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Overview

Casodex 50mg Tablet

Manufacturer: Astra Zeneca
Medicine composition: Bicalutamide
Prescription vs.OTC: Prescription by Doctor required

A non-steroidal anti-androgen, Casodex 50mg Tablet is used in combination with a gonadotropin-releasing hormone for treating prostate cancer. It works by blocking the action of testosterone. This medicine may also be used prevent priapism, to treat excessive hair growth in women and to treat early puberty in boys. It also acts as a component of hormone therapy for transgender women.

Common side effects of Casodex 50mg Tablet in men include breast tenderness, breast enlargement and hot flashes. Some other side effects in men include sexual dysfunction and feminisation. It can also cause lung toxicity and liver damage. Common side effects that may occur include constipation, diarrhoea, abdominal pain, itching, nausea, dry skin and rash.

Inform your doctor before taking this medicine if you are pregnant, planning to become pregnant or breastfeeding. Do not take this medicine if you are allergic to it. Some medicines like oral anti-coagulants and midazolam can interact with its actions so inform your doctor if you are taking these medications.

This medicine is taken by mouth, with or without food. It is usually taken once a day. Follow your doctor’s prescription carefully and do not increase or decrease your dose without the doctor’s approval.

In addition to its intended effect, Casodex 50mg Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Rash
Decreased libido
Breast enlargement in male
Weakness
Dyspepsia
Weight gain
Increased liver enzymes
Breast tenderness
Decreased appetite
Flatulence
Hot flashes.
Is It safe with alcohol?
Interaction with alcohol is unknown. Please consult your doctor.
Are there any pregnancy warnings?
Caludec 50mg tablet is highly unsafe to use during pregnancy.
Human and animal studies have shown significant adverse effects on the foetus. Please consult your doctor.
Are there any breast-feeding warnings?
Caludec 50mg tablet is probably unsafe to use during breastfeeding. Please consult your doctor.
Is it safe to drive while on this medicine?
Patients experiencing undesirable effects like somnolence should not drive or use machines.
Does this affect kidney function?
There is no interaction between renal impairment and consuming this drug. So dose alteration is not needed.
Does this affect liver function?
There is no data available. Please consult doctor before consuming the drug.
Below is the list of medicines, which have the same composition, strength and form as Casodex 50mg Tablet, and hence can be used as its substitute.
Sun Pharmaceutical Industries Ltd
Intas Pharmaceuticals Ltd
Dr Reddy s Laboratories Ltd
Alkem Laboratories Ltd
Emcure Pharmaceuticals Ltd
Oster Remedies
Sun Pharmaceutical Industries Ltd
Neon Laboratories Ltd
Hetero Drugs Ltd
Samarth Life Sciences Pvt Ltd
Zydus Cadila
Celon Laboratories Ltd
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Interaction with Medicine
Acitrom 4Mg Tablet
Acenomac 3Mg Tablet
Acenomac 1Mg Tablet
Acenomac 2Mg Tablet
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

September 2013 I was diagnosed with Advanced Metastatic Prostate by DRE, a T4 large lesion invading the outer rectum. A 328 urg/l on Lucrin and bicalutamide afer 12 months I changed to Zoladex 3 monthly injections because of side effects namely loss of muscle and pain.

DNB (Urology), MS (Gen Surgen), MBBS
Urologist, Faridabad
The question is not very clear. If you have a metastatic ca prostate and you were put on hormone ablation therapy your disease should be regularly monitored with your psa values.
3 people found this helpful

I was a Prostate Cancer Patient stage 4, metastatized to Lymph Nodes and PSA 560. I underwent Orchidectomy Surgery and PSA steadily came down to 8 in 3 Months, 3 in 6 months, 2. in 9 months and 1.2 in ONE YEAR. Am I Cancer FREE or Cancer Cured or Cancer Controlled? What Further should I do to Prevent it from Recurrence?

