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Cimetidine

Prescription vs.OTC: Prescription by Doctor required

Stomach and intestine ulcers can be effectively treated with Cimetidine. The medication also helps prevent the recurrance of ulcers, throat and stomach problems that occur because of excess acid present in the stomach. GERD can also be treated with Cimetidine. The drug reduces the extra acid present in the stomach, thus reducing symptoms like stomach pain, heart burn, constant cough, and sleep problems. The drug also protects or digestive tract from serious damage because of the acid present.

Cimetidine is a part of a group of drugs known as H2 blockers. The drug is also available over the counter as it is commonly taken by individuals who suffer from heartburn.

You can take the drug orally, as per the directions of your doctor or pharmacist. The dosage of the drug and the time period for which it should be taken generally depends on the severity of your condition and your body’s response to it.

Side effects commonly occur in case of most medicines. Most patients experience very minor side effects which go away with time. Only a few suffer from a severe allergic reaction or any major problems. Symptoms of an allergic reaction may include rashes, itching, problems with breathing and swelling of the face, throat and tongue. Some of the common side effects that you may experience are headache, diarrhea, and dizziness. Some serious side effects that you may experience are hallucinations, depression, confusion, problems with urinations etc. It is best that you consult your doctor if you experience any major side effects.

The drug should not be taken for more than a fortnight without consulting your doctor first. Moreover, ensure that you take only 2 doses in a span of 24 hours.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Gastroenterologist before using this medicine.

Duodenal Ulcer
Cimetidine is used in the treatment of ulcers in the small intestine.
Gastric Ulcer
Cimetidine is used in the treatment of ulcers in the stomach.
Gastroesophagal Reflux Disease
Cimetidine is used for the treatment of a condition where the acid produced in the stomach causes irritation in the food pipe.
Zollinger-Ellison Syndrome
Cimetidine is used to relieve the symptoms of this rare condition where the acid secretion in the stomach is abnormally high.
Not recommended in patients with known allergy to Cimetidine or other H2 antagonists.
In addition to its intended effect, Cimetidine may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Headache Major Common
Dizziness Major Common
Diarrhea Major Common
Gynecomastia Major Rare
Decrease in blood cell count Major Rare
Skin rash Minor Common
Muscle pain Minor Common
Sleepiness Minor Common
Joint pain Minor Common
How long is the duration of effect?
The effect of this medicine lasts for an average duration of 4 to 5 hours after an intravenous dose and 4 to 8 hours after an oral dose.
What is the onset of action?
The effect of this medicine can be observed in less than 1 hour after an oral dose and less than 30 minutes after an intravenous dose.
Are there any pregnancy warnings?
This medicine is recommended in pregnant women only if benefits overweigh the risks.
Is it habit forming?
No habit forming tendencies were reported.
Are there any breast-feeding warnings?
This medicine is known to excreted through the breastmilk. It is not recommended for breastfeeding women.
Missed Dose instructions
Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose, then the missed dose can be skipped.
Overdose instructions
Seek emergency medical treatment or contact the doctor in case of an overdose.
India
United States
Japan
Cimetidine works as a histamine H2-receptor antagonist by binding to and inhibiting histamine receptors. This blocks histamine’s ability to induce suppressor T lymphocyte activities and to block natural killer cell activity and interleukin-2 production.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Disease
Gastro-intestinal bleeding Major
Use of Cimetidine is not recommended for use if any symptoms indicating gastrointestinal bleeding exists. Consult your doctor if there is blood in vomit or the stools are bloody or black.
Interaction with Alcohol
Alcohol Minor
Consumption of alcohol is not recommended in patients receiving Cimetidine. Any symptoms of adverse effects like dizziness, breathing difficulty should be reported to the doctor. Performing activities that require mental alertness like driving, operating machinery should be avoided.
Interaction with Lab Test
Lab
Information not available.
Interaction with Food
Food
Information not available.
Interaction with Medicine
Glipizide Moderate
Cimetidine may increase the effect of antidiabetics medicines like glipizide, glimepiride which may lower the blood glucose levels. Monitoring of blood glucose levels is necessary. Any symptoms like dizziness, tiredness, weakness should be reported to the doctor. Dose adjustments or an alternate medicine should be considered based on the clinical condition.
Loperamide Major
Cimetidine may increase the concentration of loperamide and may cause dizziness, lightheadedness, irregular heart rhythm, and difficulty of breathing. Inform the doctor if you are receiving either of the medications. Dose adjustments or an alternate class of medicine should be considered based on the clinical condition.
Phenytoin Major
Cimetidine may increase the concentration of phenytoin and may cause twitching eye movements, slurred speech, tremor, fainting, and breathing difficulty. Inform the doctor if you are receiving either of the medications. An alternate class of medicine should be considered based on the clinical condition.
Antifungal agents Moderate
Cimetidine will decrease the effect of antifungals, therefore inform the doctor if you are receiving any antifungals or gastric medications. Immediate medical treatment should be initiated if any symptoms of an increase in the severity of fungal infection appear. An alternate medicine should be considered based on the clinical condition.
What are you using Cimetidine for?
Other
Gastroesophagal Reflux Disease
Gastric Ulcer
How much was the improvement?
Average
Excellent
How long did it take before seeing improvement?
Within 2 days
Within 6 hours
More than 2 days
How frequently did you take this medicine?
Twice a day
How did you take this medicine?
Empty stomach
With Food
What were the side effects of this medicine?
Dizziness
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

