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Overview

Azaprin Tablet

Manufacturer: Galcare Pharmaceutical Pvt Ltd
Medicine composition: Azathioprine
Prescription vs.OTC: Prescription by Doctor required

Azaprin Tablet acts as an immuno-suppressant drug, which is used to treat ulcerative colitis, rheumatoid arthritis, Crohn's disease, and in kidney transplants to prevent the rejection of a new kidney. Azaprin Tablet is also an anti-metabolite. It works by lowering the body's immune system against the transplanted kidney. Close monitoring of blood cell count is necessary while taking this medication so It should be used under the supervision of a qualified physician. It can be administered by mouth or injected into a vein.

Do not use this medicine if you are allergic to any ingredient in Azaprin Tablet; if you are pregnant, if you have used alkylating agents in the past, or you are currently taking febuxostat or mercaptopurine. Inform your doctor if you have the following medical conditions to make sure this medicine will be safe for you :

  • kidney or liver disorders
  • bowel problems
  • a history of frequent, recurrent, or prolonged infection
  • scheduled to receive a vaccination or immunisation shortly.
  • a history of cancer, anaemia, bone marrow problems, unusual bruising or bleeding, or low white blood cell or platelet levels.
  • any enzyme deficiencies or recent blood transfusions.

Take this medication with food to reduce stomach upset. Dosage is as directed by your doctor, usually once or twice daily. The dosage is based on your weight, medical condition and response to treatment. If you increase your dose or use this drug more often or for longer than prescribed then you may increase the risk of it's side-effects.

Kidney Transplantation
Azaprin Tablet is used in kidney transplant patients to prevent transplant rejection.
Azaprin Tablet is used in the treatment of rheumatoid arthritis which is an inflammatory disease characerized by swelling, pain, and stiffness of joints.
Not recommended in patients with known allergy to Azaprin Tablet.
Alkylating agents
Not recommended in patients with rheumatoid arthritis previously treated with cyclophosphamide, chlorambucil.
In addition to its intended effect, Azaprin Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Fever with chills Major Common
Sore throat Major Common
Abdominal pain Major Rare
Loss of appetite Major Rare
Muscle and joint pain Major Rare
Nausea and Vomiting Minor Common
Hair loss or thinning of the hair Minor Rare
Duration of effect
The duration of action of this medicine is not clinically established.
Onset of action
The effect of this medicine can be observed in 1 to 2 hours.
Pregnancy warnings
This medicine is not recommended for pregnant women.
Is it habit forming?
No habit forming tendencies were reported.
Breast-feeding warnings
This medicine is not recommended in breastfeeding women.
Below is the list of medicines, which have the same composition, strength and form as Azaprin Tablet, and hence can be used as its substitute.
Tas Med India Pvt Ltd
Canixa Life Sciences Pvt
Ipca Laboratories Ltd
Intas Pharmaceuticals Ltd
Chandra Bhagat Pharma Pvt Ltd
Missed Dose instructions
If you miss a dose of Azaprin Tablet, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
Overdose instructions
Seek emergency medical treatment or contact the doctor in case of an overdose.
India
United States
Japan
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Interaction with Disease
Disease
Information not available.
Interaction with Alcohol
Alcohol
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Lab Test
Lab
Information not available.
Interaction with Food
Food
Information not available.
Interaction with Medicine
Warfarin Moderate
This medicine may decrease the effect of warfarin. Inform the doctor if you are receiving either of the medications.Seek immediate medical treatment if you have any symptoms of breathing problem, blurred vision, blood clots and swelling of limbs.
Angiotensin converting enzyme inhibitors Moderate
These medications may lower the WBC count and may increase the risk of infections. Usage of antihypertensive medications like enalapril, ramipril, captopril should be reported to the doctor. Seek immediate medical treatment if you have any symptoms of infection like fever, chills, diarrhea, sore throat.
Live attenuated vaccines and related products Major
You may be at the risk of developing infections if these medicines are taken together. Inform the doctor if you had received either of these medicines. Your doctor may postpone therapy based on the condition.
What are you using Azaprin Tablet for?
Rheumatoid Arthritis
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

I have crohns disease and recently detected h pylori. I have been taking azathioprine for crohns and its been in control. But now I have to start triple therapy for h pylori eradication. Is there any side effects or interactions when azathioprine and triple therapy drugs used simultaneously?