MD - Radiothrapy
Oncologist, Gurgaon
No , if you have underwent orchidectomy only then its incomplete treatment in your case . Also i would like to know what was the Gleason score and was there any bone scan abnormality. You should start taking Tab Bicalutamide 50 mg OD and also get a PSMA scan done.
2 people found this helpful

I have been suffering from enlargement of prostrate for last 2 years. During October 2015 my PSA was detected at 10.92.Thereafter I underwent TRUS and prostrate BX. But it revealed no sign of malignancy. However immediately after Prostrate BX, I was fallen acutely sick with complete retention of Urine. Accordingly, I was hospitalized in January 2016 and treated with iv injection and catheterization. At the time of discharge after one week with catheter in situ, I was advised to go for TURP at the earliest. However, I was not in favor of surgery. Hence, I had made consultation with another surgeon in last week of January 2016 and based on his advice I have undergone MRI Prostrate .PI Rads of MRI is 3/5. Depending on the report, he prescribed me the medicine contiflo-D and advised me to report after 1.5 months with PSA Report. Accordingly, I made report to him in FEBRUARY 2016 WTH MY PSA reading at 8.05. On going through the report, the doctor removed my catheter, prescribed the same medicine –contiflo-D, and asked me to report again in May 2015 with PSA REPORT. On 7th. May 2016, I visited the doctor with PSA reading at 6.05.The doctor then prescribed me Urimax-D and Calutide-50. In replacement of the earlier prescribed medicine. However on consuming Calutide-50, I being a bronchial Asthma patient, developed breathing problem. Accordingly, I made my PSA test on 13.06.2016 and visited doctor on 15.06.2016 with PSA report of 2.72 .On going through the report the doctor advised me to continue other medicine excepting Calutide and report after 03 months with report on PSA and Haemoglobin. I have made my PSA and haemoglobin on 02.11.2016 and the report of test reveals that PSA has been elevated to 5.27 while haemoglobin % has also increased from 14.0 to 14.4.With the report I have consulted my Urologist on 05.11.2016 and due to elevation of PSA he has advised me to continue Calutide again. I have learnt from my chemist that the medicine Calutide is generally prescribed for treatment of Prostate cancer. I am rather worried if I have been suffering from the said Incurable disease. In view of the above, kindly inform me if Calutide can also be prescribed for BPH. Regards.

MBBS,, MS,MRCS(Edinburgh),MCh Urology
Urologist, Mysore
I have been suffering from enlargement of prostrate for last 2 years. During October 2015 my PSA was detected at 10.9...
Hi lybrate-user ,understood your problem, you underwent PI rads of MRI .PI rads (Prostate Imaging Reporting and Data System) PI-RADS 1: very low (clinically significant cancer is highly unlikely to be present) PI-RADS 2: low (clinically significant cancer is unlikely to be present) PI-RADS 3: intermediate (the presence of clinically significant cancer is equivocal) PI-RADS 4: high (clinically significant cancer is likely to be present) PI-RADS 5: very high (clinically significant cancer is highly likely to be present) your score of MRI is equivocal ,PSA is fluctuating ,Bicalutamide was added in view of Ca Prostate not for BPH.
1 person found this helpful

My grandfather is 80 years old has swelling of prostate gland and left leg feeling as if it is paralysed. MBBS Dr. had recommended him tablet Calutide 50 and capsule Tinosporine but now capsule Tinosporine isn't available in the market so what will be the substitute for this?

MBBS
General Physician, Cuttack
It could be due to carcinoma prostate. Take USG pelvis, do PSA examination after Consuling a Urologist and follow the advice and treatment accordingly.
1 person found this helpful

Table of Content

About Casodex 50mg Tablet
When is Casodex 50mg Tablet prescribed?
What are the side effects of Casodex 50mg Tablet?
Key highlights of Casodex 50mg Tablet
What are the substitutes for Casodex 50mg Tablet?
What are the interactions for Casodex 50mg Tablet?