I have molluscum on my pubic area. Can I use Imiquimod (Nilwart, imiquad), Cimetidine (Cimetin, gramocef-CV, Lock-2, Tymidin, Ulcibem)? Is any specific medicine available in India to treat this infection? Thanks.

BHMS
Homeopath, Thane
I have molluscum on my pubic area. Can I use Imiquimod (Nilwart, imiquad), Cimetidine (Cimetin, gramocef-CV, Lock-2, ...
Hi, molluscum can be treated with homoeopathy. Don't use any of allopathic medicines. Acid nit 30 4pills to be sucked thrice a day for 30 days revert back. Don't apply any creams.

Please prescribe medication to lower / maintain my creatinine levels which at present is 1.17 mg/dl thanks.

C.S.C, D.C.H, M.B.B.S
General Physician, Alappuzha
Please prescribe medication to lower / maintain my creatinine levels which at present is 1.17 mg/dl thanks.
The antibiotic trimethoprim-sulfamethoxazole and the H2-blocker cimetidine are 2 commonly used drugs that decrease the secretion of creatinine. This can result in a self-limited and reversible increase in the serum creatinine level of as much as 0.4 to 0.5 mg/dL (depending on baseline serum creatinine level).

Hi sir,my friend aged 25years having Gynecomastia consulted laproscopic surgeon and advised for Prolactin,FSH,Testosterone,TSH and laboratory reports were found to be normal,and if it is not harmonal problem then what could it be?is there any medication for this?suggest for appropriate treatment.. waiting for ur reply.....thanking you

MNAMS (Membership of the National Academy) (General Surgery) , MCh - Plastic and Reconstructive Surgery, DNB (Plastic Surgery)
Cosmetic/Plastic Surgeon,
Gynaecomastia is normal sometimes in puberty,but persistence of abnormal breast tissue in adult male can be due to a lot of clinical conditions klienfelter syndrome,lymphomas,luekemias,estrogen excess,and side effects of drugs like digitalis,inh,spiranolactone,cimetidine,ranitidine,oestrogens.You need examination by doctors and rule out any pathology,if everything is normal then liposuction can give excellent results.I have treated many patients successfully. www.plasticsurgeryindia.net
1 person found this helpful

I am male 31 year old I am suffering erectile dysfunction and early ejaculation. What should I do?