MD-General Medicine, D.M, Gastroenterology & Hepatology
Gastroenterologist, Ahmedabad
I have crohns disease and recently detected h pylori. I have been taking azathioprine for crohns and its been in cont...
No, you may get a bad taste in the mouth or have loose stools for a few days due to the antibiotics, but the therapy will not affect the Crohn’s disease.
2 people found this helpful

I am 31 years female. I am suffering from Myasthenia gravis. Since 3 months I have taken Pyridostigmine 2/day and prednisolone 3/day and azathioprine 2 /day. After I take pills I am very tired. Kindly advice.

MD(EH)/AM/Accupressure
Homeopath, Chandigarh
If this medicine suits you then you may reduce the dz. After that you can watch that you r tired or not. What kind of weakness you r feeling. Take bio. 20 three times a day for two days twice daily.
1 person found this helpful

Hlo sir, which medicine is best for rheumatoid arthritis. Methotrexate or azathioprine, mycophenoltae mofetil? Plzz give me advise which medicine is best to cure the disease *(rheumatoid arthritis ).

Erasmus Mundus Master in Adapted Physical Activity, MPT, BPTh/BPT
Physiotherapist, Chennai
Hlo sir, which medicine is best for rheumatoid arthritis. Methotrexate or azathioprine, mycophenoltae mofetil? Plzz g...
Rheumatic arthritisIt is called as Rheumatic arthritis. If your pain is more in the distal joints, ie. In the upper limbs if the pain is present in the fingers/wrist and in the lower limbs it the pain is present in the toes/ ankle, then we shall definitely say it is Rheumatic arthritis. Wear elbow brace and wrist brace which will make her to feel warm and that will make the joints become firm. Hot water fermentation will help Knee cap will also help to prevent the damaged cartilages. If your pain is more in the distal joints, ie. In the upper limbs if the pain is present in the fingers/wrist and in the lower limbs it the pain is present in the toes/ ankle, then we shall definitely say it is Rheumatic arthritis. Which joints you have pain? If your proximal joints (ie. Shoulder, hip & knee has pain) then you can pour hot (warm) water in that area to reduce the inflammation. If you have pain in the distal joints ie. Wrist, fingers, ankle, toes then you can wear either elbow brace or wrist brace which will help you to feel warm and very protective. And also immerse the distal joints in the hot water tub which will help you to reduce the pain. Consult the near by physiotherapy clinic and also consult a general physician to check with your ESR levels to check whether you have inflammation The sound what you hear is called as Crepitus /ˈkrɛpɪtəs/ (also termed crepitation) is a medical term to describe the grating, crackling or popping sounds and sensations experienced under the skin and joints or a crackling sensation due to the presence of air in the subcutaneous tissue. Popping Knees and Crackling Knuckles. Occasionally hearing pops, snaps, and crackles when you bend your knees doesn’t necessarily mean you have arthritis. The kneecap (patella) is the small, convex bone that sits at the front of the knee, shielding the joint.

I am 28 years old, have been on T medrol steroid for 3 months (Nov-Jan), since then I am on azathioprine, azoran, folvite, pentids 800 due to Multiple sclerosis (an autoimmunity disorder), having a lot of hair fall since a month, got my blood checkup done and it showed up iron deficiency, I would like to know if steroid is showing after affects, or it is the iron content or azathioprine, according to internet all of it can cause hair fall. Please advice how can this be treated? Have been to a dermatologist and I am using some minoxidil spray as well as consuming FOLLIHAIR TABLET once daily, no improvement since 15 days, hair fall has gone upto 300 strands a day.

CIDESCO, DGA, DBT, DBC, MBBS
Trichologist, Mumbai
I am 28 years old, have been on T medrol steroid for 3 months (Nov-Jan), since then I am on azathioprine, azoran, fol...
Hello Sneha . yeah both excessive steroid use n low iron levels causes hair fall problems. u cn start having , cap estemo once a day after food for 3 mths. cap eracod once a day after food for 3 mths. tab ener c dissolvable tab early morning empty stomach for 3 mths. use mild medicated shampoo like triclenz hair shampoo for regular use. Use minotress hair solution 5% on scalp for two times per day for 3 mths. n hair problems take long tym to treated so hv patience. drink 2-3 lit of water daily include protein rich foods in ur diet, include green leafy vegetables and fresh fruits in ur diet ,exercise 45 min daily. thanks
2 people found this helpful

Popular Health Tips

What Are The Causes and Symptoms of Sweet's Syndrome?

