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Clarian 1% Gel

Manufacturer: Organic Laboratories
Medicine composition: Clarithromycin
Prescription vs.OTC: Prescription by Doctor required
Last Updated: December 14, 2018

A macrolide antibiotic, Clarian 1% Gel is used in the treatment of infections caused by bacteria. The infections may include pneumonia, respiratory tract infections, lyme disease, strep throat, skin infections, H. pylori infection, among others. It is categorised as an broad-spectrum antibiotic which protects against mycoplasma, chlamydia and mycobacteria and other gram-negative and gram-positive bacteria. It works by decreasing protein production of these bacteria. It is available in the form of tablets, pills and liquids.

Common side effects of Clarian 1% Gel may include diarrhoea, stomach pain, nausea, abnormal taste in mouth, headache and vomiting. In mild cases, these effects go away within a few days or a couple of weeks. Severe allergic reactions are very rare.

Ensure to never take Clarian 1% Gel if –

  • You are allergic to Clarian 1% Gel or similar antibiotics.
  • You are suffering from heart rhythm disorder and have a history of long QT syndrome(Long QT syndrome refers to a heart rhythm disorder that can potentially cause rapid heartbeats, irregular heart rhythms and even dealth).
  • You have kidney or liver problems.

Medicines like cisapride, primozide, ergotamine and lovastain cause life-threatening interactions with Clarian 1% Gel and therefore should not be taken without consulting a doctor.Clarian 1% Gel should not be used during pregnancy except in cases where no alternative medication is available as it may potentially cause harm to the foetus. This drug enters breast milk in mild quantities which usually does not affect the infant. However, let your doctor know if you are breastfeeding.

The amount your doctor prescribes and how long you take it depend on your age, medical condition and its severity and your reaction to the first dose.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Internal Medicine Specialist before using this medicine.

Tonsilitis/Pharyngitis

Clarian 1% Gel is used in the treatment of Tonsilitis/Pharyngitis caused by Streptococcus pneumoniae, Haemophillus influenzae and some fungal infections.
Clarian 1% Gel is used in the treatment of Bronchitis which is an inflammation in lungs caused by Streptococcus pneumoniae, Haemophilus influenzae, and some Mycoplasma pneumoniae.
Clarian 1% Gel is used in the treatment of Pneumonia which is a common type of lung infection caused by Streptococcus pneumoniae and Haemophilus influenzae.

Helicobacter pylori Infection

Clarian 1% Gel is used in the treatment of the infection of the stomach characterized by ulcers. It is caused by helicobacter pylori bacteria.

Skin and Structure Infection

Clarian 1% Gel is used to treat skin and structure infections caused by Staphylococcus aureus and Streptococcus pyogenes.
Avoid taking this medicine if you have a known allergy to it or any other macrolides.

Impaired Liver function

Clarian 1% Gel is not recommended in the patients with the history of any liver injury.
In addition to its intended effect, Clarian 1% Gel may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Fever or chills

Major Less Common

Lower back pain

Major Less Common

Abdominal pain

Major Rare

Nausea or Vomiting

Major Rare

Diarrhea

Major Rare

Skin Rash

Major Rare

Acid or sour stomach

Minor Less Common

Excessive air or gas in stomach

Minor Less Common

Headache

Minor Less Common

Heartburn

Minor Less Common

How long is the duration of effect?

The effect of this medicine lasts for an average duration of 9 to 21 hours for an Immediate release.

What is the onset of action?

The peak effect of this medicine can be observed in 2 to 3 hours for an immediate release tablet and 5 to 8 hours for an extended release tablet.

Are there any pregnancy warnings?

This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

Is it habit forming?

No habit forming tendency has been reported.

Are there any breast-feeding warnings?

This medicine is not recommended for breastfeeding women unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine. Monitoring of undesired effects like diarrhea, candidiasis (thrush, diaper rash) is necessary.
Below is the list of medicines, which have the same composition, strength and form as Clarian 1% Gel , and hence can be used as its substitute.
Ranbaxy Laboratories Ltd

Missed Dose instructions

The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for your next dose.

Overdose instructions

Seek emergency medical treatment or contact the doctor in case of an overdose.

India

United States

Japan

Clarian 1% Gel is a macrolide antibiotic that stops the growth of bacteria by inhibiting protein synthesis. It binds reversibly to the 50S ribosomal subunits which prevent peptidyl transferase activity which in turn interferes with the translocation process thus preventing peptide chain elongation.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

Interaction with Disease

QT Prolongation

Major
Inform your doctor if you have arrhythmia, any heart disease or drugs that prolong QT interval such as psychiatric drugs and anti-arrhythmic drugs.

Colitis

Moderate
Avoid taking Clarian 1% Gel if you experience severe diarrhea, abdominal pain, and blood in stools after taking the medicine. Inform the doctor if you have any gastrointestinal diseases. Drink adequate amount of water to prevent dehydration.

Interaction with Alcohol

Alcohol

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Lab Test

Lab

Information not available.

Interaction with Food

Food

Information not available.

Interaction with Medicine

Clonazepam

Moderate
Clarian 1% Gel may increase the blood levels of clonazepam. Any symptoms of drowsiness, anxiety and breathing difficulties should be reported to the doctor. Operating heavy machinery or driving a vehicle should be avoided. Dose adjustments or an alternate medicine should be considered based on the clinical condition.

Amiodarone

Major
Combined use of these medicines may increase the risk of irregular heartbeats and also may increase the blood levels of amiodarone. Any symptoms of dizziness, lightheadedness, fast heartbeats should be reported to the doctor. An alternate medicine should be considered based on the clinical condition.

Ethinyl Estradiol

Moderate
The desired effect of contraceptive pills will not be achieved if these medicines are taken together. Appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.

Atorvastatin

Major
Clarian 1% Gel may increase the levels of atorvastatin and may cause serious muscle injury and kidney injury. Any symptoms of dark colored urine, swelling of limbs, joint pain should be reported to the doctor. An alternate medicine should be considered based on the clinical condition.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Table of Content
About Clarian 1% Gel
What are the uses of Clarian 1% Gel
What are the contraindications of Clarian 1% Gel ?
What are the side effects of Clarian 1% Gel ?
Key highlights of Clarian 1% Gel
What are the substitutes for Clarian 1% Gel ?
What are the dosage instructions?
Where is the Clarian 1% Gel approved?
How does medicine works?
What are the interactions of Clarian 1% Gel ?