MD, DNB, FIDP, FIL
Dermatologist, Mumbai
In some cases, simple lifestyle changes, such as losing weight, drinking less alcohol, or quitting smoking, may improve erectile dysfunction. If the erectile dysfunction is caused by a certain medication, your doctor may suggest reducing the dose or trying an alternative drug. Certain blood pressure medications, allergy drugs, antidepressants, sedatives, appetite suppressants, and an ulcer drug called cimetidine may make it hard for a man to get a firm erection. Most men with erectile dysfunction, however, will need further treatment. Treatment options for erectile dysfunction include: psychotherapy (counseling) medications (drug therapy) vacuum devices (pumps) surgery
3 people found this helpful

I am 37 years old male, suffering from small penis and pre mature ejaculation problem, we are planning for a baby, how can I get complete solution?

MD, DNB, FIDP, FIL
Dermatologist, Mumbai
In some cases, simple lifestyle changes, such as losing weight, drinking less alcohol, or quitting smoking, may improve erectile dysfunction. If the erectile dysfunction is caused by a certain medication, your doctor may suggest reducing the dose or trying an alternative drug. Certain blood pressure medications, allergy drugs, antidepressants, sedatives, appetite suppressants, and an ulcer drug called cimetidine may make it hard for a man to get a firm erection. Most men with erectile dysfunction, however, will need further treatment. Treatment options for erectile dysfunction include: psychotherapy (counseling) medications (drug therapy) vacuum devices (pumps) surgery
2 people found this helpful

Popular Health Tips

Hives (Urticaria)!

MBBS, DHMS-Harvard, Masters in Clinical Dermatology
Dermatologist, Chandigarh
Hives (Urticaria)!

 

Hives (urticaria), also known as welts, is a common skin condition with itchy, pink to red bumps that appear and disappear anywhere on the body. An individual lesion of hives typically lasts a few hours before fading away, and new hives can appear as older areas disappear.

Hives can be triggered by many things, including:

  • Medications
  • Infections with viruses, bacteria, or fungi
  • Environmental allergies such as insect bites, pollen, mold, or animal dander
  • Physical exposures such as heat, cold, water, sunlight, or pressure
  • A medical condition such as gland diseases, blood diseases, or cancer
  • Food allergies, such as strawberries, eggs, nuts, or shellfish
  • Stress.

Signs and Symptoms-

  • Hives can affect any skin surface.
  • Hives are usually an itchy rash that can also burn or sting

Self-Care Guidelines-

If you are experiencing mild hives, you might

  • Take cool showers
  • Apply cool compresses
  • Wear loose-fitting clothes
  • Avoid strenuous activity
  • Use an over-the-counter antihistamine such as diphenhydramine or loratadine

When to Seek Medical Care-

If your child's hives make it difficult to breathe or swallow or if your child feels lightheaded, call an ambulance.
In other, non-urgent, situations, see your doctor if the hives do not improve with treatment or if they continue to appear for more than a few days.

Treatments Your Physician May Prescribe-

After confirming that you have hives, the doctor will work with you to discover the possible cause. The doctor will take a detailed medical history and may do blood tests, urine tests, or X-rays.
Obviously, the best treatment for hives is to discover any triggers and stop your exposure to them. However, most people with hives do not know the cause, and they require medications to get rid of the hives.

The most common medications for hives include:

  • Sleep-causing (sedating) type-1 antihistamines such as diphenhydramine, hydroxyzine, or cetirizine
  • Non-sleep-causing (non-sedating) type-1 antihistamines such as loratadine, fexofenadine, or desloratadine
  • Type-2 antihistamines such as anitidine, cimetidine, or famotidine
  • Doxepin
  • Montelukast, zafirlukast, or zileuton

In rare situations, the doctor might prescribe a short course of oral corticosteroid pills.

13 people found this helpful

GERD: Causes, Symptoms and Treatment

MBBS, M.S. (Gold Medalist), MCh - Surgical Gastroenterology/G.I. Surgery
Gastroenterologist, Agra
GERD: Causes, Symptoms and Treatment

Gastroesophageal Reflux Disease (GERD) is a form of digestive disorder, which affects the lower oesophageal sphincters or the muscle ring present between the stomach and the food pipe. GERD incorporates the return of the contents of the stomach back to the oesophagus or food pipe. The functioning of the lower oesophageal sphincter is disrupted.