MD - Dermatology, MBBS
Dermatologist, Bangalore
What Are The Causes and Symptoms of Sweet's Syndrome?

Sweet's syndrome is when you suffer from fever as well as painful skin lesions. These skin lesions usually appear on your head, arms and neck. The cause of Sweet's syndrome is still not known. However, it is known that certain medications, illnesses and infections are a possible trigger for Sweet's syndrome. Sweet's syndrome is such a condition that the symptoms usually go away in a few days but it may come back later on. To know exactly what causes Sweet's syndrome and what the symptoms of it are, read on.

Causes and Risk Factors:
As mentioned earlier, the exact cause of Sweet's syndrome is not known. However, there are certain factors which put you more at risk of getting it than others. Here they are: 

  1. Gender: It has been proven that women are much more likely to get Sweet's syndrome than men.
  2. Age: The young and the elderly are at a risk of getting Sweet's syndrome. However, if you are in between 30 and 60 years of age you are especially at risk.
  3. Illnesses: If you have an upper respiratory infection or inflammatory bowel disease then you are more likely to get Sweet's syndrome compared to others. Flu-like symptoms also put you more at a risk of getting Sweet's syndrome compared to others.
  4. Pregnancy: It has been seen that pregnancy increases your risk of getting Sweet's syndrome.
  5. Drugs: As mentioned earlier, certain antibiotics, nonsteroidal anti-inflammatory drugs as well as azathioprine are all linked to Sweet's syndrome.

Symptoms-

  1. Small Red Bumps: As mentioned earlier, the main symptom of Sweet's syndrome is that you will develop small red bumps on your neck, arms or head. The size of the bumps tend to increase quickly and then they spread into painful clusters.
  2. Fever: A fever is also very symptomatic of Sweet's syndrome. The small red bumps usually appear abruptly after you get a fever.
  3. Upper Respiratory Infection: The small red bumps also appear abruptly after you have got an upper respiratory Infection.

It should be noted that Sweet's syndrome is often associated with cancer and has commonly been linked to leukemia. If you wish to discuss about any specific problem, you can consult a Dermatologist.

2869 people found this helpful

Uveitis - Do You Know It Can Increase The Risk Of Other Diseases?

MBBS, MS - Ophthalmology
Ophthalmologist, Ghaziabad
Uveitis - Do You Know It Can Increase The Risk Of Other Diseases?

Uveitis is a set of inflammatory diseases that results in the swelling and damaging of the eye tissue. It can lead to temporary or permanent loss of vision. This disease often affects a part of the eye called the uvea, from which it has derived its name. It can affect people of all ages and can last from a short to long period of time. Ophthalmologists categorize uveitis into four major parts posterior uveitis, anterior uveitis, panuveitis uveitis and intermediate uveitis. This disease can be infectious or noninfectious, depending on the nature of the infection.

What causes uveitis and what are the major risk factors?
This disease is caused by the eye's inflammatory response and is caused by a series of potential factors such as the following:

  • Immune system attack from the body
  • Eye bruises
  • Eye infection or tumor within the eye
  • Foreign toxins that penetrate the eye

What are the diseases associated with uveitis?
Uveitis is associated with a range of diseases such as multiple sclerosis, Behcet's syndrome, Vogt-Koyanagi-Harada's (VKH) disease, psoriasis, herpes zoster infection, tuberculosis, rheumatoid arthritis, ulcerative colitis, toxoplasmosis, and cytomegalovirus (CMV) retinitis.

What are the typical symptoms of uveitis?
One or both eyes can be affected by uveitis. Some of the common symptoms include pain in the eye, light sensitivity and blurred and dark spots in vision. Moreover, the symptoms might vary from person to person and greatly depends on the type of inflammation. The symptoms also vary according to the type of uveitis.

