. Do not refrigerate oral suspension (more palatable at room temperature).

Symptoms of overdose include nausea, vomiting, diarrhea, prostration, reversible pancreatitis, hearing loss with or without tinnitus or vertigo. Treatment includes symptomatic and supportive care.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the uses of Clarian 1% Gel

    • Pharyngitis/Tonsillitis

    • Bronchitis

    • Pneumonia

    • Helicobacter Pylori Infection

    • Skin And Structure Infection

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the contraindications of Clarian 1% Gel ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the side effects of Clarian 1% Gel ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Key highlights of Clarian 1% Gel

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 9 to 21 hours for an Immediate release.

    • What is the onset of action?

      The peak effect of this drug can be observed in 2 to 3 hours for an immediate release tablet and 5 to 8 hours for an extended release tablet.

    • Are there any pregnancy warnings?

      This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Are there any breast-feeding warnings?

      Women who are breastfeeding must consult doctor before using this drug.

    • What is the onset of action?

      The effect of this medicine will be initiated within 60 minutes after its administration.

    • How long is the duration of effect?

      The effect of this medicine will remain active for about 10 - 12 hours.

    • Does this affect kidney function?

      Caution must be taken while using this in patients with kidney disease. Adjustment of dose might be needed. Usually, decreased doses or prolonged dosing intervals are recommended. Kindly consult your doctor before taking it.

    • Does this affect liver function?

      This medicine is probably safe to be used in patients with liver disease. Limited data is available in reference to this. Adjustment of dose might not be needed. Kindly consult your doctor before taking it.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the substitutes for Clarian 1% Gel ?

    Below is the list of medicines, which have the same composition, strength and form as Clarian 1% Gel , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for your next dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Where is the Clarian 1% Gel approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    How does this medication work?

    Clarian 1% Gel is a macrolide antibiotic that stops the growth of bacteria by inhibiting protein synthesis. It binds reversibly to the 50S ribosomal subunits which prevent peptidyl transferase activity which in turn interferes with the translocation process thus preventing peptide chain elongation.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

      What are the interactions of Clarian 1% Gel ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Information not available.
      • Interaction with Medicine

        • Clarithromycin increases serum theophylline levels by as much as 20%.
        • Increased concentration of HMG CoA-reductase inhibitors (lovastatin and simvastatin).
        • Amprenavir's serum concentration may be increased.
        • Significantly increases carbamazepine levels and those of cyclosporine, digoxin, ergot alkaloid, tacrolimus, omeprazole and triazolam.
        • Peak levels (but not AUC) of zidovudine are often increased; terfenadine and astemizole should be avoided with use of clarithromycin since plasma levels may be increased by >3 times; serious arrhythmias have occurred with cisapride and other drugs which inhibit cytochrome P-450 3A4 (eg, clarithromycin).
        • Fluconazole increases clarithromycin levels and AUC by ~25%; death has been reported with administration of pimozide and clarithromycin. Concurrent use is contraindicated.
        Note: While other drug interactions (bromocriptine, disopyramide, lovastatin, phenytoin, and valproate) known to occur with erythromycin have not been reported in clinical trials with clarithromycin, concurrent use of these drugs should be monitored closely.
      • Interaction with Food

        May be taken with or without meals; may be taken with milk; food delays absorption; total absorption remains unchanged.
      • Interaction with Disease

        In presence of severe renal impairment with or without coexisting hepatic impairment, decreased dosage or prolonged dosing interval may be appropriate; antibiotic-associated colitis has been reported with use of clarithromycin; elderly patients have experienced increased incidents of adverse effects due to known age-related decreases in renal function

      FAQs about Clarian 1% Gel

      • Ques : What is Clarian 1% Gel?

        Ans : Clarian 1% Gel is a macrolide antibiotic.

      • Ques : What are the uses of the Clarian 1% Gel?

        Ans : Clarian 1% Gel is used in the treatment of infections caused by bacteria.

      • Ques : How long do I need to use Clarian 1% Gel before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : At what frequency do I need to use Clarian 1% Gel?

        Ans : This medication should be taken in the dosage as prescribed by the doctor.

      • Ques : Should I use Clarian 1% Gel empty stomach, before food or after food?

        Ans : This medication should be taken after food in a prescribed dosage.

      • Ques : What are the instructions for the storage and disposal of Clarian 1% Gel?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      • Ques : How long does Clarian 1% Gel take to work?

        Ans : Usually, Clarian 1% Gel starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.

      • Ques : What if I don't get better after using Clarian 1% Gel?

        Ans : Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.

      • Ques : Can the use of Clarian 1% Gel cause diarrhea?

        Ans : Yes, the use of Clarian 1% Gel can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If you are experiencing severe diarrhea, talk to your doctor about it.

      • Ques : Can the use of Clarian 1% Gel cause infertility?

        Ans : There is no firm evidence to suggest that the use of Clarian 1% Gel will cause infertility in males or females.

      References

      • Clarithromycin-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 27 May 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/clarithromycin

      • Clarithromycin-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 27 May 2022].Available from:

        https://go.drugbank.com/drugs/DB01211

      • CLARITHROMYCIN gel,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 27 May 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=CLARITHROMYCIN

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
      swan-banner
      Sponsored

      Popular Questions & Answers

      View All

      Is clarithromycin good for stomach ulcer. How t...

      related_content_doctor

      Dr. Prakhar Singh

      General Physician

      Stomach ulcers are usually caused by helicobacter pylori bacteria or non-steroidal anti-inflammat...

      Could anyone tell me which ointment is much eff...

      related_content_doctor

      Dr. Sajeev Kumar

      General Physician

      For fungal infection candid cream is useful . These Fucidin H cream, clarithromycin or imiquimod ...

      Hi I am suffering from cough and throat infecti...

      related_content_doctor

      Dr. Jayvirsinh Chauhan

      Homeopath

      Hello Lybrate-User, No, it is not right medicine. It has many side effects. You should take homoe...

      I used clarithromycin esomeprazole amoxicillin ...

      related_content_doctor

      Dr. Karuna Chawla

      Homeopathy Doctor

      Bitter taste can be because of infection. Take home cooked, fresh light food. Drink boiled water....

      I have been diagnosed with folliculitis on my f...

      related_content_doctor

      Dr. Sandesh Gupta

      Dermatologist

      Drink lots of water. Tab azifast 500mg three days in a week. Nadoxin gel morning. Clear gel in ni...

      Table of content

      Content Details
      Profile Image
      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
      Profile Image
      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
      chat_icon

      Ask a free question

      Get FREE multiple opinions from Doctors

      posted anonymously
      swan-banner