Causes:  Hiatal hernia is a common cause of GERD. An unhealthy lifestyle and diet may also lead to GERD. Intake of an excess amount of chocolates, fried food, coffee or alcohol triggers the chance of a reflux. GERD also occurs in obese people and pregnant women.

Symptoms: Heartburn, also known as acid indigestion, is the primary symptom of GERD. The affected person may feel a burning chest pain which starts from behind the breastbone and reaches up to the throat. The feeling can be defined as food coming back to the throat with a bitter, acidic taste. The burning sensation may last as long as two hours.

Other symptoms include:

  1. Excess saliva secretion
  2. Chronic conditions of sore throat
  3. Laryngitis
  4. Gum inflammation
  5. Tooth cavities
  6. Unpleasant breath

In order to diagnose GERD, several tests may be conducted . They are:

  1. An X-Ray of the upper part of the digestive system.
  2. Endoscopy to examine the inner part of the oesophagus.
  3. Ambulatory acid test for monitoring the amount of acid within the oesophagus.
  4. An oesophageal impedance test to measure substance movement inside the oesophagus.

Treatment

  1. A person must make several changes to his daily lifestyle and diet plan for treatment of GERD.
  2. Food and beverages like chocolates, fatty food, coffee, alcohol and peppermint should be avoided in order to reduce the weakening of the lower oesophageal sphincter. Several food items irritate the damaged oesophageal lining and should also be avoided. They include citrus fruits, tomato and pepper.
  3. Smoking cigarettes results in weakening of the lower oesophageal sphincter and should be stopped to reduce GERD.
  4. One should elevate the head of the bed on which he or she sleeps on blocks measuring 6 inches. This reduces the heartburn as gravity minimizes stomach reflux to return to the oesophagus.
  5. Over the counter medicines can be used to cure GERD. Antacids are a good example and neutralize the acid in the oesophagus and stomach, reducing heartburn. Combining antacids with foaming agents is also effective. A foam barrier is formed over the stomach, preventing the occurrence of acid reflux.
  6. Medicines for reducing acid in the stomach are prescribed in cases of chronic GERD, which include H2 blockers by the likes of cimetidine, famotidine or nizatidine.

GERD is a digestive disorder, which causes disruption in digestion, as reflux from the stomach is returned to the oesophagus. Proper treatment measures should be taken. If you wish to discuss about any specific problem, you can consult a Gastroenterologist.

3227 people found this helpful

Gastroesophageal Reflux Disease (GERD) - 6 Ways It Can Be Treated!

MBBS, MD - General Medicine, DM - Gastroenterology
Gastroenterologist, Delhi
Gastroesophageal Reflux Disease (GERD) - 6 Ways It Can Be Treated!

Gastroesophageal Reflux Disease (GERD) is a form of digestive disorder, which affects the lower oesophageal sphincters or the muscle ring present between the stomach and the food pipe. GERD incorporates the return of the contents of the stomach back to the oesophagus or food pipe. The functioning of the lower oesophageal sphincter is disrupted.

Causes

Hiatal hernia is a common cause of GERD. An unhealthy lifestyle and diet may also lead to GERD. Intake of an excess amount of chocolates, fried food, coffee or alcohol triggers the chance of a reflux. GERD also occurs in obese people and pregnant women.

Symptoms

Heartburn, also known as acid indigestion, is the primary symptom of GERD. The affected person may feel a burning chest pain which starts from behind the breastbone and reaches up to the throat. The feeling can be defined as food coming back to the throat with a bitter, acidic taste. The burning sensation may last as long as two hours.

Other symptoms include:

  1. Excess saliva secretion
  2. Chronic conditions of sore throat
  3. Laryngitis
  4. Gum inflammation
  5. Tooth cavities
  6. Unpleasant breath

In order to diagnose GERD, several tests may be conducted

  1. An X-Ray of the upper part of the digestive system.
  2. Endoscopy to examine the inner part of the oesophagus.
  3. Ambulatory acid test for monitoring the amount of acid within the oesophagus.
  4. An oesophageal impedance test to measure substance movement inside the oesophagus.