What is the detection process?
The process of detection starts with a patient's medical history followed by several medical tests to rule out autoimmune disorders. This is followed by an evaluation of the central nervous system to rule out multiple sclerosis. Some of the other tests conducted by ophthalmologists include measuring the ocular pressure, slit lamp exam, funduscopic exam and visual acuity test.

The primary aim of the treatment is to eradicate inflammation, restore vision, prevent tissue damage and reduce pain. The treatment plan depends on the type of uveitis a patient displays. Doctors often suggest a dose of corticosteroid eye drops to arrest the infection in and around the eye. Other treatment methods include the prescription of immunosuppressive agents.

Furthermore, a doctor may suggest steroidal medication in the form of an eye drop, pill or injection. It can also be surgically infused into the eye. Some other agents used for treatment are azathioprine, methotrexate and mycophenolate. Medications such as these require regular monitoring of the blood to check for any side effects. Doctors also suggest biologics such as infliximab, rituximab, and adalimumab. Most of these drugs have a specific target in the immune system.

In case you have a concern or query you can always consult an expert & get answers to your questions!

5044 people found this helpful

Uveitis - Know How It Can Be Diagnosed!

ABC
Ophthalmologist, Jodhpur
Uveitis - Know How It Can Be Diagnosed!

Uveitis is a set of inflammatory diseases that results in the swelling and damaging of the eye tissue. It can lead to temporary or permanent loss of vision. This disease often affects a part of the eye called the uvea, from which it has derived its name. It can affect people of all ages and can last from a short to long period of time. Ophthalmologists categorize uveitis into four major parts posterior uveitis, anterior uveitis, panuveitis uveitis and intermediate uveitis. This disease can be infectious or noninfectious, depending on the nature of the infection.

What causes uveitis and what are the major risk factors?
This disease is caused by the eye's inflammatory response and is caused by a series of potential factors such as the following:

  • Immune system attack from the body
  • Eye bruises
  • Eye infection or tumor within the eye
  • Foreign toxins that penetrate the eye

What are the diseases associated with uveitis?
Uveitis is associated with a range of diseases such as multiple sclerosis, Behcet's syndrome, Vogt-Koyanagi-Harada's (VKH) disease, psoriasis, herpes zoster infection, tuberculosis, rheumatoid arthritis, ulcerative colitis, toxoplasmosis, and cytomegalovirus (CMV) retinitis.

What are the typical symptoms of uveitis?

One or both eyes can be affected by uveitis. Some of the common symptoms include pain in the eye, light sensitivity and blurred and dark spots in vision. Moreover, the symptoms might vary from person to person and greatly depends on the type of inflammation. The symptoms also vary according to the type of uveitis.

What is the detection process?
The process of detection starts with a patient's medical history followed by several medical tests to rule out autoimmune disorders. This is followed by an evaluation of the central nervous system to rule out multiple sclerosis. Some of the other tests conducted by ophthalmologists include measuring the ocular pressure, slit lamp exam, funduscopic exam and visual acuity test.

The primary aim of the treatment is to eradicate inflammation, restore vision, prevent tissue damage and reduce pain. The treatment plan depends on the type of uveitis a patient displays. Doctors often suggest a dose of corticosteroid eye drops to arrest the infection in and around the eye. Other treatment methods include the prescription of immunosuppressive agents.

Furthermore, a doctor may suggest steroidal medication in the form of an eye drop, pill or injection. It can also be surgically infused into the eye. Some other agents used for treatment are azathioprine, methotrexate and mycophenolate. Medications such as these require regular monitoring of the blood to check for any side effects. Doctors also suggest biologics such as infliximab, rituximab, and adalimumab. Most of these drugs have a specific target in the immune system.

In case you have a concern or query you can always consult an expert & get answers to your questions!

6486 people found this helpful

Sweet's Syndrome - Common Risk Factors Associated With It!

MD - Dermatology
Dermatologist, Bathinda
Sweet's Syndrome - Common Risk Factors Associated With It!

Sweet's syndrome is when you suffer from fever as well as painful skin lesions. These skin lesions usually appear on your head, arms and neck. The cause of Sweet's syndrome is still not known. However, it is known that certain medications, illnesses and infections are a possible trigger for Sweet's syndrome. Sweet's syndrome is such a condition that the symptoms usually go away in a few days but it may come back later on. To know exactly what causes Sweet's syndrome and what the symptoms of it are, read on.

Causes and Risk Factors:
As mentioned earlier, the exact cause of Sweet's syndrome is not known. However, there are certain factors which put you more at risk of getting it than others. Here they are: 

  1. Gender: It has been proven that women are much more likely to get Sweet's syndrome than men.
  2. Age: The young and the elderly are at a risk of getting Sweet's syndrome. However, if you are in between 30 and 60 years of age you are especially at risk.
  3. Illnesses: If you have an upper respiratory infection or inflammatory bowel disease then you are more likely to get Sweet's syndrome compared to others. Flu-like symptoms also put you more at a risk of getting Sweet's syndrome compared to others.
  4. Pregnancy: It has been seen that pregnancy increases your risk of getting Sweet's syndrome.
  5. Drugs: As mentioned earlier, certain antibiotics, nonsteroidal anti-inflammatory drugs as well as azathioprine are all linked to Sweet's syndrome.

Symptoms-

  1. Small Red Bumps: As mentioned earlier, the main symptom of Sweet's syndrome is that you will develop small red bumps on your neck, arms or head. The size of the bumps tend to increase quickly and then they spread into painful clusters.
  2. Fever: A fever is also very symptomatic of Sweet's syndrome. The small red bumps usually appear abruptly after you get a fever.
  3. Upper Respiratory Infection: The small red bumps also appear abruptly after you have got an upper respiratory Infection.

It should be noted that Sweet's syndrome is often associated with cancer and has commonly been linked to leukemia. If you wish to discuss about any specific problem, you can consult a dermatologist.

1 person found this helpful

Causes and Symptoms of Sweet's Syndrome

MBBS, MD - Dermatology , Venereology & Leprosy
Dermatologist, Ghaziabad
Causes and Symptoms of Sweet's Syndrome

Sweet's syndrome is when you suffer from fever as well as painful skin lesions. These skin lesions usually appear on your head, arms and neck. The cause of Sweet's syndrome is still not known. However, it is known that certain medications, illnesses and infections are a possible trigger for Sweet's syndrome. Sweet's syndrome is such a condition that the symptoms usually go away in a few days but it may come back later on. To know exactly what causes Sweet's syndrome and what the symptoms of it are, read on.

Causes and Risk Factors:
As mentioned earlier, the exact cause of Sweet's syndrome is not known. However, there are certain factors which put you more at risk of getting it than others. Here they are: 

  1. Gender: It has been proven that women are much more likely to get Sweet's syndrome than men.
  2. Age: The young and the elderly are at a risk of getting Sweet's syndrome. However, if you are in between 30 and 60 years of age you are especially at risk.
  3. Illnesses: If you have an upper respiratory infection or inflammatory bowel disease then you are more likely to get Sweet's syndrome compared to others. Flu-like symptoms also put you more at a risk of getting Sweet's syndrome compared to others.
  4. Pregnancy: It has been seen that pregnancy increases your risk of getting Sweet's syndrome.
  5. Drugs: As mentioned earlier, certain antibiotics, nonsteroidal anti-inflammatory drugs as well as azathioprine are all linked to Sweet's syndrome.

Symptoms-

  1. Small Red Bumps: As mentioned earlier, the main symptom of Sweet's syndrome is that you will develop small red bumps on your neck, arms or head. The size of the bumps tend to increase quickly and then they spread into painful clusters.
  2. Fever: A fever is also very symptomatic of Sweet's syndrome. The small red bumps usually appear abruptly after you get a fever.
  3. Upper Respiratory Infection: The small red bumps also appear abruptly after you have got an upper respiratory Infection.

It should be noted that Sweet's syndrome is often associated with cancer and has commonly been linked to leukemia. If you wish to discuss about any specific problem, you can consult a dermatologist.

2736 people found this helpful

Table of Content

About Azaprin Tablet
When is Azaprin Tablet prescribed?
What are the contraindications of Azaprin Tablet?
What are the side effects of Azaprin Tablet?
Key highlights of Azaprin Tablet
What are the substitutes for Azaprin Tablet?
What are the dosage instructions?
Where is the Azaprin Tablet approved?
What are the interactions for Azaprin Tablet?