Treatment

  1. A person must make several changes to his daily lifestyle and diet plan for treatment of GERD.
  2. Food and beverages like chocolates, fatty food, coffee, alcohol and peppermint should be avoided in order to reduce the weakening of the lower oesophageal sphincter. Several food items irritate the damaged oesophageal lining and should also be avoided. They include citrus fruits, tomato and pepper.
  3. Smoking cigarettes results in weakening of the lower oesophageal sphincter and should be stopped to reduce GERD.
  4. One should elevate the head of the bed on which he or she sleeps on blocks measuring 6 inches. This reduces the heartburn as gravity minimizes stomach reflux to return to the oesophagus.
  5. Over the counter medicines can be used to cure GERD. Antacids are a good example and neutralize the acid in the oesophagus and stomach, reducing heartburn. Combining antacids with foaming agents is also effective. A foam barrier is formed over the stomach, preventing the occurrence of acid reflux.
  6. Proton pump inhibitors commonly called PPI are best drugs for control of symptoms. Occasionally prokinetic drugs are also used in combination with PPI.

Medicines for reducing acid in the stomach are prescribed in cases of chronic GERD, which include H2 blockers by the likes of cimetidine, famotidine or nizatidine. GERD is a digestive disorder which causes disruption in digestion, as reflux from the stomach is returned to the oesophagus. Proper treatment measures should be taken. If you wish to discuss about any specific problem, you can consult a doctor.

2005 people found this helpful

Tips On Preconception Health For Men

MBBS, DGO, MD, Fellowship in Gynae Oncology
Gynaecologist, Delhi
Tips On Preconception Health For Men

As couples prepare for pregnancy, it is easy to focus only on the woman's health. However, there are several habits men need to be forming during these critical months of preparation too. Issues of fertility do not rest solely on the female.

'agents that may cause birth defects do not reach the developing fetus through the father as they do from the pregnant mother,' but we do know that male exposure to certain substances can lead to some preliminary problems with fertility and also slightly elevate the risk of certain birth defects.

Male infertility alone accounts for approximately 1/3 of all infertility cases. Should fertility issues arise, you should plan ahead to be in the best physical condition to conceive.

Clean out the medicine cabinet

Eliminate as many medications from your routine as possible. Talk with your physician about your prescription medications. You may need to discontinue use or try something new.

The following medications have been known to impact male fertility:
 

  • Tagamet (cimetidine), sulfasalazine, and nitrofurantoin are used to treat ulcers, gastrointestinal problems, and urinary tract infections. These medications may impact sperm production and sperm count.
  • Steroids, such as prednisone and cortisone, which are used to treat asthma, arthritis and skin conditions, impact male fertility.
  • Chemotherapy and radiation could cause sterility or a significant change in sperm quality and quantity.



Take a good look at your work environment

Your work environment may be a contributing factor to your fertility. Ongoing exposure to certain agents such as pesticides, chemical fertilizers, lead, nickel, mercury, chromium, ethylene glycol ethers, petrochemicals, benzene, perchloroethylene, and radiation can lower sperm quality, quantity and possibly lead to infertility or miscarriage.


Eat and sleep

What you eat can make a difference. Find out what your proper weight range should be and make the necessary dietary and exercise changes to get there. Studies suggest that some men with low sperm count also have a zinc deficiency.

The following foods are high in zinc and could increase your fertility:
 



Adding more vitamin e may also help the process along. There are male fertility supplements available containing vitamins, minerals and other ingredients designed to help improve overall reproductive health.

Also, keep in mind getting plenty of rest is good for everything that ails you, even low sperm count and sperm quality.

Avoid alcohol and other substances

Eliminate alcohol, tobacco, marijuana and any illicit drugs. Too much alcohol may reduce zinc levels, and drugs decrease sperm quality. There is some research that may link smoking and certain rare heart defects, but further studies must be done to make an accurate conclusion. Marijuana has been proven to affect sperm quality and sperm count, but there is no evidence that shows that marijuana causes birth defects.

Keep your testicles cool

Heat from hot tubs, saunas, long showers (more than 30 minutes), heating pads, electric blankets, and tight clothing like briefs and spandex could cause your testicles to become too hot, which decreases sperm quantity.

Stay away from cycling

Cycling can cause a lot of friction and jostling, which increases the temperature of your testicles. The rise in temperature and possibility of injury may cause a low sperm count.

 

7 people found this helpful

Gastroesophageal Reflux Disease(GERD) - What To Expect?

MBBS, MD-General Medicine, DM-Gastroenterology, Advanced endoscopy fellowship
Gastroenterologist, Visakhapatnam
Gastroesophageal Reflux Disease(GERD) - What To Expect?

Gastroesophageal Reflux Disease (GERD) is a form of digestive disorder, which affects the lower oesophageal sphincters or the muscle ring present between the stomach and the food pipe. GERD incorporates the return of the contents of the stomach back to the oesophagus or food pipe. The functioning of the lower oesophageal sphincter is disrupted.

Causes-

Hiatal hernia is a common cause of GERD. An unhealthy lifestyle and diet may also lead to GERD. Intake of an excess amount of chocolates, fried food, coffee or alcohol triggers the chance of a reflux. GERD also occurs in obese people and pregnant women.

Symptoms-

Heartburn, also known as acid indigestion, is the primary symptom of GERD. The affected person may feel a burning chest pain which starts from behind the breastbone and reaches up to the throat. The feeling can be defined as food coming back to the throat with a bitter, acidic taste. The burning sensation may last as long as two hours.

Other symptoms include:

In order to diagnose GERD, several tests may be conducted . They are:

  1. An X-Ray of the upper part of the digestive system.
  2. Endoscopy to examine the inner part of the oesophagus.
  3. Ambulatory acid test for monitoring the amount of acid within the oesophagus.
  4. An oesophageal impedance test to measure substance movement inside the oesophagus.

Treatment-

  1. Proton pump inhibitors (PPIs) are one type of medication that can be used to reduce stomach acid and relieve GERD symptoms.A person must make several changes to his daily lifestyle and diet plan for treatment of GERD. PPIs work by blocking and reducing the production of stomach acid. This gives any damaged esophageal tissue time to heal. PPIs also help prevent heartburn, the burning sensation that often accompanies GERD.
  2. Food and beverages like chocolates, fatty food, coffee, alcohol and peppermint should be avoided in order to reduce the weakening of the lower oesophageal sphincter. Several food items irritate the damaged oesophageal lining and should also be avoided. They include citrus fruits, tomato and pepper.
  3. Smoking cigarettes results in weakening of the lower oesophageal sphincter and should be stopped to reduce GERD.
  4. One should elevate the head of the bed on which he or she sleeps on blocks measuring 6 inches. This reduces the heartburn as gravity minimizes stomach reflux to return to the oesophagus.
  5. Over the counter medicines can be used to cure GERD. Antacids are a good example and neutralize the acid in the oesophagus and stomach, reducing heartburn. Combining antacids with foaming agents is also effective. A foam barrier is formed over the stomach, preventing the occurrence of acid reflux.

Medicines for reducing acid in the stomach are prescribed in cases of chronic GERD, which include H2 blockers by the likes of cimetidine, famotidine or nizatidine.

GERD is a digestive disorder which causes disruption in digestion, as reflux from the stomach is returned to the oesophagus. Proper treatment measures should be taken.

In case you have a concern or query you can always consult an expert & get answers to your questions!

3346 people found this helpful

Table of Content

About Cimetidine
When is Cimetidine prescribed?
What are the contraindications of Cimetidine ?
What are the side effects of Cimetidine ?
Key highlights of Cimetidine
What are the dosage instructions?
Where is the Cimetidine approved?
How does medicine works?
What are the interactions for Cimetidine ?